Title: Top Hotels in Cape Girardeau County - Compare Cape Girardeau County Hotels | Expedia.co.uk

[Holiday Rentals in Cape Girardeau County](https://expedia.co.uk/Destinations-In-Cape-Girardeau-County.d553248635976430467.Holiday-Rental-Destinations)[Cape Girardeau County Car Hire](https://expedia.co.uk/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Hire-Destinations)[Cape Girardeau County Holidays](https://expedia.co.uk/Cape-Girardeau-County.d553248635976430467.Holidays-City-Breaks)

![Beautiful city by the Mississippi River](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Alice Burghart

![](https://images.trvl-media.com/place/820/c000ed90-c592-47c7-a850-3eeb29bbc936.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Cape Girardeau County Accommodation: Most Popular Cities to Stay

![](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Cape Girardeau

[](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)

## Check prices for these dates

Tonight

[10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Cape Girardeau County hotels

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c65fb6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/db8c9491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(1,000 reviews)

"Great place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly

£82

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Grand Riverview Two Queen Room | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run films](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/e87009c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/f27091ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Riverview

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(501 reviews)

"The room was clean and I was able to check in a bit early."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sara

£77

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/ffb58563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/84598bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Cape Girardeau

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(1,006 reviews)

"Awesome stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Breckin

£74

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Jackson MO

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

Jackson

9.6/10

Exceptional

(1,010 reviews)

"Suited our purpose for overnight on a road trip "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela

£62

includes taxes & fees

18 Feb - 19 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/71011e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Accessible (Tub) | Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/86c003aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/fe0d924e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f71e5ca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau West

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

Cape Girardeau

9.0/10

Wonderful

(1,000 reviews)

"The staff were all very friendly. The room was clean and the beds were nice. Bathroom was very clean and comfortable "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fred

£59

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/75079b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/f7d52bda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Cape Girardeau by IHG

[](https://www.expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

Cape Girardeau

8.2/10

Very good

(894 reviews)

"Room was clean and spacious."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

George

£70

includes taxes & fees

1 Mar - 2 Mar

[](https://www.expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

[](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

Jackson

9.0/10

Wonderful

(702 reviews)

"Conveniently located, clean, friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Philip

£67

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Cape Girardeau Downtown

[](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(488 reviews)

"Very nice hotel!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angie

£104

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/44b66206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c66d7d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Cape Girardeau North

[](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

Cape Girardeau

7.2/10

Good

(698 reviews)

"The room was clean and nice. The breakfast was really good."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kalani

£48

includes taxes & fees

26 Feb - 27 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Cape Girardeau

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(157 reviews)

"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

£77

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/182edc95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom (Feature) | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

[](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

Cape Girardeau

9.4/10

Exceptional

(1,000 reviews)

"Breakfast was very good and staff was extremely friendly and rooms were very clean "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rex

£78

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/006e0795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

Cape Girardeau

9.0/10

Wonderful

(1,001 reviews)

"Staff great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nancy

[](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/e6e29f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/051de21c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/b20a49e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/81fbb6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Cape Girardeau I 55 East

[](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(791 reviews)

"Excellent stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina

£87

includes taxes & fees

19 Feb - 20 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information)

![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru By Hilton Cape Girardeau

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

Cape Girardeau

9.6/10

Exceptional

(109 reviews)

"It was a nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Douglas

£74

includes taxes & fees

18 Feb - 19 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/464a0039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking (NRF) | Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/1f46462a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/f2b68c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Town House Inn Cape Giradreau

[](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information)

Cape Girardeau

6.2/10

(210 reviews)

"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

£51

includes taxes & fees

8 Mar - 9 Mar

[](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/0ac4753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Jackson-Cape Girardeau

[](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

Jackson

8.2/10

Very good

(741 reviews)

"Clean and comfortable every time. This is a “go to” hotel "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jacqulyn

£67

includes taxes & fees

22 Feb - 23 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information)

![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room, 2 Queen Beds, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/affd3e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/ef0f7e68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Town House Inn

[](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

Jackson

7.6/10

Good

(433 reviews)

"The staff member Tim was very friendly and nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julie

£52

includes taxes & fees

14 Mar - 15 Mar

[](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a236a8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/9f324b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/7794c781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rockwood Inn

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information)

Cape Girardeau

10/10

Exceptional

(19 reviews)

"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kim

£128

includes taxes & fees

18 Feb - 19 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/3867ac72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Blue Cottage on Spanish

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

Cape Girardeau

8.4/10

Very good

(50 reviews)

"Cozy and perfect for a couple. Great communication with the host"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth G.

£77

includes taxes & fees

13 Feb - 14 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/469a5901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/6a739ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/211494f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/72000000/71750000/71745700/71745619/d33a9d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

Cape Girardeau

8.8/10

Excellent

(39 reviews)

"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emily D.

£158

includes taxes & fees

15 Feb - 16 Feb

[](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Colorful-Oasis-5mins-To-DownTown-Lush-Yard-W-Summer-PoolVENUE-Now-Open.h71745619.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-25&endDate=2026-02-26&regionId=553248635976430467&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Great weekend hotel deals in Cape Girardeau County, MO

### 

Showing deals for:**20 Feb - 22 Feb**

### Image gallery for Urban 2-bedroom Escape in Downtown Cape Girardeau 

![Exterior detail](https://images.trvl-media.com/lodging/110000000/109930000/109929600/109929505/23d7d447.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Urban 2-bedroom Escape in Downtown Cape Girardeau 

Cape Girardeau

**10/10**Exceptional (9 reviews)

7% off

£342

for 2 nights, 1 home

£171 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=109929505&adults=2)

### Image gallery for Little Blue Cottage on Spanish

![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Little Blue Cottage on Spanish

Cape Girardeau

**8.4/10**Very good (50 reviews)

9% off

£136

for 2 nights, 1 home

£68 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=45712431&adults=2)

### Image gallery for La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

**9.0/10**Wonderful (702 reviews)

15% off

£208

for 2 nights, 1 room

£104 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=53348099&adults=2)

### Image gallery for Rockwood Inn

![Lobby](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/5950187f.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Rockwood Inn

Cape Girardeau

**10/10**Exceptional (19 reviews)

10% off

£328

for 2 nights, 1 room

£164 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=105486893&adults=2)

### Image gallery for The Riverview

![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### The Riverview

Cape Girardeau

**9.4/10**Exceptional (501 reviews)

10% off

£293

for 2 nights, 1 room

£147 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=105081384&adults=2)

### Image gallery for Comfort Suites Jackson-Cape Girardeau

![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high)

### Comfort Suites Jackson-Cape Girardeau

Jackson

**8.2/10**Very good (741 reviews)

15% off

£147

for 2 nights, 1 room

£74 per night

includes taxes & fees

[](https://www.expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-22&selected=2555896&adults=2)

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## Top Cape Girardeau County Hotel Reviews

![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg)

### The Riverview

10/10 Excellent

"room was great, clean!!"

[](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)

![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg)

### Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Such a pretty hotel and the room was amazing!"

[](https://expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"From our room, to food; this was one of the best experiences that we’ve had with hotel travel. The breakfast rivaled a restaurant, the evening snacks and beverages were above board. The staff was friendly, the rooms were clean. The location is fantastic with Outback right beside the hotel and shopping and conveniences very close. I would recommend this establishment, we will be staying here again"

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Great "

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg)

### Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent

"Clean, roomy and priced right. "

[](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information)

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"The room was great. The facility was excellent. The people were excellent. Definitely going back."

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

10/10 Excellent

"Room was very clean. Staff was very knowledgeable and courteous. Excellent staff in every department. "

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg)

### Town House Inn

10/10 Excellent

"Yes"

[](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information)

![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg)

### Tru By Hilton Cape Girardeau

10/10 Excellent

"Very nice room!"

[](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

## Explore a world of travel with Expedia

- Explore a world of travel with Expedia

### Top cities in Cape Girardeau County

- [Cape Girardeau Hotels ](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels)
- [Jackson Hotels ](https://expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels)
- [Oak Ridge Hotels ](https://expedia.co.uk/Oak-Ridge-Hotels.d553248634983311120.Travel-Guide-Hotels)
- [Whitewater Hotels ](https://expedia.co.uk/Whitewater-Hotels.d553248634983531015.Travel-Guide-Hotels)
- [Friedheim Hotels ](https://expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels)
- [Dutchtown Hotels ](https://expedia.co.uk/Dutchtown-Hotels.d3000349346.Travel-Guide-Hotels)
- [Delta Hotels ](https://expedia.co.uk/Delta-Hotels.d553248634983422827.Travel-Guide-Hotels)
- [Allenville Hotels ](https://expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels)

### Hotels near popular Attractions

- [Hotels near Southeast Missouri State University ](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels)

### Explore more hotels

- [Drury Plaza Hotel Cape Girardeau Conference Center ](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)
- [The Riverview ](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information)
- [Drury Inn & Suites Cape Girardeau ](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)
- [Pear Tree Inn Cape Girardeau West ](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)
- [Drury Inn & Suites Jackson MO ](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)
- [Courtyard by Marriott Cape Girardeau Downtown ](https://expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information)

[See a list of all hotels in Cape Girardeau County](https://expedia.co.uk/All-Cape-Girardeau-County-Hotels.d553248635976430467.Travel-Guide-City-All-Hotels)

### More ways to book

- [Book Hotels in Cape Girardeau County on Expedia.com ](https://www.expedia.com/Destinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)

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