Title: Hotels in Scott City, MO - Best Scott City Hotels from £48 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Scott City](https://expedia.co.uk/Scott-City-Holiday-Rentals.d553248634983544376.Travel-Guide-HolidayRentals)[Scott City Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Scott-City.d553248634983544376.Car-Hire-Guide)[Scott City Holidays](https://expedia.co.uk/Scott-City.d553248634983544376.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Scott City, MO from £48 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Scott City Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&amenities=PETS) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Scott+City%2C+Missouri%2C+United+States+of+America®ionId=553248634983544376&latLong=37.216718%2C-89.524534&adults=2&startDate=2025-12-14&d1=2025-12-14&endDate=2025-12-16&d2=2025-12-16&amenities=WATER_PARK) ## Check prices for these dates Tonight [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376&startDate=2025-11-30&endDate=2025-12-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Dec - 2 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376&startDate=2025-12-01&endDate=2025-12-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Scott City hotels and places to stay ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/f00e1c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1009) "A great stay in every aspect. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gertrude £54 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 9.0/10 Wonderful (436) "Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doncheial £81 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (441) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristen £81 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1013) "This was a wonderful stay. We will definitely stay again when we are in town!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trista £66 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/8874e729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1006) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine £69 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (657) "Stayed on our way south for vacation. It was a clean nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel £69 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/4329af11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/e7b8b662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (715) "Stayed one night. Good rate for the Hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £54 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/3c8c0a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1006) "Everything was clean, staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £67 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/dda7050d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (561) "The room was good a/c kept it cold " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £50 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout curtains, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO Charleston 6.6/10 (611) "Staff was great! Room was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lana £49 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1010) "Clean room, great location and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £78 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/664c9838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5be64f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/5641af73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (280) "Room was clean, breakfast was very good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie £72 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.2/10 Wonderful (37) "THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) AHMAD £94 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1008) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather £60 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/917691e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston Sikeston 9.0/10 Wonderful (8) "Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott £97 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (422) "Room was clean and had a refrigerator and microwave for use if needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry £48 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1007) "Nice place for a stay at a reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arthur £60 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Accessible, Non Smoking | Iron/ironing board, free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/0feda7c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/c71a6d1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 Cairo 6.6/10 (272) "Break fast was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Uma £61 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1009) "It was right off the interstate with lots of restaurant options " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly £81 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1006) "Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £77 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-15&endDate=2025-12-16®ionId=553248634983544376&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248634983544376) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FScott-City-Hotels.d553248634983544376.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FScott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) ## Top Scott City Hotel Reviews ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "It was great" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Nice quiet night" [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Very friendly people, clean rooms, comfortable bed, great breakfast," [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Everything was clean and comfortable. " [](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Friendly staff, clean room, comfortable beds and great breakfast" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Helpful staff, clean room." [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "We had a wonderful stay at this hotel. The room and common areas were spotless and the food was wonderful. Our children had a glorious time swimming in the indoor pool." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Clean room. Clean well stocked bathroom. Nice big bathroom. Very courteous check in attendent. And sweet lady serving breakfast. " [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "The room was spotless! The staff was great! Very satisfied! Excellent" [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ## More cheap stays in Scott City ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr Sikeston MO £54 2 Dec - 3 Dec includes taxes & fees 7.2/10 Good! (1,006 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy Cape Girardeau MO £60 7 Dec - 8 Dec includes taxes & fees 9/10 Wonderful! (1,004 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street Cape Girardeau MO £81 4 Dec - 5 Dec includes taxes & fees 9.4/10 Exceptional! (1,007 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St Cape Girardeau MO £60 5 Dec - 6 Dec includes taxes & fees 8.8/10 Excellent! (1,004 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO £81 21 Dec - 22 Dec includes taxes & fees 8.8/10 Excellent! (436 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Candlewood Suites Cape Girardeau by IHG 485 S Mount Auburn Rd Cape Girardeau MO £64 7 Dec - 8 Dec includes taxes & fees 8/10 Very Good! (873 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Scott City? > [Drury Plaza Hotel Cape Girardeau Conference Center](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information), located 6.9 mi (11.1 km) from the heart of Scott City, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are [The Riverview](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) and [Pear Tree Inn Cape Girardeau West](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376), or [vacation rentals in Scott City](https://www.expedia.co.uk/Scott-City-Holiday-Rentals.d553248634983544376.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Scott City has to offer? > [Building at Cape Girardeau Regional Airport](https://www.expedia.co.uk/Scott-City-Hotels-Building-At-Cape-Girardeau-Regional-Airport.h103892640.Hotel-Information): This highly rated holiday home rental in Scott City is near the airport and offers air conditioning to help you feel perfectly comfortable in your new surroundings. See all [vacation rentals in Scott City](https://www.expedia.co.uk/Scott-City-Holiday-Rentals.d553248634983544376.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Scott City, will I receive a refund? > Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983544376&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Scott City. ### What is staying in Scott City like? > Travellers to Scott City will find plenty to explore and enjoy. There are 115 hotels and other accommodation options in the surrounding area. Find out more about [Scott City](https://www.expedia.co.uk/Scott-City.dx553248634983544376). ### What is there to see in Scott City? > The picturesque setting of [Shawnee National Forest](https://www.expedia.co.uk/Shawnee-National-Forest-Illinois.d553248635944113522.Attraction) and [Mississippi River](https://www.expedia.co.uk/Mississippi-River-United-States-of-America.d6209928.Attraction) exemplify the area's natural beauty. You'll also find [Isle Casino Cape Girardeau](https://www.expedia.co.uk/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Attraction) and [Show Me Center](https://www.expedia.co.uk/Show-Me-Center-Sikeston.d693562494384107520.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Scott City guide](https://www.expedia.co.uk/Scott-City.dx553248634983544376). ### What's the seasonal weather in Scott City? > The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Scott City is 1491 mm. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Allenville Hotels](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Benton Hotels](https://www.expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bernie Hotels](https://www.expedia.co.uk/Bernie-Hotels.d3000349284.Travel-Guide-Hotels) - [Bertrand Hotels](https://www.expedia.co.uk/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels](https://www.expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomfield Hotels](https://www.expedia.co.uk/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Canalou Hotels](https://www.expedia.co.uk/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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[Perryville Hotels](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Sedgewickville Hotels](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Gay-Friendly-Hotel.0-0-d6058766-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Hotels-With-Indoor-Pools.0-0-d6058766-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Sikeston Hotels](https://www.expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Resorts in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotel-Resorts.d6058763-aaHotelResorts.Travel-Guide-Accommodation) - [Golf Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Golf-Hotels.0-0-d6058763-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotel-With-Connecting-Rooms.0-0-d6058763-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotels-With-Smoking-Rooms.0-0-d6058763-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Luxury-Hotel.0-0-d6058763-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Spa-Hotels.0-0-d6058763-tSpaHotels.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Wappapello Hotels](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Flights to Cape Girardeau](https://www.expedia.co.uk/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Flights to Dexter](https://www.expedia.co.uk/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights) - [Flights to Wappapello](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Cape Girardeau Municipal](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Sikeston Memorial Municipal](https://www.expedia.co.uk/lp/airports/sik/flights-from-sikeston-memorial-municipal-airport) - [Flights from Bernie](https://www.expedia.co.uk/lp/flights/3000349284/flights-from-bernie) - [Flights from Bertrand](https://www.expedia.co.uk/lp/flights/3000349285/flights-from-bertrand) - [Flights from East Prairie](https://www.expedia.co.uk/lp/flights/3000349349/flights-from-east-prairie) - [Flights from Gideon](https://www.expedia.co.uk/lp/flights/3000349377/flights-from-gideon) - [Flights from Risco](https://www.expedia.co.uk/lp/flights/3000349516/flights-from-risco) - [Flights from Dexter](https://www.expedia.co.uk/lp/flights/55097/flights-from-dexter) - [Flights from Fredericktown](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Altenburg](https://www.expedia.co.uk/lp/flights/553248634983289075/flights-from-altenburg) - [Flights from Zalma](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Frohna](https://www.expedia.co.uk/lp/flights/553248634983521632/flights-from-frohna) - [Flights from Wyatt](https://www.expedia.co.uk/lp/flights/553248634983534991/flights-from-wyatt) - [Flights from Jackson](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson) - [Flights from Marston](https://www.expedia.co.uk/lp/flights/55824/flights-from-marston) - [Flights from Sikeston](https://www.expedia.co.uk/lp/flights/6058766/flights-from-sikeston) - [Flights from Cape Girardeau](https://www.expedia.co.uk/lp/flights/820/flights-from-cape-girardeau) - [Flights from Poplar Bluff](https://www.expedia.co.uk/lp/flights/9449/flights-from-poplar-bluff) - [Flights from Atlanta (ATL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau) - [Flights from Birmingham (BHM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau) - [Flights from Mumbai (BOM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bom/cgi/mumbai-to-cape-girardeau) - [Flights from Sedalia (DMO) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau) - [Flights from Dublin (DUB) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from Los Angeles (LAX) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff) - [Flights from London (LHR) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau) - [Flights from Lewiston (LWS) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau) - [Flights from Carbondale (MDH) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff) - [Flights from Chicago (MDW) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Stow (MMN) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau) - [Flights from Pittsburgh (PIT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff) - [Flights from Pasco (PSC) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau) - [Flights from San Antonio (SAT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/sat/pof/san-antonio-to-poplar-bluff) - [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Tijuana (TIJ) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau) - [Bernie Holidays](https://www.expedia.co.uk/Bernie.d3000349284.Holidays-City-Breaks) - [Dexter Holidays](https://www.expedia.co.uk/Dexter.d55097.Holidays-City-Breaks) - [Visit Fredericktown](https://www.expedia.co.uk/Fredericktown.dx55114) - [Marston Holidays](https://www.expedia.co.uk/Marston.d55824.Holidays-City-Breaks) - [Visit New Madrid](https://www.expedia.co.uk/New-Madrid.dx3000445315) - [Visit Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff.dx9449) - [Sikeston Holidays](https://www.expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) - [Visit Sikeston](https://www.expedia.co.uk/Sikeston.dx6058766) - [Visit Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri.dx6058763) - [Ski Holiday Packages Southeast Missouri](https://www.expedia.co.uk/lp/theme-holidays/ski-holidays/6058763/Southeast-Missouri) - [Rental cars Cape Girardeau Municipal airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) - [Car hire Cape Girardeau](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau.d820.Car-Hire-Guide) - [Island Car Rentals Rental Cars in Cobalt](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Redspot Rental Cars in Oran](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers) - [United Rental Cars in Southeast Missouri](https://www.expedia.co.uk/United-Car-Rentals-In-Southeast-Missouri.d6058763-c1088.Car-Rental-Guide-Suppliers) - [Charleston Holiday Rentals](https://www.expedia.co.uk/Charleston-Holiday-Rentals.d7182.Travel-Guide-HolidayRentals) - [Things to do in Southeast Missouri](https://www.expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Hotels in Scott City on Expedia.com](https://www.expedia.com/Scott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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