Otay Mesa Travel Guide
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's entertainment choices and fascinating museums.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
Balboa Park
Culture and nature converge in this diverse park located in the heart of the city.
Things to do
Tijuana & Rosarito tour/the best tacos el yaqui
Private Full-Day Guided Tour of Tijuana
Valle de Guadalupe Gourmet Tour: Wine & Food from San Diego
Top hotels in Otay Mesa
Reviewed on 1 May 2024
Reviewed on 1 May 2024
Reviewed on 2 May 2024
Reviewed on 3 May 2024
Reviewed on 30 Apr 2024
Reviewed on 2 May 2024
Other neighbourhoods around Otay Mesa
Mid-City
While you're in Mid-City, take in top sights like Viejas Arena or Cal Coast Credit Union Open Air Theater, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and USS Midway Museum are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and Balboa Park if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Waterfront Park and Maritime Museum of San Diego. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.