Luxury Sicily Holidays & Travel

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    Save up to £750 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Packages with flights are ATOL protected

Top flight + Luxury hotel deals in Sicily

Price found within the past 48 hours. Click for updated prices.
Hotel Tritone

Hotel Tritone

£518
per person
3 Oct - 7 Oct
found 1 day ago
Return direct flight included
London (LHR) to Catania (CTA)
9.2/10 Wonderful! (103 reviews)
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£838
per person
28 Sept - 2 Oct
found 1 day ago
Return flight included
Edinburgh (EDI) to Palermo (PMO)
8.4/10 Very good! (1,000 reviews)
Very large variety of food items in breakfast. It was thoroughly worth purchasing the breakfast option with the room.

Reviewed on 24 Aug 2026

Hotel Metropole Taormina

Hotel Metropole Taormina

Taormina City Centre
Save 100% on your flight
£2,916
per person
24 Sept - 27 Sept
just found
Return flight included
London (LON) to Catania (CTA)
9.4/10 Exceptional! (277 reviews)
Amazing

Reviewed on 12 Jul 2026

The Ashbee Hotel - The Leading Hotels of the World

The Ashbee Hotel - The Leading Hotels of the World

Save 100% on your flight
£2,021
per person
25 Oct - 27 Oct
found 1 day ago
Return flight included
London (LON) to Catania (CTA)
9.2/10 Wonderful! (145 reviews)
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£845
per person
29 Oct - 1 Nov
found 1 day ago
Return flight included
London (LGW) to Palermo (PMO)
8.4/10 Very good! (1,004 reviews)
Bautiful old stayle Italian gradious hotel, incredible service, welcoming, warm and polite staff doing beyond expected to help and support. Highly recommended!

Reviewed on 20 Aug 2026

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5* Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£845
per person
29 Oct - 1 Nov
found 1 day ago
Return flight included
London (LGW) to Palermo (PMO)
8.4/10 Very good! (1,004 reviews)
Bautiful old stayle Italian gradious hotel, incredible service, welcoming, warm and polite staff doing beyond expected to help and support. Highly recommended!

Reviewed on 20 Aug 2026

Hotel Metropole Taormina

Hotel Metropole Taormina

Taormina City Centre
Save 100% on your flight
£2,916
per person
24 Sept - 27 Sept
just found
Return flight included
London (LON) to Catania (CTA)
9.4/10 Exceptional! (277 reviews)
Amazing

Reviewed on 12 Jul 2026

The Ashbee Hotel - The Leading Hotels of the World

The Ashbee Hotel - The Leading Hotels of the World

Save 100% on your flight
£2,021
per person
25 Oct - 27 Oct
found 1 day ago
Return flight included
London (LON) to Catania (CTA)
9.2/10 Wonderful! (145 reviews)
Don't see what you're looking for?
See all available trips from London to Sicily
View all trips

3 Night Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£491
per person
21 Oct - 24 Oct
found 1 day ago
Return direct flight included
London (LGW) to Palermo (PMO)
8.4/10 Very good! (1,000 reviews)
Very large variety of food items in breakfast. It was thoroughly worth purchasing the breakfast option with the room.

Reviewed on 24 Aug 2026

Hotel Metropole Taormina

Hotel Metropole Taormina

Taormina City Centre
Save 100% on your flight
£2,916
per person
24 Sept - 27 Sept
just found
Return flight included
London (LON) to Catania (CTA)
9.4/10 Exceptional! (277 reviews)
Amazing

Reviewed on 12 Jul 2026

The Ashbee Hotel - The Leading Hotels of the World

The Ashbee Hotel - The Leading Hotels of the World

Save 100% on your flight
£2,891
per person
25 Oct - 28 Oct
found 1 day ago
Return flight included
London (LON) to Catania (CTA)
9.2/10 Wonderful! (145 reviews)
Don't see what you're looking for?
See all available trips from London to Sicily
View all trips

4 Night Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Hotel Tritone

Hotel Tritone

£518
per person
3 Oct - 7 Oct
found 1 day ago
Return direct flight included
London (LHR) to Catania (CTA)
9.2/10 Wonderful! (103 reviews)
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£838
per person
28 Sept - 2 Oct
found 1 day ago
Return flight included
Edinburgh (EDI) to Palermo (PMO)
8.4/10 Very good! (1,000 reviews)
Very large variety of food items in breakfast. It was thoroughly worth purchasing the breakfast option with the room.

Reviewed on 24 Aug 2026

Hotel Metropole Taormina

Hotel Metropole Taormina

Taormina City Centre
£2,448
per person
28 Sept - 2 Oct
found 14 hours ago
Return flight included
Bristol (BRS) to Catania (CTA)
9.4/10 Exceptional! (277 reviews)
Amazing

Reviewed on 12 Jul 2026

Don't see what you're looking for?
See all available trips from London to Sicily
View all trips

All you need to know about luxury holidays in Sicily

What can I expect from a luxury Sicily holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in Sicily?

Tick the all-inclusive and 5-star filters to find the crème de la crème of Sicily holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to Sicily?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Sicily starting at £491. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in Sicily?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Sicily spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in Sicily?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to Sicily?

You can wangle a top-notch luxury holiday in Sicily for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in Sicily with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to Sicily with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in Sicily to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury Sicily Hotels

San Domenico Palace, Taormina, A Four Seasons Hotel

San Domenico Palace, Taormina, A Four Seasons Hotel

PIAZZA SAN DOMENICO, 5 Taormina ME
  • 5 hours drive from Mondello Beach
£2,240
per night
28 Aug - 29 Aug
Stay at this luxury hotel in Taormina. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the property condition in their reviews. Popular ...
9.4/10 Exceptional! (303 reviews)
"This was one of the best experiences we’ve had, and really appreciate the staff at this beautiful hotel. The space is lovely, as are the rooms. The location is incredible and the views can’t be beat. Finally, the team there were so helpful and genuinely invested in our comfort. They went way out ..."

Reviewed on 23 Aug 2026

San Domenico Palace, Taormina, A Four Seasons Hotel
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR
  • 6 hours drive from Mondello Beach
£504
per night
5 Sept - 6 Sept
Stay at this luxury hotel in Syracuse. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Popular attractions Tropical Aquarium of Syracuse and Fonte Aretusa ...
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR
  • 6 hours drive from Mondello Beach
£272
per night
28 Aug - 29 Aug
Stay at this luxury hotel in Syracuse. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (619 reviews)
"The private beach and the breakfast/terrace make this hotel 5*****. The hotel is badly in need of updating/renovating. Old stained carpets and stodgy furniture and curtains. They could definitely keep all the old world charm with a fresh look. However, the staff is incredible and keeps the hotel ..."

Reviewed on 24 Aug 2026

Grand Hotel Ortigia Siracusa
See all 28,184 properties in Sicily
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

City Sightseeing Palermo Hop-on Hop-off Bus Tour

City Sightseeing Palermo Hop-on Hop-off Bus Tour

£13
per adult
City Sightseeing Palermo Hop-on Hop-off Bus Tour
Syracuse: Ortigia Island and Sea Caves Boat Tour

Syracuse: Ortigia Island and Sea Caves Boat Tour

£256
per traveller
Syracuse: Ortigia Island and Sea Caves Boat Tour
Segesta, Erice and Salt Pans Full-Day Excursion from Palermo

Segesta, Erice and Salt Pans Full-Day Excursion from Palermo

£60
per adult
88% of travellers recommend
Segesta, Erice and Salt Pans Full-Day Excursion from Palermo
See all activities in Sicily

More holidays you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.