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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.4 out of 10, Very good, (1,955 reviews)
"Will stay again, I loved it"
United States
Shelly Ann
The price is £118
includes taxes & fees
12 Nov - 13 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2. Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1,005 reviews)
"clean room nice place to stay"
Mexico
Anonymous traveller
The price is £93
includes taxes & fees
17 Nov - 18 Nov
Quality Suites San Diego Otay Mesa

3. Rodeway Inn San Diego South San Ysidro Border

Rodeway Inn San Diego South San Ysidro Border
2.0 star property
3.6 mi from Otay Mesa
8.0 out of 10, Very good, (322 reviews)
"Great service beautiful hotel"
United States
Guadalupe
The price is £64
includes taxes & fees
17 Nov - 18 Nov
Rodeway Inn San Diego South San Ysidro Border

4. Best Western Americana Inn

Best Western Americana Inn
2.5 star property
5 mi from Otay Mesa
8.8 out of 10, Excellent, (1,430 reviews)
"Great service from the staff!"
United States
Erika
The price is £89
includes taxes & fees
22 Nov - 23 Nov
Best Western Americana Inn

5. Valli Hi Motel

Valli Hi Motel
2.0 star property
4.9 mi from Otay Mesa
8.2 out of 10, Very good, (1,170 reviews)
"Clean rooms and nice staff"
United States
Wendy
The price is £69
includes taxes & fees
12 Nov - 13 Nov
Valli Hi Motel

6. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
8 mi from Otay Mesa
8.6 out of 10, Excellent, (1,800 reviews)
"Clean room , friendly staff , always helpful, breakfast good , always great to return"
United States
Luis
The price is £84
includes taxes & fees
29 Nov - 30 Nov
La Quinta Inn by Wyndham San Diego Chula Vista

7. The Rambler Hotel

The Rambler Hotel
3.0 star property
9.2 mi from Otay Mesa
9.0 out of 10, Wonderful, (2,205 reviews)
"Solid place to stay"
United States
Neal
The price is £76
includes taxes & fees
1 Dec - 2 Dec
The Rambler Hotel

8. Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
4.1 mi from Otay Mesa
9.8 out of 10, Exceptional, (1,030 reviews)
"I was very impressed with this hotel. The rooms were comfortable and modern and the staff was warm and welcoming."
United States
Rosemary
The price is £150
includes taxes & fees
29 Nov - 30 Nov
Ayres Hotel San Diego South - Chula Vista

9. SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
6.5 mi from Otay Mesa
9.6 out of 10, Exceptional, (823 reviews)
"Great hotel"
United States
leslie
The price is £140
includes taxes & fees
30 Nov - 1 Dec
SpringHill Suites by Marriott Chula Vista Eastlake

10. Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
8.1 mi from Otay Mesa
8.4 out of 10, Very good, (1,727 reviews)
"It was a nice hotel. I’d stay here again."
United States
Lori
The price is £89
includes taxes & fees
22 Nov - 23 Nov
Comfort Inn Chula Vista San Diego South

11. Howard Johnson by Wyndham National City/San Diego South

Howard Johnson by Wyndham National City/San Diego South
2.0 star property
11.3 mi from Otay Mesa
7.6 out of 10, Good, (1,194 reviews)
"Great stay for a stay !"
United States
Monserrat
The price is £59
includes taxes & fees
1 Dec - 2 Dec
Howard Johnson by Wyndham National City/San Diego South

12. Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
10.6 mi from Otay Mesa
9.0 out of 10, Wonderful, (1,168 reviews)
"Lovely place to stay, beautiful scenery. The only downside is everything is far away- gas station, restaurants, you have to UBER or have a rental car to travel for amenities outside of what the resort offers."
United States
Josh
The price is £200
includes taxes & fees
1 Dec - 2 Dec
Loews Coronado Bay Resort

13. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 mi from Otay Mesa
9.2 out of 10, Wonderful, (4,235 reviews)
"Clean room and really nice area for our stay"
United States
Brandon
The price is £110
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Marina Gateway Hotel

14. Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
4.4 mi from Otay Mesa
8.0 out of 10, Very good, (2,035 reviews)
"Me and my husband loved it we tried different ones and this one is one of the best from now on is going to be our favorite to stay,very clean and breakfast was so good so many options for breakfast"
United States
Edna
The price is £90
includes taxes & fees
22 Nov - 23 Nov
Best Western Chula Vista/Otay Valley Hotel

15. Hotel Palmeras Chula Vista

Hotel Palmeras Chula Vista
2.0 star property
8.9 mi from Otay Mesa
7.4 out of 10, Good, (2,466 reviews)
"Clean rooms nice staff"
United States
Wendy
The price is £53
includes taxes & fees
16 Nov - 17 Nov
Hotel Palmeras Chula Vista

16. Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
17.7 mi from Otay Mesa
9.4 out of 10, Exceptional, (2,224 reviews)
"Great stay!"
United States
Kimberly
The price is £83
includes taxes & fees
16 Nov - 17 Nov
Sycuan Casino Resort

17. Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique
3.0 star property
8.5 mi from Otay Mesa
8.8 out of 10, Excellent, (1,580 reviews)
"Really nice place"
United States
justin
The price is £91
includes taxes & fees
19 Nov - 20 Nov
Hercor Hotel - Urban Boutique

18. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
9 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,654 reviews)
"Great stay"
United States
Daniel
The price is £133
includes taxes & fees
10 Dec - 11 Dec
Holiday Inn Express San Diego South - Chula Vista by IHG

19. The Davis Downtown San Diego

The Davis Downtown San Diego
3.5 star property
East Village, 15 mi from Otay Mesa
8.0 out of 10, Very good, (637 reviews)
"Great hotel! Easy to use! Great price and location!"
United States
Robert Scott
The price is £63
includes taxes & fees
7 Dec - 8 Dec
The Davis Downtown San Diego

20. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
18.5 mi from Otay Mesa
8.4 out of 10, Very good, (1,495 reviews)
"Had a good stay"
United States
Yesenia
The price is £98
includes taxes & fees
17 Nov - 18 Nov
Crowne Plaza San Diego - Mission Valley by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Otay Mesa

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
8.4
Very good
1,955 reviews
View
A hotel room with a kitchenette, dining area, and a ceiling fan.
Quality Suites San Diego Otay Mesa
2.5 star property
7.2
Good
1,005 reviews
View
A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.
Ayres Hotel San Diego South - Chula Vista
3.0 star property
9.8
Exceptional
1,030 reviews
View
A spacious lobby with a fireplace, wooden furniture, and a chandelier.
Best Western Americana Inn
2.5 star property
8.8
Excellent
1,430 reviews
View
View from property
SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
9.6
Exceptional
823 reviews
View

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Top Otay Mesa Hotel Reviews

Frequently Asked Questions

What are the best hotels in Otay Mesa that travellers recommend?

Two of the best hotels in Otay Mesa that travellers recommend are the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. Visitors also highlight the great breakfast and comfortable beds. For added convenience, the hotel provides free buffet breakfast, suites, and connecting rooms, along with free rollaway extra beds and cribs. There is also an outdoor pool for relaxation.

Another highly recommended option is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. Guests consistently mention the comfortable and clean beds, the convenient location, and the friendly and professional staff. The hotel offers free breakfast, including a to-go option, along with free self-parking and accessible parking for vans, RVs, buses, and trucks.

What are the best family hotels in Otay Mesa?

For family-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG or the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, is a great option for families. It offers connecting rooms, free rollaway extra beds, and complimentary cribs, making it suitable for larger families. Guests appreciate the comfortable and clean rooms, the extremely helpful staff, and the great free buffet breakfast. Free WiFi and self-parking are also provided for added convenience. This hotel is located just 2.3 km from Amistad Park.

Another good choice is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. This hotel features a pool, connecting rooms, and a child-friendly window design. Families will also find free self-parking and complimentary grab-and-go breakfast beneficial. Guests often comment on the comfortable beds, convenient location, and friendly staff. It is situated 2.2 km from Amistad Park.

What are the best spa hotels in Otay Mesa?

For a spa hotel in Otay Mesa, the Quality Suites San Diego Otay Mesa is a suitable option.

This hotel offers accessible spa facilities and has a review rating of 7.0. Guests often mention the comfortable and clean beds, along with the convenient location. Other features include free self-parking, complimentary breakfast, free WiFi, and free toiletries.

What hotels in Otay Mesa offer free breakfast?

For hotels in Otay Mesa offering complimentary breakfast, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, provides both a free buffet breakfast and complimentary internet access. Guests frequently comment on the comfortable and clean rooms, as well as the extremely helpful and polite staff.

Another excellent option is the Quality Suites San Diego Otay Mesa, rated 7.0. This hotel offers a free breakfast, including a convenient to-go breakfast option, and complimentary self-parking. Guests appreciate the comfortable beds and the hotel's convenient location.

What are the best budget hotels in Otay Mesa?

For budget-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, rated 8.0, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. A great breakfast is included, and the hotel provides free WiFi, free toiletries, and free self-parking. It is conveniently located near Amistad Park, just 2.3 km away.

Another good option is the Quality Suites San Diego Otay Mesa, with a rating of 7.0. This hotel is commended for its comfortable and clean beds, and guests appreciate the friendly and professional staff. A good grab-and-go breakfast is provided, along with free WiFi, free toiletries, and free self-parking. It is also close to Amistad Park, at a distance of 2.2 km.

What are the most romantic hotels in Otay Mesa for couples?

For couples seeking a romantic stay in Otay Mesa, the Quality Suites San Diego Otay Mesa offers a comfortable experience.

This hotel, with a 7.0 rating, provides complimentary breakfast and free WiFi, which are convenient for couples starting their day together. Guests frequently mention the comfortable and clean beds, ensuring a pleasant night's sleep. The hotel also boasts a hot tub, great for a relaxing soak after a day of exploring. Its convenient location is often highlighted by guests.

When is the best time to go to Otay Mesa?

The best time to go to Otay Mesa is during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is typically mild and pleasant, with comfortable temperatures and less humidity than the summer. This makes it ideal for exploring the area's outdoor attractions or conducting business without the intense heat.

For business travellers, these shoulder seasons also tend to have fewer crowds compared to the peak summer months, which can make navigating the border crossings and local transportation more efficient.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa.

How much is the nightly rate at a Otay Mesa hotel?

Hotel prices in Otay Mesa often vary, but you can find a great deal from £52 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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