Santa Croce Travel Guide

Florence

A bustling European square with historic buildings, shops, and a prominent clock tower.
A detailed stone facade of a historical building with intricate carvings and statues.
A statue of a woman in a robe and a building with Gothic architecture.
A detailed wooden door with carvings of a woman, a man, and a shield.
A historic church with ornate architecture and a crowd of people in front.

Stay near popular Santa Croce attractions

A historic square with a prominent church in the center, surrounded by old buildings and a cobblestone pavement.

Piazza Santa Croce

8.8/5 (12 reviews)
You can learn about the history of Florence when you stop by Piazza Santa Croce. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
See properties

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£25
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Small-Group Wine Tasting Experience in the Tuscan Countryside

Small-Group Wine Tasting Experience in the Tuscan Countryside

£77
per adult
98% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

£30
per adult
88% of travellers recommend
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

£17
per adult
82% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
People riding scooters in Tuscany

Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine

£96
per adult
100% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Florence half day combo tour with David, Uffizi & Duomo

Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option

£30
per adult
92% of travellers recommend
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
See all activities in Florence

Top hotels in Santa Croce

Aurum Uffizi

Aurum Uffizi

4 out of 5
Via Osteria Del Guanto 6 Florence FI
The price is £215 per night from 26 Jul to 27 Jul
£215
26 Jul - 27 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their reviews. ...
7.6/10 Good! (1,003 reviews)
"Great location, modern, clean and comfortable"

Reviewed on 21 Jun 2026

Aurum Uffizi
Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

4 out of 5
Lungarno Della Zecca Vecchia 38 Florence FI
The price is £219 per night from 27 Jul to 28 Jul
£219
27 Jul - 28 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free Wi-Fi, an outdoor pool and a rooftop terrace. Our guests praise the helpful staff and the property condition in their ...
9.4/10 Exceptional! (1,000 reviews)
"great location. great staff."

Reviewed on 26 Jun 2026

Plaza Hotel Lucchesi
FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo

4 out of 5
Lungarno del Tempio, 44 Florence FI
The price is £119 per night from 11 Jul to 12 Jul
£119
11 Jul - 12 Jul
includes taxes & fees
Stay at this family-friendly hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. ...
8.2/10 Very good! (1,001 reviews)
"Overall, the hotel is clean. The staff team were very helpful and friendly. We stayed at a triple room for a family of 3 in late June. The size of room was a bit small but comfy. AC’s powerful. The location is convenient and quiet, about 20-25 min walk along the river to city center. The hotel parking ..."

Reviewed on 25 Jun 2026

FH55 Grand Hotel Mediterraneo
Hotel Balestri

Hotel Balestri

4 out of 5
Piazza Mentana 7 Florence FI
The price is £193 per night from 19 Jul to 20 Jul
£193
19 Jul - 20 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free Wi-Fi, a rooftop terrace and valet parking (surcharge). Our guests praise the breakfast and the helpful staff in their ...
9.4/10 Exceptional! (1,004 reviews)
"Beautiful and elegant hotel in a perfect location, close to most of the famous sightseeing locations, all within walking distance. A very tasty breakfast included with a huge selection, cereal and fruit, continental or cooked breakfast. Rooms and service were perfect."

Reviewed on 27 Jun 2026

Hotel Balestri
B&B Hotel Firenze City Center

B&B Hotel Firenze City Center

3 out of 5
Viale Giovanni Amendola 34 Florence FI
The price is £81 per night from 1 Jul to 2 Jul
£81
1 Jul - 2 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (768 reviews)
"It’s more like an old broken cheap motel. Room is clean enough but when you get out of the shower the shower towel is soaking wet because of water leaking from the shower towel the bathroom floor, the floor feels dirty and bathroom is wet, I wouldn’t dare to walk barefoot. $230 per night for that ..."

Reviewed on 15 Jun 2026

B&B Hotel Firenze City Center
Hotel Jane

Hotel Jane

3 out of 5
Via Orcagna 56-58 Florence FI
The price is £87 per night from 21 Jul to 22 Jul
£87
21 Jul - 22 Jul
includes taxes & fees
Stay at this hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.4/10 Very good! (536 reviews)
"ENJOYED OUR TIME. Thank you"

Reviewed on 25 Jun 2026

Hotel Jane
See all 888 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Croce

Find the best Santa Croce areas for the activities you enjoy most. Learn more about Santa Croce
Learn more about Santa Croce
A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

A historic bridge over a calm river at twilight, reflecting the surrounding buildings.

Oltrarno

Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.

Santa Croce Travel Guide

Choose two or more items and save on your trip:

Explore a world of travel with Expedia