Title: Full-size Greenville - Spartanburg Car Hire | Expedia.co.uk ![](https://images.trvl-media.com/place/6035267/171062aa-83ef-40ef-8525-0e78a0f82378.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Full-size Car Hire Companies in Greenville - Spartanburg Photo by Visit Greenville, South Carolina - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Find Cheap Full-size Car Deals for Greenville - Spartanburg \* Price found within the past 6 days. Click for updated prices. Sun, 30 Nov - Mon, 1 Dec ### Fullsize 2/4 Door Car Toyota Camry or similar or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 1960 Gsp Drive Greenville Spartanburg Apo, Greenville, South Carolina 29651, USA 9.51 mi from Greenville - Spartanburg city centre ![Toyota Camry or similar](https://mediaim.expedia.com/cars/41/f8359e2f-1f3f-4c65-ac4c-bc85e53c01f5.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £43 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=34.89&olon=-82.217222&totalprice=43.40¤cy=GBP&date1=30/11/2025&date2=01/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=43.40&cvrfrr=ZI&ctrfrr=FC&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvokk3Xbovh4dhc8VrL3KQTnpSGHLieRZyHPTEWifCQ4JI8UQ6uGWQYRCb4o6jGwn2Ic&selCC=[%22fullsize%22]) Sun, 30 Nov - Mon, 1 Dec ### Fullsize 4/5 Door Car Ford Fusion, Nissan Altima, Toyota Camry or similar or similar - 5 people - Unlimited mileage ![Enterprise](//mediaim.expedia.com/cars/logos/ET.png) #### Pick-up location 500 Aviation Pkwy Ste 15, Greenville, South Carolina, USA 9.52 mi from Greenville - Spartanburg city centre ![Ford Fusion, Nissan Altima, Toyota Camry or similar](https://mediaim.expedia.com/cars/15/7fcf6520-9757-49b3-891a-ba97a9b969c9.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £73 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=34.884293&olon=-82.215779&totalprice=72.51¤cy=GBP&date1=30/11/2025&date2=01/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=72.51&cvrfrr=ET&ctrfrr=FD&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvokLpcDzrTDsV81QyIb8CHYD-y9DJGAyDxbz1oTeKgKKxAjMh61tOvCLiVlYMsIiiLc&selCC=[%22fullsize%22]) Sun, 30 Nov - Mon, 1 Dec ### Fullsize 4/5 Door Car Ford Fusion, Nissan Altima, Toyota Camry or similar or similar - 5 people - Unlimited mileage ![National Car Rental](//mediaim.expedia.com/cars/logos/ZL.png) #### Pick-up location 500 Aviation Parkway Suite 24, Greer, South Carolina 29651, USA 9.18 mi from Greenville - Spartanburg city centre ![Ford Fusion, Nissan Altima, Toyota Camry or similar](https://mediaim.expedia.com/cars/42/4291e61c-308d-49c6-8bfc-c006281c5b26.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £73 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=34.8775&olon=-82.2206&totalprice=73.28¤cy=GBP&date1=30/11/2025&date2=01/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=73.28&cvrfrr=ZL&ctrfrr=FD&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvonJgd-kv4r8xL_RNKCxXq2tCd_gCqAKiAbZLG8pmGDCHMUQ6uGWQYRCb4o6jGwn2Ic&selCC=[%22fullsize%22]) Sun, 30 Nov - Mon, 1 Dec ### Fullsize SUV GMC Yukon Denali or similar or similar - 7 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 1960 Gsp Drive Greenville Spartanburg Apo, Greenville, South Carolina 29651, USA 9.51 mi from Greenville - Spartanburg city centre ![GMC Yukon Denali or similar](https://mediaim.expedia.com/cars/41/73fd7fdb-25c4-48fd-acd8-6b7404681cac.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £90 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=34.89&olon=-82.217222&totalprice=90.40¤cy=GBP&date1=30/11/2025&date2=01/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=90.40&cvrfrr=ZI&ctrfrr=FF&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvokk3Xbovh4dhc8VrL3KQTnpD6FekAvRtoyfYNk1mFkGWsUQ6uGWQYRCb4o6jGwn2Ic&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Greenville - Spartanburg [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Greenville%20-%20Spartanburg,%20South%20Carolina,%20United%20States%20of%20America&dpln=6035267&date1=06/12/2025&date2=08/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22fullsize%22]) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_BF_PROMO_6035267) ## Fullsize Car Hire Information | Car type: | Fullsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in Greenville](https://www.expedia.co.uk/4Star-Greenville-Hotels.s40-0-d1388.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Greenville](https://www.expedia.co.uk/5Star-Greenville-Hotels.s50-0-d1388.Travel-Guide-Filter-Hotels) - [Colonel Elias Earle Historic District Hotels](https://www.expedia.co.uk/Colonel-Elias-Earle-Historic-District-Greenville-Hotels.0-n6348165-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Green Avenue](https://www.expedia.co.uk/Green-Avenue-Greenville-Hotels-Gay-Friendly-Hotel.0-n553248635976476062-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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[Welcome Hotels](https://www.expedia.co.uk/Welcome-Hotels.d553248634999220752.Travel-Guide-Hotels) - [West End Hotels](https://www.expedia.co.uk/West-End-Greenville-Hotels.0-n6348163-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Woodside Cotton Mill Village Historic District](https://www.expedia.co.uk/Woodside-Cotton-Mill-Village-Historic-District-Greenville-Hotels-Gay-Friendly-Hotel.0-n6348166-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Woodside Cotton Mill Village Historic District](https://www.expedia.co.uk/Woodside-Cotton-Mill-Village-Historic-District-Greenville-Hotels-Marriott-Hotels-Resorts.0-n6348166-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Woodside Cotton Mill Village Historic District Hotels](https://www.expedia.co.uk/Woodside-Cotton-Mill-Village-Historic-District-Greenville-Hotels.0-n6348166-0.Travel-Guide-Filter-Hotels) - [Flights to Greenville](https://www.expedia.co.uk/Cheap-Flights-To-Greenville.d1388.Travel-Guide-Flights) - [Flights from Greenville Downtown](https://www.expedia.co.uk/lp/airports/gmu/flights-from-greenville-downtown-airport) - [Flights from Greenville](https://www.expedia.co.uk/lp/flights/1388/flights-from-greenville) - [Flights from Dunean](https://www.expedia.co.uk/lp/flights/553248634999354841/flights-from-dunean) - [Flights from Augusta (AGS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ags/gmu/augusta-to-greenville) - [Flights from Anderson (AND) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/and/gmu/anderson-to-greenville) - [Flights from Atlanta (ATL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/atl/gmu/atlanta-to-greenville) - [Flights from Detroit (DTW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/dtw/gmu/detroit-to-greenville) - [Flights from Newark Liberty Intl. Airport (EWR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/ewr/gmu/newark-liberty-intl-airport-to-greenville) - [Flights from Gaithersburg (GAI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/gai/gmu/gaithersburg-to-greenville) - [Flights from Greenwood (GRD) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/grd/gmu/greenwood-to-greenville) - [Flights from Hagerstown (HGR) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/hgr/gmu/hagerstown-to-greenville) - [Flights from Islip (ISP) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/isp/gmu/islip-to-greenville) - [Flights from Jacksonville (JAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/jax/gmu/jacksonville-to-greenville) - [Flights from Las Vegas (LAS) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/las/gmu/las-vegas-to-greenville) - [Flights from Los Angeles (LAX) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/lax/gmu/los-angeles-to-greenville) - [Flights from Morgantown (MGW) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgw/gmu/morgantown-to-greenville) - [Flights from Dayton (MGY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/mgy/gmu/dayton-to-greenville) - [Flights from New Orleans (MSY) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/msy/gmu/new-orleans-to-greenville) - [Flights from Rocky Mount (RWI) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/rwi/gmu/rocky-mount-to-greenville) - [Flights from Louisville (SDF) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/sdf/gmu/louisville-to-greenville) - [Flights from St. Louis (STL) to Greenville (GMU)](https://www.expedia.co.uk/lp/flights/stl/gmu/st-louis-to-greenville) - [Bi Lo Center](https://www.expedia.co.uk/Bi-Lo-Center-Greenville-Downtown.d553248621558035357.Attraction) - [Visit Woodside Cotton Mill Village Historic District](https://www.expedia.co.uk/Greenville-Woodside-Cotton-Mill-Village-Historic-District.dx6348166) - [Greenville Holidays](https://www.expedia.co.uk/Greenville.d1388.Holidays-City-Breaks) - [Visit Greenville](https://www.expedia.co.uk/Greenville.dx1388) - [Patewood Memorial Hospital](https://www.expedia.co.uk/Patewood-Memorial-Hospital-Greenville.d6130783.Attraction) - [Wade Hampton Mall Shopping Center](https://www.expedia.co.uk/Wade-Hampton-Mall-Shopping-Center-Greenville.d553248621563220423.Attraction) - [Warehouse Theatre](https://www.expedia.co.uk/Warehouse-Theatre-Greenville-Downtown.d553248621532656721.Attraction) - [Alamo Rent A Car Rental Cars in Greenville](https://www.expedia.co.uk/Alamo-Rent-A-Car-Car-Rentals-In-Greenville.d1388-c6.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Greenville](https://www.expedia.co.uk/Avis-Car-Rentals-In-Greenville.d1388-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Greenville](https://www.expedia.co.uk/Budget-Car-Rentals-In-Greenville.d1388-c39.Car-Rental-Guide-Suppliers) - [Car hire Greenville](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville.d1388.Car-Hire-Guide) - [Convertible Car Hire in South Carolina](https://www.expedia.co.uk/Convertible-Car-Rentals-In-South-Carolina.d242-tConvertible.Car-Rental-Destination-Class) - 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