Santo Spirito Holidays from £258

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Your Santo Spirito Holiday

Experience the best that Santo Spirito has to offer with a tailor-made Santo Spirito holiday package. From its walking and views to its culture, you'll quickly fall for the charms of this residential neighbourhood. Not sure what to do during your trip to Santo Spirito? Nearby attractions like Piazza Santo Spirito, Santo Spirito Basilica and Brancacci Chapel are good places to begin. Expedia is here to put your travel plans into action. Book your perfect Santo Spirito holiday today.

Price found within the past 48 hours. Click for updated prices.
Rocca Palazzaccio

Rocca Palazzaccio

3 out of 5
Save 100% on your flight
per person
18 Aug - 21 Aug
found 21 hours ago
Return flight included
London (LON) to Florence (FLR)
9/10 Wonderful! (13 reviews)
The apartment is great as is the pool, and marco who looks after it is very nice. There is absolutely nothing in the area, you need to get the 37 bus to Florence if you want to eat or drink anything. The co-op is closed from 8pm and all day Sunday, the only restaurant closed down recently so at 7:30pm on a Saturday we found ourselves with nowhere whatsoever to eat. We had bread that we bought earlier at the shop, and on Sunday we ate in Florence before getting the bus back - be careful, half of the buses don’t turn up Recommended for sure if you have a car, the complex is excellent, but the local village is desolate

Reviewed on 24 Aug 2023

Hotel Bencista

Hotel Bencista

3 out of 5
per person
14 Aug - 18 Aug
found 10 hours ago
Return flight included
London (LGW) to Florence (FLR)
7.2/10 Good! (11 reviews)
Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
2 Sept - 6 Sept
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
7.8/10 Good! (1,000 reviews)
If one is not there for a fancy hotel room, but for sightseeing, this is a great, clean, bare bones room. It is close to the train station. We were on the 5th floor and had a great view! Breakfast was also on the 5th floor. Close proximity to all the museums and Duomo, 20 minute walk or less to everything. We walked everywhere!

Reviewed on 21 Jun 2025

Cappuccina Country Resort

Cappuccina Country Resort

4 out of 5
Save 100% on your flight
per person
15 Aug - 22 Aug
found 22 hours ago
Return flight included
London (LON) to Florence (FLR)
8.4/10 Very Good! (69 reviews)
We absolutely loved our stay. I wish we got to stay longer. The hotel and the town are so lovely and peaceful. I could have easily stayed there for three days. The staff was so kind. The room was comfortable and very luxurious. Breakfast was yummy.

Reviewed on 28 May 2025

Grand Hotel Cavour

Grand Hotel Cavour

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
2 Sept - 6 Sept
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
9.2/10 Wonderful! (1,003 reviews)
Fantastic people and best view in Florence at night. Breakfast the best in Florence. Would go back in a heart beat

Reviewed on 25 Jun 2025

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
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Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Santo Spirito

Palazzo Mannaioni Suites
Palazzo Mannaioni Suites
4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is £242 per night from 29 Jun to 30 Jun
£242
29 Jun - 30 Jun
includes taxes & fees
9.2/10 Wonderful! (991 reviews)
"Great location. Clean. Hospitable"

Reviewed on 24 Jun 2025

Palazzo Mannaioni Suites
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is £125 per night from 27 Jul to 28 Jul
£125
27 Jul - 28 Jul
includes taxes & fees
9.6/10 Exceptional! (529 reviews)
"We loved our stay @ The Convent. It was a pity there was no pool or restaurant"

Reviewed on 23 Jun 2025

Hotel Horto Convento
UNA HOTELS Vittoria Firenze
UNA HOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is £107 per night from 29 Jun to 30 Jun
£107
29 Jun - 30 Jun
includes taxes & fees
8.4/10 Very Good! (986 reviews)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice"

Reviewed on 31 May 2025

UNA HOTELS Vittoria Firenze
See all 463 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Holidays

All Inclusive Holidays

Beach Holidays

Beach Holidays

Family Friendly Holidays

Family Friendly Holidays

Frequently asked questions

How much does a Santo Spirito travel package cost?
We make it simple for everyone to travel, with Santo Spirito travel packages starting from as little as £258. You'll have the flexibility to bundle your preferred hotels, airlines and car rental. For the ultimate escape, why not add a few tours and experiences to your itinerary?
If I'm not able to travel, can I cancel my Santo Spirito travel package?
Don't worry if you're rethinking your Santo Spirito travel package --- it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We get that life can occasionally throw a spanner in the travel works, so make your way to our Customer Service Portal if that occurs. When you're ready to make changes, we're here to help.
How do I get a cheap travel package to Santo Spirito?
One of the easiest ways to save money (and time) is to combine your bookings with Expedia. Hotels, flights, activities and rental cars --- we've got them all covered. Pick and choose a combination that suits you and watch your savings stack up. We know a package deal is never one-size-fits-all. That's why we offer over 550 air carriers and 1,000,000 hotel options across the world, which lets you customize your Santo Spirito holiday.
Does Expedia offer Book Now, Pay Later Santo Spirito holidays?
Good news! We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply pick the payment plan that suits you best during the checkout process and take the stress out of budgeting for your next trip. Don't forget to bundle your accommodation, car hire and flights with Expedia to get the biggest bang for your buck. Consider these flexible payment options below:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's convenient monthly instalment plans. If paying bite-sized amounts each month sounds right for you, pick this option during the checkout process.
  • Pay in instalments holidays: Like the idea of paying off your holiday in multiple transactions? Then go for this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, opt for a low deposit holiday payment plan from Klarna.

What are the top hotels in Santo Spirito?
Get your holiday off to a good start by locking in a room at B&B Monte Oliveto. It's one of most popular hotels in Santo Spirito. Another comfortable option is Ottantotto Firenze.
How far in advance should I book my Santo Spirito holiday?
While not all air carriers release ticket prices early, you can normally compare international fares on Expedia up to a year in advance. This is the time you can score some fantastic deals. If you've left things to the last minute, you might still be in luck. Low prices occasionally become available only weeks prior to departure.
What does an Expedia Santo Spirito travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your ideal Santo Spirito package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Don't forget --- the more you bundle, the bigger the savings!
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your escape together is one of the easiest ways to save. Bundle car rentals, airfares and hotels into a handy package. But your options don't end at hotels. Expedia features all sorts of properties, including holiday rentals like beachside villas and spacious residences. Your choices are almost endless!
Can I choose my airline with a Santo Spirito Expedia travel package?
Expedia offers access to more than 550 airline partners worldwide, so you definitely can. Simply select the carrier you want and create the perfect Santo Spirito holiday.

Popular places to visit

Brancacci Chapel

Brancacci Chapel

A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.

Brancacci Chapel

Things to do

Florence: Pasta Making Class with Wine, Limoncello, and Cake

Florence: Pasta Class with Wine, Limoncello and Dessert

£59
per adult
100% of travellers recommend
Florence: Pasta Class with Wine, Limoncello and Dessert
Florence: Santa Monaca Church Italian Opera Concert Ticket

Florence: Santa Monaca Church Italian Opera Concert Ticket

£25
per adult
100% of travellers recommend
Florence: Santa Monaca Church Italian Opera Concert Ticket
Pastamania - Florence Pasta Making Class

Pastamania - Florence Pasta Making Class

£59
per adult
100% of travellers recommend
Pastamania - Florence Pasta Making Class
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.