Panama Luxury Holidays
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top flight + Luxury hotel deals in Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Reviewed on 2 Sept 2026
Hotel Casa Panamá
Reviewed on 2 Sept 2026
5* Luxury holidays in Panama
4 Night Luxury holidays in Panama
Hotel Casa Panamá
Reviewed on 2 Sept 2026
All you need to know about luxury holidays in Panama
What can I expect from a luxury Panama holiday?
Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.
How can I find all-inclusive luxury holidays in Panama?
Tick the all-inclusive and 5-star filters to find the crème de la crème of Panama holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.
Can I book a cheap luxury holiday to Panama?
A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Panama starting at £488. Prices and availability are subject to change. Additional terms may apply.
Are there luxury spa holidays in Panama?
For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Panama spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.
What should I look for when booking a luxury family holiday in Panama?
Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.
Can I book luxury last-minute holidays to Panama?
You can wangle a top-notch luxury holiday in Panama for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!
Can I book a luxury holiday in Panama with free cancellation and/or flexible dates?
If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.
Why should I book my luxury travel to Panama with Expedia?
Nobody does luxury quite like Expedia. With so many gorgeous properties in Panama to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.
Top Luxury Panama Hotels
JW Marriott Panama
- 7 min drive from Albrook Shopping Mall
Bristol Panama, a Registry Collection Hotel
- 4 min drive from Albrook Shopping Mall
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Reviewed on 28 Aug 2026
Waldorf Astoria Panama
- 4 min drive from Albrook Shopping Mall
Things to do
Half day of Panama city and canal tour: shared and private
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama City Visit an Indian town Embera and waterfall with lunch
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
