Title: The Best Hotels in Otay Mesa West, San Diego - 2026 Updated Prices | Expedia.co.uk [Otay Mesa West Travel Guide](https://expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010)[Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Otay Mesa West Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Otay-Mesa-West.d553248625809641010.Car-Hire-Guide)[Otay Mesa West Holidays](https://expedia.co.uk/Otay-Mesa-West.d553248625809641010.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Otay Mesa West, San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248625809641010&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Otay Mesa West hotels ![Reception](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, desk, laptop workspace](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2557x3y3-1277fb5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2560x3y0-23cd0701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/w3837h2557x3y3-af97ac41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites by Hilton San Diego SeaWorld [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) 15.1 mi from Otay Mesa West 9.2/10 Wonderful (413) "Clean rooms, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KARLA £87 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/33000000/32750000/32749300/32749216/1e452245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32750000/32749300/32749216/ce92baf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/33000000/32750000/32749300/32749216/0bb53c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/33000000/32750000/32749300/32749216/208830f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites San Diego Airport Liberty Station [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Airport-Liberty-Station.h32749216.Hotel-Information) 13.9 mi from Otay Mesa West 9.2/10 Wonderful (1701) "Excellent place " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Rafael £131 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Airport-Liberty-Station.h32749216.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/f5805846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Living room | 55-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/7182df27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/c69001c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Downtown Little Italy [](https://www.expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) Little Italy, 11.9 mi from Otay Mesa West 9.0/10 Wonderful (109) "It was a nice place to stay at" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £102 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/69000000/68340000/68333500/68333402/709ba2dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68340000/68333500/68333402/d4c01c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/69000000/68340000/68333500/68333402/135c5dc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/69000000/68340000/68333500/68333402/6f235371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott San Diego Pacific Beach [](https://www.expedia.co.uk/San-Diego-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Diego-Mission-Bay.h68333402.Hotel-Information) Pacific Beach, 18.1 mi from Otay Mesa West 9.0/10 Wonderful (803) "good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sisi £88 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Fairfield-Inn-Suites-By-Marriott-San-Diego-Mission-Bay.h68333402.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/12000000/11990000/11981200/11981154/39135f25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Kitchen | Private kitchen | Fridge, microwave, coffee/tea maker, paper towels](https://images.trvl-media.com/lodging/12000000/11990000/11981200/11981154/7d087732.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Kitchen | Hypo-allergenic bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/12000000/11990000/11981200/11981154/d7e34a22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/12000000/11990000/11981200/11981154/e8b14ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at Sunset Cliffs [](https://www.expedia.co.uk/San-Diego-Hotels-The-Inn-At-Sunset-Cliffs.h11981154.Hotel-Information) Ocean Beach, 16 mi from Otay Mesa West 9.2/10 Wonderful (1001) "Great place beautiful view " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josue £165 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-The-Inn-At-Sunset-Cliffs.h11981154.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/68b54340.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/02dbf386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/e70fb26b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/21600/21527/c7295677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Yacht Harbor Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Best-Western-Yacht-Harbor-Hotel.h21527.Hotel-Information) 14.2 mi from Otay Mesa West 8.6/10 Excellent (1634) "The breakfast options were good and the staff were very helpful." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Gail or Rob £86 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Best-Western-Yacht-Harbor-Hotel.h21527.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/80f275da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/30420c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/ecc06b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/60000/57300/57254/42d1a51f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Harbor Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Sea-Harbor-Hotel.h57254.Hotel-Information) 14.3 mi from Otay Mesa West 8.6/10 Excellent (1005) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Naomi £79 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Sea-Harbor-Hotel.h57254.Hotel-Information) ![Standard Room, 2 Queen Beds | Pillow-top beds, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/ee1bc66b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/bbccca79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/9325a8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/430000/428500/428450/f928b115.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### GreenTree Inn San Diego Mission Bay [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Sea-World-Beach-Area.h428450.Hotel-Information) Pacific Beach, 18.2 mi from Otay Mesa West 8.0/10 Very good (1869) "Courteous staff and clean room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel £76 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Sea-World-Beach-Area.h428450.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/c05932db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/c20297ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/87139cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking (Mobility,Roll-In Shower) | Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/11400/11366/6b45c622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Diego Mission Bay [](https://www.expedia.co.uk/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) North Pacific Beach, 18.5 mi from Otay Mesa West 8.0/10 Very good (1431) "Friendly staff, clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice £78 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Diego-Mission-Bay.h11366.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/ddcd0247.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/w3839h2549x0y5-2be78d7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/291cfcc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/10000/8700/8604/aeccf49c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego-Kearny Mesa [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Kearny-Mesa.h8604.Hotel-Information) 18.4 mi from Otay Mesa West 9.0/10 Wonderful (1014) "It was a very nice stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas £87 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Kearny-Mesa.h8604.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/37cb1415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/1f20ac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/5619e933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bay Club Hotel & Marina [](https://www.expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) 13.7 mi from Otay Mesa West 9.2/10 Wonderful (3189) "Great stay and location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £100 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5597/116c96a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/5600/5597/580f5561.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/5600/5597/595e21dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5600/5597/d04df095.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Bayside Inn [](https://www.expedia.co.uk/San-Diego-Hotels-Best-Western-Plus-Bayside-Inn.h5597.Hotel-Information) 11.8 mi from Otay Mesa West 9.0/10 Wonderful (1002) "Great staff and location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £110 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Best-Western-Plus-Bayside-Inn.h5597.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/2000000/1050000/1048200/1048111/f99bf9f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1050000/1048200/1048111/4b4ac885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/2000000/1050000/1048200/1048111/1f64b647.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/2000000/1050000/1048200/1048111/8c3ba740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Beach Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Ocean-Beach-Hotel.h1048111.Hotel-Information) Ocean Beach, 16.5 mi from Otay Mesa West 8.8/10 Excellent (1273) "Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maryna [](https://www.expedia.co.uk/San-Diego-Hotels-Ocean-Beach-Hotel.h1048111.Hotel-Information) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/590000/581100/581034/075bf15f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/590000/581100/581034/0f976e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/590000/581100/581034/9b2b3d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/590000/581100/581034/a770253c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western San Diego Pacific Beach [](https://www.expedia.co.uk/San-Diego-Hotels-SureStay-Hotel-By-Best-Western-San-Diego-Pacific-Beach.h581034.Hotel-Information) Pacific Beach, 18.3 mi from Otay Mesa West 8.0/10 Very good (1416) "our stay was great and staff was supportive..." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramesh £67 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-SureStay-Hotel-By-Best-Western-San-Diego-Pacific-Beach.h581034.Hotel-Information) ![Theatre show](https://images.trvl-media.com/lodging/2000000/1700000/1692000/1691980/6a458e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1700000/1692000/1691980/5e2ca837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1700000/1692000/1691980/8e2d0fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Boating](https://images.trvl-media.com/lodging/2000000/1700000/1692000/1691980/c5d30bf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton San Diego Airport/Liberty Station [](https://www.expedia.co.uk/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-AirportLiberty-Station.h1691980.Hotel-Information) 14.1 mi from Otay Mesa West 9.4/10 Exceptional (1350) "Great place to stay at!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandy £136 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-AirportLiberty-Station.h1691980.Hotel-Information) ![2 outdoor pools, a heated pool, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/01ecd568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/f03b817a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/444d7583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dana on Mission Bay [](https://www.expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) Mission Bay, 16.8 mi from Otay Mesa West 9.0/10 Wonderful (3931) "Always love staying here. Staff was very courteous and the rooms very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £134 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/a98dc1ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/4ea64dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/b67130be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202716/90271416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn San Diego [](https://www.expedia.co.uk/San-Diego-Hotels-Heritage-Inn-San-Diego-Near-SeaWorld.h2202716.Hotel-Information) 15.6 mi from Otay Mesa West 7.4/10 Good (1165) "Clean room, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin £47 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Heritage-Inn-San-Diego-Near-SeaWorld.h2202716.Hotel-Information) ![Beach nearby, scuba diving](https://images.trvl-media.com/lodging/1000000/20000/17300/17223/3466f59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17300/17223/1c0c983d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/17300/17223/fb074890.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17300/17223/d54ae0a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### PB Surf Beachside Inn [](https://www.expedia.co.uk/San-Diego-Hotels-PB-Surf-Beachside-Inn.h17223.Hotel-Information) North Pacific Beach, 19.4 mi from Otay Mesa West 8.2/10 Very good (1000) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ernest £77 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-PB-Surf-Beachside-Inn.h17223.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10640000/10637400/10637315/750cafaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Motel Room, 1 Queen Bed, West Wing, Partial Ocean View | Balcony view](https://images.trvl-media.com/lodging/11000000/10640000/10637400/10637315/aad0e2b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10640000/10637400/10637315/4ce53da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 2 Bedrooms, 2 Bathrooms, Ground Floor | Terrace/patio](https://images.trvl-media.com/lodging/11000000/10640000/10637400/10637315/38715e43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Beach Cottages [](https://www.expedia.co.uk/San-Diego-Hotels-The-Beach-Cottages.h10637315.Hotel-Information) Pacific Beach, 18.9 mi from Otay Mesa West 9.2/10 Wonderful (1002) "Staff was very helpful, place was clean, fun with all the Xmas bars and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gay Marie £94 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-The-Beach-Cottages.h10637315.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/f3168007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a9bcd444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter [](https://www.expedia.co.uk/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) Gaslamp Quarter, 11 mi from Otay Mesa West 9.0/10 Wonderful (1228) "Nice Residence Inn" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry £119 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=553248625809641010&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Otay Mesa West Find the best Otay Mesa West areas for the activities you enjoy most. [Learn more about Otay Mesa West](https://www.expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010) - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, surfing and swimming](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes drinks or beverages and a beach bar](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park showing a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=177689) ## Top Otay Mesa West Hotel Reviews ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Exactly as described " [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Overall- the staff, property and room were great " [](https://expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "My favorite hotel in San Diego. Staff is always helpful, kind and professional. The rooms are comfortable, clean, eclectic and possibly the best minibar selection of top shelf products anywhere. The property invites you to discover and play and socialize. The bar and food programs are superb. " [](https://expedia.co.uk/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Manchester Grand Hyatt San Diego](https://images.trvl-media.com/lodging/1000000/20000/12100/12073/91e2517e_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "When I asked about breakfast they said I didn’t have it" [](https://expedia.co.uk/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "Nice room and beds" [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Great hotel! Enjoyed our rooms and the staff was very accommodating to our party with two small children." [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean. Great room " [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "great spot to catch a cruise. awesome view of the bay" [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Clean room staff gently " [](https://expedia.co.uk/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ## Frequently asked questions ### What are the best family hotels in Otay Mesa West? > Another family-friendly option is the [Motel 6 San Diego, CA - Southbay](https://www.expedia.co.uk/San-Diego-Hotels-Motel-6-San-Diego.h663151.Hotel-Information). This hotel is particularly accommodating for families with children, offering connecting rooms, which allow for easy supervision and bonding time. Young travellers can enjoy free stays, adding great value for families on a budget. Like the Best Western, this property also features housekeeping services and microwaves, making it convenient for families to settle in and feel at home. ### What hotels in Otay Mesa West offer free breakfast? ### What are the best budget hotels in Otay Mesa West? > This hotel also caters to families, providing free cribs and accessible parking, making it easy for parents traveling with young children. The fitness centre allows adults to stay active, while free WiFi keeps everyone connected. With a customer review rating of 7.8, it's clear that many have found it to be a reliable choice for quality and convenience. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Otay Mesa West hotel booking with Expedia? ### How much is the nightly rate at a Otay Mesa West hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Atlantis Laser Tag ](https://www.expedia.co.uk/Atlantis-Laser-Tag-Hotels.0-l553248621532638600-0.Travel-Guide-Filter-Hotels) - [Barrio Logan Hotels ](https://www.expedia.co.uk/Barrio-Logan-San-Diego-Hotels.0-n553248635976388733-0.Travel-Guide-Filter-Hotels) - [Bonita Hotels ](https://www.expedia.co.uk/Bonita-Hotels.d177687.Travel-Guide-Hotels) - [Hotels near Brown Field Municipal ](https://www.expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Chula Vista Hotels ](https://www.expedia.co.uk/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels) - 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