Title: Holiday Rentals Panama from £68: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Panama Travel Guide](https://expedia.co.uk/Panama.dx142)[Panama Hotels](https://expedia.co.uk/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Flights](https://expedia.co.uk/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Hire](https://expedia.co.uk/Destinations-In-Panama.d142.Car-Hire-Destinations)[Panama Holidays](https://expedia.co.uk/Panama.d142.Holidays-City-Breaks) ![Panama showing island views, landscape views and tropical scenes](https://images.trvl-media.com/place/142/329febe6-4cd6-48f7-a9e8-71ea862bef81.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by PhotoJoy # Search Holiday Rentals in Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Panama Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) ## Top Holiday Rentals in Panama ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Costa del Este 9.4/10 Exceptional (140) "Wonderful place great staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shantia £105 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/edba2188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/568d88f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Balcony](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/97c51ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista 7.8/10 Good (205) "The view was amazing and the place was great could stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yonnette [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Standard Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/0a056e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/f71ce331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/b2adfd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/20a4e482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Bella Vista 8.8/10 Excellent (479) "Good location, quick walk to the subway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynden [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen | Fridge, microwave, oven, electric kettle](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in Santa Ana 9.2/10 Wonderful (50) "Great stay, would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/f0ebed1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Casco Viejo 9.4/10 Exceptional (168) "Our stay at Las Clementinas was amazing. The ambiance, decor, and central location to all things in Casco Viejo made our trip magical. Not only was the hotel beautiful, the staff was incredibly warm, helpful and welcoming. The restaurant in the hotel was absolutely delicious. I would stay here ten times over. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda £104 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/7a081d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/48e220ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco 7.4/10 Good (150) "Clean room good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gideon £136 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c337dae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/cb84ac89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/5b01afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in Casco Viejo 10/10 Exceptional (165) "The room was spotless, the location perfect, and the staff was absolutely superb!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Honeymoon Studio, Hot Tub, Valley View | 2 bedrooms, Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/f1920aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Studio Suite, 1 Queen Bed, Kitchenette, Mountain View | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/7a6a1a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Studio, Hot Tub, Valley View | 2 bedrooms, Egyptian cotton sheets, premium bedding, Tempur-Pedic beds](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/b46898c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/c5c10649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa in Boquete 8.8/10 Excellent (125) "Priced right, easy walk to town, safe, quiet & overall great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.co.uk/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Apartment | Balcony view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2d6249fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Apartment | Beach/ocean view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/a7c64715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/077501d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista 8.2/10 Very good (44) "Great place , very clean all good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) harley £148 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment (3G) | Balcony](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/8ac950b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/dc7a8e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/f5328136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in El Chorrillo 9.2/10 Wonderful (42) "Nice place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tesha £95 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11B) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/w2996h2000x4y0-ef85e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09H) | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11I) | 1 bedroom, down duvets, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/0f7befd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco 9.2/10 Wonderful (52) "This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mario £104 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Design Suite, 1 King Bed, Mountain View | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/903374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/19d8b56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/f86e54de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Garden View | Living area | 43-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Boquete 9.6/10 Exceptional (84) "Nice stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos [](https://www.expedia.co.uk/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Apartment (CC4B) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC3B) | Private kitchen | Fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/5e7a29e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC4A) | Dining room](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d8108baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A) | 2 bedrooms, premium bedding, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d5409722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo 8.6/10 Excellent (19) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jad £100 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/576f28cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/8679b43b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/3fb46571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/26ebabc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aparthotel in San Francisco 10/10 Exceptional (5) "Loved the property and the location, it was clean , nice and I really enjoyed my stay there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aron [](https://www.expedia.co.uk/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information) ![Apartment, 2 Bedrooms (2C) | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3a166248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Private kitchen | Fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/56b38ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1B) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/5945d7c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/350b1bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo 8.4/10 Very good (45) "I always love to stay at Wynwood properties in Panama " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto B £68 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Apartment (1D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/8f7fd7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen | Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/0c622720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/b50fc181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo 8.4/10 Very good (20) "The apartment was very clean and looked just like the pictures! Loved the view of the water from the wrap around balcony. We never felt unsafe walking to restaurants in the evening. Supermercado Rey was a 3 to 4 minute walk away. We have stayed in Casco Viejo several times. Many places are loud due to rooftop bars playing music until 3 am. This apartment was extremely quiet! Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patti £81 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (8B) | Private kitchen | Fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/46fac3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4f5c676f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | 2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/155ac5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in San Francisco 7.8/10 Good (24) "I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shamia [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Apartment, 2 Bedrooms (CM2) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (CM5) | Living area | 55-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/3681eb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Dining room](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/242a1c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (CM5) | 2 bedrooms, premium bedding, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/f82421c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo 9.8/10 Exceptional (24) " It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Navyatha £442 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Deluxe Apartment | 1 bedroom, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Private kitchen | Fridge, microwave, coffee/tea maker, electric kettle](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/7d5fb04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/af0ed434.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Casco Viejo 7.4/10 Good (40) "The nightlife around there was incredible" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix £69 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area | 65-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a2b1fb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/b3283f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/32689428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apartment in Bella Vista 9.4/10 Exceptional (46) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANGEL [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-08&endDate=2025-12-09®ionId=142&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=VR_BF_PROMO_142) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Holiday-Rental-Destinations) ## Top Panama Hotel Reviews ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The view and room was AMAZING!! The staff was welcoming and food was great! " [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "For an airport hotel, this was lovely! The perfect place for us to recoup after a long day of flying. The pool and outdoor space was wonderful. There isn’t much around in terms of stores or entertainment, but it is quiet and clean." [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Everything" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Fabulous stay!" [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Nice hotel with clean room, wide choice at breakfast buffet. Very clean everywhere. Well located. Will come back." [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "The rooms were spotless and the staff was A-plus. The location was great; close to restaurants and shops." [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Room and the facility were exceptionally clean and well maintained. All of the staff was extremely helpful and friendly. Especial thank to bar staff in the main lobby and the master of ceremonies." [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "excelente servicio y atencion" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Decent place to stay. Convenient and welcoming staff" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ## Find out more about Panama **Everything you need to know about** **Panama** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search.  **Panama holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama holiday rentals we have selected for you start as low as £68 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Panama rentals** At Expedia, we put the best Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Popular Panama Cities - All accommodation types in Panama - [Panama City Holiday Rentals](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals) - [Bocas del Toro Holiday Rentals](https://expedia.co.uk/Bocas-Del-Toro-Holiday-Rentals.d6023445.Travel-Guide-HolidayRentals) - [David Holiday Rentals](https://expedia.co.uk/David-Holiday-Rentals.d500195.Travel-Guide-HolidayRentals) - [Playa Coronado Holiday Rentals](https://expedia.co.uk/Playa-Coronado-Holiday-Rentals.d6053187.Travel-Guide-HolidayRentals) - [Las Tablas Holiday Rentals](https://expedia.co.uk/Las-Tablas-Holiday-Rentals.d6347532.Travel-Guide-HolidayRentals) - [Alto Boquete Holiday Rentals](https://expedia.co.uk/Alto-Boquete-Holiday-Rentals.d6245664.Travel-Guide-HolidayRentals) - [Apartments in Panama](https://expedia.co.uk/Panama-Apartments.d142-aaApartments.Travel-Guide-Accommodation) - [Holiday Homes in Panama](https://expedia.co.uk/Panama-Private-Holiday-Homes.d142-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Condo Rentals in Panama](https://expedia.co.uk/Panama-Condos.d142-aaCondos.Travel-Guide-Accommodation) - [B&B in Panama](https://expedia.co.uk/Panama-Bed-And-Breakfasts.d142-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Villas in Panama](https://expedia.co.uk/Panama-Villas.d142-aaVillas.Travel-Guide-Accommodation) - [Cabin Rentals in Panama](https://expedia.co.uk/Panama-Cabins.d142-aaCabins.Travel-Guide-Accommodation) - [Hostels in Panama](https://expedia.co.uk/Panama-Hostels.d142-aaHostels.Travel-Guide-Accommodation) - [Serviced Apartments in Panama](https://expedia.co.uk/Panama-Apart-Hotels.d142-aaApartHotels.Travel-Guide-Accommodation) - [Lodges in Panama](https://expedia.co.uk/Panama-Lodges.d142-aaLodges.Travel-Guide-Accommodation) - [Guest Houses in Panama](https://expedia.co.uk/Panama-Guest-Houses.d142-aaGuestHouses.Travel-Guide-Accommodation) - 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