Title: Santo Spirito Hospital in Rome City Centre | Expedia.co.uk [Santo Spirito Hospital Hotels](https://expedia.co.uk/Santo-Spirito-Hospital-Hotels.0-l6227560-0.Travel-Guide-Filter-Hotels)[Santo Spirito Hospital Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santo-Spirito-Hospital.d6227560.Car-Hire-Guide)[Rome City Centre Holidays](https://expedia.co.uk/Rome-City-Centre.d553248633938945217.Holidays-City-Breaks) # Santo Spirito Hospital ## Visit Santo Spirito Hospital Activities --- --- ## Plan a trip to see Santo Spirito Hospital Price found within the past 48 hours. Click for updated prices. ![Hotel Delle Civette](https://images.trvl-media.com/lodging/101000000/100970000/100969400/100969343/098779c1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Delle Civette Nomentano Save 100% on your flight £247 per person 9 Feb - 12 Feb found 1 day ago Return flight included Birmingham (BHX) to Rome (FCO) 9.6/10 Exceptional! (267 reviews) Breakfast was fresh and healthy each morning. All of the staff were extremely nice and helpful. Loved my stay here, would stay here again and will recommend to friends. Reviewed on 28 Dec 2025 ![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/aa8b51a2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais de la Poste Rome City Centre £664 per person 1 Mar - 7 Mar found 19 hours ago Return flight included London (LHR) to Rome (FCO) 9.2/10 Wonderful! (612 reviews) Clean room friendly staff Reviewed on 12 Dec 2025 ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/6b9ee00e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio £598 per person 15 Feb - 22 Feb found 15 hours ago Return flight included Birmingham (BHX) to Rome (FCO) 9.6/10 Exceptional! (335 reviews) Wonderful stay, would be back Reviewed on 16 Dec 2025 ### Tours & day trips [See all 398 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=ToursDayTrips) ![Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour](https://mediaim.expedia.com/localexpert/166597/4f9bb377-01c6-4b8f-980f-7747e7f07a85.jpg?impolicy=resizecrop&rw=500&rh=280) ### Vatican Museums, Sistine Chapel, & St. Peter’s Basilica Fully Guided Tour 2h+ 9/10 6,557 reviews Free cancellation available £69 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/vatican-museums-sistine-chapel-st-peters-basilica-fully-guided-tour.a166597.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill](https://mediaim.expedia.com/localexpert/166587/4edbea50-914d-4144-a851-55e98d3e0a1f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum & Ancient Rome Guided Tour with Roman Forum & Palatine Hill 3h 9.2/10 3,910 reviews Free cancellation available £56 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-ancient-rome-guided-tour-with-roman-forum-palatine-hill.a166587.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour](https://mediaim.expedia.com/localexpert/3138351/99f75742-d99d-48ce-8246-922f96cce825.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour 2h 30m 8.4/10 259 reviews Free cancellation available £26 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-colosseum-with-arena-roman-forum-and-palatine-guided-tour.a3138351.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Pompeii, Amalfi Coast and Positano Day Trip from Rome](https://mediaim.expedia.com/localexpert/442250/aa41f01e-adac-4892-9511-7475ae5b39d6.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pompeii, Amalfi Coast and Positano Day Trip from Rome 13h 9.2/10 460 reviews Free cancellation available £82 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-positano-day-trip-from-rome.a442250.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Gems of Tuscany: Florence & Pisa One Day Excursion from Rome](https://mediaim.expedia.com/localexpert/2461139/37393bb8-a798-4b51-a70b-513eb050f654.jpg?impolicy=resizecrop&rw=500&rh=280) ### Gems of Tuscany: Florence & Pisa One Day Excursion from Rome 14h 8.8/10 63 reviews Free cancellation available £130 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/gems-of-tuscany-florence-pisa-1-day-excursion-from-rome.a2461139.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option](https://mediaim.expedia.com/localexpert/238327/66f41112-0db2-4e77-9ec7-cb838b38abe8.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Sorrento & Amalfi Coast with Pompeii or Positano Option 12h 9.2/10 113 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pompeii-amalfi-coast-and-sorrento-day-trip-from-rome.a238327.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Colosseum Underground & Ancient Rome Guided Tour](https://mediaim.expedia.com/localexpert/3087492/c7df9e4a-f554-401b-b44f-9b6b8cfbc8c5.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Underground & Ancient Rome Guided Tour 3h 9.4/10 28 reviews £54 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-vip-colosseum-underground-ancie.a3087492.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting](https://mediaim.expedia.com/localexpert/166552/04a98a7b-1b9b-4323-933f-1da13e16b5ee.jpg?impolicy=resizecrop&rw=500&rh=280) ### From Rome: Tuscany & Montepulciano Day Trip including Lunch & Wine Tasting 11h 9.6/10 969 reviews Free cancellation available £73 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/from-rome-tuscany-montepulciano-day-trip-including-lunch-wine-tasting.a166552.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Trevi Fountain Undergound Domus Guided Tour](https://mediaim.expedia.com/localexpert/49601875/96a70552-3681-4cd4-9960-896373b17894.jpg?impolicy=resizecrop&rw=500&rh=280) ### Trevi Fountain Undergound Domus Guided Tour 1h+ 9.2/10 25 reviews Free cancellation available £33 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/trevi-fountain-undergound-domus-guided-tour.a49601875.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Private & custom tours [See all 84 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=Privatecustomtours) ![Fiat 500 Vintage Car Tour in Rome with Professional Photographer](https://mediaim.expedia.com/localexpert/49942107/1bf7d0f6-fc82-426a-a26c-7b7fbb1160df.jpg?impolicy=resizecrop&rw=500&rh=280) ### Fiat 500 Vintage Car Tour in Rome with Professional Photographer 1h 30m Free cancellation available £74 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/fiat-500-vintage-car-tour-in-rome-with-professional-photographer.a49942107.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![3-Hour Private Tour of Rome with Golf Cart](https://mediaim.expedia.com/localexpert/48493743/c91d173f-8133-406b-903a-ff44930c05ff.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3-Hour Private Tour of Rome with Golf Cart 4h 10/10 4 reviews Free cancellation available £161 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/3-hour-private-tour-of-rome-with-golf-cart.a48493743.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Explore the Best Highlights of Rome by Golf Car - Private Tour](https://mediaim.expedia.com/localexpert/44949953/34eea4bd-6af8-42f9-9cf2-b5d55a756401.jpg?impolicy=resizecrop&rw=500&rh=280) ### Explore the Best Highlights of Rome by Golf Car - Private Tour 2h 30m 9.8/10 7 reviews Free cancellation available £60 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/explore-the-best-highlights-of-rome-by-golf-car-private-tour.a44949953.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes](https://mediaim.expedia.com/localexpert/49212559/08ea0988-f7fb-4d6c-82a1-3d59b0b4662f.jpg?impolicy=resizecrop&rw=500&rh=280) ### In-depth Private or Shared Tour of St. Peter's Basilica, Square, & Grottoes 1h Free cancellation available £22 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/in-depth-private-or-shared-tour-of-st-peters-basilica-square-grottoes.a49212559.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Horse Sanctuary & Trail Ride in Ostia Antica](https://mediaim.expedia.com/localexpert/1146828/c40f4d5d-dc3c-4515-9e10-bc97cb1a8c82.jpg?impolicy=resizecrop&rw=500&rh=280) ### Horse Sanctuary & Trail Ride in Ostia Antica 3h 10/10 4 reviews Free cancellation available £77 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/horse-riding-trail-in-ancient-rome.a1146828.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour](https://mediaim.expedia.com/localexpert/510394/0f88bc01-d5af-4cd9-b641-05324785210f.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line Vatican, Sistine Chapel Semi-Private Tour 3h 7.8/10 6 reviews Free cancellation available ~~£225~~£126 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-sistine-chapel-semi-private-tour.a510394.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People](https://mediaim.expedia.com/localexpert/483840/35830ea5-5b4f-47fa-861a-b9cfcb8ecaa1.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Arena Floor & Ancient Rome Semi Private Max 6 People 3h 9.6/10 5 reviews Free cancellation available £165 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-arena-floor-ancient-rome-semi-private-max-6-people.a483840.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Private or Small Group Tour of Ostia Antica with Transfer from Rome](https://mediaim.expedia.com/localexpert/49448519/3885d51e-bbd6-4d9d-b70d-58217e61d4d8.jpg?impolicy=resizecrop&rw=500&rh=280) ### Private or Small Group Tour of Ostia Antica with Transfer from Rome 2h 30m Free cancellation available £217 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/private-or-small-group-tour-of-ostia-antica-with-transfer-from-rome.a49448519.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Highlights by Golf Cart: Private Tour](https://mediaim.expedia.com/localexpert/3617993/b5276f03-5ba6-4fd2-8d67-43236d876bf9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Highlights by Golf Cart: Private Tour 7h 9.6/10 15 reviews Free cancellation available £314 includes taxes & fees per adult\* \*Get lower prices by selecting more than 2 adults [](https://www.expedia.co.uk/things-to-do/rome-by-golf-cart-private-tour.a3617993.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome's Hidden Excavations: Underground Tunnels & Colosseum Tour](https://mediaim.expedia.com/localexpert/2126119/a48faaba-5051-4924-b519-53cceb3c80d1.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome's Hidden Excavations: Underground Tunnels & Colosseum Tour 4h Free cancellation available £78 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/1-hour-colosseum-exclusive-private-guided-tour-no-line-pickup-drop-off-option.a2126119.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Food, drink & nightlife [See all 78 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=FoodDrinkNightlife) ![3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu](https://mediaim.expedia.com/localexpert/2128072/99424690-45a6-41c0-80b9-d6dd8583fa44.jpg?impolicy=resizecrop&rw=500&rh=280) ### 3 in 1 Cooking Class near Navona: Fettuccine, Ravioli & Tiramisu 3h 9.6/10 62 reviews Free cancellation available ~~£61~~£51 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/3-in-1-cooking-class-piazza-navona-fettuccine-ravioli-and-tiramisu.a2128072.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Learn to Make Pasta & Tiramisu with Wine and Limoncello Included](https://mediaim.expedia.com/localexpert/3087530/f87dc754-fe4a-40ab-968b-33ecea2028d9.jpg?impolicy=resizecrop&rw=500&rh=280) ### Learn to Make Pasta & Tiramisu with Wine and Limoncello Included 2h 9.8/10 25 reviews Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-cooking-class-fettuccine-tiramisu-lovers-workshop.a3087530.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour](https://mediaim.expedia.com/localexpert/166608/8447e5f4-3c26-475b-beb8-84f570ef6336.jpg?impolicy=resizecrop&rw=500&rh=280) ### VIP Vatican Breakfast with Vatican Museums & Sistine Chapel Guided Tour 3h 9.2/10 105 reviews £104 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/vip-vatican-breakfast-sistine-chapel-and-st-peters-basilica-guided-tour.a166608.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine](https://mediaim.expedia.com/localexpert/1088407/cc51bcb9-036a-433d-adde-e731983a97fc.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Hidden Gems of Trastevere with Dinner & Wine 3h 9.2/10 23 reviews Free cancellation available £74 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/hidden-rome-food-tour-in-trastevere-with-dinner-and-wine.a1088407.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Pasta-Making Class: Cook, Dine & Drink With A Local Chef](https://mediaim.expedia.com/localexpert/263177/9645d4ca-bc3b-415f-961c-d17a85c73f7c.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pasta-Making Class: Cook, Dine & Drink With A Local Chef 3h 10/10 131 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pasta-making-class-cook-dine-drink-with-a-local-chef.a263177.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Street Food Tour with Local Guide](https://mediaim.expedia.com/localexpert/2124035/14fd9e77-2f7a-4a8e-86bb-f26685ffa41a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Street Food Tour with Local Guide 2h 30m 10/10 11 reviews Free cancellation available £39 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-street-food-tour-with-local-guide.a2124035.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Trastevere Food tour with Free-Flowing Fine Wine, Rome](https://mediaim.expedia.com/localexpert/1012380/ea071694-fbc0-45bf-b793-013e9ed83055.jpg?impolicy=resizecrop&rw=500&rh=280) ### Trastevere Food tour with Free-Flowing Fine Wine, Rome 4h 9.8/10 46 reviews Free cancellation available £109 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-roman-food-tour-in-trastevere-with-free-flowing-fine-wine.a1012380.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo](https://mediaim.expedia.com/localexpert/1012378/acd7e3f4-e1d1-4ca6-8f4f-73dbd81ae671.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Food Tour: Unlimited Tastings with Fine Wine & Barolo 4h 9.8/10 40 reviews Free cancellation available £60 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-food-wine-tour-in-prati.a1012378.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert](https://mediaim.expedia.com/localexpert/1182002/1cc696ba-8268-44cf-909e-72bbe3ccf7dd.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome Cooking Class: Make Pizza and Pasta with Wine & Dessert 3h 30m Free cancellation available £49 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pizza-and-pasta-master-class-with-wine-and-tiramisu-on-the-ancient-appian-way.a1182002.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Trastevere at Sunset: Rome Small Group Food & Wine Tour](https://mediaim.expedia.com/localexpert/5184945/71f924e4-29be-4efc-b2a0-e96d8c105bf4.jpg?impolicy=resizecrop&rw=500&rh=280) ### Trastevere at Sunset: Rome Small Group Food & Wine Tour 3h 30m 9.4/10 3 reviews Free cancellation available £95 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/trastevere-area-by-night-gourmet-food-wine-tasting-experience.a5184945.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Attractions [See all 16 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=Attractions) ![Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide](https://mediaim.expedia.com/localexpert/166616/f2175269-46b3-43bb-ace2-8a45a3aa1950.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip-the-Line: Vatican Museums & Sistine Chapel Admission with Audio Guide 1h 7.6/10 958 reviews Free cancellation available £43 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-admission-with-audio-guide.a166616.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Skip the Line: Vatican Museums & Sistine Chapel + Optional Basilica](https://mediaim.expedia.com/localexpert/490292/454636b9-24b4-49a9-aa16-c4a18321ca1e.jpg?impolicy=resizecrop&rw=500&rh=280) ### Skip the Line: Vatican Museums & Sistine Chapel + Optional Basilica 1h 30m+ 8.8/10 1,014 reviews Free cancellation available £44 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/skip-the-line-vatican-museums-sistine-chapel-tickets-or-tours.a490292.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Papal Audience with Pope Leo XIV – Vatican Blessing Tour](https://mediaim.expedia.com/localexpert/166516/524a5106-2137-42b9-ae55-e253ac9b7576.jpg?impolicy=resizecrop&rw=500&rh=280) ### Papal Audience with Pope Leo XIV – Vatican Blessing Tour 4h 30m 6.8/10 180 reviews Free cancellation available £31 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/papal-audience-with-pope-leo-xiv-vatican-blessing-tour.a166516.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Best of Rome Pass](https://mediaim.expedia.com/localexpert/500358/c70a5bbe-388f-4e0f-8419-537215ef47e3.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Best of Rome Pass 3d 7.2/10 36 reviews £92 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/best-of-rome-pass-all-access-pass-with-reserved-entrance.a500358.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Colosseum Roman Forum and Palatine Hill Entrance in Rome](https://mediaim.expedia.com/localexpert/50714773/308847af-92de-41ee-81c1-d21406d4e327.jpg?impolicy=resizecrop&rw=500&rh=280) ### Colosseum Roman Forum and Palatine Hill Entrance in Rome 4h £35 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/colosseum-roman-forum-and-palatine-hill-entrance-in-rome.a50714773.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Breakfast in the Vatican Museums](https://mediaim.expedia.com/localexpert/47280924/ac1284c0-1bf6-4aaf-9d51-e1ff1216e737.jpg?impolicy=resizecrop&rw=500&rh=280) ### Breakfast in the Vatican Museums 4h 8/10 1 review £74 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/breakfast-in-the-vatican-museums.a47280924.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Roma Pass: Official City Card with Transport](https://mediaim.expedia.com/localexpert/4517067/ead2a7b2-391c-408f-83ea-205d45bcc582.jpg?impolicy=resizecrop&rw=500&rh=280) ### Roma Pass: Official City Card with Transport 4/10 6 reviews Free cancellation available £48 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/roma-pass-48-hour-city-card-with-transport.a4517067.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Reserved entrance: Vatican Museums Tickets with Hosted Entry](https://mediaim.expedia.com/localexpert/500360/b5cf98dc-7f60-4909-a877-fb3e58718a86.jpg?impolicy=resizecrop&rw=500&rh=280) ### Reserved entrance: Vatican Museums Tickets with Hosted Entry 3h 7.6/10 24 reviews £63 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/reserved-entrance-vatican-museums-tickets-with-hosted-entry.a500360.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Pantheon Skip the line Ticket with audioguide App](https://mediaim.expedia.com/localexpert/49601980/a79926dd-2811-4774-a04e-43c815ba52af.jpg?impolicy=resizecrop&rw=500&rh=280) ### Pantheon Skip the line Ticket with audioguide App 1h 7/10 2 reviews Free cancellation available £10 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/pantheon-skip-the-line-ticket-with-audioguide-app.a49601980.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Palazzo Barberini experience ticket](https://mediaim.expedia.com/localexpert/49602254/575602dc-592c-435f-9c7c-c971705fe21a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Palazzo Barberini experience ticket 2h Free cancellation available £22 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/palazzo-barberini-experience-ticket.a49602254.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Shows & concerts [See all 11 activities](https://expedia.co.uk/things-to-do/search?&rid=6227560&location=Santo+Spirito+Hospital&filter.categories=ShowsConcerts) ![Welcome To Rome Experience](https://mediaim.expedia.com/localexpert/1204768/f67f84b2-5a83-4c7e-bdb8-758208cb641a.jpg?impolicy=resizecrop&rw=500&rh=280) ### Welcome To Rome Experience 1h 9.4/10 3 reviews Free cancellation available £16 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/welcome-to-rome-experience.a1204768.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![The Three Tenors Concert in St. Paul's Within the Walls](https://mediaim.expedia.com/localexpert/733801/b6197d60-fcfa-459b-903c-8488e16b7072.jpg?impolicy=resizecrop&rw=500&rh=280) ### The Three Tenors Concert in St. Paul's Within the Walls 2h 9.6/10 9 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/the-three-tenors-concert-in-st-pauls-within-the-walls.a733801.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Italian Opera Concert and Traditional Dinner](https://mediaim.expedia.com/localexpert/47875709/00ed299e-8a03-42a0-be5d-511dea604617.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Italian Opera Concert and Traditional Dinner 2h 6/10 1 review Free cancellation available £70 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-italian-opera-concert-and-traditional-dinner.a47875709.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![La Traviata The Original Opera by Giuseppe Verdi](https://mediaim.expedia.com/localexpert/728499/8e071bfa-27dc-44ae-bced-3b5a8d5e5a47.jpg?impolicy=resizecrop&rw=500&rh=280) ### La Traviata The Original Opera by Giuseppe Verdi 2h 8/10 4 reviews Free cancellation available £29 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/la-traviata-the-original-opera-with-ballet.a728499.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Rome: Chopin & Italian Friends Piano Concert](https://mediaim.expedia.com/localexpert/50006958/8da4d54f-857e-4e29-9a4b-f3e3741e948b.jpg?impolicy=resizecrop&rw=500&rh=280) ### Rome: Chopin & Italian Friends Piano Concert 50m Free cancellation available £28 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/rome-chopin-italian-friends-piano-concert.a50006958.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![Freddie Mercury Opera Show in Rome](https://mediaim.expedia.com/localexpert/49782161/c0871b11-8acb-409f-9cdb-aa90cfe79353.jpg?impolicy=resizecrop&rw=500&rh=280) ### Freddie Mercury Opera Show in Rome 1h 6/10 1 review Free cancellation available £37 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/freddie-mercury-opera-show-in-rome.a49782161.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ![A night at Opera Experience](https://mediaim.expedia.com/localexpert/571987/83a9ab83-eabb-461c-9388-89bdaab51ef9.jpg?impolicy=resizecrop&rw=500&rh=280) ### A night at Opera Experience 3h Free cancellation available £31 includes taxes & fees per adult [](https://www.expedia.co.uk/things-to-do/a-night-at-opera-experience.a571987.activity-details?&rid=6227560&location=Santo+Spirito+Hospital&swp=off) ### Popular places to visit ![Rome showing a bridge as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193344-Ponte-Vittorio-Emanuele-Ii.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Vittorio Emanuele II Bridge Spectacular works of art adorn the balustrades and columns of this iconic bridge, which lies beside the ruins of its predecessor. [](https://expedia.co.uk/Vittorio-Emanuele-II-Bridge-Rome.d553248631901838794.Attraction) ![Auditorium Conciliazione](https://mediaim.expedia.com/destination/1/2e144f40516d4dd77392ad8b74bbfef2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Auditorium Conciliazione 5/5(1 review) Enjoy a performance at Auditorium Conciliazione, a theatre with a story to tell in Rome. Stroll along the riverfront or visit the stunning cathedral in this vibrant area. [](https://expedia.co.uk/Auditorium-Conciliazione-Rome.d6146731.Attraction) ![Ponte Sant'Angelo](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193267-Ponte-Santangelo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Ponte Sant'Angelo As you cross this historic bridge take in the elegance of it statues, gaze across the River Tiber and consider the pilgrims that walked over the bridge throughout the centuries. [](https://expedia.co.uk/Ponte-SantAngelo-Rome.d508650.Attraction) ![Via Giulia](https://mediaim.expedia.com/destination/2/f3bb1970597e7675d44cb034a44f9ddc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Via Giulia During your visit to Rome, you can enjoy retail therapy at Via Giulia. While in this walkable area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Via-Giulia-Rome-City-Centre.d6147065.Attraction) ![Castel Sant\'Angelo featuring a castle](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/193000/193341-Castel-Santangelo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Castel Sant'Angelo 4.5/5(947 reviews) Explore the different layers of history, admire the intricate artwork and frescos or just take in the sweeping views of Rome from this riverside fortress. [](https://expedia.co.uk/Castel-SantAngelo-Rome-City-Centre.d502475.Attraction) #### Accademia di Storia dell‘Arte Sanitaria You can study the exhibits at Accademia di Storia dell‘Arte Sanitaria, a museum with a story of its own, during your trip to Rome. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.co.uk/Museo-Storico-Nazionale-DellArte-Sanitaria-Rome.d553248621532956071.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Santo Spirito Hospital [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-12-30&endDate=2025-12-31)[30 Dec - 31 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-12-30&endDate=2025-12-31) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-12-31&endDate=2026-01-01)[31 Dec - 1 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=2025-12-31&endDate=2026-01-01) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[2 Jan - 4 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=09%2F01%2F2026&endDate=11%2F01%2F2026)[9 Jan - 11 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6227560&startDate=09%2F01%2F2026&endDate=11%2F01%2F2026) ![Hotel Dei Mellini](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Dei Mellini Via Muzio Clementi 81 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) ![Trastevere Roma | UNA Esperienze](https://images.trvl-media.com/lodging/75000000/74060000/74055900/74055827/0d267171_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Trastevere Roma | UNA Esperienze Via Emilio Morosini 27 Rome RM [](https://expedia.co.uk/Rome-Hotels-UNAHOTELS-Trastevere-Roma.h74055827.Hotel-Information) ![Hotel Nazionale](https://images.trvl-media.com/lodging/1000000/30000/26800/26756/7b7166b0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Nazionale Piazza Montecitorio, 131 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Nazionale.h26756.Hotel-Information) ![Grand Hotel Olympic](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/a302c22a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grand Hotel Olympic Via Properzio 2/a Rome RM [](https://expedia.co.uk/Rome-Hotels-Grand-Hotel-Olympic.h72827.Hotel-Information) ![citizenM Rome Isola Tiberina](https://images.trvl-media.com/lodging/95000000/94710000/94706900/94706900/2bd1dac3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### citizenM Rome Isola Tiberina LUNGOTEVERE DE CENCI 5-8 Rome RM [](https://expedia.co.uk/Rome-Hotels-CitizenM-Rome-Isola-Tiberina.h94706900.Hotel-Information) ![Excellence Suite](https://images.trvl-media.com/lodging/15000000/14620000/14617000/14616938/5c2b5d7f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Excellence Suite Via della Purificazione 38 Rome RM [](https://expedia.co.uk/Rome-Hotels-Excellence-Suite.h14616938.Hotel-Information) ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/df3b5a06_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Quirinale Via Nazionale 7 Rome RM [](https://expedia.co.uk/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Hive Hotel Via Torino 6 Rome RM [](https://expedia.co.uk/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![Villa Agrippina Gran Meliá - The Leading Hotels of the World](https://images.trvl-media.com/lodging/5000000/4470000/4464300/4464282/7d75de4e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Villa Agrippina Gran Meliá - The Leading Hotels of the World Via del Gianicolo 3 Rome RM [](https://expedia.co.uk/Rome-Hotels-Villa-Agrippina-Gran-Melia-The-Leading-Hotels-Of-The-World.h4464282.Hotel-Information) [See all 14,919 properties in Santo Spirito Hospital](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6227560) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - [3 Star Hotels in Rome City Centre ](https://www.expedia.co.uk/3Star-Rome-City-Centre-Rome-Hotels.s30-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Navona ](https://www.expedia.co.uk/4Star-Navona-Rome-Hotels.s40-n6051981-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Rome City Centre ](https://www.expedia.co.uk/4Star-Rome-City-Centre-Rome-Hotels.s40-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Rome City Centre ](https://www.expedia.co.uk/5Star-Rome-City-Centre-Rome-Hotels.s50-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Rome ](https://www.expedia.co.uk/5Star-Rome-Hotels.s50-0-d179899.Travel-Guide-Filter-Hotels) - [Hotels near Bambino Gesu Hospital ](https://www.expedia.co.uk/Bambino-Gesu-Hospital-Hotels.0-l6159738-0.Travel-Guide-Filter-Hotels) - [Borgo Hotels ](https://www.expedia.co.uk/Borgo-Rome-Hotels.0-n553248635976381643-0.Travel-Guide-Filter-Hotels) - 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