Mission District Holidays from £808

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Your Mission District Holiday

Make travel planning easy by reserving a holiday package to Mission District. Let us take care of the small stuff, so you can focus on soaking up everything this neighbourhood can offer. Your trip to Mission District wouldn't be complete without seeing top attractions nearby such as Lombard Street, University of San Francisco and University of California, San Francisco. No matter what your dream Mission District holiday may look like, you can turn it into reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
Union Square Plaza Hotel

Union Square Plaza Hotel

2 out of 5
Union Square
Price was £1,348, price is now £808 per person
£808
per person
16 Aug - 21 Aug
found 13 hours ago
Return direct flight included
London (LHR) to San Francisco (SFO)
7.2/10 Good! (1,019 reviews)
There was both a convention and World Cup when we went, but this was very expensive for what you got. The staff was very friendly and our rooms were clean, but this an old hotel that is very beaten up. The shampoo and conditioner bottles are not labeled and the towels were very thin (and we did not get hand towels the second day). Good location if you are kind of desperate

Reviewed on 19 Jun 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was £3,501, price is now £1,988 per person
£1,988
per person
14 Sept - 21 Sept
just found
Return direct flight included
Edinburgh (EDI) to San Francisco (SFO)
9/10 Wonderful! (7,477 reviews)
Long breakfast wait is long if you’re not arrive early. Parking fee is relatively cheap compared to nearby hotels. Bathroom door isn’t well planned.

Reviewed on 28 Jun 2026

1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
Price was £3,385, price is now £1,937 per person
£1,937
per person
11 Sept - 16 Sept
found 14 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
9.2/10 Wonderful! (561 reviews)
The room was immaculate, and the food was amazing. I highly recommend this hotel.

Reviewed on 13 Jun 2026

The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Save 100% on your flight
Price was £3,038, price is now £1,847 per person
£1,847
per person
14 Sept - 21 Sept
just found
Return direct flight included
Edinburgh (EDI) to San Francisco (SFO)
9.2/10 Wonderful! (718 reviews)
Amazing stay for our wedding anniversary. Such a lovely Inn. Highly recommend!

Reviewed on 13 Jun 2026

Motel 6 San Francisco, CA – Civic Center

Motel 6 San Francisco, CA – Civic Center

2 out of 5
Downtown San Francisco
Price was £1,535, price is now £949 per person
£949
per person
14 Sept - 19 Sept
found 13 hours ago
Return flight included
London (LHR) to San Francisco (SFO)
7/10 Good! (567 reviews)
This place seems scary if your not used to being in the city and who knows, maybe it is. I'm not of that life. My brother and I had no issues the few days we were there though. It a very conveniently placed motel being close to a lot. The place was definitely aged and could use some upgrades, but seemed very clean. The beds were amazingly soft and comfortable for a motel. Probably the best part.

Reviewed on 27 May 2026

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
A marina with various boats docked, including a yellow and white boat named 'Golden Gate'.

Fisherman's Wharf

1 out of top 10 points of interest in this area
5/5(4 area reviews)

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Top hotels in Mission District

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £212 per night from 12 Jul to 13 Jul
£212
12 Jul - 13 Jul
includes taxes & fees
9.4/10 Exceptional! (2,313 reviews)
"The stunning view and lobby is what I like most! Plus the cleanliness and space of the rooms makes the stay worthwhile. Very walkable spot going to stations.. Glad we are able to stay! We will dome back!"

Reviewed on 28 Jun 2026

Hyatt Regency San Francisco
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
425 North Point San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £152 per night from 12 Jul to 13 Jul
£152
12 Jul - 13 Jul
includes taxes & fees
9.2/10 Wonderful! (1,990 reviews)
"Great hotel nice and clean and so close to the wharf"

Reviewed on 28 Jun 2026

Hotel Zoe Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is £128 per night from 12 Jul to 13 Jul
£128
12 Jul - 13 Jul
includes taxes & fees
Holiday Inn Golden Gateway by IHG
See all 4,473 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
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Beach Holidays
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Family Friendly Holidays

Frequently asked questions

How much does a Mission District travel package cost?
Cross off another part of the world with our Mission District travel packages, which start from just £808. Pick the flights and hotels that suit your plans. Then, add on a couple of sightseeing activities for a one-of-a-kind getaway.
If I'm not able to travel, can I cancel my Mission District travel package?
Certainly, and we'll help you every step of the way. You may be able to cancel or change your Mission District travel package at no cost within 24 hours of booking. But you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans suddenly change, visit our Customer Service Portal for more information.
How do I get a cheap travel package to Mission District?
You'll save loads of cash if you combine your car rentals, flights and hotels into a Mission District travel package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer over 550 partner airlines and 1,000,000 properties across the world, which means you'll always have plenty of variety to choose from. Want to save even more? Add some popular activities to your package deal and unlock even more bargains! After all, travel is about more than just getting to your destination.
Does Expedia offer Book Now, Pay Later Mission District holidays?
Yes. Expedia has joined forces with online lender Klarna to help you easily pay for your holiday in instalments. Simply pick the payment plan that suits you best during the checkout process and take away the stress of budgeting for your next trip. Remember to bundle your flights, hotel and car hire with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: Klarna has easy monthly payment plans that suit all budgets, so you can book that well-deserved holiday sooner.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your holiday in multiple transactions.
  • Low deposit holidays: Pressing the "book now" button is easier with this plan. Simply put down a small deposit on your booking and then start working on your travel itinerary.

Where should I stay in Mission District?
Most who travel to Mission District put both Golden Gate Bridge and Pier 39 on their to-do lists. Why not book a hotel near these fantastic attractions?
What are the top hotels in Mission District?
Book a stay at Hilton San Francisco Financial District. It's one of this area's most sought-after hotels. Another reputable option in Mission District is San Francisco Marriott Marquis.
How far in advance should I book my Mission District holiday?
Travellers are normally able to browse international flights on Expedia up to a year in advance of departure. Booking last minute? With a stroke of luck, it's still possible to purchase an affordable ticket only weeks before your journey.
What does an Expedia Mission District travel package include?
Rental cars, hotels and flights, or any combination of them — it's your choice. Whether you're headed to Mission District with the family or travelling with your friends, there's a bundle to fit your budget and style. Once you've made your booking, why not add on a few tours as well?
What should I know before booking a Mission District travel package?
So many places to wander around, so many things to experience. With a package, you'll be able to cross more of them off your list. Bundle your flights, rental cars and hotels and get ready to save.
Can I choose my airline with a Mission District Expedia travel package?
The choice is all yours! We offer more than 550 airlines around the world, so you can design your Mission District adventure according to your budget and travel needs.

Stay near popular Mission District attractions

A park with people sitting on the grass, a school building, and a cityscape in the background.

Mission Dolores Park

9.4/5 (3 reviews)
Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.
See properties

Things to do

San Francisco City Lights Cruise

California Sunset Cruise (2-hours)

£43
per adult
94% of travellers recommend
California Sunset Cruise (2-hours)
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

£36
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

£81
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
See all activities in San Francisco

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.