Title: Top Hotels in Cape Girardeau County - Compare Cape Girardeau County Hotels | Expedia.co.uk [Holiday Rentals in Cape Girardeau County](https://expedia.co.uk/Destinations-In-Cape-Girardeau-County.d553248635976430467.Holiday-Rental-Destinations)[Cape Girardeau County Car Hire](https://expedia.co.uk/Destinations-In-Cape-Girardeau-County.d553248635976430467.Car-Hire-Destinations)[Cape Girardeau County Holidays](https://expedia.co.uk/Cape-Girardeau-County.d553248635976430467.Holidays-City-Breaks) ![The Missouri State Tree - Dogwood](https://images.trvl-media.com/place/553248634983269107/3aabcda1-7e0a-4df4-9788-5f9645899bfb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Abbie Moon # Find the best Cape Girardeau County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Cape Girardeau County Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&lodging=CABIN) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Cape+Girardeau+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976430467&latLong=37.382832%2C-89.668449&adults=2&startDate=2025-11-25&d1=2025-11-25&endDate=2025-11-27&d2=2025-11-27&amenities=HOT_TUB) ## Cape Girardeau County Accommodation: Most Popular Cities to Stay ![](https://mediaim.expedia.com/destination/2/5b27a574bbd8c4a139204e48a625a1c7.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Cape Girardeau [](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) ## Check prices for these dates Tonight [11 Nov - 12 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2025-11-11&endDate=2025-11-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Nov - 13 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976430467&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Cape Girardeau County ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1000) "Clean room and amenities were great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal £77 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/8ba17328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview Cape Girardeau 9.4/10 Exceptional (450) "Location was perfect for family weekend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly £79 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8571b84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (648) "Stayed on our way south for vacation. It was a clean nice place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joel £69 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/f32a343b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1000) "Staff very accommodating and everything was very clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dericka £60 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/5b2269be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1003) "Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £77 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1009) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £71 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1005) "Always enjoy our stay. Staff is very friendly, especially at breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £60 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (89) "It was very nice and close, really loved the cookies and milk highly recommended" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) lee £75 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/4de18ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/cc0ef67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG Cape Girardeau 8.2/10 Very good (868) "Great staff and convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Greg £70 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (673) "Overall was wonderful customer service and breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie £54 includes taxes & fees 20 Nov - 21 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1000) "Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Penny £85 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (136) "Great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Will £75 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/68c09770.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (461) "Very clean and upscale hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike £100 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/4c2e6495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (769) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £84 includes taxes & fees 29 Nov - 30 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (420) "Room was clean and had a refrigerator and microwave for use if needed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherry £57 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/7adb4452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/5d555857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/674edecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau Cape Girardeau 6.0/10 (204) "I was okay for one quick night in a very convenient location for me." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andreas £62 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/bb7f277a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (738) "Great area, fast check in, quiet, very spacious" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeanne £71 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/dbe031d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a102ce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/000a3467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn Cape Girardeau 10/10 Exceptional (17) "Very beautiful property and we loved the old school feel and hospitality" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £118 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/9ff1a808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/927199d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/143b0eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/46000000/45720000/45712500/45712431/1e8bea93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Blue Cottage on Spanish Cape Girardeau 8.6/10 Excellent (46) "We stayed here to visit our two children going to SEMO. Everything about the place was perfect for a couple. The place was cute and the location was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth G. £80 includes taxes & fees 15 Nov - 16 Nov [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Little-Blue-Cottage-On-Spanish.h45712431.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/104000000/103750000/103741400/103741323/503e8265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/104000000/103750000/103741400/103741323/2a4eba1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103750000/103741400/103741323/87761e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103750000/103741400/103741323/d9b977d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau Jackson 9.4/10 Exceptional (3) "Always friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terry [](https://www.expedia.co.uk/Jackson-Hotels-Best-Western-Plus-Jackson-Cape-Girardeau.h103741323.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27®ionId=553248635976430467&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Cape-Girardeau-County.d553248635976430467.Hotel-Destinations) ## Top Cape Girardeau County Hotel Reviews ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Everything!" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Yes" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "1 of the best places ive stayed at! Extremely friendly service, 530 kickback which includes food and cocktails...and a decent breakfast. Room was nice..bed super comfy, pool area clean and nice.. Superb place for the price. Manager on duty was fantastic...all the staff were super friendly. " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The room was clean and comfy. The staf was friendly, courteous and efficient. Many thanks!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Clean and easy" [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Town House Inn](//images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "Appears to have been recently remodeled and updated. The room was fairly clean but could use a few cosmetic touches. Staff was courteous. We were only there for one night but this would be a great place to stay for an extended time as it had full kitchen amenities. No breakfast but the cost of the room made up for that. Hardee’s is within walking distance. We would definitely stay here again. " [](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "The eggs were fake and the turkey sausage was bad " [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Always great service and awesome accomodations." [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](//images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Fairly new building in a new area of town. Very convenient as right off the freeway. 2 Q room, typical Fairfield bath setup except a tub/shower instead of shower as we’ve seen in every other Fairfields. Ave size room but adequate. Good cleanliness. Good breakfast, cage free eggs, bacon, sausage, 2 waffle makers, etc, good coffee. We would stay here again if needed. " [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Cape Girardeau County - [Cape Girardeau Hotels](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Jackson Hotels](https://expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Oak Ridge Hotels](https://expedia.co.uk/Oak-Ridge-Hotels.d553248634983311120.Travel-Guide-Hotels) - [Whitewater Hotels](https://expedia.co.uk/Whitewater-Hotels.d553248634983531015.Travel-Guide-Hotels) - [Dutchtown Hotels](https://expedia.co.uk/Dutchtown-Hotels.d3000349346.Travel-Guide-Hotels) - [Delta Hotels](https://expedia.co.uk/Delta-Hotels.d553248634983422827.Travel-Guide-Hotels) - [Allenville Hotels](https://expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Friedheim Hotels](https://expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Southeast Missouri State University](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Drury Plaza Hotel Cape Girardeau Conference Center](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) - [The Riverview](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) - [Pear Tree Inn Cape Girardeau West](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) - [Pear Tree Inn Cape Girardeau Near the Medical Center](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) - [Tru By Hilton Cape Girardeau](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) - [Drury Inn & Suites Cape Girardeau](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)