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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,000 reviews)
"Friendly staff, clean room fair rates"
Canada
Mikael
The price is £87
includes taxes & fees
31 May - 1 Jun
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,743 reviews)
"great breakfast and nice staff"
United States
rosita
The price is £114
includes taxes & fees
31 May - 1 Jun
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
18.5 mi from Otay Mesa
8.2 out of 10, Very good, (1,007 reviews)
"Amazing stay"
United States
Neshaye
The price is £90
includes taxes & fees
28 May - 29 May
Crowne Plaza San Diego - Mission Valley by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
17.5 mi from Otay Mesa
8.4 out of 10, Very good, (3,545 reviews)
"Great breakfast and beautiful view!"
Canada
michelle
The price is £182
includes taxes & fees
27 May - 28 May
Sheraton San Diego Resort

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
8.5 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,001 reviews)
"Good time and stay "
United States
Ana
The price is £122
includes taxes & fees
31 May - 1 Jun
Hampton Inn & Suites Imperial Beach San Diego

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
17.7 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,945 reviews)
"Always a great stay"
United States
Jeanette
The price is £90
includes taxes & fees
26 May - 27 May
Sycuan Casino Resort

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld
2.5 star property
18.7 mi from Otay Mesa
8.2 out of 10, Very good, (97 reviews)
"The breakfast was great and I enjoyed my stay!"
United States
Felix
The price is £74
includes taxes & fees
28 May - 29 May
The Alcala Hotel Mission Valley/Seaworld

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 20.5 mi from Otay Mesa
8.6 out of 10, Excellent, (1,444 reviews)
"Great resort!"
United States
Jean-Michelle
The price is £182
includes taxes & fees
25 May - 26 May
San Diego Mission Bay Resort

Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
Bay Park, 20.9 mi from Otay Mesa
8.2 out of 10, Very good, (396 reviews)
"The rooms were great, i love the bed and the pillows, parking was easy and so was checkin"
United States
Bernadette
The price is £75
includes taxes & fees
31 May - 1 Jun
Best Western San Diego Pacific Beach/Mission Bay

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
5 mi from Otay Mesa
9.0 out of 10, Wonderful, (1,280 reviews)
"Everything was very pleasant,the place was super clean, and the breakfast was delicious👍"
United States
Nancy
The price is £98
includes taxes & fees
28 May - 29 May
Best Western Americana Inn

Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego
2.0 star property
16.8 mi from Otay Mesa
7.4 out of 10, Good, (1,673 reviews)
"It was good"
United States
Omar
The price is £66
includes taxes & fees
25 May - 26 May
Motel 6 El Cajon, CA - San Diego

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
16.6 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,661 reviews)
"This is a must stay place in San Diego"
United States
Kristi
The price is £226
includes taxes & fees
25 May - 26 May
Lafayette Hotel & Club

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 mi from Otay Mesa
9.2 out of 10, Wonderful, (3,832 reviews)
"Great resort "
United States
Ines
The price is £122
includes taxes & fees
25 May - 26 May
Best Western Plus Marina Gateway Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
8 mi from Otay Mesa
8.6 out of 10, Excellent, (1,620 reviews)
"Great stay"
United States
Helda
The price is £88
includes taxes & fees
25 May - 26 May
La Quinta Inn by Wyndham San Diego Chula Vista

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
19.5 mi from Otay Mesa
7.4 out of 10, Good, (4,232 reviews)
"Nice stay, clean room"
United States
Luis
The price is £85
includes taxes & fees
25 May - 26 May
Wyndham Garden San Diego Near SeaWorld

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
9 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,173 reviews)
"Very nice place to stay"
United States
Lingzhi
The price is £104
includes taxes & fees
25 May - 26 May
Holiday Inn Express San Diego South - Chula Vista by IHG

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
8.1 mi from Otay Mesa
8.2 out of 10, Very good, (1,515 reviews)
"Laundry room was extremely clean breakfast pretty nice staff was excellent "
United States
Victoria
The price is £86
includes taxes & fees
14 Jun - 15 Jun
Comfort Inn Chula Vista San Diego South

Comfort Inn Sea World Area

Comfort Inn Sea World Area
3.5 star property
19.1 mi from Otay Mesa
8.6 out of 10, Excellent, (3,695 reviews)
"Room is clean, staff are especially helpful and courteous, breakfast was great…all in all made my stay comfortable and convenient because just minutes away from the airport…would stay here again"
United States
Parley Vinn Anastacius
The price is £94
includes taxes & fees
25 May - 26 May
Comfort Inn Sea World Area

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
16 mi from Otay Mesa
8.4 out of 10, Very good, (6,166 reviews)
"Great place for a family vacation!"
United States
Ann
The price is £157
includes taxes & fees
7 Jun - 8 Jun
Wyndham San Diego Bayside

Best Western Yacht Harbor Hotel

Best Western Yacht Harbor Hotel
2.5 star property
18.6 mi from Otay Mesa
8.4 out of 10, Very good, (1,898 reviews)
"The rooms were well kept and the breakfast was great!"
United States
Jessica
The price is £95
includes taxes & fees
7 Jun - 8 Jun
Best Western Yacht Harbor Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What are the best hotels in Otay Mesa that travellers recommend?
Two of the best hotels in Otay Mesa that travellers recommend are the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. Visitors also highlight the great breakfast and comfortable beds. For added convenience, the hotel provides free buffet breakfast, suites, and connecting rooms, along with free rollaway extra beds and cribs. There is also an outdoor pool for relaxation.

Another highly recommended option is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. Guests consistently mention the comfortable and clean beds, the convenient location, and the friendly and professional staff. The hotel offers free breakfast, including a to-go option, along with free self-parking and accessible parking for vans, RVs, buses, and trucks.
What are the best family hotels in Otay Mesa?
For family-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG or the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, is a great option for families. It offers connecting rooms, free rollaway extra beds, and complimentary cribs, making it suitable for larger families. Guests appreciate the comfortable and clean rooms, the extremely helpful staff, and the great free buffet breakfast. Free WiFi and self-parking are also provided for added convenience. This hotel is located just 2.3 km from Amistad Park.

Another good choice is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. This hotel features a pool, connecting rooms, and a child-friendly window design. Families will also find free self-parking and complimentary grab-and-go breakfast beneficial. Guests often comment on the comfortable beds, convenient location, and friendly staff. It is situated 2.2 km from Amistad Park.
What are the best spa hotels in Otay Mesa?
For a spa hotel in Otay Mesa, the Quality Suites San Diego Otay Mesa is a suitable option.

This hotel offers accessible spa facilities and has a review rating of 7.0. Guests often mention the comfortable and clean beds, along with the convenient location. Other features include free self-parking, complimentary breakfast, free WiFi, and free toiletries.
What hotels in Otay Mesa offer free breakfast?
For hotels in Otay Mesa offering complimentary breakfast, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, provides both a free buffet breakfast and complimentary internet access. Guests frequently comment on the comfortable and clean rooms, as well as the extremely helpful and polite staff.

Another excellent option is the Quality Suites San Diego Otay Mesa, rated 7.0. This hotel offers a free breakfast, including a convenient to-go breakfast option, and complimentary self-parking. Guests appreciate the comfortable beds and the hotel's convenient location.
What are the best budget hotels in Otay Mesa?
For budget-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, rated 8.0, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. A great breakfast is included, and the hotel provides free WiFi, free toiletries, and free self-parking. It is conveniently located near Amistad Park, just 2.3 km away.

Another good option is the Quality Suites San Diego Otay Mesa, with a rating of 7.0. This hotel is commended for its comfortable and clean beds, and guests appreciate the friendly and professional staff. A good grab-and-go breakfast is provided, along with free WiFi, free toiletries, and free self-parking. It is also close to Amistad Park, at a distance of 2.2 km.
What are the most romantic hotels in Otay Mesa for couples?
For couples seeking a romantic stay in Otay Mesa, the Quality Suites San Diego Otay Mesa offers a comfortable experience.

This hotel, with a 7.0 rating, provides complimentary breakfast and free WiFi, which are convenient for couples starting their day together. Guests frequently mention the comfortable and clean beds, ensuring a pleasant night's sleep. The hotel also boasts a hot tub, great for a relaxing soak after a day of exploring. Its convenient location is often highlighted by guests.
When is the best time to go to Otay Mesa?
The best time to go to Otay Mesa is during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is typically mild and pleasant, with comfortable temperatures and less humidity than the summer. This makes it ideal for exploring the area's outdoor attractions or conducting business without the intense heat.

For business travellers, these shoulder seasons also tend to have fewer crowds compared to the peak summer months, which can make navigating the border crossings and local transportation more efficient.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa.
How can I save on a Otay Mesa hotel booking with Expedia?
Members always get our best prices. Find our best Otay Mesa hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Otay Mesa hotel?
Hotel prices in Otay Mesa often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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