Title: Top Hotels in Scott County - Compare Scott County Hotels | Expedia.co.uk [Holiday Rentals in Scott County](https://expedia.co.uk/Destinations-In-Scott-County.d553248635976434022.Holiday-Rental-Destinations)[Scott County Car Hire](https://expedia.co.uk/Destinations-In-Scott-County.d553248635976434022.Car-Hire-Destinations)[Scott County Holidays](https://expedia.co.uk/Scott-County.d553248635976434022.Holidays-City-Breaks) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Abbie Moon # Find the best Scott County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Scott County Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/798fcf2b70d51325aa2ef18edc87befc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Sikeston [](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) ## Check prices for these dates Tonight [30 Dec - 31 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976434022&startDate=2025-12-30&endDate=2025-12-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [31 Dec - 1 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976434022&startDate=2025-12-31&endDate=2026-01-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976434022&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976434022&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Scott County hotels ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1003) "This our favorite place to stop for a good night sleep. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eileen £77 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (455) "Very clean and super friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katherine £86 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1005) "Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £53 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) Sikeston 9.4/10 Exceptional (1007) "Very clean, very friendly! We will be staying again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth £64 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very good (1005) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £67 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very good (725) "Clean room and easy access to room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne £47 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.2/10 Wonderful (43) "THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AHMAD £88 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout curtains, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.6/10 (615) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana £51 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (444) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney £78 includes taxes & fees 25 Jan - 26 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) Sikeston 6.8/10 (569) "Excellent check-in process! Extremely friendly staff. Room is very adequate. Everything you need. Price was a great bargain." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronald £50 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/917691e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.0/10 Wonderful (10) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott £106 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cde4423c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Charleston - Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) Charleston 6.8/10 (407) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/664c9838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5be64f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) Sikeston 8.4/10 Very good (283) "The hotel was very clean, beds were comfortable, and staff was friendly and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) aileen £75 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/131ce4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.co.uk/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (121) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £47 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/e769dedb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/2b61a8ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Charleston 6.6/10 (105) "Middle of nowhere hotel was ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £50 includes taxes & fees 31 Dec - 1 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/1c6c31ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/824c377e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/d39634e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/104000000/103900000/103892700/103892640/450d2061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Building at Cape Girardeau Regional Airport [](https://www.expedia.co.uk/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) Scott City £463 includes taxes & fees 31 Dec - 1 Jan 2026 [](https://www.expedia.co.uk/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/c7fd89d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/aab8c593.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/ee2b7138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, blender](https://images.trvl-media.com/lodging/77000000/76030000/76020500/76020481/6045fc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern and Cozy Apartment with large windows and sunlight. [](https://www.expedia.co.uk/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) Sikeston [](https://www.expedia.co.uk/Sikeston-Hotels-Modern-And-Cozy-Apartment-With-Large-Windows-And-Sunlight.h76020481.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (1011) "This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £75 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (479) "The room was clean and the mattress was extremely comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacy £73 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 8.8/10 Excellent (679) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GUY £72 includes taxes & fees 15 Jan - 16 Jan 2026 [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-13&endDate=2026-01-14®ionId=553248635976434022&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Scott-County.d553248635976434022.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Scott-County.d553248635976434022.Hotel-Destinations) ## Top Scott County Hotel Reviews ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Always a pleasant stay. Friendly staff, clean rooms, accessible pool and great food." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Clean and very nice room " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Great stay" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays." [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "clean room, comfy bedding, nice staff, convenient location " [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Affordable and confortable" [](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "This our favorite place to stop for a good night sleep. " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Great location! Great staff well above and beyond. Will definitely stay again." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Breakfast great hot and big variety " [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Scott County - [Miner Hotels ](https://expedia.co.uk/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Scott City Hotels ](https://expedia.co.uk/Scott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) - [Benton Hotels ](https://expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Oran Hotels ](https://expedia.co.uk/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Morley Hotels ](https://expedia.co.uk/Morley-Hotels.d553248634983172137.Travel-Guide-Hotels) - [Kelso Hotels ](https://expedia.co.uk/Kelso-Hotels.d553248634983171130.Travel-Guide-Hotels) - [Blodgett Hotels ](https://expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Vanduser Hotels ](https://expedia.co.uk/Vanduser-Hotels.d553248634983298513.Travel-Guide-Hotels) - [Commerce Hotels ](https://expedia.co.uk/Commerce-Hotels.d553248634983177483.Travel-Guide-Hotels) - [Diehlstadt Hotels ](https://expedia.co.uk/Diehlstadt-Hotels.d553248634983544913.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Mississippi River ](https://expedia.co.uk/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Shawnee National Forest ](https://expedia.co.uk/Shawnee-National-Forest-Hotels.0-l553248635944113522-0.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University ](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Hotels near Ohio River Valley ](https://expedia.co.uk/Ohio-River-Valley-Hotels.0-l6233674-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Drury Inn & Suites Sikeston, MO ](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) - [Pear Tree Inn Sikeston ](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) - [Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) ](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) - [Days Inn and Suites by Wyndham Sikeston ](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) - [Drury Plaza Hotel Cape Girardeau Conference Center ](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) - [The Riverview ](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) [See a list of all hotels in Scott County](https://expedia.co.uk/All-Scott-County-Hotels.d553248635976434022.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Scott County on Expedia.com ](https://www.expedia.com/Destinations-In-Scott-County.d553248635976434022.Hotel-Destinations) ### Expedia's Latest Trends Hotels - 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