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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,684 reviews)
"Great breakfast!"
United States
Susan
The price is £87
includes taxes & fees
10 May - 11 May
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,005 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is £84
includes taxes & fees
10 May - 11 May
Quality Suites San Diego Otay Mesa

Valli Hi Motel

Valli Hi Motel
2.5 star property
4.9 mi from Otay Mesa
8.4 out of 10, Very good, (1,011 reviews)
"Great location, near shops, restaurants and beaches. "
United States
Miguelina
The price is £65
includes taxes & fees
27 Apr - 28 Apr
Valli Hi Motel

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
18.5 mi from Otay Mesa
8.0 out of 10, Very good, (1,033 reviews)
"Great place to stay"
United States
Kimberly
The price is £95
includes taxes & fees
10 May - 11 May
Crowne Plaza San Diego - Mission Valley by IHG

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
16.6 mi from Otay Mesa
9.2 out of 10, Wonderful, (1,571 reviews)
"Everything about that stay was perfect"
United States
Victoria
The price is £214
includes taxes & fees
16 Apr - 17 Apr
Lafayette Hotel & Club

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
17.7 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,832 reviews)
"Awesome place "
United States
Jonathan
The price is £83
includes taxes & fees
13 Apr - 14 Apr
Sycuan Casino Resort

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
4.3 mi from Otay Mesa
8.0 out of 10, Very good, (1,581 reviews)
"Good location"
United States
Joshua
The price is £61
includes taxes & fees
12 Apr - 13 Apr
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
5 mi from Otay Mesa
9.0 out of 10, Wonderful, (1,252 reviews)
"Great place and service. Will definitely stay there again. "
United States
Maria
The price is £104
includes taxes & fees
14 Apr - 15 Apr
Best Western Americana Inn

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
8.5 mi from Otay Mesa
9.4 out of 10, Exceptional, (1,009 reviews)
"Everything was great!"
United States
Michelle
The price is £125
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Imperial Beach San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
6.5 mi from Otay Mesa
9.6 out of 10, Exceptional, (621 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
United States
Daniel
The price is £155
includes taxes & fees
3 May - 4 May
SpringHill Suites by Marriott Chula Vista Eastlake

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
17.5 mi from Otay Mesa
8.4 out of 10, Very good, (3,442 reviews)
"Nice hotel with great location "
United States
DIANA
The price is £164
includes taxes & fees
3 May - 4 May
Sheraton San Diego Resort

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 20.9 mi from Otay Mesa
8.0 out of 10, Very good, (1,223 reviews)
"Amazing def will stay again "
United States
Tanya
The price is £115
includes taxes & fees
14 Apr - 15 Apr
Ocean Villa Inn

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
10.5 mi from Otay Mesa
9.2 out of 10, Wonderful, (3,767 reviews)
"Great hotel"
United States
Deante
The price is £125
includes taxes & fees
10 May - 11 May
Best Western Plus Marina Gateway Hotel

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
19.5 mi from Otay Mesa
7.4 out of 10, Good, (4,224 reviews)
"great place"
Canada
souheil
The price is £84
includes taxes & fees
12 Apr - 13 Apr
Wyndham Garden San Diego Near SeaWorld

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 20.8 mi from Otay Mesa
8.8 out of 10, Excellent, (1,291 reviews)
"Cute place, easy location & staff was so friendly. "
United States
Ericka A
The price is £136
includes taxes & fees
28 Apr - 29 Apr
Ocean Beach Hotel

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
17.9 mi from Otay Mesa
9.2 out of 10, Wonderful, (1,062 reviews)
"Clean room, friendly staff, and only a 15 minute walk to Old Town. Also conveniently located close to the airport just a short shuttle drive away. "
United States
Olivia
The price is £121
includes taxes & fees
12 Apr - 13 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG

The Rambler Hotel

The Rambler Hotel
3.0 star property
9.2 mi from Otay Mesa
9.0 out of 10, Wonderful, (2,099 reviews)
"Great breakfast and friendly staff"
United States
Jeremy
The price is £93
includes taxes & fees
28 Apr - 29 Apr
The Rambler Hotel

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 20.5 mi from Otay Mesa
8.4 out of 10, Very good, (1,390 reviews)
"The restaurant on site was delicious "
United States
Blanca
The price is £210
includes taxes & fees
10 May - 11 May
San Diego Mission Bay Resort

Old Town Western Inn & Suites

Old Town Western Inn & Suites
2.5 star property
Old Town San Diego, 18.4 mi from Otay Mesa
7.6 out of 10, Good, (1,010 reviews)
"This hotel is in a great location. Walking distance to old town, shops and restaurants."
United States
Diane
The price is £87
includes taxes & fees
13 Apr - 14 Apr
Old Town Western Inn & Suites

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 16.6 mi from Otay Mesa
8.4 out of 10, Very good, (1,003 reviews)
"Very comfortable room and close to cool restaurants"
United States
Samantha
The price is £83
includes taxes & fees
12 Apr - 13 Apr
Berkshire Motor Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What are the best hotels in Otay Mesa that travellers recommend?
Two of the best hotels in Otay Mesa that travellers recommend are the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. Visitors also highlight the great breakfast and comfortable beds. For added convenience, the hotel provides free buffet breakfast, suites, and connecting rooms, along with free rollaway extra beds and cribs. There is also an outdoor pool for relaxation.

Another highly recommended option is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. Guests consistently mention the comfortable and clean beds, the convenient location, and the friendly and professional staff. The hotel offers free breakfast, including a to-go option, along with free self-parking and accessible parking for vans, RVs, buses, and trucks.
What are the best family hotels in Otay Mesa?
For family-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG or the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, is a great option for families. It offers connecting rooms, free rollaway extra beds, and complimentary cribs, making it suitable for larger families. Guests appreciate the comfortable and clean rooms, the extremely helpful staff, and the great free buffet breakfast. Free WiFi and self-parking are also provided for added convenience. This hotel is located just 2.3 km from Amistad Park.

Another good choice is the Quality Suites San Diego Otay Mesa, which has a 7.0 rating. This hotel features a pool, connecting rooms, and a child-friendly window design. Families will also find free self-parking and complimentary grab-and-go breakfast beneficial. Guests often comment on the comfortable beds, convenient location, and friendly staff. It is situated 2.2 km from Amistad Park.
What are the best spa hotels in Otay Mesa?
For a spa hotel in Otay Mesa, the Quality Suites San Diego Otay Mesa is a suitable option.

This hotel offers accessible spa facilities and has a review rating of 7.0. Guests often mention the comfortable and clean beds, along with the convenient location. Other features include free self-parking, complimentary breakfast, free WiFi, and free toiletries.
What hotels in Otay Mesa offer free breakfast?
For hotels in Otay Mesa offering complimentary breakfast, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, with an 8.0 rating, provides both a free buffet breakfast and complimentary internet access. Guests frequently comment on the comfortable and clean rooms, as well as the extremely helpful and polite staff.

Another excellent option is the Quality Suites San Diego Otay Mesa, rated 7.0. This hotel offers a free breakfast, including a convenient to-go breakfast option, and complimentary self-parking. Guests appreciate the comfortable beds and the hotel's convenient location.
What are the best budget hotels in Otay Mesa?
For budget-friendly accommodation in Otay Mesa, consider the Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG and the Quality Suites San Diego Otay Mesa.

The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, rated 8.0, offers comfortable and clean rooms, with guests frequently praising the extremely helpful and polite staff. A great breakfast is included, and the hotel provides free WiFi, free toiletries, and free self-parking. It is conveniently located near Amistad Park, just 2.3 km away.

Another good option is the Quality Suites San Diego Otay Mesa, with a rating of 7.0. This hotel is commended for its comfortable and clean beds, and guests appreciate the friendly and professional staff. A good grab-and-go breakfast is provided, along with free WiFi, free toiletries, and free self-parking. It is also close to Amistad Park, at a distance of 2.2 km.
What are the most romantic hotels in Otay Mesa for couples?
For couples seeking a romantic stay in Otay Mesa, the Quality Suites San Diego Otay Mesa offers a comfortable experience.

This hotel, with a 7.0 rating, provides complimentary breakfast and free WiFi, which are convenient for couples starting their day together. Guests frequently mention the comfortable and clean beds, ensuring a pleasant night's sleep. The hotel also boasts a hot tub, great for a relaxing soak after a day of exploring. Its convenient location is often highlighted by guests.
When is the best time to go to Otay Mesa?
The best time to go to Otay Mesa is during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is typically mild and pleasant, with comfortable temperatures and less humidity than the summer. This makes it ideal for exploring the area's outdoor attractions or conducting business without the intense heat.

For business travellers, these shoulder seasons also tend to have fewer crowds compared to the peak summer months, which can make navigating the border crossings and local transportation more efficient.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa.
How can I save on a Otay Mesa hotel booking with Expedia?
Members always get our best prices. Find our best Otay Mesa hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Otay Mesa hotel?
Hotel prices in Otay Mesa often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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