Otay Mesa Holidays from £901

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Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was £1,402, price is now £901 per person
£901
per person
13 May - 18 May
found 1 day ago
Return direct flight included
London (LHR) to San Diego (SAN)
8.6/10 Excellent! (1,868 reviews)
Clean, and staff super friendly and helpful!

Reviewed on 7 Apr 2026

Beach Village at The Del, LXR Hotels & Resorts

Beach Village at The Del, LXR Hotels & Resorts

5 out of 5
Historic Downtown Coronado
Save 100% on your flight
Price was £2,930, price is now £1,996 per person
£1,996
per person
13 May - 18 May
found 1 day ago
Return direct flight included
London (LHR) to San Diego (SAN)
9.2/10 Wonderful! (130 reviews)
Spectacular place. Beautiful and so much fun for the kids. The only bummer was the ocean water was contaminated and so we were not able to swim in the ocean. But the pools were amazing.

Reviewed on 5 Apr 2026

The Lodge at Torrey Pines

The Lodge at Torrey Pines

5 out of 5
Torrey Pines
Save 100% on your flight
Price was £8,541, price is now £6,224 per person
£6,224
per person
13 May - 18 May
found 1 day ago
Return direct flight included
London (LHR) to San Diego (SAN)
9.2/10 Wonderful! (913 reviews)
Staff was friendly and helpful.

Reviewed on 8 Apr 2026

The Beau Hotel Gaslamp Quarter San Diego

The Beau Hotel Gaslamp Quarter San Diego

3 out of 5
Downtown San Diego
Price was £1,637, price is now £1,210 per person
£1,210
per person
26 Jun - 30 Jun
found 1 day ago
Return direct flight included
London (LON) to San Diego (SAN)
9/10 Wonderful! (670 reviews)
Did the job for one night and my purpose

Reviewed on 7 Apr 2026

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Price was £1,631, price is now £1,221 per person
£1,221
per person
26 Jun - 30 Jun
found 1 day ago
Return direct flight included
London (LON) to San Diego (SAN)
9/10 Wonderful! (1,285 reviews)
The hotel itself is nice. Please be aware of parking fees are $70 a night. Also be aware of the Fiji water that they put in your room is $10. Also, the resort fees are $49 a night. For those who might not be aware of those fees, I just wanna be straight up about them so you are not blindsided like I was. The hotel and the staff were amazing and they are very accommodating. Our stay was nice. The hotel was very busy due to a conference so it was hard to get hot water for showers. There were days where we had to do cold showers.

Reviewed on 8 Apr 2026

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Downtown San Diego

Downtown San Diego

4 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Otay Mesa

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is £202 per night from 10 May to 11 May
£202
10 May - 11 May
includes taxes & fees
8.8/10 Excellent! (2,524 reviews)
Second time staying here and its a nice place. However, some maintenance is needed. Like faucets in showers just falling off when you turn them on. We were there with another family and their room had the exact same issue

Reviewed on 8 Apr 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is £70 per night from 20 Apr to 21 Apr
£70
20 Apr - 21 Apr
includes taxes & fees
8/10 Very Good! (3,368 reviews)
Clean rooms, worth staying here.

Reviewed on 8 Apr 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is £208 per night from 24 Apr to 25 Apr
£208
24 Apr - 25 Apr
includes taxes & fees
9/10 Wonderful! (3,516 reviews)
Property was clean. Staff were friendly and helpful. Felt the Mary Jane's restaurant was a little overrated. Food wasn’t what I expected.

Reviewed on 9 Apr 2026

Hard Rock Hotel San Diego
See all 4,885 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does an Otay Mesa travel package cost?
Discover the best of Otay Mesa from as low as £901. We offer a wonderful selection of hotels, flights and rental cars to suit every budget and style. You can score even more discounts when you add a few tours or activities to your travel package.
If I'm not able to travel, can I cancel my Otay Mesa travel package?
If your holiday plans in Otay Mesa have been upended, it's comforting to know that it is possible to cancel your booking. If you booked in the last 24 hours, you may be able to get a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may charge a fee. For more information, visit our Customer Service Portal.
How do I get a cheap travel package to Otay Mesa?
Book everything in the one place with our Otay Mesa travel packages. You'll discover bargains on flights, hotels, tours and more that'll keep your pocketbook happy and adventurous side satisfied. And, with more than 550 airlines and 1,000,000 properties across the globe to select from, you have countless opportunities to mix and match as you like.
Does Expedia offer Book Now, Pay Later Otay Mesa holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has worked out a solution to help. Now that we've partnered with online lender Klarna, it's easier than ever to book your dream getaway without drying up your savings. Klarna offers flexible payment options at checkout that take the stress out of budgeting for your break. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that suit all types of budgets, so you can take that well-deserved holiday now.
  • Pay in instalments holidays: If you'd like to pay off your getaway across multiple transactions, holidays paid in instalments might be right for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Pressing the "book now" button is easier with this payment option. Put down a small deposit on your booking and then start packing your bags.

Where should I stay in Otay Mesa?
Most who travel to Otay Mesa put both SeaWorld and San Diego Zoo on their to-do lists. Why not go for a hotel near these fantastic attractions?
What are the top hotels in Otay Mesa?
Book a stay at Manchester Grand Hyatt San Diego. It's one of this neighbourhood's most popular properties. Another top-rated option in Otay Mesa is Paradise Point Resort And Spa.
How far in advance should I book my Otay Mesa holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. A number of air carriers display prices up to 12 months prior to departure dates. This is usually the cheapest time to book. If circumstances have left you booking late, low prices to Otay Mesa occasionally appear in the weeks leading up to departure.
What does an Expedia Otay Mesa travel package include?
You can select from any combination of flights, rental cars and hotels. Once you've made your booking, you can add the fun stuff like experiences and tours. Want to pick your fare class? That's also possible. The choice is yours when it comes to crafting your perfect Otay Mesa escape.
What should I know before booking an Otay Mesa travel package?
Design deals that fit your budget with an Expedia package. Flights, hotels, rental cars — we have them all. You'll save precious cash just for bundling your bookings. Whether you're embarking on a winter snow adventure or relaxing on a sunny beach, your dream getaway is only a few clicks away.
Can I choose my airline with an Otay Mesa Expedia travel package?
With a travel package, you're the boss. Whether you'd prefer to fly to Otay Mesa in business or coach, simply pick from the available airline options. Expedia has access to over 550 partner airlines across the world.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.