Santo Spirito Holidays from £273

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Your Santo Spirito Holiday

Experience the best that Santo Spirito has to offer with a tailor-made Santo Spirito holiday package. From its walking and views to its culture, you'll quickly fall for the charms of this residential neighbourhood. Not sure what to do during your trip to Santo Spirito? Nearby attractions like Piazza Santo Spirito, Santo Spirito Basilica and Brancacci Chapel are good places to begin. Expedia is here to put your travel plans into action. Book your perfect Santo Spirito holiday today.

Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £558, price is now £273 per person
£273
per person
18 Aug - 21 Aug
found 20 hours ago
Return flight included
London (LGW) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
Limpio, silencioso, excelente ubicación

Reviewed on 11 Jul 2026

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £854, price is now £415 per person
£415
per person
28 Sept - 2 Oct
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
7.4/10 Good! (1,008 reviews)
Good service and the room was clean

Reviewed on 10 Jul 2026

Park Hotel Villa Ariston

Park Hotel Villa Ariston

4 out of 5
Price was £913, price is now £478 per person
£478
per person
25 Sept - 1 Oct
found 19 hours ago
Return flight included
London (LHR) to Florence (FLR)
8.8/10 Excellent! (133 reviews)
Recommend - traditional family run hotel

Reviewed on 8 Jul 2026

EXE Toscana

EXE Toscana

4 out of 5
Lucca Historical Center
Save 100% on your flight
Price was £719, price is now £398 per person
£398
per person
25 Sept - 1 Oct
found 19 hours ago
Return flight included
London (LHR) to Florence (FLR)
8.4/10 Very good! (837 reviews)
The description says “In the heart of Lucca's historic center.” It is not but about a 15-20 minute walk from the start of the walled city. Not too far from the train. Location is ok but nothing charming about it. The front desk staff were very pleasant. The room could have had stronger air con but it was ok despite the 92 degree weather. The Wi-fi was incredibly slow. The room and bathroom are very small. Could have used more towels. The bed is very hard so not too comfortable. The hotel was ok but nothing special.

Reviewed on 5 Jul 2026

Villa Cora

Villa Cora

5 out of 5
Oltrarno
Save 100% on your flight
Price was £1,956, price is now £1,110 per person
£1,110
per person
16 Sept - 19 Sept
found 10 hours ago
Return flight included
London (LON) to Florence (FLR)
9.8/10 Exceptional! (476 reviews)
Worst service and the place dose not worth the price you are paying , please do your research before booking it, if not you will regret

Reviewed on 23 Jun 2026

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
The price is £129 per night from 11 Aug to 12 Aug
£129
11 Aug - 12 Aug
includes taxes & fees
9.8/10 Exceptional! (686 reviews)
"Beautiful, clean, amazing breakfast, really nice staff. 10/10 recommendation"

Reviewed on 7 Jul 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Fully refundableReserve now, pay when you stay
The price is £113 per night from 11 Aug to 12 Aug
£113
11 Aug - 12 Aug
includes taxes & fees
9/10 Wonderful! (276 reviews)
"Clean room with good location and air conditioner Shops and restaurants nearby"

Reviewed on 10 Jul 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
Fully refundableReserve now, pay when you stay
The price is £76 per night from 2 Aug to 3 Aug
£76
2 Aug - 3 Aug
includes taxes & fees
8.4/10 Very good! (1,001 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on 12 May 2026

UNA Hotels Vittoria Firenze
See all 520 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santo Spirito travel package cost?
We make it simple for everyone to travel, with Santo Spirito travel packages starting from as little as £273. You'll have the flexibility to bundle your preferred hotels, airlines and car rental. For the ultimate escape, why not add a few tours and experiences to your itinerary?
If I'm not able to travel, can I cancel my Santo Spirito travel package?
Don't worry if you're rethinking your Santo Spirito travel package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We get that life can occasionally throw a spanner in the travel works, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we're here to help.
How do I get a cheap travel package to Santo Spirito?
One of the easiest ways to save money (and time) is to combine your bookings with Expedia. Hotels, flights, activities and rental cars — we've got them all covered. Pick and choose a combination that suits you and watch your savings stack up. We know a package deal is never one-size-fits-all. That's why we offer over 550 air carriers and 1,000,000 hotel options across the world, which lets you customize your Santo Spirito holiday.
Does Expedia offer Book Now, Pay Later Santo Spirito holidays?
Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply pick the payment plan that suits you best during the checkout process and take the stress out of budgeting for your next trip. Don't forget to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your buck. Consider these flexible payment options below:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's convenient monthly instalment plans. If paying bite-sized amounts each month sounds right for you, pick this option during the checkout process.
  • Pay in instalments holidays: Like the idea of paying off your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan from Klarna.

What are the top hotels in Santo Spirito?
Get your holiday off to a good start by locking in a room at B&B Monte Oliveto. It's one of most popular hotels in Santo Spirito. Another comfortable option is Ottantotto Firenze.
How far in advance should I book my Santo Spirito holiday?
While not all air carriers release ticket prices early, you can normally compare international fares on Expedia up to a year in advance. This is the time you can score some fantastic deals. If you've left things to the last minute, you might still be in luck. Low prices occasionally become available only weeks prior to departure.
What does an Expedia Santo Spirito travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your ideal Santo Spirito package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget — the more you bundle, the bigger the savings!
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your escape together is one of the easiest ways to save. Bundle car rentals, airfares and hotels into a handy package. But your options don't end at hotels. Expedia features all sorts of properties, including holiday rentals like beachside villas and spacious residences. Your choices are almost endless!
Can I choose my airline with a Santo Spirito Expedia travel package?
Expedia offers access to more than 550 airline partners worldwide, so you definitely can. Simply select the carrier you want and create the perfect Santo Spirito holiday.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
See properties

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£25
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Small-Group Wine Tasting Experience in the Tuscan Countryside

Small-Group Wine Tasting Experience in the Tuscan Countryside

£77
per adult
98% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

£35
per adult
94% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.