Title: The Best Hotels in Otay Mesa, San Diego - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Otay-Mesa.d6263723.Car-Hire-Guide)[Otay Mesa Holidays](https://expedia.co.uk/Otay-Mesa.d6263723.Holidays-City-Breaks) ![Tijuana Neighborhood Seen Over Border Fence](https://images.trvl-media.com/place/6263723/a421f2e3-03d1-46f6-89f3-1009103bee11.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Otay Mesa, San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Jan - 8 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6263723&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Otay Mesa hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/eda7e8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/242d8336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/a1b42446.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/1779e3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) Otay Mesa 8.0/10 Very good (1575) "Great place to stay. Really clean and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zulma £100 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) ![Free on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/bd6623c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/586d04dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/16237f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/70282182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites San Diego Otay Mesa [](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) Otay Mesa 7.2/10 Good (1010) "Clean, convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £83 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) ![3 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/22ecf276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/700997bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/08cac484.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort [](https://www.expedia.co.uk/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) 17.7 mi from Otay Mesa 9.2/10 Wonderful (1665) "Very clean resort. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Petrina [](https://www.expedia.co.uk/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/5c7cc72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/27748452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/ac267ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18970000/18961900/18961850/d6f6a325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego El Cajon [](https://www.expedia.co.uk/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) 16.4 mi from Otay Mesa 9.2/10 Wonderful (1000) "Clean, quiet, beautiful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Attia £126 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/El-Cajon-Hotels-Courtyard-By-Marriott-San-Diego-El-Cajon.h18961850.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/102000000/101350000/101340300/101340269/7991b564.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101350000/101340300/101340269/e5917959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/102000000/101350000/101340300/101340269/1fb9b89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101350000/101340300/101340269/f704cae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Chula Vista Eastlake [](https://www.expedia.co.uk/Chula-Vista-Hotels-SpringHill-Suites-By-Marriott-Chula-Vista-Eastlake.h101340269.Hotel-Information) 6.5 mi from Otay Mesa 9.6/10 Exceptional (557) "Very good stay experience!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ceabert £140 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Chula-Vista-Hotels-SpringHill-Suites-By-Marriott-Chula-Vista-Eastlake.h101340269.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/507e8c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/d573c415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/ac38c6d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19420000/19413200/19413109/d19ef2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Chula Vista [](https://www.expedia.co.uk/Chula-Vista-Hotels-Residence-Inn-By-Marriott-San-Diego-Chula-Vista.h19413109.Hotel-Information) 4.7 mi from Otay Mesa 9.4/10 Exceptional (537) "Nice hotel in a great area. Rooms & hotel were kept clean and well run. Staff was great, would definitively stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £179 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Residence-Inn-By-Marriott-San-Diego-Chula-Vista.h19413109.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/3ced364d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/69474629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/83212494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32400000/32393800/32393708/ff230e8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ayres Hotel San Diego South - Chula Vista [](https://www.expedia.co.uk/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information) 4.1 mi from Otay Mesa 9.8/10 Exceptional (1117) "Cozy room, ver nice staff and in a great location to restaurants and shopping. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda £213 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Ayres-Hotel-San-Diego-South-Chula-Vista.h32393708.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/879bd035.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/471e273e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/8c83985c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2820000/2811100/2811010/8cf8ea27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn La Mesa [](https://www.expedia.co.uk/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) 15.1 mi from Otay Mesa 7.0/10 Good (1229) "room was clean and staff very friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £46 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/La-Mesa-Hotels-Heritage-Inn-La-Mesa.h2811010.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/8da6f7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/f85548dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/8acfb37a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Suite | Premium bedding, pillow-top beds, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/470000/461200/461101/6b2cf932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamplighter Inn & Suites at SDSU [](https://www.expedia.co.uk/San-Diego-Hotels-Lamplighter-Inn-Suites-At-SDSU.h461101.Hotel-Information) 15.2 mi from Otay Mesa 9.0/10 Wonderful (1343) "Great room and rate" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly [](https://www.expedia.co.uk/San-Diego-Hotels-Lamplighter-Inn-Suites-At-SDSU.h461101.Hotel-Information) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/12700/12645/bc7617fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12700/12645/5a519562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/12700/12645/6ad23cf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/12700/12645/ddddbc6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Chula Vista/Otay Valley Hotel [](https://www.expedia.co.uk/Chula-Vista-Hotels-Best-Western-Chula-VistaOtay-Valley-Hotel.h12645.Hotel-Information) 4.4 mi from Otay Mesa 7.8/10 Good (1563) "Great relaxing stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gustavo £82 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Best-Western-Chula-VistaOtay-Valley-Hotel.h12645.Hotel-Information) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/079ae4ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/4e7175aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/bfd1ccfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/be33bca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego Chula Vista [](https://www.expedia.co.uk/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) 8 mi from Otay Mesa 8.6/10 Excellent (1499) "Everything was great, staff , Room , clean , great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £75 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) ![Outdoor pool, open 10:00 AM to 7:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/6211d6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/36da2a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/a48c362c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/18900/18870/35426640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Chula Vista San Diego South [](https://www.expedia.co.uk/Chula-Vista-Hotels-Comfort-Inn-Chula-Vista-San-Diego-South.h18870.Hotel-Information) 8.1 mi from Otay Mesa 8.2/10 Very good (1287) "Excelente hotel " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) ESTEBAN £83 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Comfort-Inn-Chula-Vista-San-Diego-South.h18870.Hotel-Information) ![Single Room, 1 King Bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/cf426036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/cebdbfb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/b510fde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/1f0a5a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Palmeras Chula Vista [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hotel-Palmeras-Chula-Vista.h57248.Hotel-Information) 8.9 mi from Otay Mesa 7.2/10 Good (2046) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bobby £51 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hotel-Palmeras-Chula-Vista.h57248.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12890000/12881700/12881670/6c2d85fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12890000/12881700/12881670/c1dfa6f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12890000/12881700/12881670/d60e8d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/13000000/12890000/12881700/12881670/752f9008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites San Diego Mission Valley [](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) 17.5 mi from Otay Mesa 9.2/10 Wonderful (1002) "Breakfast was amazing but the rooms had a smell of dog urine and the beds were horrible the most uncomfortable I ever slept in " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin Brice £118 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1664500/1664408/78d81856.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1670000/1664500/1664408/692b0ea0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1670000/1664500/1664408/4884968c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1670000/1664500/1664408/1730ccf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express San Diego South - Chula Vista by IHG [](https://www.expedia.co.uk/Chula-Vista-Hotels-Holiday-Inn-Express-San-Diego-South-Chula-Vista.h1664408.Hotel-Information) 9 mi from Otay Mesa 9.2/10 Wonderful (1003) "Clean, friendly, and the breakfast was amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ANDREW J £91 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Holiday-Inn-Express-San-Diego-South-Chula-Vista.h1664408.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/57e60275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/c9d13d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/fb95526d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/1c9bf72f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hercor Hotel - Urban Boutique [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) 8.5 mi from Otay Mesa 8.6/10 Excellent (1350) "Great staf great hotel free breakfast rooms very clean bed great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) EVA £69 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) ![Suite | Private kitchenette](https://images.trvl-media.com/lodging/11000000/10050000/10049500/10049404/39401de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/11000000/10050000/10049500/10049404/01a6e5a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/11000000/10050000/10049500/10049404/6bfe3bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/11000000/10050000/10049500/10049404/525c92ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Berkshire Motor Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Berkshire-Motor-Hotel.h10049404.Hotel-Information) North Park, 16.6 mi from Otay Mesa 8.4/10 Very good (1001) "Great spot" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexandro £68 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Berkshire-Motor-Hotel.h10049404.Hotel-Information) ![Arcade](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/ec5cea9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/4ef92902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Memory-foam beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/df9e8ced.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18300/18213/8921b04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rambler [](https://www.expedia.co.uk/Chula-Vista-Hotels-The-Rambler-Motel.h18213.Hotel-Information) 9.2 mi from Otay Mesa 9.2/10 Wonderful (2014) "Absolutely amazing stay will def be coming back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victor £84 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-The-Rambler-Motel.h18213.Hotel-Information) ![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/101000000/100160000/100159500/100159463/be5a70b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage | View from room](https://images.trvl-media.com/lodging/101000000/100160000/100159500/100159463/234546cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/101000000/100160000/100159500/100159463/fd74bcc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; pool views ](https://images.trvl-media.com/lodging/101000000/100160000/100159500/100159463/69a95fa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sun Outdoors San Diego Bay [](https://www.expedia.co.uk/Chula-Vista-Hotels-Sun-Outdoors-San-Diego-Bay.h100159463.Hotel-Information) 9.3 mi from Otay Mesa 10/10 Exceptional (82) "Loved can’t wait to stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolina £172 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Chula-Vista-Hotels-Sun-Outdoors-San-Diego-Bay.h100159463.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/025fd645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/bb54a734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Non Smoking, Refrigerator & Microwave | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/44f8822a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/2ba90811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Americana Inn [](https://www.expedia.co.uk/San-Ysidro-Hotels-Best-Western-Americana-Inn.h806327.Hotel-Information) 5 mi from Otay Mesa 9.0/10 Wonderful (1219) "Great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerald £92 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/San-Ysidro-Hotels-Best-Western-Americana-Inn.h806327.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-21&endDate=2026-01-22®ionId=6263723&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Otay Mesa Find the best Otay Mesa areas for the activities you enjoy most. - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, surfing and swimming](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes drinks or beverages and a beach bar](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park showing a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=177689) ## Top Otay Mesa Hotel Reviews ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Yes" [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "great" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Beautiful views from room 248! Great service throughout our stay from all the departments! Quiet, serenely quiet which we really enjoyed. Everything was clean, spacious, kept up and easy to navigate." [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "We have stayed here before and it’s always amazing " [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "The room was nice, clean, and quiet. " [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Breakfast is good " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Marriott Marquis San Diego Marina](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "The room was great, great views of the city and marina. Location is great. Overall I’d recommend this hotel. Brought my girl for a weekend getaway and we both loved it. " [](https://expedia.co.uk/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Staff was friendly and we were able to check in early without a problem. Room is clean and shower is great!" [](https://expedia.co.uk/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Customer Service at front desk. I was able to check in early." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Otay Mesa? > Another family-friendly option in Otay Mesa is [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information). Rated 7.2 by travellers, this hotel features a refreshing pool where kids can splash and play, making it a great place to unwind after a busy day. The hotel's connecting rooms and child-friendly window designs prioritize safety and comfort, ensuring that both parents and children feel at home. Additionally, the provision of free amenities for children adds extra value, making it easier for families to enjoy their stay without worrying about additional costs. ### What are the best spa hotels in Otay Mesa? ### What hotels in Otay Mesa offer free breakfast? > Another option in Otay Mesa is the [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information), which also offers a complimentary breakfast to start your day right. This hotel features an outdoor pool and hot tub, ideal for relaxation and family fun. The Quality Suites is particularly appealing for those requiring accessible parking and facilities, and with a review score of 7.2, it provides a comfortable experience for guests looking for extra conveniences. ### What are the best budget hotels in Otay Mesa? > Another great choice for budget-conscious travellers is the [Quality Suites San Diego Otay Mesa](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information), which has a review score of 7.2\. This hotel offers a range of amenities geared towards families, including a free breakfast and outdoor pool, which is sure to keep kids entertained. The rooms are designed with child-friendly window features, providing peace of mind for parents. Self-parking is complimentary as well, making it easy for families to explore the local area without worrying about extra fees. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Otay Mesa hotel booking with Expedia? ### How much is the nightly rate at a Otay Mesa hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Atlantis Laser Tag ](https://www.expedia.co.uk/Atlantis-Laser-Tag-Hotels.0-l553248621532638600-0.Travel-Guide-Filter-Hotels) - [Bonita Hotels ](https://www.expedia.co.uk/Bonita-Hotels.d177687.Travel-Guide-Hotels) - [Hotels near Brown Field Municipal ](https://www.expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Chula Vista Hotels ](https://www.expedia.co.uk/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels) - [Dulzura Hotels ](https://www.expedia.co.uk/Dulzura-Hotels.d3000427615.Travel-Guide-Hotels) - [Emerald Hills Hotels ](https://www.expedia.co.uk/Emerald-Hills-San-Diego-Hotels.0-n797413919713509376-0.Travel-Guide-Filter-Hotels) - 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