A rocky stream surrounded by trees and foliage.

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Our top choices for Cape Girardeau County holiday rentals

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
United States
Jeremy W.
The price is £85
includes taxes & fees
1 Oct - 2 Oct
Little Blue Cottage on Spanish
A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

2. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is £154
includes taxes & fees
5 Oct - 6 Oct
The Cottage, Rusted Route Farms
A dining area with a table and chairs, a window with blinds, a kitchen with appliances, and a ceiling light fixture.

3. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is £136
includes taxes & fees
20 Oct - 21 Oct
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

4. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (38 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is £139
includes taxes & fees
19 Oct - 20 Oct
Relax in the country at Countryside Villas! - Villa A
Exterior

5. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is £176
includes taxes & fees
1 Oct - 2 Oct
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
A compact kitchen with wooden cabinets and a dining area with a table and chairs.

6. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (14 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is £139
includes taxes & fees
19 Oct - 20 Oct
Villa B offers peace and quiet with beautiful views of the countryside.
Exterior

7. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
The price is £156
includes taxes & fees
1 Oct - 2 Oct
Purple Tiny House with Fire pit & Nature
Private kitchen

8. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is £182
includes taxes & fees
1 Oct - 2 Oct
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Ground floor of the Euro

9. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is £170
includes taxes & fees
1 Oct - 2 Oct
The Little Château | Woodland Escape
Exterior

10. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is £175
includes taxes & fees
1 Oct - 2 Oct
The Little Cape Lofted Cottage | Creek & Nature
Private kitchen

11. Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.

Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.
Friedheim
The price is £187
includes taxes & fees
1 Oct - 2 Oct
Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

12. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is £239
includes taxes & fees
5 Oct - 6 Oct
Gorgeous 1856 Log Cabin, Completely Renovated
A two-story house with a front porch, a small garden, and a white picket fence.

13. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (44 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is £237
includes taxes & fees
1 Oct - 2 Oct
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A modern living room with a wooden ceiling, a stone fireplace, a TV mounted on the wall, and a bar area with stools.

14. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (38 reviews)
"Amazing stay! Everything was perfect."
United States
Wayne F.
The price is £293
includes taxes & fees
4 Oct - 5 Oct
The Twisted Sassafras Treehouse
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

15. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is £239
includes taxes & fees
5 Oct - 6 Oct
Beautifully Renovated Farmhouse in Jackson, MO
A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

16. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is £438
includes taxes & fees
1 Oct - 2 Oct
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

17. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.8 out of 10, Exceptional, (8 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is £121
includes taxes & fees
1 Oct - 2 Oct
The Atrium - A Boutique Hotel
A red barn with a sloped roof, surrounded by a grassy field and trees.

18. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is £127
includes taxes & fees
6 Oct - 7 Oct
The Weber Farm - Enjoy a beautiful 100 acre farm!
A rustic cabin with a stone chimney, wooden deck, and a porch.

19. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.8 out of 10, Exceptional, (52 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
The price is £180
includes taxes & fees
14 Oct - 15 Oct
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
A log cabin with a metal roof, two windows, a door, and a porch with two rocking chairs and a small table.

20. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (428 reviews)
"Beautiful quaint cabin! Had everything you could need. Would definitely recommend to anyone looking for a nice place to stay."
United States
Brandon
The price is £162
includes taxes & fees
1 Oct - 2 Oct
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"No complaints"
Don 3-night trip
Posted 6 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Find out more about Cape Girardeau County

Holiday Apartments in Cape Girardeau County

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