Title: TOP Boutique Hotels in Tenderloin, CA for 2026 | Expedia.co.uk [Tenderloin Travel Guide](https://expedia.co.uk/San-Francisco-Tenderloin.dx6203136)[Holiday Rentals in San Francisco](https://expedia.co.uk/San-Francisco-Holiday-Rentals.d178305.Travel-Guide-HolidayRentals)[Flights to San Francisco](https://expedia.co.uk/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.co.uk/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Tenderloin Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Tenderloin.d6203136.Car-Hire-Guide)[Tenderloin Holidays](https://expedia.co.uk/Tenderloin.d6203136.Holidays-City-Breaks) ![SanFrancisco_Tenderloin_6203136_5](https://images.trvl-media.com/place/6203136/7e4cdb86-4a34-4b4f-b261-0e9bed5cb2ba.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6203136/7e4cdb86-4a34-4b4f-b261-0e9bed5cb2ba.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tenderloin Boutique Hotels Tonight [13 Feb - 14 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-02-13&endDate=2026-02-14&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [14 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-02-14&endDate=2026-02-15&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-02-20&endDate=2026-02-22&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Tenderloin boutique hotels ![Property grounds](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/78023bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/5bd0b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/246bb663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/cb9fb20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Berkeley City Club [](https://www.expedia.co.uk/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) Telegraph District 8.8/10 Excellent (701 reviews) "Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter [](https://www.expedia.co.uk/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/e1f91bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/568efffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/2d47f36f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/7158d83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Argonaut Hotel [](https://www.expedia.co.uk/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) Fisherman's Wharf 9.4/10 Exceptional (1,239 reviews) "The stay was very nice and the food was good as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harry £237 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/173b8dfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/19abbe84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/4817709a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zephyr San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) Fisherman's Wharf 8.6/10 Excellent (2,437 reviews) "Great location on the wharf, with many restaurants, and activities in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank £145 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1890000/1886700/1886656/210c1f9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1890000/1886700/1886656/cd0d8c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1890000/1886700/1886656/06b8ed26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1890000/1886700/1886656/a9ed4837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cavallo Point [](https://www.expedia.co.uk/Sausalito-Hotels-Cavallo-Point.h1886656.Hotel-Information) Sausalito 9.2/10 Wonderful (996 reviews) "Fantastic place! Coming back in a month." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Béatrice £428 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/Sausalito-Hotels-Cavallo-Point.h1886656.Hotel-Information) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/700/660/27f19182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/700/660/1d0c1fa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/700/660/7ebf7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/700/660/87dba6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Emblem San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Emblem-San-Francisco.h660.Hotel-Information) Union Square 9.4/10 Exceptional (1,001 reviews) "Clean room, fun amenities, personal service, we love staying here!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne £156 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Emblem-San-Francisco.h660.Hotel-Information) ![Suite (Skyline Waterfront Penthouse) | View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/1b7910ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/1000000/10000/400/384/a04417ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/400/384/df9b3b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/384/6dda3257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor Court Hotel [](https://www.expedia.co.uk/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1,003 reviews) "Beautifully remodeled, convenient, great staff. Room was nicely furnished and comfortable bed. Would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Analea £139 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/1656ff5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/100ffc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/da0bd574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1,000 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey £165 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/4ff57257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d5b628f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Campton) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/0d62a8a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/355c4c16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Taj Campton Place [](https://www.expedia.co.uk/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Union Square 9.2/10 Wonderful (1,000 reviews) "It was a perfect stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Travel To Explore £179 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/900/864/25ea6e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/9c354d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/10000/900/864/8b2202a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/10000/900/864/167bd1f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Huntington Hotel [](https://www.expedia.co.uk/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) Downtown San Francisco £728 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/San-Francisco-Hotels-Huntington-Hotel.h864.Hotel-Information) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/1600/1511/dd6a8571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/1600/1511/a0e2014a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/10000/1600/1511/1c71b5a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/1600/1511/badb47f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn At Union Square [](https://www.expedia.co.uk/San-Francisco-Hotels-Inn-At-Union-Square.h1511.Hotel-Information) Union Square 9.2/10 Wonderful (1,003 reviews) "The breakfast was fresh and good and internal amenities are very comfortable" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramesh Murthy £111 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/San-Francisco-Hotels-Inn-At-Union-Square.h1511.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-28&endDate=2026-03-01®ionId=6203136&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Tenderloin Hotel Reviews ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Excellent! We highly recommend the Hotel. " [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Bay Landing San Francisco Airport Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1110800/1110785/0c231d9b_y.jpg) ### Bay Landing San Francisco Airport Hotel 10/10 Excellent "Location " [](https://expedia.co.uk/San-Francisco-Hotels-Bay-Landing-San-Francisco-Airport-Hotel.h1110785.Hotel-Information) ![Hotel Zoe Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87_y.jpg) ### Hotel Zoe Fisherman's Wharf 10/10 Excellent "We had an amazing time at the hotel. The staff were great and ready to help. Anything we were needing was addressed quickly, even during Super Bowl weekend. I was expecting lag at some point but was very pleasantly surprised it was all smooth sailing. Extra kudos to Ben for making our stay a very enjoyable and personal experience. The hotel is a couple easy blocks from the Warf so it was very convenient. Make sure the enjoy the outdoor fire pits if you decide on a night in." [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Great location. Small, but comfortable rooms. Free coffee and cookies every morning. No AC, (windows open) but didn’t need it. SF is cool in Feb. Would definitely recommend." [](https://expedia.co.uk/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Hilton San Francisco Union Square](https://images.trvl-media.com/lodging/1000000/30000/25700/25622/e6c58ddf_y.jpg) ### Hilton San Francisco Union Square 10/10 Excellent "Yes very clean" [](https://expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Union-Square.h25622.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Spacious rooms and the pool is special. Excellent location in the city. I would recommend and stay again. Feels very safe." [](https://expedia.co.uk/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "Staff were amazing and room very comfortable. " [](https://expedia.co.uk/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![Hotel Zephyr San Francisco](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170_y.jpg) ### Hotel Zephyr San Francisco 10/10 Excellent "clean, convenient loacation" [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Hotel Nikko San Francisco](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12_y.jpg) ### Hotel Nikko San Francisco 10/10 Excellent "Great location, nice room. Clean." [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information) ## Frequently asked questions ### What's there to see and do in Tenderloin? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Adults Only Resorts & in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Adults-Only-Resorts.0-0-d6056043-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Green Hotels in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Green-Sustainable.0-0-d6056043-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Hotel-With-A-Bar.0-0-d6056043-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with Babysitting Services in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Hotel-With-Babysitting-Services.0-0-d6056043-thotelwithbabysittingservices.Travel-Guide-Filter-Hotels) - [Hotels with Breakfast in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Hotel-With-Breakfast.0-0-d6056043-thotelwithbreakfast.Travel-Guide-Filter-Hotels) - 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