Title: Mayo River Travel Guide: Best of Mayo River, Virginia Travel 2026 | Expedia.co.uk [Hotels in Mayo River](https://expedia.co.uk/Mayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[Holiday Rentals in Mayo River](https://expedia.co.uk/Mayo-River-Holiday-Rentals.d553248635976006279.Travel-Guide-HolidayRentals)[Flights to Mayo River](https://expedia.co.uk/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[Mayo River Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mayo-River.d553248635976006279.Car-Hire-Guide)[Mayo River Holidays](https://expedia.co.uk/Mayo-River.d553248635976006279.Holidays-City-Breaks) # Mayo River Travel Guide ## Tourist Guide ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Beautiful catalpa tree that is on the grounds of the Reynolds Homestead, birthplace of RJ Reynolds of the tobacco company.](https://images.trvl-media.com/place/553248621561864249/24325db3-9033-45ce-a7cd-75f101c1fad1.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Mayo River Things to do - Top hotels in Mayo River - Top Holiday Rentals in Mayo River ![The Lodge at Primland, Auberge Collection](https://images.trvl-media.com/lodging/4000000/3640000/3633200/3633184/d7ce6da6_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Lodge at Primland, Auberge Collection 2000 Busted Rock Rd Meadows Of Dan VA £394 18 Feb - 19 Feb includes taxes & fees Stay at this luxury lodge in Meadows Of Dan. Enjoy free Wi-Fi, free parking and a full-service spa. Popular attractions Lovers Leap Scenic Overlook and Fred ... 9/10 Wonderful! (25 reviews) The resort is an experience. The staff were helpful and genuine. Reviewed on 9 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F02%2F2026&endDate=19%2F02%2F2026&selected=3633184&PinnedHotelID=3633184&HadPinnedHotel=true®ionId=553248635976006279) ![Comfort Inn Martinsville](https://images.trvl-media.com/lodging/1000000/670000/665100/665072/5a1d33a7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn Martinsville 378 Commonwealth Blvd W Martinsville VA £86 15 Feb - 16 Feb includes taxes & fees Stay at this business-friendly hotel in Martinsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ... 6.8/10 (628 reviews) Hotel was clean room was nice and smelt clean. Wake up call service was having a problem unable to use that service and the front door was having an issue, but the hotel was clean, and the breakfast was good Reviewed on 23 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=15%2F02%2F2026&endDate=16%2F02%2F2026&selected=665072&PinnedHotelID=665072&HadPinnedHotel=true®ionId=553248635976006279) ![Hotel Floyd](https://images.trvl-media.com/lodging/9000000/8990000/8986900/8986854/e5c62df7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Floyd 300 Rick Lewis Way Floyd VA £89 2 Feb - 3 Feb includes taxes & fees Stay at this business-friendly hotel in Floyd. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ... 9.6/10 Exceptional! (492 reviews) Clean, polite and helpful staff. Reviewed on 6 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=8986854&PinnedHotelID=8986854&HadPinnedHotel=true®ionId=553248635976006279) [See all 270 properties in Mayo River](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=02%2F02%2F2026&endDate=03%2F02%2F2026®ionId=553248635976006279) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Large, Stunning Cabin with Breathtaking View of Piedmont, Pilot Mountain](https://images.trvl-media.com/lodging/28000000/27140000/27134700/27134693/c5b7be21_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Large, Stunning Cabin with Breathtaking View of Piedmont, Pilot Mountain Hillsville VA Stay at this family-friendly cabin in Hillsville. Enjoy laundry facilities, patios and in-room jetted baths. Popular attractions Olde Mill Golf Resort and Primland ... 10/10 Exceptional! (196 reviews) Cozy and clean Reviewed on 10 Nov 2025 [](https://expedia.co.uk/Hillsville-Hotels-Large.h27134693.Hotel-Information) ![A-frame Cabin at Hanging Rock](https://images.trvl-media.com/lodging/67000000/66800000/66792700/66792610/1804256f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### A-frame Cabin at Hanging Rock Danbury NC Stay at this cabin in Danbury. Enjoy free Wi-Fi, a garden and patios. Popular attractions The Dan River Company and Hanging Rock State Park are located ... 9.8/10 Exceptional! (74 reviews) Good time! Once we got the code to check in was easy. The kitchen and the entire cabin was very clean. Reviewed on 7 Aug 2025 [](https://expedia.co.uk/Danbury-Hotels-A-Frame-Cabin-At-Hanging-Rock.h66792610.Hotel-Information) ![Mill & Waterfall: "Top 23 Airbnb's in NC" with Hot Tub!](https://images.trvl-media.com/lodging/36000000/35530000/35525700/35525687/b1719558_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Mill & Waterfall: "Top 23 Airbnb's in NC" with Hot Tub! Westfield NC Stay at this holiday home in Westfield. Enjoy a garden, laundry facilities and patios. Popular attraction Hart's Access is located nearby. 9.6/10 Exceptional! (71 reviews) We feel fortunate to have found this piece of preserved history and enjoyed all that the Mill House offers. Peaceful, private, comfortable, clean and close to Hanging Rock. Wonderful family adventure! Reviewed on 27 Nov 2025 [](https://expedia.co.uk/Westfield-Hotels-Mill-Waterfall-Mt-AiryHng-RckPlt-MtnHotTub.h35525687.Hotel-Information) [See all properties in Mayo River](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635976006279&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Mayo River hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=2026-02-01&endDate=2026-02-02)[1 Feb - 2 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=2026-02-01&endDate=2026-02-02) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=2026-02-02&endDate=2026-02-03)[2 Feb - 3 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=2026-02-02&endDate=2026-02-03) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026)[6 Feb - 8 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635976006279&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026) ### Popular places to visit ![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Reynolds Homestead You can study the exhibits at Reynolds Homestead, a museum with a story of its own, during your travels to Patrick Springs. Amble around the area's forests or visit its spas. 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Gravely Jr. Nature Preserve ](https://expedia.co.uk/Richard-P-Gravely-Jr-Nature-Preserve-Ridgeway.d553248621561864251.Attraction) - [Fred Clifton Park ](https://expedia.co.uk/Fred-Clifton-Park-Stuart.d553248621561864446.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app