Mission District Holidays from £644

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Your Mission District Holiday

Make travel planning easy by reserving a holiday package to Mission District. Let us take care of the small stuff, so you can focus on soaking up everything this neighbourhood can offer. Your trip to Mission District wouldn't be complete without seeing top attractions nearby such as Lombard Street, University of San Francisco and University of California, San Francisco. No matter what your dream Mission District holiday may look like, you can turn it into reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
Hotel Zetta San Francisco

Hotel Zetta San Francisco

4 out of 5
Downtown San Francisco
per person
1 Oct - 6 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
8.8/10 Excellent! (1,000 reviews)
We enjoyed our 3day stay at Hotel Zetta, and loved the location as well as the games/arcade available for guests! There was complimentary coffee and donuts, and hotel was very clean. We weren’t able to check in early but they held our bags til our rooms were ready.

Reviewed on 4 Aug 2025

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
per person
1 Oct - 6 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (431 reviews)
Ice place I would viy

Reviewed on 8 Aug 2025

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
Fisherman's Wharf
per person
1 Oct - 6 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (1,403 reviews)
We loved our stay here and would come back again! Such a great location and clean quiet rooms!

Reviewed on 9 Aug 2025

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
per person
1 Oct - 6 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9/10 Wonderful! (6,641 reviews)
Close to everything

Reviewed on 9 Aug 2025

Argonaut Hotel

Argonaut Hotel

4.5 out of 5
Fisherman's Wharf
per person
1 Oct - 6 Oct
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.4/10 Exceptional! (1,094 reviews)
Nice hotel. Fisherman warf is a little sketchy.

Reviewed on 10 Aug 2025

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Fisherman\'s Wharf featuring a bay or harbour

Fisherman's Wharf

1 out of top 10 points of interest in this area
5/5(4 area reviews)

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Top hotels in Mission District

Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
Fully refundable
The price is £89 per night from 17 Aug to 18 Aug
£89
17 Aug - 18 Aug
includes taxes & fees
7.6/10 Good! (2,004 reviews)
"Likes the quick check in and check out, didn’t like the parking lot"

Reviewed on 8 Aug 2025

Crowne Plaza San Francisco Airport by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £106 per night from 24 Aug to 25 Aug
£106
24 Aug - 25 Aug
includes taxes & fees
8.6/10 Excellent! (1,605 reviews)
"lots of chinese food. parking was expensive but convenient. coffee bar in lobby in morning was convenient."

Reviewed on 7 Aug 2025

Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
The price is £151 per night from 26 Aug to 27 Aug
£151
26 Aug - 27 Aug
includes taxes & fees
8.8/10 Excellent! (6,643 reviews)
"Beautiful hotel Excellent free buffet breakfast Very comfortable bed Location was wonderful, walking distance to the wharf."

Reviewed on 9 Aug 2025

Hotel Riu Plaza Fisherman's Wharf
See all 4,703 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Mission District travel package cost?
Cross off another part of the world with our Mission District travel packages, which start from just £644. Pick the flights and hotels that suit your plans. Then, add on a couple of sightseeing activities for a one-of-a-kind getaway.
If I'm not able to travel, can I cancel my Mission District travel package?
Certainly, and we'll help you every step of the way. You may be able to cancel or change your Mission District travel package at no cost within 24 hours of booking. But you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, visit our Customer Service Portal for more information.
How do I get a cheap travel package to Mission District?
You'll save loads of cash if you combine your car rentals, flights and hotels into a Mission District travel package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer over 550 partner airlines and 1,000,000 properties across the world, which means you'll always have plenty of variety to choose from. Want to save even more? Add some popular activities to your package deal and unlock even more bargains! After all, travel is about more than just getting to your destination.
Does Expedia offer Book Now, Pay Later Mission District holidays?
Yes. Expedia has joined forces with online lender Klarna to help you easily pay for your holiday in instalments. Simply pick the payment plan that suits you best during the checkout process and take away the stress of budgeting for your next trip. Remember to bundle your flights, hotel and car hire with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: Klarna has easy monthly payment plans that suit all budgets, so you can book that well-deserved holiday sooner.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your holiday in multiple transactions.
  • Low deposit holidays: Pressing the "book now" button is easier with this plan. Simply put down a small deposit on your booking and then start working on your travel itinerary.

Where should I stay in Mission District?
Most who travel to Mission District put both Golden Gate Bridge and Pier 39 on their to-do lists. Why not book a hotel near these fantastic attractions?
What are the top hotels in Mission District?
Book a stay at Hilton San Francisco Financial District. It's one of this area's most sought-after hotels. Another reputable option in Mission District is San Francisco Marriott Marquis.
How far in advance should I book my Mission District holiday?
Travellers are normally able to browse international flights on Expedia up to a year in advance of departure. Booking last minute? With a stroke of luck, it's still possible to purchase an affordable ticket only weeks before your journey.
What does an Expedia Mission District travel package include?
Rental cars, hotels and flights, or any combination of them — it's your choice. Whether you're headed to Mission District with the family or travelling with your friends, there's a bundle to fit your budget and style. Once you've made your booking, why not add on a few tours as well?
What should I know before booking a Mission District travel package?
So many places to wander around, so many things to experience. With a package, you'll be able to cross more of them off your list. Bundle your flights, rental cars and hotels and get ready to save.
Can I choose my airline with a Mission District Expedia travel package?
The choice is all yours! We offer more than 550 airlines around the world, so you can design your Mission District adventure according to your budget and travel needs.

Popular places to visit

Southern Exposure

You can spend time studying the exhibits at Southern Exposure during your travels in San Francisco. Take in the acclaimed art galleries and beautiful sunsets in this vibrant area.

Southern Exposure

Things to do

Secret Food Tours San Francisco

Secret Food Tours San Francisco

£67
per adult
Secret Food Tours San Francisco
Silicon Valley Tour in Self Driving Car

Silicon Valley Tour in Self Driving Car

£22
per traveller
Silicon Valley Tour in Self Driving Car
Mission District Food and Culture Tour

Mission District Food and Culture Tour

£29
per adult
Mission District Food and Culture Tour
See all activities in San Francisco

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.