Title: Hotels in Mayo River - Best Mayo River Hotels from £51 - Fully Refundable Options - Expedia.co.uk [Mayo River Travel Guide](https://expedia.co.uk/Mayo-River.dx553248635976006279)[Holiday Rentals in Mayo River](https://expedia.co.uk/Mayo-River-Holiday-Rentals.d553248635976006279.Travel-Guide-HolidayRentals)[Flights to Mayo River](https://expedia.co.uk/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[Mayo River Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mayo-River.d553248635976006279.Car-Hire-Guide)[Mayo River Holidays](https://expedia.co.uk/Mayo-River.d553248635976006279.Holidays-City-Breaks) ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ed Mayfield # Find hotels in Mayo River, VA from £51 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Mayo River Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=APARTMENT) Farm [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=AGRITOURISM) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=CABIN) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=PETS) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Mayo+River%2C+Virginia%2C+United+States+of+America®ionId=553248635976006279&latLong=36.63869%2C-80.126018&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=COTTAGE) ## Check prices for these dates Tonight [2 Nov - 3 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976006279&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Nov - 4 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976006279&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976006279&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976006279&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Mayo River hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/d7ce6da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Tree House, 1 King Bed (Barn Owl, Adults Only) | Premium bedding, in-room safe, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/ef77317a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Tree House, 1 King Bed (Cooper's Hawk, Adults Only) | Premium bedding, in-room safe, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/0892b487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/84ebd106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Primland, Auberge Collection Meadows Of Dan 9.0/10 Wonderful (24) "By far the best stay at a resort we’ve had. Everything about our experience was phenomenal from our room, to the views, food, amenities, excursions, and customers service. We were blown away by the warmth and friendliness of the staff. They were very accommodating and made our experience even more enjoyable. We didn’t want to leave! This will be an annual spot for our family to return to. Worth every penny! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily £507 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Meadows-Of-Dan-Hotels-The-Lodge-At-Primland.h3633184.Hotel-Information) ![Double Room, 2 Double Beds, Non Smoking | Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/30ed950c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/9c1ae94c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/e38bf22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Eden Eden 8.6/10 Excellent (543) "Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krista £71 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/35d81c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/ef81763d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/0f261a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/04e1ce3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Ridgeway Martinsville Area Ridgeway 6.6/10 (187) "Nice place. Would return" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet L. £58 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/9373a79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/23224694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/0c10463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/053c1303.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Martinsville Martinsville 6.4/10 (472) "It's been my husband and my spot to get away from home for a little time to ourselves." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ericka £51 includes taxes & fees 15 Nov - 16 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/bcacb4e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/fc4390ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/27086093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Eden Eden 8.6/10 Excellent (429) "We have stayed here twice now, easy to get to, parking is good, place is clean and staff is friendly and helpful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £97 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/ee448a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/9e55a796.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/9f72338d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Non Smoking | Individually furnished, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/160000/154800/154773/25a4e0d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scottish Inns Collinsville-Martinville Collinsville 6.8/10 (273) "I liked everything about the place I really enjoyed my stay hoping to revisit " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ruhia £42 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-Scottish-Inns-Collinsville-Martinville.h154773.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/d7bc649f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/e47dfbbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/a6854b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | In-room dining](https://images.trvl-media.com/lodging/96000000/95840000/95832200/95832103/8456d7a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn Ridgeway 6.0/10 (54) "Close to race track" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda [](https://www.expedia.co.uk/Ridgeway-Hotels-4520-Greensboro-Rd.h95832103.Hotel-Information) ![Deluxe Room | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e5c62df7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/c6320945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e6cbb0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/37620728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Floyd Floyd 9.6/10 Exceptional (485) "Room was very clean and beds were very comfortable. Breakfast was awesome! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeannine £101 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/df0b8433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/a70ec908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/94618658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Martinsville Martinsville 8.8/10 Excellent (482) "Very nice stay even for short stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jack £143 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/f1861bf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/1128badc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/6c395224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/bad88172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tuggle's Gap Roadside Inn - Blue Ridge Parkway Floyd 9.4/10 Exceptional (151) "Easy contacless check-in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chrysallis [](https://www.expedia.co.uk/Floyd-Hotels-Tuggles-Gap-Roadside-Inn.h89174849.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/5f79a23d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Crescent Moon Room | Living area](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/a74928f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Crescent Moon Room | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/c4a1338d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/6cec13e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonlight Manor Bed and Breakfast Floyd 10/10 Exceptional (37) "Jenny was a wonderful host. Really enjoyed my stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean £151 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Floyd-Hotels-Moonlight-Manor-Bed-And-Breakfast.h100143353.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/12c53bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Suite, 1 Queen Bed, Non Smoking | 1 bedroom, premium bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/70ccfa2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/1caba1ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared kitchen](https://images.trvl-media.com/lodging/17000000/16110000/16104100/16104080/aee5ccde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hunter House Bed and Breakfast Madison 9.4/10 Exceptional (35) "My dog, Chica, and I had a lovely visit at this delightful bed and breakfast. The breakfast was delicious both mornings. The house is lovely and is an easy walk to the downtown area. We will definitely be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth £144 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Reidsville-Hotels-Hunter-House-Bed-And-Breakfast.h16104080.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![56-inch TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/f05e692b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/33d9301a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/a762e12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Martinsville Martinsville 6.8/10 (610) "Convenient location, average breakfast. 1st room we were given the lights in the bathroom didn't work, got a second room and the door lock wouldn't work, got a third room and some of the lights didn't work but we stayed because we were exhausted. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha £84 includes taxes & fees 27 Nov - 28 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-Baymont-By-Wyndham-Martinsville.h665072.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/796ec9c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, towels](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/e9f8e260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/0412020c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/4aeb503b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eden Inn Motel Eden 6.4/10 (181) "It was clean an quiet exactly what we were looking for " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) isabella £53 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/ca5d4730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/613f6b69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Individually furnished, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/83cc02c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Single Room | Bathroom | Towels](https://images.trvl-media.com/lodging/96000000/95010000/95002100/95002016/72a9b326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Virginian Motel Stuart 6.2/10 (54) "Overnighted on a recent motorcycle trip. Front desk staff was very helpful helping me get the tv going " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven [](https://www.expedia.co.uk/Stuart-Hotels-Virginian-Motel.h95002016.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/63dda0e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | 1 bedroom, Egyptian cotton sheets, premium bedding, memory-foam beds](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/w1199h799x1y1-cc2949d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/w1175h799x1y1-03963b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/92000000/91330000/91324500/91324436/w1199h799x1y1-df9c8350.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Oakdale Inn Martinsville 9.8/10 Exceptional (18) "Beautiful house, great hostess and excellent breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £126 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/Martinsville-Hotels-The-Oakdale-Inn.h91324436.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/0877213b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/bf6b92bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Studio, Non Smoking | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/bcbb093c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/05f9fe93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax Inn Collinsville 6.0/10 (23) "The stay was nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £42 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Collinsville-Hotels-Relax-Inn.h101226990.Hotel-Information) ![House | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/00f6ddd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | Living area | 65-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/b10eb37b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/6f7f10dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112770000/112765400/112765345/5bca12d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### King Bed Pet Friendly BBQ Grill Peaceful Madison 8.0/10 Very good (1) £376 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Madison-Hotels-King-Bed-Pet-Friendly-BBQ-Grill-Peaceful.h112765345.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=553248635976006279&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels) ## Stay near popular Virginias attractions [](https://www.expedia.co.uk/Reynolds-Homestead-Hotels.0-l553248621561864249-0.Travel-Guide-Filter-Hotels) ### Reynolds Homestead You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forests or visit its spas. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561864249) ## Learn more about Mayo River Head to sights like Reynolds Homestead as you discover the local area in Mayo River. [See all hotels in Mayo River](https://www.expedia.co.uk/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17&adults=2®ionId=553248635976006279) ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=899&h=675&p=1&q=high) Photo by Ed Mayfield ## Top Mayo River Hotel Reviews ![Baymont by Wyndham Eden](//images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_y.jpg) ### Baymont by Wyndham Eden 10/10 Excellent "Quiet, location, clean and nice complementary breakfast. Would visit again" [](https://expedia.co.uk/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Moonlight Manor Bed and Breakfast](//images.trvl-media.com/lodging/101000000/100150000/100143400/100143353/5f79a23d_y.jpg) ### Moonlight Manor Bed and Breakfast 10/10 Excellent "This is an amazing place. Very relaxing. Just stayed for an overnight, but enjoyed it immensely. Every need was anticipated, the room was cozy, well appointed, and the bed was beyond comfortable. The couple who run the Manor are extremely friendly and welcoming. I would recommend this for a relaxing getaway at any time." [](https://expedia.co.uk/Floyd-Hotels-Moonlight-Manor-Bed-And-Breakfast.h100143353.Hotel-Information) ![Hotel Floyd](//images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e5c62df7_y.jpg) ### Hotel Floyd 10/10 Excellent "Convenient to everything Floyd!" [](https://expedia.co.uk/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) ![Eden Inn Motel](//images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/796ec9c2_y.jpg) ### Eden Inn Motel 10/10 Excellent "Relaxing " [](https://expedia.co.uk/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) ![Tuggle's Gap Roadside Inn - Blue Ridge Parkway](//images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/f1861bf5_y.jpg) ### Tuggle's Gap Roadside Inn - Blue Ridge Parkway 10/10 Excellent "Check in was smooth. Room is clean. Breakfast is very good but start from 8am." [](https://expedia.co.uk/Floyd-Hotels-Tuggles-Gap-Roadside-Inn.h89174849.Hotel-Information) ![Hampton Inn Martinsville](//images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a_y.jpg) ### Hampton Inn Martinsville 10/10 Excellent "Pet friendly and perfect temperature!!" [](https://expedia.co.uk/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ![Hampton Inn Eden](//images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500_y.jpg) ### Hampton Inn Eden 10/10 Excellent "It was clean and comfy. The toilet clogged up and the front desk staff immediately came and fixed it. I would stay here again!" [](https://expedia.co.uk/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Comfort Inn](//images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7_y.jpg) ### Comfort Inn 8/10 Good "Nice staff" [](https://expedia.co.uk/Martinsville-Hotels-Baymont-By-Wyndham-Martinsville.h665072.Hotel-Information) ![Relax Inn](//images.trvl-media.com/lodging/102000000/101230000/101227000/101226990/0877213b_y.jpg) ### Relax Inn 10/10 Excellent "Good motel. Nice service." [](https://expedia.co.uk/Collinsville-Hotels-Relax-Inn.h101226990.Hotel-Information) ## More cheap stays in Mayo River ![Baymont by Wyndham Eden](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Eden 716 Linden Dr, Eden, NC £71 23 Nov - 24 Nov includes taxes & fees 8.4/10 Very Good! (538 reviews) [](https://expedia.co.uk/Reidsville-Hotels-Baymont-By-Wyndham-Eden.h570926.Hotel-Information) ![Hampton Inn Martinsville](https://images.trvl-media.com/lodging/1000000/50000/43100/43095/c2d0654a_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Martinsville 50 Hampton Dr, Martinsville, VA £143 16 Nov - 17 Nov includes taxes & fees 8.8/10 Excellent! (482 reviews) [](https://expedia.co.uk/Martinsville-Hotels-Hampton-Inn-Martinsville.h43095.Hotel-Information) ![Hotel Floyd](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e5c62df7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Floyd 300 Rick Lewis Way, Floyd, VA £101 3 Nov - 4 Nov includes taxes & fees 9.6/10 Exceptional! (484 reviews) [](https://expedia.co.uk/Floyd-Hotels-Hotel-Floyd.h8986854.Hotel-Information) ![Econo Lodge](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/9373a79c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Econo Lodge 1755 Virginia Ave, Martinsville, VA £51 15 Nov - 16 Nov includes taxes & fees 6.4/10 (471 reviews) [](https://expedia.co.uk/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information) ![Hampton Inn Eden](https://images.trvl-media.com/lodging/1000000/50000/42800/42735/f228f500_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Eden 724 S Van Buren Rd, Eden, NC £97 23 Nov - 24 Nov includes taxes & fees 8.6/10 Excellent! (427 reviews) [](https://expedia.co.uk/Reidsville-Hotels-Hampton-Inn-Eden.h42735.Hotel-Information) ![Eden Inn Motel](https://images.trvl-media.com/lodging/13000000/12770000/12764600/12764520/796ec9c2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Eden Inn Motel 213 S Van Buren Rd, Eden, NC £53 4 Nov - 5 Nov includes taxes & fees 6.4/10 (180 reviews) [](https://expedia.co.uk/Reidsville-Hotels-Eden-Inn-Motel.h12764520.Hotel-Information) ## Hotels in Mayo River with star rating ![5 Star Hotels](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/d7ce6da6_w.jpg) 5 Star Hotels 1 properties [](https://expedia.co.uk/5Star-Mayo-River-Hotels.s50-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/90000000/89180000/89174900/89174849/f1861bf5_w.jpg) 4 Star Hotels 1 properties [](https://expedia.co.uk/4Star-Mayo-River-Hotels.s40-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7_w.jpg) 3 Star Hotels 23 properties [](https://expedia.co.uk/3Star-Mayo-River-Hotels.s30-0-d553248635976006279.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/580000/571000/570926/34cebbf3_w.jpg) 2 Star Hotels 26 properties [](https://expedia.co.uk/2Star-Mayo-River-Hotels.s20-0-d553248635976006279.Travel-Guide-Filter-Hotels) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [5 Star Hotels in Ridgeway](https://www.expedia.co.uk/5Star-Ridgeway-Hotels.s50-0-d184106.Travel-Guide-Filter-Hotels) - [Ararat Hotels](https://www.expedia.co.uk/Ararat-Hotels.d6132850.Travel-Guide-Hotels) - [Axton Hotels](https://www.expedia.co.uk/Axton-Hotels.d6351116.Travel-Guide-Hotels) - [Burks Fork Hotels](https://www.expedia.co.uk/Burks-Fork-Hotels.d553248635976006694.Travel-Guide-Hotels) - [Cana Hotels](https://www.expedia.co.uk/Cana-Hotels.d6135661.Travel-Guide-Hotels) - [Check Hotels](https://www.expedia.co.uk/Check-Hotels.d553248635975850774.Travel-Guide-Hotels) - [Claudville Hotels](https://www.expedia.co.uk/Claudville-Hotels.d6353578.Travel-Guide-Hotels) - [Collinsville Hotels](https://www.expedia.co.uk/Collinsville-Hotels.d6579.Travel-Guide-Hotels) - [Dugspur Hotels](https://www.expedia.co.uk/Dugspur-Hotels.d6351097.Travel-Guide-Hotels) - [Fancy Gap Hotels](https://www.expedia.co.uk/Fancy-Gap-Hotels.d103320.Travel-Guide-Hotels) - [Ferrum Hotels](https://www.expedia.co.uk/Ferrum-Hotels.d6351123.Travel-Guide-Hotels) - [Fieldale Hotels](https://www.expedia.co.uk/Fieldale-Hotels.d3000459947.Travel-Guide-Hotels) - [Floyd Hotels](https://www.expedia.co.uk/Floyd-Hotels.d6131163.Travel-Guide-Hotels) - [Henry Hotels](https://www.expedia.co.uk/Henry-Hotels.d821873061226737664.Travel-Guide-Hotels) - [Hotels with Indoor Pools in Martinsville](https://www.expedia.co.uk/Martinsville-Hotels-Hotels-With-Indoor-Pools.0-0-d6056947-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Martinsville Hotels](https://www.expedia.co.uk/Martinsville-Hotels.d6056947.Travel-Guide-Hotels) - [Adults Only Resorts & in Meadows Of Dan](https://www.expedia.co.uk/Meadows-Of-Dan-Hotels-Adults-Only-Resorts.0-0-d6131978-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Meadows Of Dan Hotels](https://www.expedia.co.uk/Meadows-Of-Dan-Hotels.d6131978.Travel-Guide-Hotels) - [Patrick Springs Hotels](https://www.expedia.co.uk/Patrick-Springs-Hotels.d3000460602.Travel-Guide-Hotels) - [Penhook Hotels](https://www.expedia.co.uk/Penhook-Hotels.d3000355243.Travel-Guide-Hotels) - [Pilot Hotels](https://www.expedia.co.uk/Pilot-Hotels.d3000460609.Travel-Guide-Hotels) - [Apartments in Pine Creek](https://www.expedia.co.uk/Pine-Creek-Apartments.d553248635976006760-aaApartments.Travel-Guide-Accommodation) - [Chalets in Pine Creek](https://www.expedia.co.uk/Pine-Creek-Chalets.d553248635976006760-aaChalets.Travel-Guide-Accommodation) - [Hotels with Pool in Pine Creek](https://www.expedia.co.uk/Pine-Creek-Hotels-Hotels-With-Pool.0-0-d553248635976006760-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Pine Creek](https://www.expedia.co.uk/Pine-Creek-Hotels-Motel-6.0-0-d553248635976006760--bMotel6.Travel-Guide-Filter-Hotels) - [Villas in Pine Creek](https://www.expedia.co.uk/Pine-Creek-Villas.d553248635976006760-aaVillas.Travel-Guide-Accommodation) - [Hotels near Richard P. 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[Stuart Hotels](https://www.expedia.co.uk/Stuart-Hotels.d6136643.Travel-Guide-Hotels) - [Vesta Hotels](https://www.expedia.co.uk/Vesta-Hotels.d3000355325.Travel-Guide-Hotels) - [Villa Heights Hotels](https://www.expedia.co.uk/Villa-Heights-Hotels.d553248634998668089.Travel-Guide-Hotels) - [Willis Hotels](https://www.expedia.co.uk/Willis-Hotels.d3000007816.Travel-Guide-Hotels) - [Wirtz Hotels](https://www.expedia.co.uk/Wirtz-Hotels.d184123.Travel-Guide-Hotels) - [Woolwine Hotels](https://www.expedia.co.uk/Woolwine-Hotels.d6050692.Travel-Guide-Hotels) - [Flights to Ararat](https://www.expedia.co.uk/Cheap-Flights-To-Ararat.d6132850.Travel-Guide-Flights) - [Flights to Axton](https://www.expedia.co.uk/Cheap-Flights-To-Axton.d6351116.Travel-Guide-Flights) - [Flights to Hillsville](https://www.expedia.co.uk/Cheap-Flights-To-Hillsville.d6056937.Travel-Guide-Flights) - [Flights to Martinsville](https://www.expedia.co.uk/Cheap-Flights-To-Martinsville.d6056947.Travel-Guide-Flights) - [Flights to Pilot](https://www.expedia.co.uk/Cheap-Flights-To-Pilot.d3000460609.Travel-Guide-Flights) - 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[Floyd Farmers Market](https://www.expedia.co.uk/Floyd-Farmers-Market-Floyd.d553248621532658010.Attraction) - [Floyd Holidays](https://www.expedia.co.uk/Floyd.d6131163.Holidays-City-Breaks) - [Fred Clifton Park](https://www.expedia.co.uk/Fred-Clifton-Park-Stuart.d553248621561864446.Attraction) - [Martinsville Holidays](https://www.expedia.co.uk/Martinsville.d6056947.Holidays-City-Breaks) - [Visit Penhook](https://www.expedia.co.uk/Penhook.dx3000355243) - [Pilot Holidays](https://www.expedia.co.uk/Pilot.d3000460609.Holidays-City-Breaks) - [Primland Resort Golf Course](https://www.expedia.co.uk/Primland-Resort-Golf-Course-Meadows-Of-Dan.d553248621532658004.Attraction) - [Richard P. Gravely Jr. Nature Preserve](https://www.expedia.co.uk/Richard-P-Gravely-Jr-Nature-Preserve-Ridgeway.d553248621561864251.Attraction) - [Visit Sanville](https://www.expedia.co.uk/Sanville.dx553248635975855580) - [Southwestern Virginia Holidays](https://www.expedia.co.uk/Southwestern-Virginia.d6056922.Holidays-City-Breaks) - [Visit Southwestern Virginia](https://www.expedia.co.uk/Southwestern-Virginia.dx6056922) - [Visit Stanleytown](https://www.expedia.co.uk/Stanleytown.dx3000355293) - [Vesta Holidays](https://www.expedia.co.uk/Vesta.d3000355325.Holidays-City-Breaks) - [Willis Holidays](https://www.expedia.co.uk/Willis.d3000007816.Holidays-City-Breaks) - [Auto Rent Rental Cars in Dan River](https://www.expedia.co.uk/Auto-Rent-Car-Rentals-In-Dan-River.d553248635976006277-c1006.Car-Rental-Guide-Suppliers) - [Car hire Floyd](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Floyd.d6131163.Car-Hire-Guide) - [Car hire Pilot](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Pilot.d3000460609.Car-Hire-Guide) - [Car hire Rocky Mount](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Rocky-Mount.d9621.Car-Hire-Guide) - [Car hire Stuart](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Stuart.d6136643.Car-Hire-Guide) - [Firefly EU Rental Cars in Peters Creek](https://www.expedia.co.uk/Firefly-EU-Car-Rentals-In-Peters-Creek.d553248635976006278-c1054.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Southwestern Virginia](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Southwestern-Virginia.d6056922-c40.Car-Rental-Guide-Suppliers) - [Offer Car Hire Rental Cars in Meadows Of Dan](https://www.expedia.co.uk/Offer-Car-Hire-Car-Rentals-In-Meadows-Of-Dan.d6131978-c1141.Car-Rental-Guide-Suppliers) - [Patrick Springs Holiday Rentals](https://www.expedia.co.uk/Patrick-Springs-Holiday-Rentals.d3000460602.Travel-Guide-HolidayRentals) - [Penhook Holiday Rentals](https://www.expedia.co.uk/Penhook-Holiday-Rentals.d3000355243.Travel-Guide-HolidayRentals) - [Pilot Holiday Rentals](https://www.expedia.co.uk/Pilot-Holiday-Rentals.d3000460609.Travel-Guide-HolidayRentals) - [Southwestern Virginia Holiday Rentals](https://www.expedia.co.uk/Southwestern-Virginia-Holiday-Rentals.d6056922.Travel-Guide-HolidayRentals) - [Book Hotels in Mayo River on Expedia.com](https://www.expedia.com/Mayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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