Title: Mission District Travel Guide: Best of Mission District, San Francisco Travel 2026 | Expedia.co.uk [Hotels in Mission District](https://expedia.co.uk/Mission-District-San-Francisco-Hotels.0-n134035-0.Travel-Guide-Filter-Hotels)[Flights to San Francisco](https://expedia.co.uk/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.co.uk/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Mission District Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-District.d134035.Car-Hire-Guide)[Mission District Holidays](https://expedia.co.uk/Mission-District.d134035.Holidays-City-Breaks) # Mission District Travel Guide ## San Francisco ![Mission District which includes outdoor art](https://images.trvl-media.com/place/134035/1fb7195b-23e3-4a0f-a5ef-22b484069f64.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mission District which includes outdoor art](https://images.trvl-media.com/place/134035/1fb7195b-23e3-4a0f-a5ef-22b484069f64.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mission District featuring street scenes](https://images.trvl-media.com/place/134035/a7dd2ce0-c9ce-486a-b651-24b57ca93ce3.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Balmy Alley showing outdoor art](https://images.trvl-media.com/place/6155695/560d514f-9293-427e-9e42-edb491a40ec5.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mission District](https://images.trvl-media.com/place/134035/9b55bf62-9d93-4944-8e5c-a68f70b2045b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Mission District Things to do Hotels Where to stay [San Francisco travel guide](https://expedia.co.uk/San-Francisco.dx178305) --- ### Popular places to visit ![Mission Dolores Park showing picnicing and a park as well as a small group of people](https://images.trvl-media.com/place/6227863/25b08d00-dd62-481f-96d0-2435525b2d69.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mission Dolores Park Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area. [](https://expedia.co.uk/Mission-Dolores-Park-Mission-District.d6227863.Attraction) ![Balmy Alley which includes outdoor art](https://images.trvl-media.com/place/6155695/91b2c10f-db02-4b62-b305-5d13d530f8d1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Balmy Alley Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the acclaimed art galleries and fascinating museums in this vibrant area. [](https://expedia.co.uk/Balmy-Alley-Mission-District.d6155695.Attraction) ![Mission San Francisco de Asís was founded 29 June 1776 by Padre Francisco Palóu and Padre Pedro Benito Cambón. The mission is named for Saint Francis of Assisi. The current site was picked in 1782 because of the harsh conditions at the original mission. It is considered to be the oldest intact building in San Francisco. The Mission is located in the San Francisco Mission District at the corner of 16th and Dolores Streets. #Details #golden #troveontuesday #Trovember](https://images.trvl-media.com/place/3132/09ecbd65-c360-4deb-a33d-1c6d359854ab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mission San Francisco de Asís Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area. [](https://expedia.co.uk/Mission-San-Francisco-De-Asis-San-Francisco.d553248634285122123.Attraction) #### Zuckerberg San Francisco General Hospital & Trauma Center If Zuckerberg San Francisco General Hospital & Trauma Center is what brings you to town, hopefully you'll have a chance to explore more of San Francisco. [](https://expedia.co.uk/Zuckerberg-San-Francisco-General-Hospital-Trauma-Center-San-Francisco.d624556062748250112.Attraction) #### UCSF at San Francisco General Hospital If UCSF at San Francisco General Hospital is what brings you to town, hopefully you'll have a chance to explore more of San Francisco. [](https://expedia.co.uk/UCSF-At-San-Francisco-General-Hospital-Mission-District.d624552609418383360.Attraction) #### SF Armory You can learn about the history of San Francisco with a stop at SF Armory. Experience the fascinating museums and acclaimed theatre scene in this vibrant area. [](https://expedia.co.uk/SF-Armory-San-Francisco.d553248621555612156.Attraction) ### Things to do ![California Academy of Sciences General Admission](https://mediaim.expedia.com/localexpert/219652/f0bca80b-682f-4287-bac0-eccb47dd5591.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### California Academy of Sciences Daytime Admission £37 per adult **86%** of travellers recommend [](https://expedia.co.uk/things-to-do/california-academy-of-sciences-daytime-admission.a219652.activity-details) ![San Francisco City Lights Cruise](https://mediaim.expedia.com/localexpert/219776/95f2a2ad-387b-435e-99b1-49a9d049006c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Francisco City Lights Cruise (2-hours) £43 per adult **94%** of travellers recommend [](https://expedia.co.uk/things-to-do/san-francisco-city-lights-cruise-2-hours.a219776.activity-details) ![Go City: San Francisco All-Inclusive Pass with 25+ Attractions](https://mediaim.expedia.com/localexpert/219896/8f48853e-8b87-4e6b-85c2-057f6b4e921c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Go City: San Francisco All-Inclusive Pass with 30+ Attractions £77 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/go-city-san-francisco-all-inclusive-pass-with-30-attractions.a219896.activity-details) ![Visit de Young Museum in Golden Gate Park](https://mediaim.expedia.com/localexpert/852149/5f951497-8465-48c2-bf9a-eff985a5464e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### de Young Museum General Admission Ticket £15 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/de-young-museum-general-admission-ticket.a852149.activity-details) ![Alcatraz Ticket with Roundtrip Ferry & Hop-On Hop-Off](https://mediaim.expedia.com/localexpert/192704/02e83615-017d-4057-af2f-68b4d1324bfa.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour £89 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/alcatraz-island-ticket-and-hop-on-hop-off-bus-tour.a192704.activity-details) ![SkyStar Wheel Fishermans Wharf. San Francisco's first waterfront observation Wheel!](https://mediaim.expedia.com/localexpert/47499798/9452154d-ee17-41e6-9ddd-12e7a5815ec4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### SkyStar Wheel Ticket in San Francisco £14 per adult **78%** of travellers recommend [](https://expedia.co.uk/things-to-do/skystar-wheel-ticket-in-san-francisco.a47499798.activity-details) [See all activities in San Francisco](https://expedia.co.uk/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities) --- ## Top hotels in Mission District ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Golden Gateway by IHG 1500 Van Ness Ave San Francisco CA Fully refundableReserve now, pay when you stay £108 17 Feb - 18 Feb includes taxes & fees Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ... 8.8/10 Excellent! (5,190 reviews) Nice s Reviewed on 28 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=10538&PinnedHotelID=10538&HadPinnedHotel=true®ionId=134035) ![Hotel Riu Plaza Fisherman's Wharf](https://images.trvl-media.com/lodging/1000000/30000/24700/24625/6fb55356_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Plaza Fisherman's Wharf 2500 Mason St San Francisco CA £131 10 Feb - 11 Feb includes taxes & fees Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ... 8.8/10 Excellent! (7,314 reviews) Everything was fantastic from check-in the beauty of the hotel the cleanliness the ease of parking friendlyness of the staff the room was made up perfectly truly enjoyed the great breakfast five stars. Reviewed on 26 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=10%2F02%2F2026&endDate=11%2F02%2F2026&selected=24625&PinnedHotelID=24625&HadPinnedHotel=true®ionId=134035) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton San Francisco Financial District 750 Kearny St San Francisco CA £93 15 Feb - 16 Feb includes taxes & fees Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ... 8.6/10 Excellent! (2,335 reviews) Favorite place to stay when visiting for the weekend. The beds are always soft, rooms are clean. The tvs have streaming apps. Views are beautiful. The only downside is parking is extremely expensive. Reviewed on 26 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=15%2F02%2F2026&endDate=16%2F02%2F2026&selected=4302&PinnedHotelID=4302&HadPinnedHotel=true®ionId=134035) ![Comfort Inn by the Bay](https://images.trvl-media.com/lodging/1000000/10000/6000/5984/d439a184_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn by the Bay 2775 Van Ness Ave San Francisco CA £87 11 Feb - 12 Feb includes taxes & fees Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the breakfast and the helpful ... 8.2/10 Very Good! (1,299 reviews) Our Hotel room was bit small but was very clean and comfortable. Breakfast was good with lots of options and location was great. Very safe walkable area and close to lots of tourist attractions. Great little deli right across street was a bonus for quick bite to eat after long day touring . Underground ... Reviewed on 29 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=11%2F02%2F2026&endDate=12%2F02%2F2026&selected=5984&PinnedHotelID=5984&HadPinnedHotel=true®ionId=134035) ![Hyatt Place San Francisco Downtown](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Place San Francisco Downtown 701 3rd St San Francisco CA £129 20 Feb - 21 Feb includes taxes & fees Stay at this hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and parking (surcharge). Our guests praise the breakfast and the helpful staff in ... 9.2/10 Wonderful! (1,958 reviews) Very clean, nice staff, beautiful hotel and comfortable accomodations. We'll stay here again. 1 block from giants Reviewed on 19 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=20%2F02%2F2026&endDate=21%2F02%2F2026&selected=31419890&PinnedHotelID=31419890&HadPinnedHotel=true®ionId=134035) ![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Club Quarters Hotel in San Francisco 424 Clay St San Francisco CA £91 16 Feb - 17 Feb includes taxes & fees Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ... 8.8/10 Excellent! (2,918 reviews) Kitchen has no cookware. Nice room tho Reviewed on 20 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=16%2F02%2F2026&endDate=17%2F02%2F2026&selected=912982&PinnedHotelID=912982&HadPinnedHotel=true®ionId=134035) [See all 4,969 properties in Mission District](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=31%2F01%2F2026&endDate=01%2F02%2F2026®ionId=134035) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Mission District hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=2026-01-30&endDate=2026-01-31)[30 Jan - 31 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=2026-01-30&endDate=2026-01-31) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=2026-01-31&endDate=2026-02-01)[31 Jan - 1 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=2026-01-31&endDate=2026-02-01) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026)[30 Jan - 1 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=134035&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026) --- ### Other neighbourhoods around Mission District ![Aerial View Of Urban Neighborhood ](https://images.trvl-media.com/place/6155705/000d8af2-94e1-4af8-bbaf-91af84845baa.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Noe Valley Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city. [](https://expedia.co.uk/San-Francisco-Noe-Valley.dx6155705) ![South of Market which includes skyline, a park and cbd](https://images.trvl-media.com/place/160166/f4a16719-d8ac-4494-aeaa-4bbf3b1bebfc.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South of Market 3.5/5(113 area reviews) Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping. [](https://expedia.co.uk/San-Francisco-South-Of-Market.dx160166) ![Anchor Brewing Company featuring a city](https://images.trvl-media.com/place/6155048/24053e58-3c93-4737-af35-eaecf9c08a12.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Potrero Hill The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Museum of Craft & Design are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area. [](https://expedia.co.uk/San-Francisco-Potrero-Hill.dx506137) ![Alamo Square showing heritage architecture, a house and a coastal town](https://images.trvl-media.com/place/507476/fa501f80-0e96-489f-8954-4d991a4502b0.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Western Addition 4/5(24 area reviews) Alamo Square and Painted Ladies are top sights in Western Addition, and you should be sure to explore the popular shops. Hop aboard the metro at Duboce Avenue & Noe Street Station or Duboce Ave & Church St Stop to see more sights in the area. [](https://expedia.co.uk/San-Francisco-Western-Addition.dx173536) ![Downtown San Francisco featuring railway items](https://images.trvl-media.com/place/6151902/22bc1dd6-2f5f-4efc-bbac-d6cb6e07fc99.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown San Francisco 3/5(52 area reviews) Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city. [](https://expedia.co.uk/San-Francisco-Downtown-San-Francisco.dx6151902) ![Union Square featuring a skyscraper and a city](https://images.trvl-media.com/place/800129/895a1fcb-3136-48af-a057-777a91829d9b.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Union Square 4/5(287 area reviews) Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city. [](https://expedia.co.uk/San-Francisco-Union-Square.dx800129) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Mission District Travel Guide ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - [5 Star Hotels in Noe Valley ](https://www.expedia.co.uk/5Star-Noe-Valley-San-Francisco-Hotels.s50-n6155705-0.Travel-Guide-Filter-Hotels) - [Hotels near Alamo Square ](https://www.expedia.co.uk/Alamo-Square-Hotels.0-l507476-0.Travel-Guide-Filter-Hotels) - [Bernal Heights Hotels ](https://www.expedia.co.uk/Bernal-Heights-San-Francisco-Hotels.0-n553248621561136356-0.Travel-Guide-Filter-Hotels) - [Hotels near Bill Graham Civic Auditorium ](https://www.expedia.co.uk/Bill-Graham-Civic-Auditorium-Hotels.0-l6155057-0.Travel-Guide-Filter-Hotels) - [Buena Vista Hotels ](https://www.expedia.co.uk/Buena-Vista-San-Francisco-Hotels.0-n553248635976482255-0.Travel-Guide-Filter-Hotels) - 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[Visit Theater District ](https://www.expedia.co.uk/San-Francisco-Theater-District.dx6151869) - [Visit Union Square ](https://www.expedia.co.uk/San-Francisco-Union-Square.dx800129) - [San Francisco Holidays ](https://www.expedia.co.uk/San-Francisco.d178305.Holidays-City-Breaks) - [Visit San Francisco ](https://www.expedia.co.uk/San-Francisco.dx178305) - [South of Market Holidays ](https://www.expedia.co.uk/South-Of-Market.d160166.Holidays-City-Breaks) - [Southern Exposure ](https://www.expedia.co.uk/Southern-Exposure-Mission-District.d553248621533113917.Attraction) - [Twin Peaks ](https://www.expedia.co.uk/Twin-Peaks-Eureka-Valley.d502560.Attraction) - [Victoria Manalo Draves Park ](https://www.expedia.co.uk/Victoria-Manalo-Draves-Park-Downtown-San-Francisco.d553248621533114847.Attraction) - [Avis Rental Cars in Downtown San Francisco ](https://www.expedia.co.uk/Avis-Car-Rentals-In-Downtown-San-Francisco.d6151902-c41.Car-Rental-Guide-Suppliers) - [Car hire near Downtown San Francisco ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-San-Francisco.d6151902.Car-Hire-Guide) - [Car hire near San Francisco ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Francisco.d178305.Car-Hire-Guide) - [Hertz Rental Cars in Downtown San Francisco ](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Downtown-San-Francisco.d6151902-c40.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in San Francisco ](https://www.expedia.co.uk/Hertz-Car-Rentals-In-San-Francisco.d178305-c40.Car-Rental-Guide-Suppliers) - [Things to do in San Francisco ](https://www.expedia.co.uk/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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