Title: The Best Hotels in Otay Mesa, San Diego - 2025 Updated Prices | Expedia.co.uk [Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Otay-Mesa.d6263723.Car-Hire-Guide)[Otay Mesa Holidays](https://expedia.co.uk/Otay-Mesa.d6263723.Holidays-City-Breaks) ![Tijuana Neighborhood Seen Over Border Fence](https://images.trvl-media.com/place/6263723/a421f2e3-03d1-46f6-89f3-1009103bee11.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Otay Mesa, San Diego ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Otay Mesa Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=PETS) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=HOTEL_RESORT) Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=APART_HOTEL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&travelerType=family_friendly) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=COTTAGE) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=OCEAN_VIEW) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=WATER_PARK) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=CONDO) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=APARTMENT) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=HOT_TUB) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=6263723&latLong=32.559475%2C-116.973465&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=POOL) ## Check prices for these dates Tonight [8 Oct - 9 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Otay Mesa, San Diego ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/673df2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/16237f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/55248c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/c6a042c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites San Diego Otay Mesa Otay Mesa 7.2/10 Good (1003) "Clean, friendly staff and yummy breakfast :)" £84 includes taxes & fees 9 Oct - 10 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/eda7e8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/1779e3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/c607b0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible, Non Smoking (Mobility, Transfer Shower) | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/1d234b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG Otay Mesa 8.0/10 Very good (1474) "Very good to stayed " £90 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/a314a493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/63587042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Gaslamp Quarter, 15.2 mi from Otay Mesa 8.8/10 Excellent (1895) "Staff was great location was great" £97 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100830000/100828000/100827985/60078fd7_edited_a626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elite Suite, 1 Queen Bed, Kitchenette | 1 bedroom](https://images.trvl-media.com/lodging/101000000/100830000/100828000/100827985/7ea5ffe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Bedrooms | 1 bedroom](https://images.trvl-media.com/lodging/101000000/100830000/100828000/100827985/b99cbba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/101000000/100830000/100828000/100827985/a01039da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zindel Little Italy, 16.1 mi from Otay Mesa 7.6/10 Good (551) "Nice place and you could walk to most places of interest " [](https://www.expedia.co.uk/San-Diego-Hotels-Hotel-Zindel.h100827985.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/e3befa7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/f3168007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter Gaslamp Quarter, 15 mi from Otay Mesa 9.0/10 Wonderful (1155) "Great stay! " £124 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/ce3fee83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/e3d5bf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/93444558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/d9883b91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horton Grand, Downtown/Gaslamp Quarter 15.1 mi from Otay Mesa 9.0/10 Wonderful (2586) "Great location and lovely staff. " [](https://www.expedia.co.uk/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/54935ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/4d9ff339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/23c18b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/ddc5f050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gaslamp Plaza Suites Gaslamp Quarter, 15.3 mi from Otay Mesa 8.8/10 Excellent (1009) "Had a great stay " £91 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Gaslamp-Plaza-Suites.h16266.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/7f3bc7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/d5ea2f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside 16 mi from Otay Mesa 8.4/10 Very good (5978) "Great stay near the airport." £152 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/d85ecd0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/60472bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/23e38216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel San Diego Gaslamp Quarter, 14.9 mi from Otay Mesa 9.0/10 Wonderful (2993) "Loved staying here. Will definitely stay again " £188 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/43298e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/b435bca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/289d71c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/f7c3fa7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Suites by Wyndham San Diego/Hotel Circle Area 17.7 mi from Otay Mesa 6.2/10 (1017) "Clean room, friendly staff" £64 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Ramada-Suites-By-Wyndham-San-Diego.h11553.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel 10.5 mi from Otay Mesa 9.2/10 Wonderful (3313) "Nice place to stay !" £117 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/4877ef6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/c517acec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/1194fa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/7bb755a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cordova Hotel on Coronado Island 14.6 mi from Otay Mesa 8.8/10 Excellent (1005) "Cute and unique hotel！" £169 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Coronado-Hotels-El-Cordova-Hotel-On-Coronado-Island.h11395.Hotel-Information) ![Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/1fbe17de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Gaslamp Quarter, 15 mi from Otay Mesa 9.4/10 Exceptional (1001) "Great staff and clean rooms" £150 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/589f8e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 2 Double Beds, Roll-in Shower, City View | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/c0dfd2f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/f8b10da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel 15.5 mi from Otay Mesa 8.4/10 Very good (1604) "Close to a lot of areas, would stay here again." £109 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/3b915004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Balcony) | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/139a6c49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/76ddbc07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/w4000h2664x0y0-982a04e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott San Diego Downtown Gaslamp Quarter Gaslamp Quarter, 15.2 mi from Otay Mesa 8.8/10 Excellent (933) "Would definitely stay again!" £139 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-AC-Hotel-By-Marriott-San-Diego-Downtown-Gaslamp-Quarter.h87137975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/5feb0059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/aeb717a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/30e922d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/7a33c92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham El Cajon/San Diego 16.7 mi from Otay Mesa 7.8/10 Good (1003) "Great place " £59 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/El-Cajon-Hotels-Super-8-By-Wyndham-El-Cajon-CA.h4926.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Café](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/a3c5905c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/423e7241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort 10.7 mi from Otay Mesa 8.8/10 Excellent (1041) "Beautiful quiet hotel." £198 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Fab) | Premium bedding, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/febc9a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/7f37543f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego 15.5 mi from Otay Mesa 8.4/10 Very good (1393) "Very nice staff from check in, clean rooms, quiet and comfortable. " £117 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/fe340c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/7012e279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/0c67e9c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds, Non Smoking | Premium bedding, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/bd7d0518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Chula Vista/San Diego 8.6 mi from Otay Mesa 6.2/10 (1012) "We feel safe and clean, the lobby service people are nice. " £58 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Chula-Vista-Hotels-Red-Roof-Inn-PLUS-Chula-Vista.h2217787.Hotel-Information) ![Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/2b01136a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/325ce31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/81f394e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/1e9b6911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego-East/El Cajon 16.9 mi from Otay Mesa 7.6/10 Good (1006) "Place was nice and comfy. Decent stay at a very genuine price. " £65 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/El-Cajon-Hotels-Days-Inn-By-Wyndham-San-Diego-EastEl-Cajon.h1175963.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23®ionId=6263723&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Otay Mesa Find the best Otay Mesa areas for the activities you enjoy most. - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, surfing and swimming](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes drinks or beverages and a beach bar](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park showing a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=177689) ## Top Otay Mesa Hotel Reviews ![Palihotel San Diego Gaslamp Quarter](//images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef_y.jpg) ### Palihotel San Diego Gaslamp Quarter 10/10 Excellent "Staff was great location was great" [](https://expedia.co.uk/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Very clean, easy to move a lot things to do and Tourist Really love it" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Sheraton San Diego Resort](//images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Amazing" [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Nice stay" [](https://expedia.co.uk/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "One of the most affordable hotels in this area and its location makes it easy to get around San Diego." [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Loved the location & ease of access to the city." [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "The soap dispenser in the shower was detached from the wall and the AC was blowing a weird smell...like wet clothes." [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![The Little Italy Hotel Downtown San Diego](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### The Little Italy Hotel Downtown San Diego 10/10 Excellent "Clean room clean bathroom staff was friendly. Wi-Fi worked easily. I would definitely book again." [](https://expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Beautiful location, close to airport and other activities. Staff was friendly and restaurant was pretty good. Nice to have the option on site. Would definitely stay here again." [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Otay Mesa? > Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is an excellent choice for families seeking comfort and convenience during their stay. This hotel offers thoughtfully designed rooms with connecting options, ensuring that families can stay close together. With amenities like free cribs and sofa beds, you can rest easy knowing that your little ones will have a cozy place to sleep at night. Guests appreciate the daily housekeeping, which provides a straightforward experience, and the complimentary buffet breakfast, superb for fueling up before a day of adventure. > > > > Another family-friendly option in Otay Mesa is [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information). Rated 7.2 by travellers, this hotel features a refreshing pool where kids can splash and play, making it a great place to unwind after a busy day. The hotel's connecting rooms and child-friendly window designs prioritize safety and comfort, ensuring that both parents and children feel at home. Additionally, the provision of free amenities for children adds extra value, making it easier for families to enjoy their stay without worrying about additional costs. ### What are the best spa hotels in Otay Mesa? > For a comfortable stay in Otay Mesa, the [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) is a solid choice, holding a review score of 7.2. This hotel provides accessible spa amenities, allowing guests to unwind and rejuvenate during their visit. ### What hotels in Otay Mesa offer free breakfast? > The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is a great choice for travellers seeking convenience and comfort. This family-friendly hotel not only offers free breakfast, including a delicious buffet, but also features spacious suites equipped with a sofa bed, making it easy to accommodate families of all sizes. Guests appreciate the outdoor pool, great for unwinding after a day of exploring, along with complimentary amenities such as toiletries, WiFi, and self-parking. With a customer review rating of 7.8, it's clear that families find value in the quality service and facilities provided. > > > > Another option in Otay Mesa is the [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information), which also offers a complimentary breakfast to start your day right. This hotel features an outdoor pool and hot tub, ideal for relaxation and family fun. The Quality Suites is particularly appealing for those requiring accessible parking and facilities, and with a review score of 7.2, it provides a comfortable experience for guests looking for extra conveniences. ### What are the best budget hotels in Otay Mesa? > The Holiday Inn Express Hotel & Suites San Diego Otay Mesa is an excellent budget-friendly option, boasting a review score of 7.8. Families will appreciate the complimentary buffet breakfast, which makes mornings easy, and the outdoor pool is superb for a refreshing dip after a day of adventures. With free Wi-Fi and spacious suites featuring sofa beds, this hotel ensures everyone has enough room to relax. Plus, the availability of cribs and rollaway beds at no extra charge makes it convenient for families traveling with little ones. > > > > Another great choice for budget-conscious travellers is the [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information), which has a review score of 7.2. This hotel offers a range of amenities geared towards families, including a free breakfast and outdoor pool, which is sure to keep kids entertained. The rooms are designed with child-friendly window features, providing peace of mind for parents. Self-parking is complimentary as well, making it easy for families to explore the local area without worrying about extra fees. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa. ### How can I save on a Otay Mesa hotel booking with Expedia? > Members always get our best prices. Find our best Otay Mesa hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Otay Mesa hotel? > Hotel prices in Otay Mesa often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. 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Airport](https://expedia.co.uk/San-Diego-Intl-Airport-Hotels.0-aSAN-0.Travel-Guide-Filter-Hotels) - [Hotels near Brown Field Municipal Airport](https://expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field Airport](https://expedia.co.uk/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Hotels near McClellan-Palomar Airport](https://expedia.co.uk/McClellan-Palomar-Airport-Hotels.0-aCLD-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Bay Club Hotel & Marina](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) - [The Dana on Mission Bay](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) - [The Sofia Hotel](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) - [Pendry San Diego](https://expedia.co.uk/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) - [Legacy Resort Hotel & Spa](https://expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) - 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