Find hotels in Santa Lucia from £75

Where to?

Dates

April 2026

May 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Santa Lucia

Spa

Apart hotel

Our top choices for Santa Lucia hotels

Seasonal outdoor pool, open 10:00 AM to 8:00 PM, pool umbrellas

Holiday Inn Rome- Eur Parco Dei Medici by IHG

Magliana Vecchia

Canada

Vincenzo

includes taxes & fees

1 Apr - 2 Apr

Premium bedding, minibar, in-room safe, desk

Hotel Sonya

Rome City Centre

United Kingdom

Sean

Rooftop terrace

Ruby Giulia Hotel Rome

Rome City Centre

Australia

Sandra

includes taxes & fees

23 Mar - 24 Mar

Free daily full breakfast

Massimi City Garden Hotel

Trionfale

United States

Nancy

includes taxes & fees

29 Mar - 30 Mar

Couples treatment room(s), sauna, hot tub, steam room

Hotel Villa Pamphili Roma

Gianicolense Suburb

United States

Madhav

includes taxes & fees

25 Mar - 26 Mar

Terrace/patio

Hotel Smeraldo

Rome City Centre

United States

Raul

includes taxes & fees

22 Mar - 23 Mar

Front of property – evening/night

Hotel Artemide

Rome City Centre

Canada

E. JAMES

includes taxes & fees

22 Mar - 23 Mar

City view from property

Trastevere Roma | UNA Esperienze

Rome City Centre

United States

David

includes taxes & fees

24 Mar - 25 Mar

Point of interest

Bob W Rome Testaccio

Rome Historic Centre

United Kingdom

Robert

includes taxes & fees

31 Mar - 1 Apr

Bar (on property)

The Social Hub Rome

Tiburtino

Canada

Chi-Hao

includes taxes & fees

29 Mar - 30 Mar

Exterior

Hotel Abruzzi

Rome City Centre

United States

mark

includes taxes & fees

22 Mar - 23 Mar

Reception

Aparthotel Colombo Roma

Ostiense

United Kingdom

Jasmine Avery

includes taxes & fees

29 Mar - 30 Mar

Seasonal outdoor pool

A.Roma Lifestyle Hotel

Gianicolense Suburb

United States

mishael

includes taxes & fees

2 Apr - 3 Apr

Couples treatment room(s), sauna, hot tub, Turkish bath/hammam

Crowne Plaza Rome-St. Peter's Hotel & Spa by IHG

Gianicolense Suburb

Canada

Meyjorie

includes taxes & fees

29 Mar - 30 Mar

Terrace/patio

The Hoxton Rome

Salario

Finland

Jutta Emilia

includes taxes & fees

6 Apr - 7 Apr

Suite (La Dolce Vita) | View from room

Hotel Nazionale

Rome City Centre

United States

Yuqi

includes taxes & fees

23 Mar - 24 Mar

Daily buffet breakfast (EUR 8.00 per person)

Warmthotel

Fonte Ostiense

United States

majed

includes taxes & fees

23 Mar - 24 Mar

Rooftop terrace

citizenM Rome Isola Tiberina

Rome City Centre

United Kingdom

Clare

includes taxes & fees

22 Mar - 23 Mar

Property entrance

Hotel Pacific Roma

Vatican

United States

Adrienne

includes taxes & fees

17 Apr - 18 Apr

City view

UNA Hotels Decò Roma

Rome City Centre

United Kingdom

Philip

includes taxes & fees

22 Mar - 23 Mar

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign up, it's free

Top Santa Lucia Hotel Reviews

Excellence Suite

Excellence Suite

10/10 Excellent

"Very clean, newly remodeled room . Very nice well maintained property . Excellent location close to everything . . Very helpful front dest . Woud stay there again "

Hotel Artemide

Hotel Artemide

10/10 Excellent

"The good reviews are true. Hotel Artemide is a wonderful place to stay when visiting Rome. A few highlights - Sebastian at the front desk was amazing and helped us with a room upgrade The hotel has a daily breakfast buffet that is above and beyond. Wonderful food selection but made even better by their fun, outgoing and helpful staff that get to know you personally and are so kind They have a spa and it’s quite wonderful. We did a 150 min spa treatment that included massage and facials as well as time to soak in the jacuzzi, sweat in the sauna and relax with a tea before enjoying our massage The housekeeping are friendly and helpful. The refrigerator in your room is stocked daily, free of charge. Amazing! They have a lovely rooftop bar, where you get a voucher to visit when you check in We highly recommend the Hotel Artemide for your vacation in Rome!"

The Hoxton Rome

The Hoxton Rome

10/10 Excellent

"Nicely designed hotel in a location outside of the central tourist area. Lots of nearby restaurants to dine in. Hotel lounge was cozy and comfortable for work or play. Special shout out to Michael at the front desk who assisted with the private transportation to the airport when there were numerous flight delays! Thank you!"

The Social Hub Rome

The Social Hub Rome

6/10 Okay

"The gym was amazing! Lots of space and weights. The rooms were super clean. The staff on the other hand were not the best. I was in my room taking a nap around 1pm and my door kept knocking. I was in there alone and I had forgotten to put the DND sign up. I told them I did not need cleaning, so they eventually went away. At 2:30 they came back and knocked again and I yelled again I did not need it( I was exhausted). They instead yelled POLIZIA!! So I got worried and went to get the door. As I opened it, it was the cleaning lady. I’m like, “why would you yell polizia if it’s just you, I’m sleeping and I’m tired”. She then is like “I’m so sorry, I’m so sorry”. That whole scenario was scary for a woman traveling alone. I went to go report it & nothing was done. A different day, I went to go buy some pizza and the staff there had such an attitude."

More cheap stays in Santa Lucia

Hotel Touring

Hotel Touring

Via Principe Amedeo 2 Rome RM

£82

23 Mar - 24 Mar

includes taxes & fees

7.4/10 Good! (977 reviews)

Frequently asked questions

What is the best area to stay in Santa Lucia?

The best area to stay in Santa Lucia is around the historic centre, particularly near Piazza della Repubblica and along Via del Corso.

This central area is the main attraction for visitors, offering a good mix of historic sites and modern conveniences. Key landmarks like the ancient Roman Theatre and the Church of San Giovanni are just a short walk away. The streets here are generally pedestrian-friendly, making it easy to explore on foot.

Couples often find this area superb for a romantic getaway. The evenings are particularly pleasant, with many restaurants offering outdoor dining and the opportunity for a leisurely stroll through the well-lit historic streets. The proximity to the Santa Lucia train station also makes day trips to nearby towns straightforward.

For those looking for a slightly more peaceful stay while still being central, the streets just off Piazza della Repubblica, towards the Villa Comunale gardens, are an excellent option.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Lucia.

How can I save on a Santa Lucia hotel booking with Expedia?

Members always get our best prices. Find our best Santa Lucia hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

How much is the nightly rate at a Santa Lucia hotel?

Prices for hotels in Santa Lucia often vary, but you can find a great deal from £75 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Book Hotels in Santa Lucia on Expedia.it

Go further with the Expedia app

Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app

QR code to download the app

2bd6c518-6457-4412-b5e1-763677aaae5d22b1730a-4210-4d4b-9a05-e7bc538974e8