Downtown San Francisco Holidays from £702

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Your Downtown San Francisco Holiday

From its history to its shopping and culture, there are so many good reasons to book a holiday package to Downtown San Francisco. When it's time to get away from it all, this busy neighbourhood will be your home away from home. Kick start your trip to Downtown San Francisco with a visit to nearby attractions such as Pier 39, Alcatraz Island and Lombard Street. No matter your travel plans or the size of your budget, booking your perfect Downtown San Francisco holiday is easy with Expedia.

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
per person
8 Sept - 13 Sept
found 11 hours ago
Return direct flight included
London (LHR) to San Francisco (SFO)
9/10 Wonderful! (6,533 reviews)
Distance from the piers

Reviewed on 29 Jul 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
per person
23 Sept - 27 Sept
found 21 hours ago
Return direct flight included
London (LON) to San Francisco (SFO)
9.2/10 Wonderful! (419 reviews)
A beautiful hotel. Most staff were lovely - unnecessary friction with a couple. The facilities that the hotel has are impeccable - b

Reviewed on 26 Jul 2025

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
Fisherman's Wharf
per person
8 Sept - 13 Sept
found 11 hours ago
Return direct flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (1,338 reviews)
It was a great location. We walked to Pier 39 and the Fisherman’s Wharf. Room service and valet service were easy and quick! Rooms were a bit small, but were very clean!

Reviewed on 29 Jul 2025

Inn At The Opera

Inn At The Opera

3.5 out of 5
Fillmore District
Save 100% on your flight
per person
22 Sept - 29 Sept
found 21 hours ago
Return direct flight included
London (LON) to San Francisco (SFO)
8.4/10 Very Good! (691 reviews)
Enjoyed the atmosphere of this inn. Very cute and decorated nicely. Love the ballet theme on our room.

Reviewed on 13 Jul 2025

The Donatello

The Donatello

3.5 out of 5
Union Square
per person
8 Sept - 13 Sept
found 11 hours ago
Return direct flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (1,000 reviews)
Staff was incredibly helpful and pleasant. Nancy, the Donatello manager, was fantastic at resolving a reservation issue that we encountered.

Reviewed on 27 Jul 2025

Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

1 out of top 10 points of interest in this area
5/5(4 area reviews)

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Top hotels in Downtown San Francisco

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is £115 per night from 24 Aug to 25 Aug
£115
24 Aug - 25 Aug
includes taxes & fees
8.8/10 Excellent! (4,354 reviews)
"Was very worried about my car being broken into because of the news. This hotel was lovely clean, great restaurant inside. Loved the gated parking made me feel safe."

Reviewed on 29 Jul 2025

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £103 per night from 24 Aug to 25 Aug
£103
24 Aug - 25 Aug
includes taxes & fees
8.6/10 Excellent! (1,539 reviews)
Still a fave
"The check in staff, housekeeping and our waiter Hourai (sp) were awesome. Hourai remembered us and our drink choices. This is our fave and only hotel"

Reviewed on 28 Jul 2025

Hilton San Francisco Financial District
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £177 per night from 28 Aug to 29 Aug
£177
28 Aug - 29 Aug
includes taxes & fees
9.2/10 Wonderful! (1,780 reviews)
"The view from our hotel was amazing and the location was super convenient"

Reviewed on 28 Jul 2025

Hyatt Regency San Francisco
See all 980 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

Why should I book my Downtown San Francisco holiday with Expedia?
With excellent-value flights, car hire and accommodation options all in one place, Expedia makes arranging your Downtown San Francisco break simple. Moreover, we can help you bundle your bookings into a package holiday so you can save even more. Pick from fabulous escapes, add your flights and/or a hire car (and maybe also some exciting activities!) and get unbeatable prices. Need to change your plans? Expedia offers a flexible cancellation policy for many bookings. To discover more, make your way to our Customer Service Portal link.
What are the top hotels for my holiday in Downtown San Francisco?
Get your trip off to a good start by booking a room at Globe Hotel San Francisco SoMa. It's one of the most sought-after properties for those wanting to be near Downtown San Francisco. Another welcoming option close by is ITH Pacific Tradewinds Hostel.
How do I get a cheap holiday to Downtown San Francisco?
Browse and book everything in the one place with our Downtown San Francisco holidays. You'll find bargains on hotels, flights and more that'll keep your bank account happy and your sense of adventure alive. And, with more than 400 air carriers and 321,000 hotels worldwide to pick from, there are endless opportunities to mix and match as you like. Learn more about how you can save money on your next holiday when you bundle your flight and hotel bookings with Expedia.
What should I do on my Downtown San Francisco holiday?
Offering popular attractions like Pier 39 and Alcatraz Island, a holiday in Downtown San Francisco promises lots of fun things to do and see. Lombard Street and San Francisco State University are two other sights worth discovering.
What is the best area to stay in when on holiday in Downtown San Francisco?
Downtown San Francisco has a number of interesting places to explore, including Oracle Park. Stay somewhere close by and make sightseeing hassle-free.
Do I need a visa for my Downtown San Francisco holiday?
Visa requirements for Downtown San Francisco vary based on your nationality and the purpose of your visit. Make sure you check official government websites to determine if you need a visa for your trip. Here you'll also find the most up-to-date information, including details about application procedures or any supporting documentation that might be necessary. Research your visa requirements in advance to ensure a hassle-free travel experience. Also check to see that your passport has at least six months validity from your planned return date.
What should I wear on my Downtown San Francisco holiday?
Consider the types of activities you'll be doing during your Downtown San Francisco holiday and create a travel wardrobe that you can mix and match. For fashion inspiration or even information on dress codes, look up style blogs or social media accounts.
What does an Expedia Downtown San Francisco holiday include?
Choose from a combination of hire cars, hotels and flights. Once you've made your booking, add the fun stuff like experiences and tours. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to organising your dream Downtown San Francisco trip. Expedia offers a wide selection of properties in Downtown San Francisco, giving you the flexibility and freedom to personalise your escape. Apartments and private holiday homes are some of the most popular stays for our guests here.
Does Expedia offer Book Now, Pay Later Downtown San Francisco holidays?
We certainly do. Expedia has teamed up with online lender Klarna to help you easily pay for your trip in instalments. Simply click on the payment plan that works for you during the checkout process and take away the stress of budgeting for your next trip. Make sure you bundle your flights, hotel and car hire with Expedia to get the biggest bang for your buck. Check out our flexible payment options below:

  • Pay monthly holidays: Klarna offers easy monthly payment plans that work for all budgets, so you can book that well-deserved holiday sooner.
  • No-deposit holidays: Pressing the "book now" button is much easier with this payment option. With no upfront fee for your escape, you can Book Now, Pay Later and start working on your travel itinerary.

Can I choose my airline with a Downtown San Francisco Expedia holiday?
Yes, and with over 400 airlines to select from throughout the world, it's all about choice. Search the available options and find out which airline fits your budget and needs.

Popular places to visit

Oracle Park

Oracle Park

4.5/5(24 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Moscone Convention Center

Moscone Convention Center

4/5(13 reviews)

During your trip, find out what's happening in Moscone Convention Center, a top convention centre in San Francisco. Discover the fascinating museums and notable monuments in this vibrant area.

Moscone Convention Center
Union Square

Union Square

4.5/5(9 reviews)

You can browse for the perfect souvenirs at Union Square during your stay in San Francisco. Discover the top-notch restaurants and acclaimed theatre scene in this walkable area.

Union Square

Things to do

Golden Gate Bridge at night

San Francisco Night Tour

£39
per adult
78% of travellers recommend
San Francisco Night Tour
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

£28
per adult
94% of travellers recommend
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat
San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo

San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo

£21
per adult
94% of travellers recommend
San Francisco: Flyer Theater, 7D Ride & Laser Maze Combo
See all activities in San Francisco

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.