A tropical island with palm trees and a clear blue sky.

Holiday Homes in Panama

Compare and save
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Panama Accommodation: Most Popular Cities to Stay

Our top choices for Panama holiday homes

1. Villas Residences by Playa Caracol Resorts

Villas Residences by Playa Caracol Resorts
3.5 star property
Punta Chame
8.4 out of 10, Very good, (8 reviews)
"The place was equipped, clean and amazing location, we truly enjoyed and will come back , thank you"
United States
Saro
The price is £94
includes taxes & fees
17 Aug - 18 Aug
Villas Residences by Playa Caracol Resorts

2. Ecoresort: We are Panamas leading honey producer and butterfly exhibit.

Ecoresort: We are Panamas leading honey producer and butterfly exhibit.
Boquete
10.0 out of 10, Exceptional, (14 reviews)
"Little cottages in an unbelievable garden setting. Communications with Emily were clear and she was always helpful. Lovely breakfast!"
Canada
William
Ecoresort: We are Panamas leading honey producer and butterfly exhibit.

3. Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.

Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.
Bajo Boquete
10.0 out of 10, Exceptional, (12 reviews)
"Easy peezy to access, owner did a great job getting us oriented and settled in. Our stay was super relaxing, enjoyed the Boquete area, the facilities at Valle Escondido Resort, and the residence was well kept, modern, and clean. "
United States
Jeremy T.
Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.

4. Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden

Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden
Boca Chica
10.0 out of 10, Exceptional, (2 reviews)
"The property is beautiful, peaceful and well appointed. We enjoyed the pool and the hummingbirds that visit the flowers throughout the day. The kitchen is well stocked with all the equipment you need to prepare meals. I'd stay here again - no hesitation!"
United States
Mary S.
Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden

5. Private Villa at Red Frog Beach Resort

Private Villa at Red Frog Beach Resort
Red Frog Beach
9.8 out of 10, Exceptional, (10 reviews)
"Gorgeous, spacious Villa at an absolutely beautiful resort. We loved the beaches and beach bars/restaurants. Brett is a responsive and helpful host. Shout out to Oliver at Red Frog who treated us as valued guests even though we rented through VRBO. Overall we had a wonderful vacation."
Canada
Angela B.
Private Villa at Red Frog Beach Resort

6. Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (68 reviews)
"Lost our key partying about in Bocas town, came back to the hotel at 3am and the owner (great guy) let us back in!! Our savior and the accommodations (AC in particular) were very nice. Would 100% stay here again."
United States
Carter
The price is £21
includes taxes & fees
11 Aug - 12 Aug
Surfari Bocas

7. Aires frescos de Boquete

Aires frescos de Boquete
3.0 star property
Alto Boquete
8.0 out of 10, Very good, (6 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is £37
includes taxes & fees
12 Aug - 13 Aug
Aires frescos de Boquete

8. Susan Fish Camp in Playa Morrillo, Veraguas

Susan Fish Camp in Playa Morrillo, Veraguas
Morrillo
10.0 out of 10, Exceptional, (9 reviews)
"Fantastic place to stay in paradise! Look no further...this is the only place to stay if you're heading to Playa Morrillo area! "
United States
David M.
Susan Fish Camp in Playa Morrillo, Veraguas

9. Brand NEW Home Over on the Water

Brand NEW Home Over on the Water
Bocas del Toro
8.6 out of 10, Excellent, (7 reviews)
"The stay was good. We enjoyed the water, snorkeling and using the water board. "
United States
Sandy K.
The price is £55
includes taxes & fees
11 Aug - 12 Aug
Brand NEW Home Over on the Water

10. Ventanas del Mar by Playa Caracol Resort

Ventanas del Mar by Playa Caracol Resort
4.0 star property
Punta Chame
The price is £89
includes taxes & fees
1 Sept - 2 Sept
Ventanas del Mar by Playa Caracol Resort

11. Bocas Villas - Private Acqua Villas

Bocas Villas - Private Acqua Villas
Punta Caracol
9.2 out of 10, Wonderful, (7 reviews)
"The place is magical, right on the water, with a beautiful coral reef teeming with fish below for snorkeling. There's a small kayak for you to use; I used it to watch the sunset and it was beautiful. My wife loved this place. It's quiet, with a very peaceful vibe. It's about a 15-minute boat ride to get there. The owner, Philip, was very attentive and kind. This place definitely has a beautiful vibe; highly recommended."
United States
Daniel
The price is £99
includes taxes & fees
11 Aug - 12 Aug
Bocas Villas - Private Acqua Villas

12. The Sea Spot! Casa Del Mar

The Sea Spot! Casa Del Mar
Bocas del Toro
10.0 out of 10, Exceptional, (2 reviews)
"A magical home with so many activities for everyone. It was very hard for us to say goodbye. Can’t wait to return one day."
United States
jason o.
The Sea Spot! Casa Del Mar

13. Jacuzy, pool and lake at the same house.

Jacuzy, pool and lake at the same house.
Colon
7.4 out of 10, Good, (3 reviews)
"Great. Please take care of the cat"
United States
KENNETH E.
The price is £54
includes taxes & fees
11 Aug - 12 Aug
Jacuzy, pool and lake at the same house.

14. Beachfront House at La Vida Resort

Beachfront House at La Vida Resort
3.0 star property
Bastimentos
8.6 out of 10, Excellent, (4 reviews)
"The beach,ocean and cottage was beautiful."
Canada
Michael
Beachfront House at La Vida Resort

15. Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities

Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities
Boquete
10.0 out of 10, Exceptional, (13 reviews)
"Stunning home, quiet and peaceful! We loved our stay here, two weeks was not enough. We are planning to return next year. We were going to rent a car but did not find it necessary as we could walk everywhere. Very highly recommend this home!"
United States
JoAnne L.
Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities

16. House in Boquete, House in Boquete with king beds and hot tub (565749)

House in Boquete, House in Boquete with king beds and hot tub (565749)
Alto Jaramillo
10.0 out of 10, Exceptional, (7 reviews)
"Great place to stay. Loved the amenities and enjoyed the views! "
United States
Doug W.
The price is £317
includes taxes & fees
24 Aug - 25 Aug
House in Boquete, House in Boquete with king beds and hot tub (565749)

17. Luxury 3BR Pool, SPA & Golf Resort Near Canal 302

Luxury 3BR Pool, SPA & Golf Resort Near Canal 302
Cocoli
Luxury 3BR Pool, SPA & Golf Resort Near Canal 302

18. The Sea Spot! Hip-Nautic Floating Lodge

The Sea Spot! Hip-Nautic Floating Lodge
Bocas del Toro
The Sea Spot! Hip-Nautic Floating Lodge

19. Unique house with direct access to the beach, four bedrooms, balcony and design

Unique house with direct access to the beach, four bedrooms, balcony and design
Ciudad de Panamá
Unique house with direct access to the beach, four bedrooms, balcony and design

20. House with Pool and Ocean View | PH Costa Grande

House with Pool and Ocean View | PH Costa Grande
Nueva Gorgona
The price is £92
includes taxes & fees
11 Aug - 12 Aug
House with Pool and Ocean View | PH Costa Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews

Find out more about Panama

Panama Holiday Homes: Find the Perfect Place


What is the best time to enjoy a holiday home in Panama?

It might be best to get a rental house in when the weather is ideal for enjoying local surroundings. If you go during the off-season months, there might be fewer tourists and often lower rates, like in .


How many holiday homes are available for rent in Panama?

Choose from 397 beautiful holiday homes in Panama for your getaway.


How much is a holiday home in Panama?

You can find perfect holiday homes in Panama for as low as £21 per night. Holiday home prices vary depending on what time of year you visit, whether the home is in the city centre or near popular sightseeing spots, and what kinds of amenities it offers.


How can I get the best deal on a holiday home in Panama?

Find the best deals on Panama holiday homes by entering dates and the number of travellers in the search bar. You can use the map feature to view prices and more specific locations of several accommodations all at once. Or filter your search results by star rating, price, number of bedrooms, types of amenities, and accessibility features—Expedia offers incredible deals for every budget.


Why should I book a holiday home in Panama?

There’s no better way to spend your well-earned holiday than in a private, cosy Panama holiday home. You’ll be able to fit all travellers in your group and have a place to call home while you explore Panama.


What amenities are available in a private holiday home?

Depending on your budget and the neighbourhood you choose, you’ll find amenities like a private pool, hot tub, free parking, a full-service kitchen or kitchenette, in-home laundry and WiFi. Your Panama holiday won’t be complete without a beautiful view and easy access to popular activities, use our filter to browse our offers.


Why should I book a holiday home with Expedia?

With Expedia, you’ll earn points on every booking and get incredible deals and member prices. Choose from a vast inventory of holiday homes in Panama—and book all your travel in one place. Save even more when you bundle your bookings together. Add a Panama car hire to your holiday property into a holiday package.


What are the cancellation and flexibility options?

We suggest using the “free cancellation” filter during your search to make sure your booking is flexible. Some accommodations accept and refund cancellations within a specific timeframe, while others may be non-refundable. Before you book, check your rental terms, or reach out to our customer service portal for further assistance.

Panama Holiday Homes information

Number of reviews
168
Accommodation
397 Holiday Homes
Lowest Price
£21
Highest Price
£317

Explore a world of travel with Expedia