Otay Mesa West Holidays from £979

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Your Otay Mesa West Holiday

Otay Mesa West is calling! Whatever type of getaway you're organising, you can see and experience the best of this neighbourhood with an Otay Mesa West holiday package. If you're all about sightseeing, no trip to Otay Mesa West is complete without stopping by nearby Kaiser Permanente Otay Mesa Medical Offices. Expedia is here to put your travel plans into action. Book your ultimate Otay Mesa West holiday now.

Price found within the past 48 hours. Click for updated prices.
Ash&9th

Ash&9th

2 out of 5
Downtown San Diego
Price was £1,169, price is now £979 per person
£979
per person
12 Sept - 19 Sept
found 15 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
8.2/10 Very good! (826 reviews)
Good experience. Guy at the front counter was very nice & helpful. Property was close to everything. Great stay. When back in San Diego I would come back the this hotel to stay

Reviewed on 31 Jul 2026

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was £1,450, price is now £1,111 per person
£1,111
per person
21 Sept - 24 Sept
found 1 day ago
Return flight included
London (LON) to San Diego (SAN)
8.6/10 Excellent! (2,403 reviews)

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

2.5 out of 5
Hillcrest
Price was £1,154, price is now £1,028 per person
£1,028
per person
12 Sept - 19 Sept
found 15 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
8.4/10 Very good! (414 reviews)
Really nice, great ac, parking garage is small but made room for us along the wall. Only problem I had was the ants consistently on the counter, and both of the towels having hair on them.

Reviewed on 30 Jul 2026

InterContinental San Diego by IHG

InterContinental San Diego by IHG

4 out of 5
Downtown San Diego
Price was £1,695, price is now £1,515 per person
£1,515
per person
21 Sept - 24 Sept
found 1 day ago
Return flight included
London (LON) to San Diego (SAN)
9.2/10 Wonderful! (1,178 reviews)
I never received my bill and I was charged one extra night because the staff thought I never checked out in time even though I left the premises in the morning. I was told on the phone by the person at the front desk that everything was taken care of but I was still charged the extra night.

Reviewed on 31 Jul 2026

Ramada by Wyndham San Diego Airport

Ramada by Wyndham San Diego Airport

3 out of 5
Point Loma
Price was £1,193, price is now £1,074 per person
£1,074
per person
12 Sept - 19 Sept
found 15 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
7.6/10 Good! (1,010 reviews)
My car was broke into management did not care security sucks rooms smell moldy ac didn't work well won't stay there again nor would I recommend it to anyone very disappointed in the management and the lack of care called and asked for a copy of the footage and couldn't even get a call back

Reviewed on 31 Jul 2026

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
A grand building with a central fountain, palm trees, and a flag.

Downtown San Diego

4 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Otay Mesa West

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is £243 per night from 30 Aug to 31 Aug
£243
30 Aug - 31 Aug
includes taxes & fees
8.8/10 Excellent! (2,762 reviews)
"everything we needed was right there on property."

Reviewed on 1 Aug 2026

Paradise Point Resort & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
The price is £164 per night from 2 Aug to 3 Aug
£164
2 Aug - 3 Aug
includes taxes & fees
Wyndham San Diego Bayside
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4 out of 5
1500 Orange Ave Coronado CA
Fully refundableReserve now, pay when you stay
The price is £493 per night from 23 Aug to 24 Aug
£493
23 Aug - 24 Aug
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
"Tens of thousands of gallons of untreated sewage. The beach and all adjacent beaches were too polluted with feces and unsafe to even touch the water. The beach advisories warned to not touch the water due to contamination. The water was brown. This evil hotel did not warn you ahead of time, nor when ..."

Reviewed on 31 Jul 2026

Hotel del Coronado, Curio Collection by Hilton
See all 7,004 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Family Friendly Holidays

Frequently asked questions

How much does an Otay Mesa West travel package cost?
Get set to book, because a trip to Otay Mesa West starts from an affordable £979. When you bundle your flights, hotels and more into a travel package, you'll score the best prices.
If I'm not able to travel, can I cancel my Otay Mesa West travel package?
Whether it's your hotel or flight, you can cancel or change it. Locked in your Otay Mesa West travel package in the last 24 hours? You may be able to make changes or cancellations at no cost. For older bookings, you may incur a charge from your hotel, airline or car rental company. For more details, take a look at our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Otay Mesa West?
Combining your hotel and flight with Expedia won't just save precious time — it'll save you cash too. An Otay Mesa West travel package makes it easy to organise your perfect trip. With more than 550 airlines throughout the world to select from, finding convenient flights that suit your busy schedule won't be hard. On top of that, we've got over 1,000,000 hotels globally to pick from. Talk about choice! Whatever your budget, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Otay Mesa West holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has devised a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a dream getaway without hurting your hip pocket. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month is something that would work for you, Klarna offers just that! Paying in easy monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Consider this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: Clicking the "book now" button is much easier with this plan. Put down a small deposit on your booking and then start packing your suitcase.

Where should I stay in Otay Mesa West?
A visit to Otay Mesa West isn't complete without stopping by SeaWorld and San Diego Zoo. Look for somewhere to stay as close as possible for easy access to these fantastic tourist attractions.
What are the top hotels in Otay Mesa West?
Book a stay at Manchester Grand Hyatt San Diego. It's one of this neighbourhood's most in-demand properties. Another reputable option in Otay Mesa West is Paradise Point Resort And Spa.
How far in advance should I book my Otay Mesa West holiday?
While prices change frequently, we generally suggest booking your spot as early as possible. Many international fares can be compared on Expedia up to 12 months in advance. If you're booking last minute, you may still get lucky. Cheap tickets to Otay Mesa West sometimes occur just weeks before departure.
What does an Expedia Otay Mesa West travel package include?
Rental cars, flights and hotels — we have them well covered. With Expedia, you can create your Otay Mesa West travel package however you want. All you have to do is work out exactly what you need. Once you've made your booking, you can add on fun things like experiences and activities. The more you bundle, the greater the savings!
What should I know before booking an Otay Mesa West travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a tidy sum. Whatever your holiday plans, you're sure to find a package that's perfect for you.
Can I choose my airline with an Otay Mesa West Expedia travel package?
Yes, and with over 550 airlines to pick from around the world, you've got lots of choice. Look through the available options and see which airline fits your needs and budget.

Things to do

LEGOLAND® California Resort

LEGOLAND® California Tickets

£68
per adult
84% of travellers recommend
LEGOLAND® California Tickets
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

£54
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

£8
per adult
80% of travellers recommend
San Diego: Luggage Storage in Marina
See all activities in San Diego

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.