An aerial view of San Francisco with the Golden Gate Bridge, hills, and the ocean.

Search Boutique Hotels in South San Francisco

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on South San Francisco Boutique Hotels

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for South San Francisco boutique hotels

An indoor swimming pool with arched ceilings and a reflection pool.
An architectural corridor with arches and columns, a window with a metal grille, and a view of a garden with a lamp post.
A library with bookshelves, a fireplace, and seating areas.
A courtyard with a stone bench, a table with chairs, and various potted plants.

1. Berkeley City Club

Berkeley City Club
Telegraph District
United States
Brett
£160
includes taxes & fees
11 Oct - 12 Oct
Berkeley City Club
A hotel courtyard with outdoor seating, a fire pit, and a vintage camper parked nearby.
A hotel room with a bed, a desk, a TV, and a view of the city.
A circular mirror reflecting a modern lounge area with sofas, a coffee table, and a vase with flowers.
A person reclining in a circular seating area with a plant and a colorful mural in the background.

2. Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
Fisherman's Wharf
United States
Jon
£168
includes taxes & fees
2 Nov - 3 Nov
Hotel Zephyr San Francisco
An outdoor cafe with brick walls, outdoor seating, and a tree in the foreground.
A spacious bar area with high wooden beams, a brick wall, and a variety of seating options including bar stools and tables.
A bar area with three black barstools, a wooden counter, and a shelf stocked with liquor bottles.
A hotel room with a brick wall, a bed with a tray of food, a lamp, and a view of the city through a window.

3. Argonaut Hotel

Argonaut Hotel
Fisherman's Wharf
United States
Richard
£240
includes taxes & fees
1 Nov - 2 Nov
Argonaut Hotel
A modern living room with a large window overlooking a bridge, a flat-screen TV, a clock, and a brown leather sofa.
A room with large windows overlooking a bridge and a body of water.
A cozy hotel lobby with a fireplace, two tables with teapots, and comfortable seating.
A group of people dining at a restaurant with a table set for a meal, including a bottle of wine and various dishes.

4. Harbor Court Hotel

Harbor Court Hotel
Downtown San Francisco
Canada
Yoojin
£210
includes taxes & fees
31 Oct - 1 Nov
Harbor Court Hotel
A spacious lobby with a staircase, comfortable seating areas, and large windows offering views of the city.
A modern building with a prominent entrance and a sign that reads "THE CLANCY".
An outdoor seating area with round tables and chairs, a fire feature, and string lights.
A modern cafe with a large window, white walls, and a variety of seating options including tables and a bench.

5. The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott
Downtown San Francisco
Canada
Samantha
£188
includes taxes & fees
30 Oct - 31 Oct
The Clancy, Autograph Collection by Marriott
A courtyard with a stone pathway, outdoor seating, and potted plants.
A modern interior with a large wooden panel wall, a reception desk, and a seating area with a small table and chairs.
A modern living room with a leather sofa, a wooden coffee table with books, a bookshelf, and a large window.
A spacious lounge area with leather chairs, a coffee table, and a bar in the background.

6. Hotel Kabuki, part of JdV by Hyatt

Hotel Kabuki, part of JdV by Hyatt
Western Addition
Canada
frank
£259
includes taxes & fees
25 Oct - 26 Oct
Hotel Kabuki, part of JdV by Hyatt
A hotel room with a bed, a nightstand with a lamp, a Gucci bag, a pizza, and a 'big little lies' shopping bag.
A multi-story hotel with a classic architectural design, featuring a prominent corner location with a street view.
A row of leather armchairs with checkered cushions in a lobby area.
A conference room with a long table, multiple chairs, a coffee station, a bookshelf, and a TV mounted on the wall.

7. Hotel Abri - Union Square

Hotel Abri - Union Square
Union Square
United States
Matthew
£133
includes taxes & fees
5 Nov - 6 Nov
Hotel Abri - Union Square
A modern hotel room with a grey sofa, a dining table, a TV, and a large window with curtains.
A modern hotel room with a dining area, a fireplace, a sofa set, and large windows offering city views.
A hotel room with a bed, a bathroom with a sink and mirror, and a view of the outside through the window.
A spacious hotel lobby with large windows, wooden beams, and a central bar area.

8. The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco
Union Square
United States
Randall Gray
£224
includes taxes & fees
16 Oct - 17 Oct
The Clift Royal Sonesta San Francisco
A modern bar area with a long wooden counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with a long table, multiple chairs, and a television screen displaying a fire.
A bar area with a bartender, wooden shelves with bottles, and bar stools.
A cozy reading nook with a stack of books, a teal sofa, and a floor lamp.

9. Hotel Emblem San Francisco

Hotel Emblem San Francisco
Union Square
United States
Keegan
£151
includes taxes & fees
1 Nov - 2 Nov
Hotel Emblem San Francisco
A grand lobby with high ceilings, chandeliers, and a fireplace.
A grand lobby with a large chandelier, a fireplace, and seating areas.
A hallway with a Christmas tree and nutcracker statues.
A grand lobby with a checkered floor, a blue sofa, and a chandelier.

10. The Marker Union Square San Francisco

The Marker Union Square San Francisco
Union Square
United States
Scott
£143
includes taxes & fees
6 Nov - 7 Nov
The Marker Union Square San Francisco
View all properties

Top South San Francisco Hotel Reviews

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

8/10 Good
"The only thing I didn’t like was the menu at the restaurant, not very much to choose from"
DAVID 1-night trip
Posted less than an hour ago
Hilton San Francisco Airport Bayfront
Handlery Union Square Hotel

Handlery Union Square Hotel

8/10 Good
"a"
Joseph 1-night trip
Posted 1 hour ago
Handlery Union Square Hotel
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent
"Very nice property close to Fisherman's Wharf"
David 2-night trip
Posted 10 hours ago
Hotel Riu Plaza Fisherman's Wharf
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

10/10 Excellent
"Good view very clean"
Alasdair 1-night trip
Posted 12 hours ago
Parc 55 San Francisco - A Hilton Hotel
Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

8/10 Good
"Convenient for access to SFO"
Eugene 1-night trip
Posted 17 hours ago
Travelodge by Wyndham San Francisco Airport North

Frequently asked questions

What's there to see and do in South San Francisco?
The shopping, restaurants and cafes are just some of the things to enjoy while you're in the area. While you're out and about in South San Francisco, popular attractions like San Francisco Bay, Chase Center and Oracle Park are worth a visit. You might also want to see spots like Pier 39, Santa Cruz Mountains and South San Francisco Hillside Sign during your trip.
What kind of weather should I plan for when I travel to South San Francisco?
Having a good idea of the weather in South San Francisco is important when planning your trip. The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.
What's the best way to get to my boutique hotel in South San Francisco?
You have a few options for travelling to and around South San Francisco. The closest major airport is San Francisco International Airport (SFO), which is located 2.9 mi (4.6 km) from the heart of the city, but Oakland, CA (OAK-Oakland Intl.) may also be an option. Head to South San Francisco Metro Station for metro travel. If you want to explore the larger area, hop on a train at South San Francisco Station.

Explore a world of travel with Expedia