South San Francisco offers a unique blend of activities and experiences for discerning travellers seeking boutique accommodations. Start your exploration at the stunning waterfront park, where you can enjoy picturesque views of the bay and indulge in a leisurely stroll along the scenic paths, perfect for families and couples alike. For a taste of local culture, immerse yourself in the vibrant art scene by visiting nearby galleries that showcase the work of talented artists, providing a glimpse into the city’s creative spirit. Don't miss the opportunity to explore the charming neighborhoods filled with eclectic shops, where you can find one-of-a-kind souvenirs and artisanal goods. Food enthusiasts will delight in the diverse culinary options available, including innovative eateries that highlight fresh, locally-sourced ingredients. Lastly, take advantage of the nearby hiking trails that offer breathtaking panoramas of the surrounding landscapes, ideal for those looking for a bit of adventure. After a day of exploration, retreat to a boutique hotel where personalized service and attention to detail will ensure you feel pampered and well taken care of throughout your stay.

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Our top choices for South San Francisco boutique hotels

1. AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/WaterfrontOyster Point
9.2 out of 10, Wonderful, (1,001 reviews)
The price is £134
includes taxes & fees
28 Nov - 29 Nov

2. Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point AreaThe East Side
9.0 out of 10, Wonderful, (565 reviews)
The price is £95
includes taxes & fees
28 Nov - 29 Nov

3. Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport NorthThe East Side
9.0 out of 10, Wonderful, (1,288 reviews)
The price is £106
includes taxes & fees
14 Nov - 15 Nov

4. Airport Inn
Airport InnDowntown South San Francisco
9.0 out of 10, Wonderful, (1,001 reviews)
The price is £100
includes taxes & fees
7 Nov - 8 Nov

5. Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point WaterfrontOyster Point
8.8 out of 10, Excellent, (2,391 reviews)
The price is £87
includes taxes & fees
13 Nov - 14 Nov

6. Hotel Nova SFO
Hotel Nova SFOSouth San Francisco
8.8 out of 10, Excellent, (1,002 reviews)
The price is £109
includes taxes & fees
7 Nov - 8 Nov

7. Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster PointThe East Side
8.8 out of 10, Excellent, (1,840 reviews)
The price is £128
includes taxes & fees
5 Dec - 6 Dec

8. Hampton Inn San Francisco Airport
Hampton Inn San Francisco AirportThe East Side
8.8 out of 10, Excellent, (1,001 reviews)
The price is £100
includes taxes & fees
24 Nov - 25 Nov

9. Hilton Garden Inn San Francisco Arpt North
Hilton Garden Inn San Francisco Arpt NorthThe East Side
8.6 out of 10, Excellent, (1,001 reviews)
The price is £78
includes taxes & fees
23 Nov - 24 Nov

10. DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport BlvdSouth San Francisco
8.4 out of 10, Very good, (2,449 reviews)
The price is £91
includes taxes & fees
22 Nov - 23 Nov

11. Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport HotelSouth San Francisco
8.4 out of 10, Very good, (1,916 reviews)
The price is £101
includes taxes & fees
23 Nov - 24 Nov

12. Days Inn by Wyndham San Francisco S/Oyster Point Airport
Days Inn by Wyndham San Francisco S/Oyster Point AirportParadise Valley
8.4 out of 10, Very good, (116 reviews)
The price is £118
includes taxes & fees
8 Nov - 9 Nov

13. Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Sonesta ES Suites San Francisco Airport Oyster Point WaterfrontOyster Point
8.4 out of 10, Very good, (1,292 reviews)
The price is £132
includes taxes & fees
29 Nov - 30 Nov

14. Deluxe Inn
Deluxe InnSouth San Francisco
8.4 out of 10, Very good, (330 reviews)
The price is £100
includes taxes & fees
8 Nov - 9 Nov

15. La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport NDowntown South San Francisco
8.2 out of 10, Very good, (2,151 reviews)
The price is £93
includes taxes & fees
7 Nov - 8 Nov

16. Holiday Inn Express San Francisco-Airport North by IHG
Holiday Inn Express San Francisco-Airport North by IHGSouth San Francisco
8.2 out of 10, Very good, (1,002 reviews)
The price is £90
includes taxes & fees
8 Nov - 9 Nov

17. Americana Inn
Americana InnSouth San Francisco
8.0 out of 10, Very good, (339 reviews)
The price is £116
includes taxes & fees
6 Dec - 7 Dec

18. Four Points by Sheraton Hotel & Suites San Francisco Airport
Four Points by Sheraton Hotel & Suites San Francisco AirportSouth San Francisco
7.8 out of 10, Good, (1,003 reviews)
The price is £80
includes taxes & fees
22 Nov - 23 Nov

19. Hotel Focus SFO
Hotel Focus SFOThe East Side
7.6 out of 10, Good, (1,691 reviews)
The price is £73
includes taxes & fees
26 Nov - 27 Nov

20. Comfort Inn and Suites San Francisco Airport North
Comfort Inn and Suites San Francisco Airport NorthThe East Side
7.6 out of 10, Good, (999 reviews)
The price is £90
includes taxes & fees
5 Dec - 6 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about South San Francisco
Top South San Francisco Hotel Reviews

Parc 55 San Francisco - A Hilton Hotel
10/10 Excellent
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