
Santa Croce Holidays from £344
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Your Santa Croce Holiday
Experience all the fabulous things this neighbourhood has to offer with a tailor-made Santa Croce holiday package. However you picture yourself spending your time here, you'll find countless opportunities for adventure, relaxation and fun. Some popular nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Don't just think about it — do it! Book your ideal Santa Croce holiday with Expedia and experience travel your way.

The Moon Boutique Hotel & Spa
Reviewed on 13 Aug 2025

Aurum Uffizi
Reviewed on 19 Aug 2025

Aurum Firenze
Reviewed on 14 Aug 2025

Tenuta di Artimino Member of Meliá Collection
Reviewed on 21 Aug 2025
Where to stay in Santa Croce

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Top hotels in Santa Croce

Plaza Hotel Lucchesi
Reviewed on 18 Aug 2025

FH55 Grand Hotel Mediterraneo
Reviewed on 17 Aug 2025

Hotel Balestri
Reviewed on 21 Aug 2025
Frequently asked questions
Popular places to visit

Basilica of Santa Croce
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.

National Central Library of Florence
Learn about the local history of Florence when you spend time at National Central Library of Florence. Discover the area's beautiful sunsets and stunning cathedral.
Things to do

Florence: Pasta Cooking Class with Unlimited Wine

Visit Florence in golf car with Fiorentine tuorist guide
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.