Santo Spirito Travel Guide

Name: Palazzo Mannaioni Suites
Price range: £127
Rating: 9.2

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.

A stone bridge over a calm river, with historic buildings on either side.

A bustling outdoor market with white tents and various stalls.

A church with a bell tower, a circular window, and a weather vane.

A cityscape with a river, a bridge, and mountains in the background.

Visit Santo Spirito

Things to do

Hotels

Florence travel guide

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and notable monuments in this vibrant area.

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Things to do

Florence: Pasta Cooking Class with Unlimited Wine

£14

per adult

94% of travellers recommend

City Sightseeing Florence Hop-on Hop-off Bus Tour

£21

per adult

76% of travellers recommend

Best of Florence Tour with Fast Track Accademia & Duomo

Best of Florence Tour with David at Accademia & Duomo (with VIP option)

£57

per adult

96% of travellers recommend

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

£30

per adult

86% of travellers recommend

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

£15

per adult

80% of travellers recommend

Accademia timed-entry Ticket with Instant Delivery & Priority Access

£35

per adult

94% of travellers recommend

See all activities in Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Viale Ariosto, 13 Florence FI

£133

31 Aug - 1 Sept

includes taxes & fees

Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. Popular ...

9.8/10 Exceptional! (713 reviews)

"Good location, close to main attractions."

Reviewed on 21 Aug 2026

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI

£77

27 Aug - 28 Aug

includes taxes & fees

Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Piazza del Duomo ...

9.2/10 Wonderful! (300 reviews)

"We had a wonderful 3 night stay here. The room was spacious with beautiful views overlooking the Arno river. The air conditioning worked very well in the room and was much appreciated during a heat wave in August. The location could not be beat. It is away from the major crowds, but still surrounded ..."

Reviewed on 25 Aug 2026

UNA Hotels Vittoria Firenze

Via Pisana 59 Florence FI

£74

30 Aug - 31 Aug

includes taxes & fees

Stay at this boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular ...

8.4/10 Very good! (1,006 reviews)

"Very clean, nice rooms, staff and great breakfast / evening food in the restaurant. Location 20min walk to main Santa Maria Station."

Reviewed on 16 Aug 2026

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI

£77

31 Aug - 1 Sept

includes taxes & fees

Stay at this guesthouse in Florence. Enjoy free Wi-Fi, 2 meeting rooms and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...

8.8/10 Excellent! (235 reviews)

"There was a fridge and AC in the room which was nice. Check-in desk was friendly, we actually checked in like an hour early and when checking out we checked out 15 minutes late, not charged and were able to drop our bags with a bathroom available in the lobby. The area felt safe at night and there ..."

Reviewed on 14 Aug 2026

Palazzo Mannaioni Suites

Via Maffia 9 - 17r Florence FI

£127

27 Aug - 28 Aug

includes taxes & fees

Stay at this residence in Florence. Enjoy free Wi-Fi, concierge services and premium bedding. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.2/10 Wonderful! (1,161 reviews)

"Great stay, wonderful hosts!"

Reviewed on 25 Aug 2026

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI

Stay at this hostel in Florence. Enjoy free Wi-Fi, daily housekeeping and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza del ...

7.8/10 Good! (64 reviews)

"No"

Reviewed on 30 Jul 2026

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See all 500 properties in Santo Spirito

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas for the activities you enjoy most. Learn more about Santo Spirito

A river with buildings on the right bank.

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

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A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

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