Luxury Sicily Holidays & Travel

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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Packages with flights are ATOL protected

Top flight + Luxury hotel deals in Sicily

Price found within the past 48 hours. Click for updated prices.
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£262
per person
10 Nov - 13 Nov
found 1 day ago
Return flight included
London (STN) to Palermo (PMO)
8.4/10 Very good! (1,004 reviews)
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£813
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
8.4/10 Very good! (1,002 reviews)
Villa Athena Resort

Villa Athena Resort

£737
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
9.4/10 Exceptional! (834 reviews)
The Villa Athena is an amazing luxury hotel with an amazing location. With a direct view of Greek temples, as well as private access, sets this property apart from others. In addition the rooms are well appointed and comfortable. We also enjoyed our private balcony with direct access to the property and pool area. The staff was welcoming and attentive. I like the size of the resort as it feels more intimate and personalized. We also took advantage of the amazing restaurant as well. We will definitely return for another stay in the future.

Reviewed on 14 Sept 2026

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Ortigia
£602
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Catania (CTA)
9.6/10 Exceptional! (1,005 reviews)
It's a cute and cosy hotel right next to the ocean. Gorgeous views day and night. Breakfast was very impressive and with lots of varieties to choose. I enjoyed the breakfast a lot. Not sure about the rest of the hotel, the room I stayed, the shower needed some maintenance work. The draining was slow and the doors couldn't closed with complete seal so the water goes out. Be prepared for the small size of the single room, but it was enough for me, especially when I didn't stay in the room during the day. Staff friendliness was mixed. Some were extremely friendly, some were not helpful, but would say 90% of the staff were very friendly, kind, respectful, and willing to help.

Reviewed on 8 Oct 2026

Rocco Forte Villa Igiea

Rocco Forte Villa Igiea

Monte Pellegrino
Save 100% on your flight
£1,308
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
9.6/10 Exceptional! (131 reviews)
Beautiful hotel and grounds. It’s pricey but had a wonderful stay

Reviewed on 9 Oct 2026

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5* Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Villa Athena Resort

Villa Athena Resort

£737
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
9.4/10 Exceptional! (834 reviews)
The Villa Athena is an amazing luxury hotel with an amazing location. With a direct view of Greek temples, as well as private access, sets this property apart from others. In addition the rooms are well appointed and comfortable. We also enjoyed our private balcony with direct access to the property and pool area. The staff was welcoming and attentive. I like the size of the resort as it feels more intimate and personalized. We also took advantage of the amazing restaurant as well. We will definitely return for another stay in the future.

Reviewed on 14 Sept 2026

Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£813
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
8.4/10 Very good! (1,002 reviews)
Rocco Forte Villa Igiea

Rocco Forte Villa Igiea

Monte Pellegrino
Save 100% on your flight
£1,308
per person
12 Dec - 18 Dec
found 1 day ago
Return direct flight included
London (LHR) to Palermo (PMO)
9.6/10 Exceptional! (131 reviews)
Beautiful hotel and grounds. It’s pricey but had a wonderful stay

Reviewed on 9 Oct 2026

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3 Night Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£262
per person
10 Nov - 13 Nov
found 1 day ago
Return flight included
London (STN) to Palermo (PMO)
8.4/10 Very good! (1,004 reviews)
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£1,281
per person
10 Nov - 13 Nov
found 1 day ago
Return flight included
London (STN) to Palermo (PMO)
8.4/10 Very good! (1,002 reviews)
Le Calette N°5

Le Calette N°5

£906
per person
24 Nov - 27 Nov
found 22 hours ago
Return flight included
Edinburgh (EDI) to Palermo (PMO)
9.6/10 Exceptional! (230 reviews)
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4 Night Luxury holidays in Sicily

Price found within the past 48 hours. Click for updated prices.
Eurostars Centrale Palace

Eurostars Centrale Palace

Palermo Historical Center
Save 100% on your flight
£346
per person
12 Nov - 16 Nov
just found
Return flight included
London (LON) to Palermo (PMO)
8.4/10 Very good! (1,004 reviews)
Grand Hotel et Des Palmes

Grand Hotel et Des Palmes

Politeama
Save 100% on your flight
£948
per person
12 Nov - 16 Nov
just found
Return flight included
London (LON) to Palermo (PMO)
8.4/10 Very good! (1,002 reviews)
Villa Athena Resort

Villa Athena Resort

£1,172
per person
27 Dec - 31 Dec
found 17 hours ago
Return direct flight included
London (LHR) to Palermo (PMO)
9.4/10 Exceptional! (834 reviews)
The Villa Athena is an amazing luxury hotel with an amazing location. With a direct view of Greek temples, as well as private access, sets this property apart from others. In addition the rooms are well appointed and comfortable. We also enjoyed our private balcony with direct access to the property and pool area. The staff was welcoming and attentive. I like the size of the resort as it feels more intimate and personalized. We also took advantage of the amazing restaurant as well. We will definitely return for another stay in the future.

Reviewed on 14 Sept 2026

Don't see what you're looking for?
See all available trips from London to Sicily
View all trips

All you need to know about luxury holidays in Sicily

What can I expect from a luxury Sicily holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in Sicily?

Tick the all-inclusive and 5-star filters to find the crème de la crème of Sicily holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to Sicily?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Sicily starting at £262. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in Sicily?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Sicily spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in Sicily?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to Sicily?

You can wangle a top-notch luxury holiday in Sicily for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in Sicily with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to Sicily with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in Sicily to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury Sicily Hotels

San Domenico Palace, Taormina, A Four Seasons Hotel

San Domenico Palace, Taormina, A Four Seasons Hotel

PIAZZA SAN DOMENICO, 5 Taormina ME
  • 5 hours drive from Mondello Beach
£1,261
2 Nov - 3 Nov
includes taxes & fees
Stay at this luxury hotel in Taormina. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the property condition in their reviews. Popular ...
San Domenico Palace, Taormina, A Four Seasons Hotel
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR
  • 6 hours drive from Mondello Beach
£516
15 Oct - 16 Oct
includes taxes & fees
Stay at this luxury hotel in Syracuse. Enjoy free breakfast, free Wi-Fi and an outdoor pool. Popular attractions Tropical Aquarium of Syracuse and Fonte Aretusa ...
Grand Hotel Des Ètrangers - The Leading Hotels of the World
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR
  • 6 hours drive from Mondello Beach
£242
8 Nov - 9 Nov
includes taxes & fees
Stay at this luxury hotel in Syracuse. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (634 reviews)
"Very clean hotel! Great location walking into town. Parking was very convenient. Worth it to stay after you in the car. Staff was very kind."

Reviewed on 9 Oct 2026

Grand Hotel Ortigia Siracusa
See all 28,209 properties in Sicily
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

City Sightseeing Palermo Hop-on Hop-off Bus Tour

City Sightseeing Palermo Hop-on Hop-off Bus Tour

£13
per adult
City Sightseeing Palermo Hop-on Hop-off Bus Tour
Syracuse: Ortigia Island and Sea Caves Boat Tour

Syracuse: Ortigia Island and Sea Caves Boat Tour

£17
per adult
Syracuse: Ortigia Island and Sea Caves Boat Tour
Picture 1 for Activity Catania: Etna Morning Excursion with Tasting and Pickup

Catania: Etna Morning Excursion with Tasting and Pickup

£46
per adult
100% of travellers recommend
Catania: Etna Morning Excursion with Tasting and Pickup
See all activities in Sicily

More holidays you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.