
Santa Croce Holidays from £455
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Your Santa Croce Holiday
Experience all the fabulous things this neighbourhood has to offer with a tailor-made Santa Croce holiday package. However you picture yourself spending your time here, you'll find countless opportunities for adventure, relaxation and fun. Some popular nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Don't just think about it — do it! Book your ideal Santa Croce holiday with Expedia and experience travel your way.


Residenza Florentia
Reviewed on 12 Jun 2025

Grand Universe Lucca, Autograph Collection
Reviewed on 14 Aug 2025

Aurum Uffizi
Reviewed on 15 Jan 2026

Hotel Miceli - Civico 50
Reviewed on 29 Dec 2025
Where to stay in Santa Croce

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Top hotels in Santa Croce

Plaza Hotel Lucchesi
Excellent location. Staff was accommodative of our needs.
Reviewed on 30 Dec 2025

Aurum Uffizi
This is not a typical hotel where there is a lobby or staff to greet you . Instead it is a set of apartments in a corner building . The person who let us in was awaiting for us at the door at check in. Breakfast was serve in a buffet style . Staff would ask if you would order something else if you ...
Reviewed on 15 Jan 2026

FH55 Grand Hotel Mediterraneo
Nice hotel and great location
Reviewed on 24 Jan 2026
Frequently asked questions
Popular places to visit

Basilica of Santa Croce
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.
National Central Library of Florence
Learn about the local history of Florence when you spend time at National Central Library of Florence. Discover the area's beautiful sunsets and churches.
Things to do

Florence Accademia Gallery Tour with Entrance Ticket Included

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.













