The Best Hotels in Otay Mesa, San Diego - 2024 Updated Prices

Other neighbourhoods around Otay Mesa

Hotels in top San Diego neighborhoods Learn more about Otay Mesa

Downtown San Diego

2 out of top 10 points of interest in this area

4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and USS Midway Museum are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

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Otay Mesa Travel Info

Location	San Diego, United States of America
Similar neighbourhoods	Central San Diego, Mission Valley West and Midway District
Number of hotels	4,468
Hotel with connecting rooms	Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Quality Suites San Diego Otay Mesa is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.

How many hotels will I find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodation options, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.