Title: Santo Spirito Travel Guide: Best of Santo Spirito, Florence Travel 2026 | Expedia.co.uk [Hotels in Santo Spirito](https://expedia.co.uk/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.co.uk/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.co.uk/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santo-Spirito.d553248633938935375.Car-Hire-Guide)[Santo Spirito Holidays](https://expedia.co.uk/Santo-Spirito.d553248633938935375.Holidays-City-Breaks) # Santo Spirito Travel Guide ## Florence ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409791-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409789-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409407-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Spirito Things to do Hotels Where to stay [Florence travel guide](https://expedia.co.uk/Florence.dx1222) --- ### Popular places to visit ![Piazza Santo Spirito](https://mediaim.expedia.com/destination/9/44b21491ec820fe5ef00b557ca71ac5d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santo Spirito 5/5(1 review) Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area. [](https://expedia.co.uk/Piazza-Santo-Spirito-Florence.d6265853.Attraction) ![Porta Romana](https://mediaim.expedia.com/destination/9/a02bf64b639fa2ffea10344e9452a522.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Porta Romana Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.co.uk/Porta-Romana-Florence.d501037.Attraction) ![Brancacci Chapel](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brancacci Chapel A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine. [](https://expedia.co.uk/Brancacci-Chapel-Historic-Centre-of-Florence.d6143202.Attraction) #### Santo Spirito Basilica Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.co.uk/Santo-Spirito-Basilica-Florence.d6075452.Attraction) #### Torrigiani Garden Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area. [](https://expedia.co.uk/Torrigiani-Garden-Florence.d553248621532498389.Attraction) #### Santa Maria della Carmine You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the notable monuments and stunning cathedral in this vibrant area. [](https://expedia.co.uk/Santa-Maria-Della-Carmine-Florence.d6075450.Attraction) ### Things to do ![Florence Accademia Gallery Tour with Entrance Ticket Included](https://mediaim.expedia.com/localexpert/3066485/d26c5e31-1f44-4056-bdee-2fc35c6c6ffc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Accademia Gallery Tour with Entrance Ticket Included £33 per adult **92%** of travellers recommend [](https://expedia.co.uk/things-to-do/florence-accademia-gallery-tour-with-entrance-ticket-included.a3066485.activity-details) ![Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour](https://mediaim.expedia.com/localexpert/507532/cbdef260-9919-420e-a482-1d2f9b3d6ccc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour £17 per adult **80%** of travellers recommend [](https://expedia.co.uk/things-to-do/skip-the-line-florence-duomo-priority-access-express-guided-tour.a507532.activity-details) ![Micheal Angelo's David](https://mediaim.expedia.com/localexpert/2479829/2bebb71d-abeb-452a-9a00-2b6fddf3b233.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket £27 per adult **86%** of travellers recommend [](https://expedia.co.uk/things-to-do/skip-the-line-florences-accademia-gallery-priority-entrance-ticket.a2479829.activity-details) ![Florence: Timed Entrance Ticket to Michelangelo’s David](https://mediaim.expedia.com/localexpert/4843397/e6e8918a-a66d-4caf-a8de-ac69d4a02380.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence: Timed Entry to Michelangelo's David + Audio App £21 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/florence-timed-entry-to-michelangelos-david-audio-app.a4843397.activity-details) ![Florence half day combo tour with David, Uffizi & Duomo](https://mediaim.expedia.com/localexpert/177530/67736287-bdb2-4b4e-a2f9-65e0ac592e0e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia £24 per adult **92%** of travellers recommend [](https://expedia.co.uk/things-to-do/florence-half-day-tour-with-uffizi.a177530.activity-details) ![Pisa and Piazza dei Miracoli Half Day Tour from Florence](https://mediaim.expedia.com/localexpert/558114/ee5005a3-7dc7-4d52-b37b-cb457ae399b1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pisa and Piazza dei Miracoli Half Day Tour from Florence £27 per adult **88%** of travellers recommend [](https://expedia.co.uk/things-to-do/pisa-and-piazza-dei-miracoli-half-day-tour-from-florence.a558114.activity-details) [See all activities in Florence](https://expedia.co.uk/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities) --- ## Top hotels in Santo Spirito ![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Horto Convento Viale Ariosto, 13 Florence FI £90 29 Jan - 30 Jan includes taxes & fees Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ... 9.6/10 Exceptional! (605 reviews) Beautiful building and rooms, interesting Reviewed on 6 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F01%2F2026&endDate=30%2F01%2F2026&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true®ionId=553248633938935375) ![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palazzo Mannaioni Suites Via Maffia 9 - 17r Florence FI Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and satellite TV channels. Our guests praise the helpful staff in their reviews. Popular ... 9.2/10 Wonderful! (1,063 reviews) Staff, location, and the apartment were all 10/10! Novella welcomed us at the property. She was incredibly friendly, very informative, and gave us great recommendations for things to do and places to eat. The flat was spotless and very well set up. Additional towels were provided, and we really appreciated ... Reviewed on 6 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) ![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Vittoria Firenze Via Pisana 59 Florence FI £91 1 Feb - 2 Feb includes taxes & fees Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ... 8.4/10 Very Good! (988 reviews) Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back! Reviewed on 1 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F02%2F2026&endDate=02%2F02%2F2026&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) ![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Torre Del Cestello Via Borgo San Frediano, 8 Florence FI £73 12 Jan - 13 Jan includes taxes & fees Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ... 9/10 Wonderful! (230 reviews) Beautiful place to stay. Just outside of the bustle but walking within distance. Warmly welcomed and staff were lovely. Reviewed on 25 Dec 2025 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F01%2F2026&endDate=13%2F01%2F2026&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) ![Oltrarno Splendid](https://images.trvl-media.com/lodging/36000000/35630000/35625200/35625179/23b1bfc3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Oltrarno Splendid Via dei Serragli 7 Florence FI £131 19 Jan - 20 Jan includes taxes & fees Stay at this B&B in Florence. Enjoy free breakfast, free Wi-Fi and daily housekeeping. Our guests praise the helpful staff in their reviews. Popular attractions ... 9.8/10 Exceptional! (101 reviews) Rooms are very comfy and super quiet... Great bedding. Love the eclectic decor, as well. Staff is extremely friendly and helpful. I highly recommend this hotel. Reviewed on 5 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F01%2F2026&endDate=20%2F01%2F2026&selected=35625179&PinnedHotelID=35625179&HadPinnedHotel=true®ionId=553248633938935375) ![Casa Santo Nome di Gesù](https://images.trvl-media.com/lodging/18000000/17910000/17907800/17907720/7a971b8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Santo Nome di Gesù Piazza del Carmine, 21 Florence FI Stay at this guesthouse in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ... 8.8/10 Excellent! (342 reviews) Really a nice place, like the room style and good for family stay! Reviewed on 1 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) [See all 492 properties in Santo Spirito](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=10%2F01%2F2026&endDate=11%2F01%2F2026®ionId=553248633938935375) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Spirito hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-09&endDate=2026-01-10)[9 Jan - 10 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-09&endDate=2026-01-10) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-10&endDate=2026-01-11)[10 Jan - 11 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2026-01-10&endDate=2026-01-11) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=09%2F01%2F2026&endDate=11%2F01%2F2026)[9 Jan - 11 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=09%2F01%2F2026&endDate=11%2F01%2F2026) --- ### Other neighbourhoods around Santo Spirito ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Frediano San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town. [](https://expedia.co.uk/Florence-San-Frediano.dx6141947) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408952-Italy.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oltrarno 4.5/5(165 area reviews) Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood. [](https://expedia.co.uk/Florence-Oltrarno.dx6084345) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410264-Santa-Maria-Novella.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Santa Maria Novella 4/5(254 area reviews) Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. [](https://expedia.co.uk/Florence-Santa-Maria-Novella.dx6084343) ![Uffizi Gallery which includes street scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31661-Uffizi-Gallery-Galleria-Degli-Uffizi.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Giovanni If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing. [](https://expedia.co.uk/Florence-San-Giovanni.dx553248635976383065) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408985-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Centre of Florence Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. [](https://expedia.co.uk/Florence-Historic-Centre-Of-Florence.dx6141938) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410270-Duomo-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Duomo 4.5/5(418 area reviews) Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood. [](https://expedia.co.uk/Florence-Duomo.dx6084346) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santo Spirito Travel Guide ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Oltrarno ](https://www.expedia.co.uk/4Star-Oltrarno-Florence-Hotels.s40-n6084345-0.Travel-Guide-Filter-Hotels) - [Hotels near Basilica of Santa Maria Novella ](https://www.expedia.co.uk/Basilica-Of-Santa-Maria-Novella-Hotels.0-l501050-0.Travel-Guide-Filter-Hotels) - [Hotels near Boboli Gardens ](https://www.expedia.co.uk/Boboli-Gardens-Hotels.0-l507684-0.Travel-Guide-Filter-Hotels) - [Hotels near Brancacci Chapel ](https://www.expedia.co.uk/Brancacci-Chapel-Hotels.0-l6143202-0.Travel-Guide-Filter-Hotels) - [Hotels near Chiesa di Ognissanti ](https://www.expedia.co.uk/Chiesa-Di-Ognissanti-Hotels.0-l6075398-0.Travel-Guide-Filter-Hotels) - 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