The hotel is located in the middle of the city right across from the train station. Buses and trains to everywhere are nearby. Most places are within walking distance. The city tour bus passes in front of the hotel. It can be a little noisy at night due to a lot of new comers to Frankfurt that literally own the place now... To my opinion, I think Munich, Berlin, Düsseldorf could be better places to visit, unless you're curious to see what Frankfurt looks like. Otherwise, it was a pleasant stay. Hotel was good and due to the location you won't spend lots of money taking the cab which kind of expensive. Another thing, the trains S8 and S9 take you to terminal 1 inside the airport which cost about €5 per person from platform 103, main station underground. Instead of €35 for a taxi. All of that across the hotel.