Title: The Best Hotels in Otay Mesa West, San Diego - 2025 Updated Prices | Expedia.co.uk [Otay Mesa West Travel Guide](https://expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010)[Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Otay-Mesa-West.d553248625809641010.Car-Hire-Guide)[Otay Mesa West Holidays](https://expedia.co.uk/Otay-Mesa-West.d553248625809641010.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Otay Mesa West, San Diego ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Otay Mesa West Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=APART_HOTEL) Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&amenities=SPA_ON_SITE) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=HOTEL_RESORT) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&travelerType=family_friendly) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&amenities=OCEAN_VIEW) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&amenities=HOT_TUB) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=CONDO) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=VILLA) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&lodging=COTTAGE) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Otay+Mesa+West%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248625809641010&latLong=32.577585%2C-117.054421&adults=2&startDate=2025-10-02&d1=2025-10-02&endDate=2025-10-04&d2=2025-10-04&amenities=PETS) ## Check prices for these dates Tonight [18 Sept - 19 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-09-18&endDate=2025-09-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-09-19&endDate=2025-09-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Otay Mesa West, San Diego ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/dd3cca67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/63587042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Gaslamp Quarter, 11.2 mi from Otay Mesa West 8.8/10 Excellent (1795) "Awesome place!!! " £81 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/7f3bc7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside 11.9 mi from Otay Mesa West 8.4/10 Very good (5951) "Great place to stay!!!!" £148 includes taxes & fees 25 Sept - 26 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel 6.5 mi from Otay Mesa West 9.2/10 Wonderful (3300) "Good place to stay" £108 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/ce3fee83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/93444558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/e3d5bf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/c6debcd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horton Grand, Downtown/Gaslamp Quarter 11.1 mi from Otay Mesa West 9.0/10 Wonderful (2550) "Beautiful Boutique Hotel" £133 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/112e5b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter East Village, 10.9 mi from Otay Mesa West 9.2/10 Wonderful (390) "Great place to stay!" £174 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/7e147d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/60472bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/23e38216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel San Diego Gaslamp Quarter, 10.9 mi from Otay Mesa West 9.0/10 Wonderful (2927) "Great hotel" £201 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/5500/5441/01fc7c7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5500/5441/80bcbba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/5500/5441/bda3c55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5500/5441/49db9dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Suites Hotel Coronado Island 10.7 mi from Otay Mesa West 8.8/10 Excellent (1008) "Location was convenient, rooms were spacious. Staff was kind. " £167 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Coronado-Hotels-Best-Western-Plus-Suites-Hotel-Coronado-Island.h5441.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/e3befa7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a9bcd444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter Gaslamp Quarter, 11 mi from Otay Mesa West 9.0/10 Wonderful (1121) "Great stay! " £137 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/5feb0059.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/aeb717a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/30e922d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/5000/4926/7a33c92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham El Cajon/San Diego 16.3 mi from Otay Mesa West 7.8/10 Good (1005) "Great place " £61 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/El-Cajon-Hotels-Super-8-By-Wyndham-El-Cajon-CA.h4926.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/4877ef6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/1194fa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/3a963240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/7bb755a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cordova Hotel on Coronado Island 10.2 mi from Otay Mesa West 8.8/10 Excellent (1008) "Perfect location! Close to beach, harbor and lots of dining options. Staff is very friendly and helpful. We stayed in the large suite which exceeded our expectations in every way." [](https://www.expedia.co.uk/Coronado-Hotels-El-Cordova-Hotel-On-Coronado-Island.h11395.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/aa7dcb3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/2639daee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/bb4bfc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20500/20454/a7e21110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus La Mesa San Diego 14.4 mi from Otay Mesa West 8.2/10 Very good (1011) "Had a great stay." £80 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/La-Mesa-Hotels-Best-Western-Plus-La-Mesa-San-Diego.h20454.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/54935ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View (1 Queen and 1 Sofabed) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/3de76bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/ddc5f050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/23c18b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gaslamp Plaza Suites Gaslamp Quarter, 11.3 mi from Otay Mesa West 9.0/10 Wonderful (1015) "Great stay and great for tourist " £91 includes taxes & fees 29 Sept - 30 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Gaslamp-Plaza-Suites.h16266.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/589f8e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 2 Double Beds, Roll-in Shower, City View | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/c0dfd2f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/75ec9582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel 11.5 mi from Otay Mesa West 8.4/10 Very good (1579) "I was very happy with my stay." £93 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Café](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/a3c5905c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/423e7241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort 6 mi from Otay Mesa West 8.8/10 Excellent (1036) "Loved this stay, will be back! " £220 includes taxes & fees 24 Sept - 25 Sept [](https://www.expedia.co.uk/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/2b01136a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/81f394e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/e71b90b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/325ce31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego-East/El Cajon 16.8 mi from Otay Mesa West 7.6/10 Good (1005) "Place was nice and comfy. Decent stay at a very genuine price. " £64 includes taxes & fees 2 Oct - 3 Oct [](https://www.expedia.co.uk/El-Cajon-Hotels-Days-Inn-By-Wyndham-San-Diego-EastEl-Cajon.h1175963.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Fab) | Premium bedding, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/febc9a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego 11.5 mi from Otay Mesa West 8.4/10 Very good (1380) "Great stay" [](https://www.expedia.co.uk/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Presidential Suite, 2 Bedrooms, Non Smoking | Living room | 36-inch LCD TV with digital channels, TV, pay films](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/daaed037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/b76d2e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Balcony, Bay View | Living room | 36-inch LCD TV with digital channels, TV, pay films](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/0ac5494a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | 1 bedroom, Frette Italian sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/aa3e65d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alma San Diego Downtown, a Tribute Portfolio Hotel 11.4 mi from Otay Mesa West 9.0/10 Wonderful (804) "Great stay!" £165 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-Alma-San-Diego-Downtown.h2133509.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/3b915004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking (Balcony) | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/139a6c49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/w4000h2664x0y0-982a04e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/88000000/87140000/87138000/87137975/0f34ec95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott San Diego Downtown Gaslamp Quarter Gaslamp Quarter, 11.2 mi from Otay Mesa West 8.8/10 Excellent (922) "Would definitely stay again!" £151 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/San-Diego-Hotels-AC-Hotel-By-Marriott-San-Diego-Downtown-Gaslamp-Quarter.h87137975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/fe340c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds, Non Smoking | Premium bedding, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/165a3a80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/0c67e9c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, Multiple Beds, Non Smoking | Premium bedding, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2220000/2217800/2217787/bd7d0518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Chula Vista/San Diego 4.5 mi from Otay Mesa West 6.2/10 (1012) "The staff was incredibly helpful" £62 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Chula-Vista-Hotels-Red-Roof-Inn-PLUS-Chula-Vista.h2217787.Hotel-Information) ![Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/89fdb8c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Gaslamp Quarter, 11 mi from Otay Mesa West 9.4/10 Exceptional (1009) "Very cute and comfortable stay" £140 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=553248625809641010&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Otay Mesa West Find the best Otay Mesa West areas for the activities you enjoy most. [Learn more about Otay Mesa West](https://www.expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010) - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAJjJtK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40mSei%40C_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=aolozqmF_PBFzbzgbobJQ3vpb28=) ### Downtown San Diego 2 out of top 10 points of interest in this area Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIBCk%5B%60x%40OmEpJ%7DPD%40zAiE%40A_ByEBDj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=xndIm_3yzAaEHMwouE9nfrTjoKg=) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, surfing and swimming](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes drinks or beverages and a beach bar](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBif%40inCqKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40vPgDfDlTbMbDlZu%40%60V%7EDxQfMtAjJg%40zH_GxEkRnGiUrA_Q%60IiF%60Tv%40nR%60J%7CNcKjBzCfUec%40%60LyUvImPbIuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ACgztVU9DQo8uAxGG0Fkzijg5pc=) ### Pacific Beach Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park showing a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%3FBd%40tDKhRoFnGs%40nEB%7COdBxF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=O82K2yNlOvRmPRFPBGu53Mr7cjo=) ### Mission Beach If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7D%40pnBb%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=idh6bbKgZQtLJECTXENLBA_2_Y0=) ### Ocean Beach Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=177689) ## Top Otay Mesa West Hotel Reviews ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Nice place .... convenient to airport and marines recruiting base." [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ![Paradise Point Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add_y.jpg) ### Paradise Point Resort & Spa 10/10 Excellent "Great experience " [](https://expedia.co.uk/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Conveniently located off the highway. Places to dine closeby. Love the room with amenities. Very welcoming staff. " [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-bc7b853b_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Clean Nice view Perfect location Expensive parking " [](https://expedia.co.uk/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Very nice and clean friendly staff " [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Sheraton San Diego Resort](//images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Great staff, nice room excellent bartender (Pablo or Paco, can’t remember) pool was great and the location doesn’t get any better. Born and raised in San Diego but the Sheraton sure made it feel like a vacation. Thank you. Parking was really expensive, I’ll be street parking in the future " [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Didn’t like I had to pay for parking but I did like the view " [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Love the unique vibe of this hotel. Amazing landscaping. The pool/hot tub area is fun to chill. They have fire pits and a nice restaurant with access to the pool. Rooms are very clean. " [](https://expedia.co.uk/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Excellent" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Otay Mesa West? > The [Best Western Chula Vista/Otay Valley Hotel](https://www.expedia.co.uk/Chula-Vista-Hotels-Best-Western-Chula-VistaOtay-Valley-Hotel.h12645.Hotel-Information) is an excellent choice for families seeking a comfortable and convenient stay. This hotel offers a refreshing pool area, superb for kids to splash around while parents relax nearby. The property also provides cribs at no extra charge, making it easy for families traveling with infants. Guests appreciate the daily housekeeping service that keeps everything tidy, along with microwaves in the rooms, ensuring you can prepare quick snacks for your little ones. > > > > Another family-friendly option is the [Motel 6 San Diego, CA - Southbay](https://www.expedia.co.uk/San-Diego-Hotels-Motel-6-San-Diego.h663151.Hotel-Information). This hotel is particularly accommodating for families with children, offering connecting rooms, which allow for easy supervision and bonding time. Young travellers can enjoy free stays, adding great value for families on a budget. Like the Best Western, this property also features housekeeping services and microwaves, making it convenient for families to settle in and feel at home. ### What hotels in Otay Mesa West offer free breakfast? > The [Best Western Chula Vista/Otay Valley Hotel](https://www.expedia.co.uk/Chula-Vista-Hotels-Best-Western-Chula-VistaOtay-Valley-Hotel.h12645.Hotel-Information) is a fantastic choice for travellers seeking comfort and convenience in Otay Mesa West. This hotel offers a delightful start to your day with a complimentary continental breakfast, ensuring you and your family can fuel up before heading out on your adventures. ### What are the best budget hotels in Otay Mesa West? > The [Best Western Chula Vista/Otay Valley Hotel](https://www.expedia.co.uk/Chula-Vista-Hotels-Best-Western-Chula-VistaOtay-Valley-Hotel.h12645.Hotel-Information) is a fantastic budget-friendly option in Otay Mesa West, offering families and travellers a comfortable stay with a variety of amenities. Guests appreciate the outdoor pool, great for splashing around after a day of exploration, and the complimentary continental breakfast ensures a great start to your day without breaking the bank. > > > > This hotel also caters to families, providing free cribs and accessible parking, making it easy for parents traveling with young children. The fitness centre allows adults to stay active, while free WiFi keeps everyone connected. With a customer review rating of 7.8, it's clear that many have found it to be a reliable choice for quality and convenience. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Otay Mesa West hotel for you. ### How can I save on a Otay Mesa West hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Otay Mesa West hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Otay Mesa West hotel? > Hotel prices in Otay Mesa West often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Atlantis Laser Tag](https://www.expedia.co.uk/Atlantis-Laser-Tag-Hotels.0-l553248621532638600-0.Travel-Guide-Filter-Hotels) - [Barrio Logan Hotels](https://www.expedia.co.uk/Barrio-Logan-San-Diego-Hotels.0-n553248635976388733-0.Travel-Guide-Filter-Hotels) - [Bonita Hotels](https://www.expedia.co.uk/Bonita-Hotels.d177687.Travel-Guide-Hotels) - [Hotels near Brown Field Municipal](https://www.expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Chula Vista Hotels](https://www.expedia.co.uk/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels) - [San Diego County Hotels](https://www.expedia.co.uk/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [Emerald Hills Hotels](https://www.expedia.co.uk/Emerald-Hills-San-Diego-Hotels.0-n797413919713509376-0.Travel-Guide-Filter-Hotels) - 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Explore a world of travel with Expedia ### Hotels in top San Diego neighborhoods - [Hotels in Downtown San Diego](https://expedia.co.uk/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Hotels in Gaslamp Quarter](https://expedia.co.uk/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Hotels in Pacific Beach](https://expedia.co.uk/Pacific-Beach-San-Diego-Hotels.0-n6185751-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Beach](https://expedia.co.uk/Mission-Beach-San-Diego-Hotels.0-n553248635998112279-0.Travel-Guide-Filter-Hotels) - [Hotels in Ocean Beach](https://expedia.co.uk/Ocean-Beach-San-Diego-Hotels.0-n177689-0.Travel-Guide-Filter-Hotels) - [Hotels in Point Loma](https://expedia.co.uk/Point-Loma-San-Diego-Hotels.0-n6171538-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Valley](https://expedia.co.uk/Mission-Valley-San-Diego-Hotels.0-n800124-0.Travel-Guide-Filter-Hotels) - [Hotels in Old Town San Diego](https://expedia.co.uk/Old-Town-San-Diego-San-Diego-Hotels.0-n6347116-0.Travel-Guide-Filter-Hotels) - 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[Hotels in University City](https://expedia.co.uk/University-City-San-Diego-Hotels.0-n553248635976008131-0.Travel-Guide-Filter-Hotels) - [Hotels in Torrey Pines](https://expedia.co.uk/Torrey-Pines-La-Jolla-Hotels.0-n553248632557170134-0.Travel-Guide-Filter-Hotels) - [Hotels in Marina District](https://expedia.co.uk/Marina-District-San-Diego-Hotels.0-n3000663388-0.Travel-Guide-Filter-Hotels) - [Hotels in Linda Vista](https://expedia.co.uk/Linda-Vista-San-Diego-Hotels.0-n553248635976388645-0.Travel-Guide-Filter-Hotels) ### Hotels near popular San Diego Attractions - [Hotels near San Diego Zoo](https://expedia.co.uk/San-Diego-Zoo-Hotels.0-l502547-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego Convention Center](https://expedia.co.uk/San-Diego-Convention-Center-Hotels.0-l6125294-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Bay](https://expedia.co.uk/Mission-Bay-Hotels.0-l6185904-0.Travel-Guide-Filter-Hotels) - [Hotels near San Ysidro Border Crossing](https://expedia.co.uk/San-Ysidro-Border-Crossing-Hotels.0-l553248621551385128-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Beach](https://expedia.co.uk/Mission-Beach-Hotels.0-l506109-0.Travel-Guide-Filter-Hotels) - [Hotels near Balboa Park](https://expedia.co.uk/Balboa-Park-Hotels.0-l507458-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego State University](https://expedia.co.uk/San-Diego-State-University-Hotels.0-l502542-0.Travel-Guide-Filter-Hotels) - [Hotels near Hotel Circle](https://expedia.co.uk/Hotel-Circle-Hotels.0-l6270979-0.Travel-Guide-Filter-Hotels) - [Hotels near Naval Base San Diego](https://expedia.co.uk/Naval-Base-San-Diego-Hotels.0-l553248635941372147-0.Travel-Guide-Filter-Hotels) - [Hotels near Port of San Diego](https://expedia.co.uk/Port-Of-San-Diego-Hotels.0-l6131855-0.Travel-Guide-Filter-Hotels) ### More accommodation types in Otay Mesa West - [Holiday Homes in San Diego](https://expedia.co.uk/San-Diego-Private-Holiday-Homes.d3073-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Apartments in San Diego](https://expedia.co.uk/San-Diego-Apartments.d3073-aaApartments.Travel-Guide-Accommodation) - [Cottages in San Diego](https://expedia.co.uk/San-Diego-Cottages.d3073-aaCottages.Travel-Guide-Accommodation) - [Villas in San Diego](https://expedia.co.uk/San-Diego-Villas.d3073-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in San Diego](https://expedia.co.uk/San-Diego-Guest-Houses.d3073-aaGuestHouses.Travel-Guide-Accommodation) - [Serviced Apartments in San Diego](https://expedia.co.uk/San-Diego-Apart-Hotels.d3073-aaApartHotels.Travel-Guide-Accommodation) - [Resorts in San Diego](https://expedia.co.uk/San-Diego-Hotel-Resorts.d3073-aaHotelResorts.Travel-Guide-Accommodation) - [Motels in San Diego](https://expedia.co.uk/San-Diego-Motels.d3073-aaMotels.Travel-Guide-Accommodation) - [Hostels in San Diego](https://expedia.co.uk/San-Diego-Hostels.d3073-aaHostels.Travel-Guide-Accommodation) - [Houseboats in San Diego](https://expedia.co.uk/San-Diego-Houseboats.d3073-aaHouseboats.Travel-Guide-Accommodation) - [Caravan Parks in San Diego](https://expedia.co.uk/San-Diego-Caravan-Parks.d3073-aaCaravanParks.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near San Diego Intl. Airport](https://expedia.co.uk/San-Diego-Intl-Airport-Hotels.0-aSAN-0.Travel-Guide-Filter-Hotels) - [Hotels near Brown Field Municipal Airport](https://expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field Airport](https://expedia.co.uk/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Hotels near McClellan-Palomar Airport](https://expedia.co.uk/McClellan-Palomar-Airport-Hotels.0-aCLD-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [San Diego Mission Bay Resort](https://expedia.co.uk/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) - [Best Western Plus Marina Gateway Hotel](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) - [Wyndham Garden San Diego Near SeaWorld](https://expedia.co.uk/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) - [Paradise Point Resort & Spa](https://expedia.co.uk/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) - [California Suites Hotel](https://expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) - [Days Inn by Wyndham San Diego Hotel Circle](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) - [Sheraton San Diego Resort](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) - [Best Western Inn & Suites San Diego – Zoo/SeaWorld Area](https://expedia.co.uk/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) - [Hilton San Diego Mission Valley](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) - [The Little Italy Hotel Downtown San Diego](https://expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) - [Loews Coronado Bay Resort](https://expedia.co.uk/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) - [Kings Inn San Diego](https://expedia.co.uk/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) [See a list of all hotels in San Diego](https://expedia.co.uk/All-San-Diego-Hotels.d3073.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Otay Mesa West on Expedia.com](https://www.expedia.com/Otay-Mesa-West-San-Diego-Hotels.0-n553248625809641010-0.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Echo Park Hotels](https://expedia.co.uk/Echo-Park-Los-Angeles-Hotels.0-n799568389158125568-0.Travel-Guide-Filter-Hotels) - [5 Star Montecito Accommodation](https://expedia.co.uk/5Star-Montecito-Santa-Barbara-Hotels.s50-n6055656-0.Travel-Guide-Filter-Hotels) - [Downtown San Diego Hotels](https://expedia.co.uk/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Gaslamp Quarter Hotels](https://expedia.co.uk/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Union Square Hotels](https://expedia.co.uk/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Hotels with Pool in Fisherman's Wharf](https://expedia.co.uk/Fishermans-Wharf-San-Francisco-Hotels-Hotels-With-Pool.0-n800128-0-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Downtown Los Angeles Hotels](https://expedia.co.uk/Downtown-Los-Angeles-Los-Angeles-Hotels.0-n800058-0.Travel-Guide-Filter-Hotels) - [Hollywood Hotels](https://expedia.co.uk/Hollywood-Los-Angeles-Hotels.0-n8365-0.Travel-Guide-Filter-Hotels) - [Russian Hill Hotels](https://expedia.co.uk/Russian-Hill-San-Francisco-Hotels.0-n553248621561137041-0.Travel-Guide-Filter-Hotels) - [Castro District Hotels](https://expedia.co.uk/Castro-District-San-Francisco-Hotels.0-n179363-0.Travel-Guide-Filter-Hotels) - [5 Star Hollywood Accommodation](https://expedia.co.uk/5Star-Hollywood-Los-Angeles-Hotels.s50-n8365-0.Travel-Guide-Filter-Hotels) - [Fisherman's Wharf Hotels](https://expedia.co.uk/Fishermans-Wharf-San-Francisco-Hotels.0-n800128-0.Travel-Guide-Filter-Hotels) Cars - [Car hire in Downtown Los Angeles](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-Los-Angeles.d800058.Car-Hire-Guide) - [Car hire in Downtown San Francisco](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-San-Francisco.d6151902.Car-Hire-Guide) - [Car hire in Fisherman's Wharf](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Fishermans-Wharf.d800128.Car-Hire-Guide) - [Car hire in Union Square](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Union-Square.d800129.Car-Hire-Guide) Packages - [Downtown Los Angeles Holidays](https://expedia.co.uk/Downtown-Los-Angeles.d800058.Holidays-City-Breaks) - [Hollywood Holidays](https://expedia.co.uk/Hollywood.d8365.Holidays-City-Breaks) General - [Visit Fisherman's Wharf](https://expedia.co.uk/San-Francisco-Fishermans-Wharf.dx800128) - [Visit Hollywood Hills](https://expedia.co.uk/Los-Angeles-Hollywood-Hills.dx553248635074843803) - [Visit Downtown Los Angeles](https://expedia.co.uk/Los-Angeles-Downtown-Los-Angeles.dx800058) - [Visit Union Square](https://expedia.co.uk/San-Francisco-Union-Square.dx800129) - [Visit Skid Row](https://expedia.co.uk/Los-Angeles-Skid-Row.dx553248635976007248) - [Visit Silver Lake](https://expedia.co.uk/Los-Angeles-Silver-Lake.dx3000663210) - [Visit Nob Hill](https://expedia.co.uk/San-Francisco-Nob-Hill.dx138629) - [Visit Ocean Beach](https://expedia.co.uk/San-Diego-Ocean-Beach.dx177689) - [Visit Hollywood](https://expedia.co.uk/Los-Angeles-Hollywood.dx8365) - [Visit Downtown San Diego](https://expedia.co.uk/San-Diego-Downtown-San-Diego.dx800123) - [Visit Newbury Park](https://expedia.co.uk/Los-Angeles-Newbury-Park.dx602883) - [Visit Downtown San Francisco](https://expedia.co.uk/San-Francisco-Downtown-San-Francisco.dx6151902)