Title: Santo Spirito Travel Guide: Best of Santo Spirito, Florence Travel 2025 | Expedia.co.uk [Hotels in Santo Spirito](https://expedia.co.uk/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.co.uk/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.co.uk/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santo-Spirito.d553248633938935375.Car-Hire-Guide)[Santo Spirito Holidays](https://expedia.co.uk/Santo-Spirito.d553248633938935375.Holidays-City-Breaks) # Santo Spirito Travel Guide ## Florence ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409791-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409789-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409407-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Spirito Things to do Hotels Where to stay [Florence travel guide](https://expedia.co.uk/Florence.dx1222) * * * ### Popular places to visit ![Piazza Santo Spirito](https://mediaim.expedia.com/destination/9/44b21491ec820fe5ef00b557ca71ac5d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santo Spirito 5/5(1 review) Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area. [](https://expedia.co.uk/Piazza-Santo-Spirito-Florence.d6265853.Attraction) ![Porta Romana](https://mediaim.expedia.com/destination/9/a02bf64b639fa2ffea10344e9452a522.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Porta Romana Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.co.uk/Porta-Romana-Florence.d501037.Attraction) ![Brancacci Chapel](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brancacci Chapel A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine. [](https://expedia.co.uk/Brancacci-Chapel-Historic-Centre-of-Florence.d6143202.Attraction) #### Santo Spirito Basilica Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.co.uk/Santo-Spirito-Basilica-Florence.d6075452.Attraction) #### Santa Maria della Carmine You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area. [](https://expedia.co.uk/Santa-Maria-Della-Carmine-Florence.d6075450.Attraction) #### Piazza del Carmine You can learn about the history of Florence with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art galleries. [](https://expedia.co.uk/Piazza-Del-Carmine-Oltrarno.d6265851.Attraction) ### Things to do ![Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour](https://mediaim.expedia.com/localexpert/507532/cbdef260-9919-420e-a482-1d2f9b3d6ccc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour £18 per adult **76%** of travellers recommend [](https://expedia.co.uk/things-to-do/skip-the-line-florence-duomo-priority-access-express-guided-tour.a507532.activity-details) ![Florence half day combo tour with David, Uffizi & Duomo](https://mediaim.expedia.com/localexpert/177530/67736287-bdb2-4b4e-a2f9-65e0ac592e0e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia £36 per adult **90%** of travellers recommend [](https://expedia.co.uk/things-to-do/florence-half-day-tour-with-uffizi.a177530.activity-details) ![Florence: Reserved Entry Ticket to Bargello Museum](https://mediaim.expedia.com/localexpert/4847727/c59bc38f-7641-4288-b707-dfc13ddc9284.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence: Reserved Entry Ticket to Bargello Museum £14 per adult [](https://expedia.co.uk/things-to-do/florence-reserved-entry-ticket-to-bargello-museum.a4847727.activity-details) ![Michaelangelo's David](https://mediaim.expedia.com/localexpert/519701/f78b6d6b-180c-4d4e-9a65-4adffb29c139.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Accademia timed-entry Ticket with Instant Delivery & Priority Access £25 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/accademia-timed-entry-ticket-with-instant-delivery-priority-access.a519701.activity-details) ![Florence: Unlimited Italy Internet with eSIM Mobile Data Plan](https://mediaim.expedia.com/localexpert/49429248/a081d0bf-3bb9-4fe5-b4c5-ee2a8c28652d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence: Unlimited Italy Internet with eSIM Mobile Data Plan £2 per traveller [](https://expedia.co.uk/things-to-do/florence-unlimited-italy-internet-with-esim-mobile-data-plan.a49429248.activity-details) ![Best of Florence Walking Tour](https://mediaim.expedia.com/localexpert/970108/bee6bf2e-9905-40b1-a7e6-463e79154a77.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of Florence Walking Tour £17 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/best-of-florence-walking-tour.a970108.activity-details) [See all activities in Florence](https://expedia.co.uk/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities) * * * ## Top hotels in Santo Spirito ![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Horto Convento Viale Ariosto, 13, Florence, FI £132 2 Nov - 3 Nov includes taxes & fees Stay at this 4-star hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. ... 9.6/10 Exceptional! (572 reviews) "This hotel is a tucked away gem. In fact, it’s difficult to find at first. The rooms were very clean and comfortable, and the property is beautiful.the included breakfast was delicious, and Olga makes wonderful coffees and cappuccinos. They serve cocktails and apertivo later in the day, and Adam ..." Reviewed on 6 Oct 2025 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true®ionId=553248633938935375) ![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palazzo Mannaioni Suites Via Maffia 9 - 17r, Florence, FI Stay at this 4-star residence in Florence. Enjoy free Wi-Fi, concierge services and satellite TV channels. Our guests praise the helpful staff in their reviews. ... 9.2/10 Wonderful! (1,036 reviews) "My stay was amazing! The property manager was so kind and let me check in early. The room was perfect with great views, spacious bathroom and good AC." Reviewed on 6 Oct 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F10%2F2025&endDate=24%2F10%2F2025&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.co.uk/Hotel-Search?startDate=23%2F10%2F2025&endDate=24%2F10%2F2025&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) ![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Vittoria Firenze Via Pisana 59, Florence, FI Fully refundableReserve now, pay when you stay £103 9 Nov - 10 Nov includes taxes & fees Stay at this 4-star boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. ... 8.4/10 Very Good! (987 reviews) "Amazing place, love the decor!" Reviewed on 28 Jul 2025 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F11%2F2025&endDate=10%2F11%2F2025&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) ![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Torre Del Cestello Via Borgo San Frediano, 8, Florence, FI Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ... 9/10 Wonderful! (212 reviews) "Lovely" Reviewed on 3 Oct 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F10%2F2025&endDate=24%2F10%2F2025&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.co.uk/Hotel-Search?startDate=23%2F10%2F2025&endDate=24%2F10%2F2025&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) ![Casa Santo Nome di Gesù](https://images.trvl-media.com/lodging/18000000/17910000/17907800/17907720/7a971b8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Santo Nome di Gesù Piazza del Carmine, 21, Florence, FI £121 2 Nov - 3 Nov includes taxes & fees Stay at this guesthouse in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ... 8.8/10 Excellent! (329 reviews) "Solo woman traveler here. Felt very safe. Loved the convenience and options of breakfast every morning. The garden is lovely and wished I had spent more time there. The room was nothing fancy, but my time there was great. Thankfully nobody was staying next door to my room because the last night I ..." Reviewed on 26 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) ![Hotel Firenze 2000](https://images.trvl-media.com/lodging/19000000/18670000/18665200/18665170/99e71450_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Firenze 2000 Viale Raffaello Sanzio, 16, Florence, FI £105 4 Nov - 5 Nov includes taxes & fees Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ... 7.2/10 Good! (180 reviews) "The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend." Reviewed on 4 Oct 2025 [](https://expedia.co.uk/Hotel-Search?startDate=04%2F11%2F2025&endDate=05%2F11%2F2025&selected=18665170&PinnedHotelID=18665170&HadPinnedHotel=true®ionId=553248633938935375) [See all 473 properties in Santo Spirito](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=10%2F10%2F2025&endDate=11%2F10%2F2025®ionId=553248633938935375) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Spirito hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-09&endDate=2025-10-10) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-09&endDate=2025-10-10) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-09&endDate=2025-10-10) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-09&endDate=2025-10-10)[9 Oct - 10 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-09&endDate=2025-10-10) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-10&endDate=2025-10-11) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-10&endDate=2025-10-11) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-10&endDate=2025-10-11) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-10&endDate=2025-10-11)[10 Oct - 11 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-10&endDate=2025-10-11) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025)[10 Oct - 12 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=10%2F10%2F2025&endDate=12%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025)[17 Oct - 19 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) * * * ### Other neighbourhoods around Santo Spirito ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Frediano San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town. [](https://expedia.co.uk/Florence-San-Frediano.dx6141947) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408952-Italy.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oltrarno 4.5/5(165 area reviews) Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood. [](https://expedia.co.uk/Florence-Oltrarno.dx6084345) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410264-Santa-Maria-Novella.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Santa Maria Novella 4/5(254 area reviews) Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. [](https://expedia.co.uk/Florence-Santa-Maria-Novella.dx6084343) ![Uffizi Gallery which includes street scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31661-Uffizi-Gallery-Galleria-Degli-Uffizi.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Giovanni If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing. [](https://expedia.co.uk/Florence-San-Giovanni.dx553248635976383065) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410270-Duomo-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Duomo 4.5/5(418 area reviews) Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood. [](https://expedia.co.uk/Florence-Duomo.dx6084346) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408985-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Centre of Florence Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. [](https://expedia.co.uk/Florence-Historic-Centre-Of-Florence.dx6141938) * * * * * * - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santo Spirito Travel Guide ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Oltrarno](https://www.expedia.co.uk/4Star-Oltrarno-Florence-Hotels.s40-n6084345-0.Travel-Guide-Filter-Hotels) - [Hotels near Basilica of Santa Maria Novella](https://www.expedia.co.uk/Basilica-Of-Santa-Maria-Novella-Hotels.0-l501050-0.Travel-Guide-Filter-Hotels) - [Hotels near Boboli Gardens](https://www.expedia.co.uk/Boboli-Gardens-Hotels.0-l507684-0.Travel-Guide-Filter-Hotels) - [Hotels near Brancacci Chapel](https://www.expedia.co.uk/Brancacci-Chapel-Hotels.0-l6143202-0.Travel-Guide-Filter-Hotels) - [Hotels near Chiesa di Ognissanti](https://www.expedia.co.uk/Chiesa-Di-Ognissanti-Hotels.0-l6075398-0.Travel-Guide-Filter-Hotels) - 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