Title: Santo Spirito Hospital in Rome City Centre | Expedia.co.uk [Santo Spirito Hospital Hotels](https://expedia.co.uk/Santo-Spirito-Hospital-Hotels.0-l6227560-0.Travel-Guide-Filter-Hotels)[Santo Spirito Hospital Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santo-Spirito-Hospital.d6227560.Car-Hire-Guide)[Rome City Centre Holidays](https://expedia.co.uk/Rome-City-Centre.d553248633938945217.Holidays-City-Breaks) # Santo Spirito Hospital ## Visit Santo Spirito Hospital Activities * * * * * * ## Plan a trip to see Santo Spirito Hospital Price found within the past 48 hours. Click for updated prices. ![Grand Hotel Olympic](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/a302c22a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Grand Hotel Olympic Rome City Centre £168 per person 29 Nov - 2 Dec found 2 days ago Return flight included Birmingham (BHX) to Rome (FCO) 7.4/10 Good! (1,020 reviews) The staff is great. Very friendly and kind. Reviewed on 27 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-11-29/2025-12-02/?FromAirport=BHX&Destination=FCO&NumRoom=1&NumAdult=2&NumChild=0&hotelId=72827&paandie=true&dealMarker=bYeZ0zNbyuTEHYoqBgyX51fC8VG2YzRRjd4pUw1TYnoB2JT6HvdaDG57NTQ5r_Da) ![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/aa8b51a2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais de la Poste Rome City Centre £289 per person 29 Nov - 2 Dec found 1 day ago Return flight included London (LGW) to Rome (FCO) 9.2/10 Wonderful! (574 reviews) Very nice and perfect location with reasonable prices, will stay again Reviewed on 20 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-11-29/2025-12-02/?FromAirport=LGW&Destination=FCO&NumRoom=1&NumAdult=2&NumChild=0&hotelId=38902220&paandie=true&dealMarker=bYeZ0zNbyuTEHYoqBgyX52f9Nh1rc5DJRz6k57nofLzR06ZtCmr5O5EAYxkiQg-C) ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/6b9ee00e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio Save 100% on your flight £373 per person 22 Dec - 26 Dec found 19 hours ago Return direct flight included Birmingham (BHX) to Rome (FCO) 9.6/10 Exceptional! (307 reviews) Clean room and friendly staff. Reviewed on 27 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-22/2025-12-26/?FromAirport=BHX&Destination=FCO&NumRoom=1&NumAdult=2&NumChild=0&hotelId=33120475&paandie=true&dealMarker=NfBY7VBgZBOObfSdRRYxwE_H3C4ZU2j2hZiTAZpBqCPCYQJCnsdoWPPbQrzdY6kH) ### Tours & day trips [See all 400 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=ToursDayTrips) ![Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill](https://mediaim.expedia.com/localexpert/166587/4edbea50-914d-4144-a851-55e98d3e0a1f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill 1h 30m+ 9.2/10 3,843 reviews Free cancellation available £30 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-ancient-rome-guided-tour-with-roman-forum-palatine-hill.a166587.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour](https://mediaim.expedia.com/localexpert/166597/4f9bb377-01c6-4b8f-980f-7747e7f07a85.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour 2h+ 9/10 6,481 reviews Free cancellation available £78 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vatican-museums-sistine-chapel-st-peters-basilica-fully-guided-tour.a166597.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basil...](https://mediaim.expedia.com/localexpert/1008396/d1b7fce5-e5c4-48ff-9148-df750d6ee6ce.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basil... 3h 8.8/10 323 reviews Free cancellation available £144 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-group-tour-of-the-vatican-sistine-chapel-st-peters-basilica.a1008396.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour](https://mediaim.expedia.com/localexpert/3138351/99f75742-d99d-48ce-8246-922f96cce825.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour 2h 30m 8.4/10 234 reviews Free cancellation available £26 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-colosseum-with-arena-roman-forum-and-palatine-guided-tour.a3138351.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Pompeii, Amalfi Coast and Positano Day Trip from Rome](https://mediaim.expedia.com/localexpert/442250/aa41f01e-adac-4892-9511-7475ae5b39d6.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pompeii, Amalfi Coast and Positano Day Trip from Rome 13h 9.2/10 428 reviews Free cancellation available £86 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-positano-day-trip-from-rome.a442250.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Hop-On Hop-Off Big Bus Tour by Open-Top Bus](https://mediaim.expedia.com/localexpert/376190/27f7cb2b-8299-411e-bfc9-45c2f55e37d8.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Hop-On Hop-Off Big Bus Tour by Open-Top Bus 1d+ 8.2/10 2,025 reviews Free cancellation available £25 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-hop-on-hop-off-big-bus-tour-by-open-top-bus.a376190.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option](https://mediaim.expedia.com/localexpert/238327/66f41112-0db2-4e77-9ec7-cb838b38abe8.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option 12h 8.8/10 100 reviews Free cancellation available £77 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-sorrento-day-trip-from-rome.a238327.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting](https://mediaim.expedia.com/localexpert/166552/04a98a7b-1b9b-4323-933f-1da13e16b5ee.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting 11h 9.6/10 945 reviews Free cancellation available £91 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/from-rome-tuscany-montepulciano-day-trip-including-lunch-wine-tasting.a166552.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Hop-On Hop-Off Rome Panoramic Bus Tour](https://mediaim.expedia.com/localexpert/247607/46ec5568-4f35-4dd7-87bf-af6d6d137569.jpg?impolicy=resizecrop&rw=500&rh=280) ### Hop-On Hop-Off Rome Panoramic Bus Tour 2h+ 7.6/10 557 reviews Free cancellation available £17 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/hop-on-hop-off-rome-panoramic-bus-tour.a247607.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Crypts and Roman Catacombs Small-Group Guided Tour with Coach Transfers](https://mediaim.expedia.com/localexpert/166554/24f66cc8-3984-40f2-8464-7f511b37cd70.jpg?impolicy=resizecrop&rw=500&rh=280) ### Crypts and Roman Catacombs Small-Group Guided Tour with Coach Transfers 3h 30m 9.2/10 832 reviews Free cancellation available £48 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/crypts-and-roman-catacombs-small-group-guided-tour-with-coach-transfers.a166554.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Food, drink & nightlife [See all 72 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=FoodDrinkNightlife) ![The Roman Food Tour in Trastevere with Free-Flowing Fine Wine](https://mediaim.expedia.com/localexpert/1012380/d1979d93-c575-4eff-ae81-e0d1cc7f51ec.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Roman Food Tour in Trastevere with Free-Flowing Fine Wine 4h 9.8/10 41 reviews Free cancellation available £109 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-roman-food-tour-in-trastevere-with-free-flowing-fine-wine.a1012380.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour](https://mediaim.expedia.com/localexpert/166608/8447e5f4-3c26-475b-beb8-84f570ef6336.jpg?impolicy=resizecrop&rw=500&rh=280) ### VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour 3h 9/10 103 reviews £156 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vip-vatican-breakfast-sistine-chapel-and-st-peters-basilica-guided-tour.a166608.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Street Food Tour with Local Guide](https://mediaim.expedia.com/localexpert/2124035/14fd9e77-2f7a-4a8e-86bb-f26685ffa41a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Street Food Tour with Local Guide 2h 30m 9.8/10 8 reviews Free cancellation available £39 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-street-food-tour-with-local-guide.a2124035.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu](https://mediaim.expedia.com/localexpert/2128072/99424690-45a6-41c0-80b9-d6dd8583fa44.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu 3h 9.6/10 59 reviews Free cancellation available £69 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/3-in-1-cooking-class-piazza-navona-fettuccine-ravioli-and-tiramisu.a2128072.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Learn to Make Pasta & Tiramisu with Wine and Limoncello Included](https://mediaim.expedia.com/localexpert/3087530/f87dc754-fe4a-40ab-968b-33ecea2028d9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Learn to Make Pasta & Tiramisu with Wine and Limoncello Included 2h 9.8/10 21 reviews Free cancellation available £61 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-cooking-class-fettuccine-tiramisu-lovers-workshop.a3087530.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine](https://mediaim.expedia.com/localexpert/1088407/cc51bcb9-036a-433d-adde-e731983a97fc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine 3h 9/10 20 reviews Free cancellation available £69 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/hidden-rome-food-tour-in-trastevere-with-dinner-and-wine.a1088407.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Pasta Making Class with Wine, Limoncello, and Dessert](https://mediaim.expedia.com/localexpert/48186377/f98f744d-aab2-413c-b23f-edf172a12f11.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Pasta Making Class with Wine, Limoncello, and Dessert 3h 9.8/10 11 reviews Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-pasta-making-class-with-wine-limoncello-and-cake.a48186377.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo](https://mediaim.expedia.com/localexpert/1012378/acd7e3f4-e1d1-4ca6-8f4f-73dbd81ae671.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo 4h 9.8/10 37 reviews Free cancellation available £86 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-food-wine-tour-in-prati.a1012378.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert](https://mediaim.expedia.com/localexpert/1182002/1cc696ba-8268-44cf-909e-72bbe3ccf7dd.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert 3h 30m Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pizza-and-pasta-master-class-with-wine-and-tiramisu-on-the-ancient-appian-way.a1182002.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Become a Masterchef in Rome: Pasta, Ravioli and Tiramisù Class](https://mediaim.expedia.com/localexpert/1049360/24db1622-0942-4617-b8a9-57b46010d9e0.jpg?impolicy=resizecrop&rw=500&rh=280) ### Become a Masterchef in Rome: Pasta, Ravioli and Tiramisù Class 3h 10/10 4 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/become-a-roman-masterchef-pasta-ravioli-and-tiramisu-class.a1049360.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Private & custom tours [See all 69 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=Privatecustomtours) ![Private Guided Tour of Vatican, Sistine Chapel & St Peter’s Basilica](https://mediaim.expedia.com/localexpert/443106/c1c43679-f20f-4a91-9736-bb836a739ef6.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private Guided Tour of Vatican, Sistine Chapel & St Peter’s Basilica 2h 30m 8.6/10 27 reviews Free cancellation available £87 includes taxes & fees per traveller\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/private-tour-no-wait-entry-vatican-sistine-chapel-st-peters.a443106.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![3-Hour Private Tour of Rome with Golf Cart](https://mediaim.expedia.com/localexpert/48493743/c91d173f-8133-406b-903a-ff44930c05ff.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3-Hour Private Tour of Rome with Golf Cart 4h 10/10 2 reviews Free cancellation available £162 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/3-hour-private-tour-of-rome-with-golf-cart.a48493743.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Explore the Best Highlights of Rome by Golf Car - Private Tour](https://mediaim.expedia.com/localexpert/44949953/34eea4bd-6af8-42f9-9cf2-b5d55a756401.jpg?impolicy=resizecrop&rw=500&rh=280) ### Explore the Best Highlights of Rome by Golf Car - Private Tour 2h 30m 10/10 5 reviews Free cancellation available £87 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/explore-the-best-highlights-of-rome-by-golf-car-private-tour.a44949953.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour](https://mediaim.expedia.com/localexpert/510394/0f88bc01-d5af-4cd9-b641-05324785210f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour 3h 7.8/10 6 reviews Free cancellation available £154£77 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-sistine-chapel-semi-private-tour.a510394.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Jubilee Tour of the Four Holy Doors](https://mediaim.expedia.com/localexpert/50214483/bce00857-1896-4e3f-90a2-254c2e277fd9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Jubilee Tour of the Four Holy Doors 4h Free cancellation available £279 includes taxes & fees per traveller\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/jubilee-tour-of-the-four-holy-doors.a50214483.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People](https://mediaim.expedia.com/localexpert/483840/35830ea5-5b4f-47fa-861a-b9cfcb8ecaa1.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People 3h 9.6/10 5 reviews Free cancellation available £165 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-colosseum-forum-palatine-hill-with-virtual-reality.a483840.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Semi Private Vatican Museums and Sistine Chapel Morning Tour](https://mediaim.expedia.com/localexpert/634111/5ac7b6f6-e7ae-4df7-8027-6b8cb1730b93.jpg?impolicy=resizecrop&rw=500&rh=280) ### Semi Private Vatican Museums and Sistine Chapel Morning Tour 3h 6/10 2 reviews Free cancellation available £127 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-semi-private-vatican-tour.a634111.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Appian Way, Aqueducts, & Catacombs E-Bike Guided Tour](https://mediaim.expedia.com/localexpert/44632096/6eec54cd-81da-4fa5-bbcf-8ae497b25aea.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Appian Way, Aqueducts, & Catacombs E-Bike Guided Tour 3h 30m 10/10 2 reviews Free cancellation available £62 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/appian-way-aqueducts-catacombs-safe-e-bike-tour.a44632096.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Vespa Sidecar Tour By Night with Pickup](https://mediaim.expedia.com/localexpert/1132962/5427f2ed-6f49-4595-8a30-890b1ec3420a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vespa Sidecar Tour By Night with Pickup 3h 10/10 16 reviews Free cancellation available £131£117 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/vespa-sidecar-tour-by-night-with-pickup.a1132962.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes](https://mediaim.expedia.com/localexpert/49212559/08ea0988-f7fb-4d6c-82a1-3d59b0b4662f.jpg?impolicy=resizecrop&rw=500&rh=280) ### In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes 1h Free cancellation available £22 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/in-depth-private-or-shared-tour-of-st-peters-basilica-square-grottoes.a49212559.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Attractions [See all 16 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=Attractions) ![Skip the Line: Vatican Museums & Sistine Chapel Tickets or Tours](https://mediaim.expedia.com/localexpert/490292/454636b9-24b4-49a9-aa16-c4a18321ca1e.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip the Line: Vatican Museums & Sistine Chapel Tickets or Tours 2h 30m+ 8.8/10 1,003 reviews Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-tickets-or-tours.a490292.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide](https://mediaim.expedia.com/localexpert/166616/f2175269-46b3-43bb-ace2-8a45a3aa1950.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide 1h 7.4/10 952 reviews Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-admission-with-audio-guide.a166616.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Papal Audience with Pope Leo XIV – Vatican Blessing Tour](https://mediaim.expedia.com/localexpert/166516/524a5106-2137-42b9-ae55-e253ac9b7576.jpg?impolicy=resizecrop&rw=500&rh=280) ### Papal Audience with Pope Leo XIV – Vatican Blessing Tour 4h 30m 6.6/10 178 reviews Free cancellation available £31 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/papal-audience-with-pope-francis-in-vatican-city.a166516.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Best of Rome Pass](https://mediaim.expedia.com/localexpert/500358/c70a5bbe-388f-4e0f-8419-537215ef47e3.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Best of Rome Pass 3d 7.4/10 36 reviews £92 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/best-of-rome-pass-all-access-pass-with-reserved-entrance.a500358.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Colosseum Arena, Roman Forum & Palatine Hill Tickets](https://mediaim.expedia.com/localexpert/50005920/e10a97ef-450b-48b5-8c57-6e6315ff52f5.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Colosseum Arena, Roman Forum & Palatine Hill Tickets 4h 10/10 1 review £36 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-colosseum-tickets.a50005920.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Roma Pass: Official City Card with Transport](https://mediaim.expedia.com/localexpert/4517067/549c1e1f-6d00-491a-870b-371a05fb257b.jpg?impolicy=resizecrop&rw=500&rh=280) ### Roma Pass: Official City Card with Transport 4/10 6 reviews Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/roma-pass-48-hour-city-card-with-transport.a4517067.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Reserved entrance: Vatican Museums Tickets with Hosted Entry](https://mediaim.expedia.com/localexpert/500360/b5cf98dc-7f60-4909-a877-fb3e58718a86.jpg?impolicy=resizecrop&rw=500&rh=280) ### Reserved entrance: Vatican Museums Tickets with Hosted Entry 3h+ 7.4/10 24 reviews £63 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/reserved-entrance-vatican-museums-tickets-with-hosted-entry.a500360.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip-the-Line: Vatican Museums & Sistine Chapel Ticket with Audio Guide](https://mediaim.expedia.com/localexpert/47322589/ba90951a-4535-41c7-bf61-398747b98f5c.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line: Vatican Museums & Sistine Chapel Ticket with Audio Guide 1h 30m Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-ticket-with-audio-guide.a47322589.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Arena of Colosseum, Roman Forum and Palatine Hill with Multimedia Video](https://mediaim.expedia.com/localexpert/44938942/29c8e2c5-94d4-4312-9fec-16c04a28cb1a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Arena of Colosseum, Roman Forum and Palatine Hill with Multimedia Video 4h 8/10 1 review £42 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-with-arena-skip-the-line-entrance.a44938942.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Vatican and Rome Experience Pass](https://mediaim.expedia.com/localexpert/2658880/0236f7ba-8527-4f7b-afd6-ad08df5cf0ea.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican and Rome Experience Pass 3d £97 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vatican-and-rome-experience-pass.a2658880.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Shows & concerts [See all 14 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=ShowsConcerts) ![Welcome To Rome Experience](https://mediaim.expedia.com/localexpert/1204768/f67f84b2-5a83-4c7e-bdb8-758208cb641a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Welcome To Rome Experience 1h 9.4/10 3 reviews Free cancellation available £16 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/welcome-to-rome-experience.a1204768.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: "The Most Beautiful Opera Arias" Concert](https://mediaim.expedia.com/localexpert/4776930/098e10b5-5856-406b-aa22-3fb0421e6cfa.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: "The Most Beautiful Opera Arias" Concert 50m 8/10 22 reviews Free cancellation available £30 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-the-most-beautiful-opera-arias-concert.a4776930.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: The Four Seasons by Vivaldi](https://mediaim.expedia.com/localexpert/48277050/32c6d872-9865-456a-8d74-7e55bdc1739a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: The Four Seasons by Vivaldi 1h 20m Free cancellation available £26 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-four-seasons-by-vivaldi-chiesa-evangelica-metodista.a48277050.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Italian Opera Concert and Traditional Dinner](https://mediaim.expedia.com/localexpert/47875709/00ed299e-8a03-42a0-be5d-511dea604617.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Italian Opera Concert and Traditional Dinner 2h 6/10 1 review Free cancellation available £70 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-italian-opera-concert-and-traditional-dinner.a47875709.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: IKONO Roma Immersive Experience Entry Ticket](https://mediaim.expedia.com/localexpert/47970210/44b61fdc-9ebd-4669-865d-0d09c924f3e8.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: IKONO Roma Immersive Experience Entry Ticket 1h Free cancellation available £16 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-ikono-roma-immersive-experience-entry-ticket.a47970210.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![A night at Opera Experience](https://mediaim.expedia.com/localexpert/571987/83a9ab83-eabb-461c-9388-89bdaab51ef9.jpg?impolicy=resizecrop&rw=500&rh=280) ### A night at Opera Experience 3h Free cancellation available £31 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/a-night-at-opera-experience.a571987.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![The Great Opera Arias Concert at Palazzo Poli - Trevi Fountain](https://mediaim.expedia.com/localexpert/786644/0ebd1e49-d615-49f1-97a7-ec7b1206627b.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Great Opera Arias Concert at Palazzo Poli - Trevi Fountain 1h 9.6/10 3 reviews Free cancellation available £35 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-great-opera-arias-concert-ticket-at-palazzo-santa-chiara.a786644.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Freddie Mercury Opera Show in Rome](https://mediaim.expedia.com/localexpert/49782161/c0871b11-8acb-409f-9cdb-aa90cfe79353.jpg?impolicy=resizecrop&rw=500&rh=280) ### Freddie Mercury Opera Show in Rome 1h Free cancellation available £37 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/freddie-mercury-opera-show-in-rome.a49782161.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![The Three Tenors Concert in St. Paul's Within the Walls](https://mediaim.expedia.com/localexpert/733801/b6197d60-fcfa-459b-903c-8488e16b7072.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Three Tenors Concert in St. Paul's Within the Walls 2h 10/10 7 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-three-tenors-concert-in-st-pauls-within-the-walls.a733801.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![La Traviata The Original Opera with Ballet](https://mediaim.expedia.com/localexpert/728499/bbb4e1fa-01b8-4d1e-954b-fc9873da347c.jpg?impolicy=resizecrop&rw=500&rh=280) ### La Traviata The Original Opera with Ballet 2h 8/10 4 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/la-traviata-the-original-opera-with-ballet.a728499.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Popular places to visit ![Rome showing a bridge as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193344-Ponte-Vittorio-Emanuele-Ii.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Vittorio Emanuele II Bridge Spectacular works of art adorn the balustrades and columns of this iconic bridge, which lies beside the ruins of its predecessor. [](https://expedia.co.uk/Vittorio-Emanuele-II-Bridge-Rome.d553248631901838794.Attraction) ![Auditorium Conciliazione](https://mediaim.expedia.com/destination/1/2e144f40516d4dd77392ad8b74bbfef2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Auditorium Conciliazione Enjoy a performance at Auditorium Conciliazione, a theatre with a story to tell in Rome. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.co.uk/Auditorium-Conciliazione-Rome.d6146731.Attraction) ![Ponte Sant'Angelo](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193267-Ponte-Santangelo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ponte Sant'Angelo As you cross this historic bridge take in the elegance of it statues, gaze across the River Tiber and consider the pilgrims that walked over the bridge throughout the centuries. [](https://expedia.co.uk/Ponte-SantAngelo-Rome.d508650.Attraction) ![Via Giulia](https://mediaim.expedia.com/destination/2/f3bb1970597e7675d44cb034a44f9ddc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Via Giulia During your visit to Rome, you can enjoy retail therapy at Via Giulia. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Via-Giulia-Rome-City-Centre.d6147065.Attraction) ![Castel Sant\'Angelo featuring a castle](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193341-Castel-Santangelo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Castel Sant'Angelo Explore the different layers of history, admire the intricate artwork and frescos or just take in the sweeping views of Rome from this riverside fortress. [](https://expedia.co.uk/Castel-SantAngelo-Rome-City-Centre.d502475.Attraction) #### Accademia di Storia dell‘Arte Sanitaria You can study the exhibits at Accademia di Storia dell‘Arte Sanitaria, a museum with a story of its own, during your trip to Rome. Amble around this vibrant area's riverfront or experience its acclaimed theatre scene. [](https://expedia.co.uk/Museo-Storico-Nazionale-DellArte-Sanitaria-Rome.d553248621532956071.Attraction) * * * ## Top Hotel Deals ## Check availability on hotels close to Santo Spirito Hospital [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-28&endDate=2025-09-29) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-28&endDate=2025-09-29)[28 Sept - 29 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-28&endDate=2025-09-29) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-29&endDate=2025-09-30) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-29&endDate=2025-09-30) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-29&endDate=2025-09-30) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-09-29&endDate=2025-09-30)[29 Sept - 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[Golf Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Golf-Hotels.0-n553248633938945217-0-tGolfHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Historic-Hotel.0-n553248633938945217-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels Suites in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-Suites.0-n553248633938945217-0-thotelsuites.Travel-Guide-Filter-Hotels) - [Hotels with Airport Transfers in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-With-Airport-Transfers.0-n553248633938945217-0-thotelwithairporttransfers.Travel-Guide-Filter-Hotels) - [Hotels with Babysitting Services in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-With-Babysitting-Services.0-n553248633938945217-0-thotelwithbabysittingservices.Travel-Guide-Filter-Hotels) - [Hotels with Breakfast in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-With-Breakfast.0-n553248633938945217-0-thotelwithbreakfast.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-With-Early-Check-In.0-n553248633938945217-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with Gym in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotel-With-Gym.0-n553248633938945217-0-thotelwithgym.Travel-Guide-Filter-Hotels) - [Hotels with Balcony in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotels-With-Balcony.0-n553248633938945217-0-tHotelswithBalcony.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotels-With-Hot-Tubs.0-n553248633938945217-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Hotels-With-Pool.0-n553248633938945217-0-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Luxury-Hotel.0-n553248633938945217-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Pet-Friendly-Hotel.0-n553248633938945217-0-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Romantic-Hotel.0-n553248633938945217-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Small Luxury Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Small-Luxury-Hotels.0-n553248633938945217-0--bSmallLuxuryHotels.Travel-Guide-Filter-Hotels) - [Spa Hotels in Rome City Centre](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels-Spa-Hotels.0-n553248633938945217-0-tSpaHotels.Travel-Guide-Filter-Hotels) - [Rome City Centre Hotels](https://www.expedia.co.uk/Rome-City-Centre-Rome-Hotels.0-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [Rome Historic Centre Hotels](https://www.expedia.co.uk/Rome-Historic-Centre-Rome-Hotels.0-n6200441-0.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Rome](https://www.expedia.co.uk/Rome-Hotels-Beach-Hotels.0-0-d179899-tBeachHotels.Travel-Guide-Filter-Hotels) - 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[Fountain of the Four Rivers](https://www.expedia.co.uk/Fountain-Of-The-Four-Rivers-Rome-City-Centre.d6074024.Attraction) - [Galleria Lorcan O'Neill](https://www.expedia.co.uk/Galleria-Lorcan-ONeill-Rome-City-Centre.d553248621533001887.Attraction) - [Largo di Torre Argentina](https://www.expedia.co.uk/Largo-Di-Torre-Argentina-Rome-City-Centre.d6146991.Attraction) - [Museo Mario Praz](https://www.expedia.co.uk/Museo-Mario-Praz-Rome-City-Centre.d6146965.Attraction) - [Palazzo della Cancelleria](https://www.expedia.co.uk/Palazzo-Della-Cancelleria-Rome-City-Centre.d6074078.Attraction) - [Palazzo Farnese](https://www.expedia.co.uk/Palazzo-Farnese-Rome-City-Centre.d6074084.Attraction) - [Palazzo Montecitorio](https://www.expedia.co.uk/Palazzo-Montecitorio-Rome-City-Centre.d6074092.Attraction) - [Palazzo Spada](https://www.expedia.co.uk/Palazzo-Spada-Rome-City-Centre.d502474.Attraction) - [Pantheon](https://www.expedia.co.uk/Pantheon-Rome-City-Centre.d502483.Attraction) - [Passetto di Borgo](https://www.expedia.co.uk/Passetto-Di-Borgo-Vatican.d553248633928518790.Attraction) - [Paul VI Audience Hall](https://www.expedia.co.uk/Paul-VI-Audience-Hall-Vatican.d6116036.Attraction) - [Piazza del Parlamento](https://www.expedia.co.uk/Piazza-Del-Parlamento-Rome-City-Centre.d6146718.Attraction) - [Piazza della Rotonda](https://www.expedia.co.uk/Piazza-Della-Rotonda-Rome-City-Centre.d6074100.Attraction) - [Piazza Navona](https://www.expedia.co.uk/Piazza-Navona-Rome-City-Centre.d508631.Attraction) - [Piazza Paganica](https://www.expedia.co.uk/Piazza-Paganica-Rome-City-Centre.d553248621532501075.Attraction) - [Ponte Sisto](https://www.expedia.co.uk/Ponte-Sisto-Rome-City-Centre.d6146683.Attraction) - [Roman Jewish Ghetto](https://www.expedia.co.uk/Roman-Jewish-Ghetto-Rome-City-Centre.d553248621563224986.Attraction) - [Visit Borgo](https://www.expedia.co.uk/Rome-Borgo.dx553248635976381643) - [Rome City Centre Holidays](https://www.expedia.co.uk/Rome-City-Centre.d553248633938945217.Holidays-City-Breaks) - [Visit Navona](https://www.expedia.co.uk/Rome-Navona.dx6051981) - [Visit Parione](https://www.expedia.co.uk/Rome-Parione.dx553248635976382117) - [Visit Rome City Centre](https://www.expedia.co.uk/Rome-Rome-City-Centre.dx553248633938945217) - [Rome Holidays](https://www.expedia.co.uk/Rome.d179899.Holidays-City-Breaks) - [San Luigi dei Francesi](https://www.expedia.co.uk/San-Luigi-Dei-Francesi-Rome-City-Centre.d6074112.Attraction) - [Vatican Holidays](https://www.expedia.co.uk/Vatican.d6046253.Holidays-City-Breaks) - [Via dei Coronari](https://www.expedia.co.uk/Via-Dei-Coronari-Rome-City-Centre.d553248621532500864.Attraction) - [Via Giulia](https://www.expedia.co.uk/Via-Giulia-Rome-City-Centre.d6147065.Attraction) - [Villa Farnesina](https://www.expedia.co.uk/Villa-Farnesina-Rome-City-Centre.d6074168.Attraction) - [All inclusive Holiday Packages Rome](https://www.expedia.co.uk/lp/theme-holidays/all-inclusive-holidays/179899/Rome) - [Compact Car Hire near Piazza Navona](https://www.expedia.co.uk/Compact-Car-Rentals-In-Piazza-Navona.d508631-tCompact.Car-Rental-Guide-Class) - [Car hire near Castel Sant'Angelo](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Castel-SantAngelo.d502475.Car-Hire-Guide) - [Car hire near Piazza Navona](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Piazza-Navona.d508631.Car-Hire-Guide) - [Car hire near Rome City Centre](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Rome-City-Centre.d553248633938945217.Car-Hire-Guide) - [Things to do in Rome](https://www.expedia.co.uk/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)