Title: £385 Cheap Flights from Lyon to San Francisco (LYS to SFO) - Expedia.co.uk ![Sunset view of the Golden Gate Bridge and fog from Battery Spencer, Golden Gate National Recreation Area, in San Francisco, California.](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £385 Cheap Flights from Lyon (LYS) to San Francisco (SFO) [View £385 flight on Thu, 19 Feb 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:LYS,to:SFO,departure:19/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:384.64&airProductToken=AQppCjMIwoIBEgMzNTcYi5YBIOuJASiDyIUDMPbIhQM4T0AAWAFqBU5PQkFHcglPTE41QzVCNFAKMgjCggESAzI4NxjriQEgsnEoncuFAzDF0IUDOE9AAVgBagVOT0JBR3IJT0xONUM1QjRQEgoIARABGAEqAkJBGAEiBAgBEAEoAigDMA0) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Saint-Exupery Airport (LYS) to San Francisco International Airport (SFO) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![Turkish Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TK.svg) Turkish Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Lufthansa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LH.svg) Lufthansa [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LH"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:lys,to:sfo,departure:03/10/2025TANYT&leg2=from:sfo,to:lys,departure:10/10/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ## Plan, book, fly with confidence - ### Be in the know Get alerts if flight prices drop or rise\* - ### Book smarter Save up to 25% on select hotels after you book a flight\* - ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Lyon (LYS) to San Francisco (SFO) Prices were available within the past 7 days and start at £385 for one-way flights and £432 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 19 Feb - Wed, 25 Feb LYS Lyon SFO San Francisco £432 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:19/02/2026TANYT&leg2=from:SFO,to:LYS,departure:25/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:431.10&airProductToken=AQprCjQI1KABEgM0NzMYi5YBIIuSASiQzIUDMKvNhQM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CCjMI1KABEgMyMzcYi5IBILJxKMPUhQMwxdqFAzhPQABYAWoHRElTQ0lOVHIIT0YwRFNJT0IKawozCNSgARIDMjM4GLJxIIuSASiDk4YDMJKYhgM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CCjQI1KABEgM0NzIYi5IBIIuWASiymYYDMMOahgM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Thu, 19 Feb - Wed, 25 Feb LYS Lyon SFO San Francisco £435 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:19/02/2026TANYT&leg2=from:SFO,to:LYS,departure:25/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:434.10&airProductToken=AQprCjQI1KABEgM0NzMYi5YBIIuSASiQzIUDMKvNhQM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CCjMI1KABEgMyMzcYi5IBILJxKMPUhQMwxdqFAzhPQABYAWoHRElTQ0lOVHIIT0YwRFNJT0IKawozCNSgARIDMjM4GLJxIIuSASiDk4YDMJKYhgM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CCjQI1KABEgM0NzAYi5IBIIuWASiaoYYDMKuihgM4T0AAWAFqB0RJU0NJTlRyCE9GMERTSU9CEgoIARABGAEqAlRQGAEiBAgBEAEoAigDKAQwDQ) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Thu, 19 Feb - Wed, 25 Feb LYS Lyon SFO San Francisco £436 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:19/02/2026TANYT&leg2=from:SFO,to:LYS,departure:25/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:435.34&airProductToken=AQpnCjIIwoIBEgMzNjEYi5YBIOuJASi4zIUDMKHNhQM4T0AAWAFqBU5PQkFHcghPTE43VDhCNAoxCMKCARIDMjg1GOuJASCycSjh1IUDMITahQM4T0ABWAFqBU5PQkFHcghPTE43VDhCNAqbAQoxCMKCARIENTYwNRiycSCpUSihkIYDMO2ShgM4T0AAWAFqBU5PQkFHcghPTE43VDhCNAoyCMKCARIEMTUxNRipUSDriQEoipSGAzCkl4YDOE9AAVgBagVOT0JBR3IIT0xON1Q4QjQKMgjCggESAzM1OBjriQEgi5YBKI2YhgMw9piGAzhPQAFYAWoFTk9CQUdyCE9MTjdUOEI0EgoIARABGAEqAkJBGAEiBAgBEAEoAigDMA0) ![TAP Portugal](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/TP.gif) Fri, 21 Nov - Fri, 28 Nov LYS Lyon SFO San Francisco £437 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:21/11/2025TANYT&leg2=from:SFO,to:LYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:436.70&airProductToken=AQptCjUI1KABEgM0NzEYi5YBIIuSASiY1P0CMLPV_QI4T0AAWAFqCERJU0NPVU5UcghPRjBEU0lPQgo0CNSgARIDMjM5GIuSASCycSiz3_0CMLXl_QI4T0ABWAFqCERJU0NPVU5UcghPRjBEU0lPQgptCjQI1KABEgMyMzgYsnEgi5IBKP6q_gIwl7D-AjhPQABYAWoIRElTQ09VTlRyCE9GMERTSU9CCjUI1KABEgM0NzAYi5IBIIuWASi7uP4CMMe5_gI4T0ABWAFqCERJU0NPVU5UcghPRjBEU0lPQhIKCAEQARgBKgJUUBgBIgQIARABKAIoAygEMAE) ![Aer Lingus](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/EI.gif) Fri, 21 Nov - Fri, 28 Nov LYS Lyon SFO San Francisco £439 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:21/11/2025TANYT&leg2=from:SFO,to:LYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:438.50&airProductToken=AQpWCioIxZIBEgM1NTMYi5YBIIMNKP7V_QIwhdf9AjhBQABYAXIIT0xOMFQwQjQKKAjFkgESAjYxGIMNILJxKM7g_QIw5-X9AjhPQAFYAXIIT0xOMFQwQjQKgwEKKgjFkgESBDcxMDIYsnEgrhwo9qz-AjD9rv4COE9AAFgBcghPTE4wVDBCNAopCMWSARIDMTIyGK4cIIMNKN6z_gIwlrf-AjhPQAFYAXIIT0xOMFQwQjQKKgjFkgESAzU1MhiDDSCLlgEo9Ln-AjD2uv4COEFAAVgBcghPTE4wVDBCNBIKCAEQARgBKgJFSRgBIgQIARABKAIoAygEMAE) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Sun, 23 Nov - Sat, 29 Nov LYS Lyon SFO San Francisco £440 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:23/11/2025TANYT&leg2=from:SFO,to:LYS,departure:29/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:439.74&airProductToken=AQqcAQoyCMKCARIDMzU3GIuWASDriQEouur9AjCt6_0COE9AAFgBagVOT0JBR3IIT0xON1Q4QjQKMgjCggESAzE5MxjriQEgo7EBKITt_QIw5vH9AjhPQAFYAWoFTk9CQUdyCE9MTjdUOEI0CjIIwoIBEgQ0MzU5GKOxASCycSjP8v0CML_0_QI4T0ABWAFqBU5PQkFHcghPTE43VDhCNAqdAQoyCMKCARIENjUwNxiycSCLuAEowrT-AjCetf4COE9AAFgBagVOT0JBR3IIT0xON1Q4QjQKMwjCggESBDE2MDQYi7gBIOuJASjJtf4CMMS6_gI4T0ABWAFqBU5PQkFHcghPTE43VDhCNAoyCMKCARIDMzYwGOuJASCLlgEovLv-AjClvP4COE9AAVgBagVOT0JBR3IIT0xON1Q4QjQSCggBEAEYASoCQkEYASIECAEQASgCKAMwDQ) ![Scandinavian Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/SK.gif) Sun, 23 Nov - Sat, 29 Nov LYS Lyon SFO San Francisco £442 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:23/11/2025TANYT&leg2=from:SFO,to:LYS,departure:29/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:441.70&airProductToken=AQpmCjII05YBEgQxNzk0GIuWASDiOyj-7v0CMPvv_QI4VEAAWAFqBUxJR0hUcghUTEVVNkdIVAowCNOWARIDOTM1GOI7ILJxKOH2_QIw6_v9AjhUQAFYAWoFTElHSFRyCFRMRVU2R0hUCmYKMAjTlgESAzkzNhiycSDiOyiItf4CMPS5_gI4VEAAWAFqBUxJR0hUcghUTEVVNkdIVAoyCNOWARIEMTc5MxjiOyCLlgEor7z-AjCxvf4COFRAAVgBagVMSUdIVHIIVExFVTZHSFQSCggBEAEYASoCU0sYASIECAEQASgCKAMoBDAB) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Fri, 21 Nov - Fri, 28 Nov LYS Lyon SFO San Francisco £449 Return found 6 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:21/11/2025TANYT&leg2=from:SFO,to:LYS,departure:28/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:448.74&airProductToken=AQqcAQoyCMKCARIDMzYzGIuWASDriQEo-tj9AjDj2f0COE9AAFgBagVOT0JBR3IIT0xOMFQwQlcKMgjCggESAzI4MxjriQEgi7gBKL3f_QIw6uT9AjhPQAFYAWoFTk9CQUdyCE9MTjBUMEJXCjIIwoIBEgQ0ODA5GIu4ASCycSi85v0CMJDn_QI4T0ABWAFqBU5PQkFHcghPTE4wVDBCVwpnCjEIwoIBEgMyODQYsnEg64kBKJqq_gIwkK_-AjhPQABYAWoFTk9CQUdyCE9MTjBUMEI0CjIIwoIBEgMzNjIY64kBIIuWASiHsv4CMPCy_gI4T0ABWAFqBU5PQkFHcghPTE4wVDBCNBIKCAIQARgCKgJCQRgBIgQIARABKAIoAygEMAE) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Thu, 19 Feb - Wed, 25 Feb LYS Lyon SFO San Francisco £466 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:19/02/2026TANYT&leg2=from:SFO,to:LYS,departure:25/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:465.44&airProductToken=AQqaAQoyCMKCARIDMzU5GIuWASDriQEozcqFAzC7y4UDOE9AAFgBagVOT0JBR3IIT0xON1Q4QlcKMQjCggESAzE3ORjriQEgqVEouMyFAzCd0IUDOE9AAVgBagVOT0JBR3IIT0xON1Q4QlcKMQjCggESBDQ3MTMYqVEgsnEotNSFAzDJ14UDOE9AAVgBagVOT0JBR3IIT0xON1Q4QlcKZwoxCMKCARIDMjg0GLJxIOuJASi6k4YDMLCYhgM4T0AAWAFqBU5PQkFHcghPTE43VDhCNAoyCMKCARIDMzYwGOuJASCLlgEo-JmGAzDhmoYDOE9AAVgBagVOT0JBR3IIT0xON1Q4QjQSCggCEAEYAioCQkEYASIECAEQASgCKAMoBDAB) ![Lufthansa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LH.gif) Sun, 23 Nov - Sat, 29 Nov LYS Lyon SFO San Francisco £501 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:LYS,to:SFO,departure:23/11/2025TANYT&leg2=from:SFO,to:LYS,departure:29/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:500.30&airProductToken=AQptCjUIzJABEgQxMDc3GIuWASClBCjD7P0CMJjt_QI4S0AAWAFqCEVDT0xJR0hUcghLTDZNUERCUQo0CMyQARIEOTQwOBilBCCycSjZ7f0CMJrz_QI4S0ABWAFqCEVDT0xJR0hUcghLTDZNUERCUQptCjQIzJABEgQ3OTk2GLJxIIwVKMqz_gIw8rj-AjhLQABYAWoIRUNPTElHSFRyCEtMNk1QREJRCjUIzJABEgQyMjQ4GIwVIIuWASi9uf4CMI26_gI4S0ABWAFqCEVDT0xJR0hUcghLTDZNUERCURIKCAIQARgCKgJMSBgBIgQIARABKAIoAygEMAs) ## Frequently asked questions ### How much is a flight from LYS to San Francisco Intl. Airport (SFO)? > Start packing your bags, because round-trip journeys from Saint-Exupery Airport (LYS) to San Francisco Airport start from £432. That's based on fares listed within the last 7 days on Expedia for flights departing within the next year. Prices can go up quickly, so book now to get the best deal. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Lyon Airport to SFO? > Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the easy instructions on our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from Lyon Airport to San Francisco Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for LYS to San Francisco Airport flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from Saint-Exupery Airport (LYS) to San Francisco Airport? > The distance is around 9,400 kilometres. Eye mask? Check. Noise-cancelling headphones? Double check. We suggest you pack all the essentials for this long-haul Colombier-Saugnieu to San Francisco flight. ### Which airlines fly direct from Lyon Airport to San Francisco Intl. Airport (SFO)? > Unfortunately, there aren't any airlines that fly direct between LYS and San Francisco Airport. You'll have to book a flight with at least one stop. ### Are Lyon Airport to San Francisco Intl. Airport (SFO) flight tickets cheaper when they're purchased at the last minute? > Airline tickets from Lyon Airport to SFO are available up to a year before departure on Expedia. And although you may occasionally pick up a fantastic last-minute deal, it's not something you should bank on. Also, booking your flights in advance means you'll have more choices — and you can avoid getting trapped in the dreaded middle seat! We regularly update our fares to bring you the best bargains, so check back often for all the latest specials. ## Travel information | Origin airport | Saint-Exupery | | --- | --- | | Destination airport | San Francisco Intl. | | Airlines serving | Aer Lingus, Air Canada, Air France, Austrian Airlines, British Airways, Brussels Airlines, Iberia, KLM, Lufthansa, Scandinavian Airlines, TAP Portugal, Turkish Airlines | | Return price | £431 | | Distance | 9310 km | ## Book with confidence ### Compare flights from Lyon to San Francisco easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Lyon to San Francisco. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to San Francisco Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Saint-Exupery to San Francisco Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Saint-Exupery (LYS) to San Francisco Intl. (SFO) The easiest way to view the best deals on flights from Lyon to San Francisco today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Saint-Exupery to San Francisco Intl. start at just £432 and range up to £515.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Lyon and San Francisco - booking your flight during February, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Lyon to San Francisco flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Saint-Exupery to San Francisco Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. 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