Title: Hotels in Chaffee, MO - Best Chaffee Hotels from £43 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Chaffee](https://expedia.co.uk/Chaffee-Holiday-Rentals.d553248634983269107.Travel-Guide-HolidayRentals)[Chaffee Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Chaffee.d553248634983269107.Car-Hire-Guide)[Chaffee Holidays](https://expedia.co.uk/Chaffee.d553248634983269107.Holidays-City-Breaks) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Abbie Moon # Find hotels in Chaffee, MO from £43 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Chaffee Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Chaffee%2C+Missouri%2C+United+States+of+America®ionId=553248634983269107&latLong=37.180051%2C-89.65509&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Chaffee hotels and places to stay ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/5e8a3e29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston Sikeston 7.2/10 Good (1005) "Clean and comfortable " £54 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/a8b491ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston Sikeston 8.8/10 Excellent (404) "Nice property and friendly staff." £89 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1008) "Very convenient and great breakfast " £72 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down duvets, desk](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/7dc8a5d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG Sikeston 8.6/10 Excellent (431) "Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great." £84 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/e3fbcab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8df39481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/8fe6deab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Sikeston Sikeston 9.4/10 Exceptional (1010) "Wonderful place to stay" £66 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1008) "Was a clean room, nice staff, good parking " £72 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/c7be0f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Individually decorated, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/3727e01c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/8e494fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Living area | TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/a63c84b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) Sikeston 8.4/10 Very good (689) "Very quiet and comfortable " £43 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (634) "We had a restful stay very safe & clean! Friendly staff:)" £68 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/be665de4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Sikeston/Miner Area Sikeston 6.6/10 (557) "I enjoyed our stay" £51 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (417) "It was easy and quiet and an easy check in " £54 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/ea01e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub) | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO Sikeston 9.4/10 Exceptional (1002) "Very nice and quiet " £77 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/b77bd903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/af525dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/a915fb4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Sikeston I-55 Sikeston 8.4/10 Very good (271) "The facility was very nice. " £75 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1005) "Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. " £59 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1005) "Room was clean, it is an affordable option to stay for a day or two " £59 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1004) "It was right off the interstate with lots of restaurant options " £81 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1003) "Excellent place. Really friendly staff" £76 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/39cbec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston Sikeston 9.4/10 Exceptional (26) "Very clean and comfortable room. " £85 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1013) "Great place" £76 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (455) "The Staff was friendly The restaurant was good" £106 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/9a57fa49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (648) "nice stay" £49 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248634983269107&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FChaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ## Learn more about Chaffee Head to Isle Casino Cape Girardeau and Show Me Center—just two of the sights around Chaffee. [See all hotels in Chaffee](https://www.expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25&adults=2®ionId=553248634983269107) ![](https://mediaim.expedia.com/destination/2/c1b2471b51fb6a0569864d8f0d95d9a4.jpg?impolicy=fcrop&w=624&h=770&p=1&q=high) Photo by Bailey Swinford ## Top Chaffee Hotel Reviews ![Days Inn and Suites by Wyndham Sikeston](//images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Clean and comfortable " [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "The rooms are always amazing! When we go in its always so nice and cool. Loved having a k-cup in my room again. This is my favorite place in cape. My only complaint would be no microwave in the room for snacks and things. " [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The lady that checked me in was amazing!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Love to stay at any Drury. They do things right. Most friendly guest service staff around." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Hampton Inn Sikeston](//images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Clean and welcoming " [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Pear Tree Inn Sikeston](//images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg) ### Pear Tree Inn Sikeston 10/10 Excellent "Clean and welcoming" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "The room was very clean. Parking was very easy. Check in was very easy and the staff was great" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Convenient to St Francis Medical Center. It is quiet, staff is friendly and tge breakfast a plus " [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Very nice and quiet " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ## More cheap stays in Chaffee ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO £97 19 Oct - 20 Oct includes taxes & fees 9.2/10 Wonderful! (431 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO £59 12 Oct - 13 Oct includes taxes & fees 8.8/10 Excellent! (1,003 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO £59 12 Oct - 13 Oct includes taxes & fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr, Sikeston, MO £54 13 Oct - 14 Oct includes taxes & fees 7.2/10 Good! (1,002 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Sikeston 120 S Interstate Drive, Sikeston, MO £72 19 Oct - 20 Oct includes taxes & fees 8.2/10 Very Good! (1,003 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Sikeston 1240 Commerce Drive, Sikeston, MO £89 19 Oct - 20 Oct includes taxes & fees 8.8/10 Excellent! (404 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ## Frequently asked questions ### Where is the best place to stay in Chaffee? > [Drury Plaza Hotel Cape Girardeau Conference Center](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information), located 9.6 mi (15.5 km) from the heart of Chaffee, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are [The Riverview](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) and [La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107), or [vacation rentals in Chaffee](https://www.expedia.co.uk/Chaffee-Holiday-Rentals.d553248634983269107.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Chaffee has to offer? > [Little Blue Cottage on Spanish](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information): This holiday home rental outside of Chaffee comes with WiFi so that you can feel at home during your trip. See all [vacation rentals in Chaffee](https://www.expedia.co.uk/Chaffee-Holiday-Rentals.d553248634983269107.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Chaffee, will I receive a refund? > Yes! The majority of hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983269107&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Chaffee. ### What's it like to stay in Chaffee? > Visitors will definitely enjoy all that Chaffee has to offer. There are 103 hotels and other accommodation options in the surrounding area. Find out more about [Chaffee](https://www.expedia.co.uk/Chaffee.dx553248634983269107). ### What are the top places to visit in Chaffee? > Places to visit in the wider area include [Isle Casino Cape Girardeau](https://www.expedia.co.uk/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Attraction), [Show Me Center](https://www.expedia.co.uk/Show-Me-Center-Sikeston.d693562494384107520.Attraction) and [eDen Spa & Salon](https://www.expedia.co.uk/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Attraction). You'll also find [Cape Splash Family Aquatic Center](https://www.expedia.co.uk/Cape-Splash-Family-Aquatic-Center-Cape-Girardeau.d553248621532655772.Attraction) and [Cape Girardeau Conservation Nature Center](https://www.expedia.co.uk/Cape-Girardeau-Conservation-Nature-Center-Cape-Girardeau.d553248621532655773.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Chaffee guide](https://www.expedia.co.uk/Chaffee.dx553248634983269107). ### What's the seasonal weather like in Chaffee? > The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Chaffee is 1491 mm. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Allenville Hotels](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Benton Hotels](https://www.expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bernie Hotels](https://www.expedia.co.uk/Bernie-Hotels.d3000349284.Travel-Guide-Hotels) - [Bertrand Hotels](https://www.expedia.co.uk/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Blodgett Hotels](https://www.expedia.co.uk/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Bloomfield Hotels](https://www.expedia.co.uk/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Canalou Hotels](https://www.expedia.co.uk/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Historic Hotels in Cape Girardeau](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Historic-Hotel.0-0-d820-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Cape Girardeau Hotels](https://www.expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Catron Hotels](https://www.expedia.co.uk/Catron-Hotels.d3000349317.Travel-Guide-Hotels) - [Charleston Hotels](https://www.expedia.co.uk/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Dexter Hotels](https://www.expedia.co.uk/Dexter-Hotels.d55097.Travel-Guide-Hotels) - [East Prairie Hotels](https://www.expedia.co.uk/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels) - [Fisk Hotels](https://www.expedia.co.uk/Fisk-Hotels.d553248634983120615.Travel-Guide-Hotels) - [Fredericktown Hotels](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [Friedheim Hotels](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Jackson Hotels](https://www.expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Junction City Hotels](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Marble Hill Hotels](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Hotels with Restaurant in Marston](https://www.expedia.co.uk/Marston-Hotels-Hotel-With-Restaurant.0-0-d55824-thotelwithrestaurant.Travel-Guide-Filter-Hotels) - [Miner Hotels](https://www.expedia.co.uk/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Morehouse Hotels](https://www.expedia.co.uk/Morehouse-Hotels.d553248634983462037.Travel-Guide-Hotels) - [New Madrid Hotels](https://www.expedia.co.uk/New-Madrid-Hotels.d3000445315.Travel-Guide-Hotels) - [Oran Hotels](https://www.expedia.co.uk/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Perryville Hotels](https://www.expedia.co.uk/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Sedgewickville Hotels](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Gay-Friendly-Hotel.0-0-d6058766-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Sikeston](https://www.expedia.co.uk/Sikeston-Hotels-Hotels-With-Indoor-Pools.0-0-d6058766-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Sikeston Hotels](https://www.expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Resorts in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotel-Resorts.d6058763-aaHotelResorts.Travel-Guide-Accommodation) - [Golf Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Golf-Hotels.0-0-d6058763-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotel-With-Connecting-Rooms.0-0-d6058763-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotels-With-Smoking-Rooms.0-0-d6058763-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Luxury-Hotel.0-0-d6058763-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Spa-Hotels.0-0-d6058763-tSpaHotels.Travel-Guide-Filter-Hotels) - [Southeast Missouri Hotels](https://www.expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Hotels near Southeast Missouri State University](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [Wappapello Hotels](https://www.expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Flights to Cape Girardeau](https://www.expedia.co.uk/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Flights to Dexter](https://www.expedia.co.uk/Cheap-Flights-To-Dexter.d55097.Travel-Guide-Flights) - [Flights to Wappapello](https://www.expedia.co.uk/Cheap-Flights-To-Wappapello.d183505.Travel-Guide-Flights) - [Flights from Cape Girardeau Municipal](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Sikeston Memorial Municipal](https://www.expedia.co.uk/lp/airports/sik/flights-from-sikeston-memorial-municipal-airport) - [Flights from Bernie](https://www.expedia.co.uk/lp/flights/3000349284/flights-from-bernie) - [Flights from Bertrand](https://www.expedia.co.uk/lp/flights/3000349285/flights-from-bertrand) - [Flights from East Prairie](https://www.expedia.co.uk/lp/flights/3000349349/flights-from-east-prairie) - [Flights from Risco](https://www.expedia.co.uk/lp/flights/3000349516/flights-from-risco) - [Flights from Dexter](https://www.expedia.co.uk/lp/flights/55097/flights-from-dexter) - [Flights from Fredericktown](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Altenburg](https://www.expedia.co.uk/lp/flights/553248634983289075/flights-from-altenburg) - [Flights from Zalma](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Frohna](https://www.expedia.co.uk/lp/flights/553248634983521632/flights-from-frohna) - [Flights from Wyatt](https://www.expedia.co.uk/lp/flights/553248634983534991/flights-from-wyatt) - [Flights from Scott City](https://www.expedia.co.uk/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Jackson](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson) - [Flights from Marston](https://www.expedia.co.uk/lp/flights/55824/flights-from-marston) - [Flights from Sikeston](https://www.expedia.co.uk/lp/flights/6058766/flights-from-sikeston) - [Flights from Cape Girardeau](https://www.expedia.co.uk/lp/flights/820/flights-from-cape-girardeau) - [Flights from Poplar Bluff](https://www.expedia.co.uk/lp/flights/9449/flights-from-poplar-bluff) - [Flights from Atlanta (ATL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau) - [Flights from Birmingham (BHM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau) - [Flights from Mumbai (BOM) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/bom/cgi/mumbai-to-cape-girardeau) - [Flights from Sedalia (DMO) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau) - [Flights from Dublin (DUB) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from Los Angeles (LAX) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/lax/pof/los-angeles-to-poplar-bluff) - [Flights from London (LHR) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau) - [Flights from Lewiston (LWS) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau) - [Flights from Carbondale (MDH) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/mdh/pof/carbondale-to-poplar-bluff) - [Flights from Chicago (MDW) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Stow (MMN) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau) - [Flights from Pittsburgh (PIT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/pit/pof/pittsburgh-to-poplar-bluff) - [Flights from Pasco (PSC) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau) - [Flights from San Antonio (SAT) to Poplar Bluff (POF)](https://www.expedia.co.uk/lp/flights/sat/pof/san-antonio-to-poplar-bluff) - [Flights from St. Louis (STL) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Tijuana (TIJ) to Cape Girardeau (CGI)](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau) - [Bernie Holidays](https://www.expedia.co.uk/Bernie.d3000349284.Holidays-City-Breaks) - [Dexter Holidays](https://www.expedia.co.uk/Dexter.d55097.Holidays-City-Breaks) - [Visit Fredericktown](https://www.expedia.co.uk/Fredericktown.dx55114) - [Marston Holidays](https://www.expedia.co.uk/Marston.d55824.Holidays-City-Breaks) - [Visit New Madrid](https://www.expedia.co.uk/New-Madrid.dx3000445315) - [Visit Poplar Bluff](https://www.expedia.co.uk/Poplar-Bluff.dx9449) - [Sikeston Holidays](https://www.expedia.co.uk/Sikeston.d6058766.Holidays-City-Breaks) - [Visit Sikeston](https://www.expedia.co.uk/Sikeston.dx6058766) - [Visit Southeast Missouri](https://www.expedia.co.uk/Southeast-Missouri.dx6058763) - [Ski Holiday Packages Southeast Missouri](https://www.expedia.co.uk/lp/theme-holidays/ski-holidays/6058763/Southeast-Missouri) - [Rental cars Cape Girardeau Municipal airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) - [Car hire Cape Girardeau](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau.d820.Car-Hire-Guide) - [Island Car Rentals Rental Cars in Cobalt](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Redspot Rental Cars in Oran](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers) - [United Rental Cars in Southeast Missouri](https://www.expedia.co.uk/United-Car-Rentals-In-Southeast-Missouri.d6058763-c1088.Car-Rental-Guide-Suppliers) - [Charleston Holiday Rentals](https://www.expedia.co.uk/Charleston-Holiday-Rentals.d7182.Travel-Guide-HolidayRentals) - [Things to do in Southeast Missouri](https://www.expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Hotels in Chaffee on Expedia.com](https://www.expedia.com/Chaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](https://a.travel-assets.com/mad-service/qr-code/footer_qr/3_QR_FOOTER.png)