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Top cities in Cape Girardeau County

A nighttime view of a bridge with its cables illuminated against a starry sky.
Vacation Rentals

Cape Girardeau

Cape Girardeau

Check prices for these dates

In two weeks
27 Nov - 29 Nov
In two months
8 Jan - 10 Jan
In three months
5 Feb - 7 Feb
In four months
5 Mar - 7 Mar

Our top choices for Cape Girardeau County holiday rentals

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is £78
includes taxes & fees
16 Nov - 17 Nov
Little Blue Cottage on Spanish
A white building with a grey roof, two garage doors, and exterior lighting fixtures.

2. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is £139
includes taxes & fees
16 Nov - 17 Nov
The Cottage, Rusted Route Farms
A modern kitchen with grey cabinets, a wooden countertop, a coffee machine, and a welcome sign on the wall.

3. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is £142
includes taxes & fees
1 Dec - 2 Dec
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
An outdoor seating area with Adirondack chairs and a wooden pergola, surrounded by trees and string lights.

4. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is £159
includes taxes & fees
16 Nov - 17 Nov
The Little Château | Woodland Escape
An outdoor seating area with Adirondack chairs and a wooden pergola, surrounded by trees and string lights.

5. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is £167
includes taxes & fees
18 Nov - 19 Nov
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
A kitchen with wooden cabinets, a black microwave, a stove, and a refrigerator.

6. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (16 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is £132
includes taxes & fees
23 Nov - 24 Nov
Villa B offers peace and quiet with beautiful views of the countryside.
Property grounds

7. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"First time staying in the purple house, second time staying at the property. 10/10 recommend"
United States
Shawn A.
The price is £145
includes taxes & fees
16 Nov - 17 Nov
Purple Tiny House with Fire pit & Nature
Property grounds

8. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is £163
includes taxes & fees
16 Nov - 17 Nov
The Little Cape Lofted Cottage | Creek & Nature
An outdoor seating area with Adirondack chairs and a wooden pergola, surrounded by trees and string lights.

9. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"Very cute, especially because it's pet friendly! Currently building additional structures on site but appears almost complete and still a beautiful setting and property."
United States
Elizabeth K.
The price is £169
includes taxes & fees
16 Nov - 17 Nov
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
A wooden deck with a house on stilts, surrounded by trees.

10. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (42 reviews)
"The hosts were excellent."
United States
Jason L.
The price is £274
includes taxes & fees
7 Dec - 8 Dec
The Twisted Sassafras Treehouse
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

11. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is £217
includes taxes & fees
16 Nov - 17 Nov
Gorgeous 1856 Log Cabin, Completely Renovated
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

12. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (39 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is £132
includes taxes & fees
16 Nov - 17 Nov
Relax in the country at Countryside Villas! - Villa A
A two-story house with a large front yard, a swimming pool, and a fenced backyard.

13. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is £227
includes taxes & fees
16 Nov - 17 Nov
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A white porch with a swing, a white railing, and a view of a house and lawn.

14. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is £217
includes taxes & fees
16 Nov - 17 Nov
Beautifully Renovated Farmhouse in Jackson, MO
An aerial view of a house with a swimming pool, surrounded by dense greenery.

15. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (12 reviews)
"Nice place, great times"
United States
Jace W.
The price is £417
includes taxes & fees
16 Nov - 17 Nov
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A building with a dark exterior, a large window, and a sign that reads "The Atrium."

16. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (16 reviews)
"Great place to stay"
United States
Matt
The price is £76
includes taxes & fees
16 Nov - 17 Nov
The Atrium - A Boutique Hotel
A stone fireplace with a television mounted above it, a window with blinds, and a view of the outdoors.

17. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (80 reviews)
"Very clean and comfortable stay"
United States
Alison K.
The price is £132
includes taxes & fees
16 Dec - 17 Dec
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
A cozy room with a wooden table and chairs, a large window, and a door with a sign.

18. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (44 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is £94
includes taxes & fees
16 Nov - 17 Nov
Cozy cabins on beautiful Horseshoe Lake
A wooden deck with a table and chairs, surrounded by a wooden railing, overlooking a grassy area with trees.

19. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (432 reviews)
"Beautiful quaint cabin! Had everything you could need. Would definitely recommend to anyone looking for a nice place to stay."
United States
Brandon
The price is £163
includes taxes & fees
16 Nov - 17 Nov
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
A wooden-paneled room with a framed picture of dogs, a Keurig coffee maker, a tray with cups and a tissue box.

20. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (32 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is £94
includes taxes & fees
16 Nov - 17 Nov
The Rested Duck Mallard Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find holiday rentals that suit your style

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Apartments
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Top Cape Girardeau County Hotel Reviews

A modern kitchen with a bar area, a dining area with a sofa and chairs, and a large window with curtains.
Urban Lofts

Urban Lofts

Urban Lofts
Perryville

10/10 Excellent

Great place and will stay again when in the area!!!
United Kingdom
David Lee
Reviewed May 24, 2024
Urban Lofts

Find out more about Cape Girardeau County

Everything you need to know about Cape Girardeau County holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Cape Girardeau County holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cape Girardeau County holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search.

Cape Girardeau County holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cape Girardeau County. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Cape Girardeau County holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Cape Girardeau County holiday rentals we have selected for you start as low as £76 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Cape Girardeau County rentals

At Expedia, we put the best Cape Girardeau County holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Cape Girardeau County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cape Girardeau County holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cape Girardeau County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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