Title: TOP Boutique Hotels in Tenderloin, CA for 2026 | Expedia.co.uk [Tenderloin Travel Guide](https://expedia.co.uk/San-Francisco-Tenderloin.dx6203136)[Holiday Rentals in San Francisco](https://expedia.co.uk/San-Francisco-Holiday-Rentals.d178305.Travel-Guide-HolidayRentals)[Flights to San Francisco](https://expedia.co.uk/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.co.uk/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Tenderloin Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Tenderloin.d6203136.Car-Hire-Guide)[Tenderloin Holidays](https://expedia.co.uk/Tenderloin.d6203136.Holidays-City-Breaks) ![SanFrancisco_Tenderloin_6203136_5](https://images.trvl-media.com/place/6203136/7e4cdb86-4a34-4b4f-b261-0e9bed5cb2ba.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Tenderloin - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tenderloin Boutique Hotels Tonight [30 Dec - 31 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2025-12-30&endDate=2025-12-31&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [31 Dec - 1 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2025-12-31&endDate=2026-01-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6203136&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Tenderloin boutique hotels ![Games room](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/d2ac54ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/a3393d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fecca267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zephyr San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) Fisherman's Wharf 8.6/10 Excellent (2342) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah £135 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/5bd0b8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/cb9fb20d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/4da6aa13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1180000/1175900/1175858/78023bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Berkeley City Club [](https://www.expedia.co.uk/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) Telegraph District 8.8/10 Excellent (697) "Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter [](https://www.expedia.co.uk/Oakland-Hotels-Berkeley-City-Club.h1175858.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/39d3931a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/2d47f36f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/49fa748f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/920000/915600/915510/7158d83b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Argonaut Hotel [](https://www.expedia.co.uk/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) Fisherman's Wharf 9.4/10 Exceptional (1216) "Absolutely amazing hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alicia £172 includes taxes & fees 26 Jan - 27 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Argonaut-Hotel-A-Noble-House-Hotel.h915510.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/5023ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/c438fd26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/03417113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) Downtown San Francisco 9.2/10 Wonderful (1001) "Very professional staff! Central located walking distance to everything!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edmundo £174 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7626c0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/174738f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/c731c06a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/21100/21073/7c771a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clift Royal Sonesta San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) Union Square 9.2/10 Wonderful (1370) "clean, well appointed room in a good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susanna £146 includes taxes & fees 17 Jan - 18 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Clift-Royal-Sonesta-San-Francisco.h21073.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/876/bf356ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, hypo-allergenic bedding, down duvets, minibar](https://images.trvl-media.com/lodging/1000000/10000/900/876/w3837h2560x3y0-673688de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/900/876/ef0e2e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/876/e25769c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Warwick San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) Union Square 8.2/10 Very good (1003) "Room was very nice! Staff was wonderful! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian £118 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Warwick-San-Francisco.h876.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/a6ba3784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/11530a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/f8220459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/15800/15769/33ce2394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marker Union Square San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) Union Square 9.0/10 Wonderful (1132) "The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith £122 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-The-Marker-San-Francisco.h15769.Hotel-Information) ![Suite, Multiple Beds (The Two Bedroom) | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/bf019538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/9fb30810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/b513dbea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/49800/49777/6d934a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Francisco [](https://www.expedia.co.uk/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) Union Square 8.4/10 Very good (632) "Great vibe here and the rooms and so cute . Excellent bar and bar staff . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana £93 includes taxes & fees 15 Jan - 16 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Palihotel-San-Francisco.h49777.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/631bdce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/10000/400/384/df9b3b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Skyline Waterfront Penthouse) | View from room](https://images.trvl-media.com/lodging/1000000/10000/400/384/1b7910ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/384/8bc35411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harbor Court Hotel [](https://www.expedia.co.uk/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) Downtown San Francisco 9.0/10 Wonderful (1005) "Great location, vintage place & walkable everywhere" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBERT £155 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Harbor-Court-Hotel.h384.Hotel-Information) ![City view](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d044cc49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/67a43361.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/d5b628f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/23400/23383/111bcf12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Taj Campton Place [](https://www.expedia.co.uk/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Union Square 9.2/10 Wonderful (1000) "Wonderful Staff and hospitality." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel £181 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Francisco-Hotels-Taj-Campton-Place.h23383.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-13&endDate=2026-01-14®ionId=6203136&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Tenderloin Hotel Reviews ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Excellent service and comfort." [](https://expedia.co.uk/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg) ### Hotel Riu Plaza Fisherman's Wharf 10/10 Excellent "Food is good and staff friendly " [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Riu-Plaza-Fishermans-Wharf.h24625.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Everything was perfect and beautiful " [](https://expedia.co.uk/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Hotel Zoe Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/10000/3600/3552/21cb8d87_y.jpg) ### Hotel Zoe Fisherman's Wharf 10/10 Excellent "Location, facilities, and staff were great. Highly recommend. We would return!" [](https://expedia.co.uk/San-Francisco-Hotels-Hotel-Zoe-Fishermans-Wharf.h3552.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "Very nice and clearn" [](https://expedia.co.uk/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ![The Westin St. Francis San Francisco on Union Square](https://images.trvl-media.com/lodging/1000000/30000/26800/26760/99dd32f8_y.jpg) ### The Westin St. Francis San Francisco on Union Square 10/10 Excellent "Clean room, friendly staff, free water, and available room service " [](https://expedia.co.uk/San-Francisco-Hotels-The-Westin-St-Francis-San-Francisco-On-Union-Square.h26760.Hotel-Information) ![Hilton San Francisco Airport Bayfront](https://images.trvl-media.com/lodging/1000000/20000/12400/12345/7b6b8635_y.jpg) ### Hilton San Francisco Airport Bayfront 10/10 Excellent "Very attentive and professional staff." [](https://expedia.co.uk/San-Francisco-Hotels-Hilton-San-Francisco-Airport-Bayfront.h12345.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "The hotel was a bit dated, but the staff were excellent. The room was comfortable. I especially want to thank Ms Rina Salangad and Sheila Curameng for their superb service. Overall, I had a good experience at this hotel. " [](https://expedia.co.uk/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "Good ratio of price and quality " [](https://expedia.co.uk/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ## Frequently asked questions ### What's there to see and do in Tenderloin? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Adults Only Resorts & in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Adults-Only-Resorts.0-0-d6056043-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Green Hotels in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Green-Sustainable.0-0-d6056043-tGreenSustainable.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Bay Area ](https://www.expedia.co.uk/Bay-Area-Hotels-Hotel-With-A-Bar.0-0-d6056043-thotelwithabar.Travel-Guide-Filter-Hotels) - 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