Compare and book 5 Star hotels in Panama City, Panamá Province
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Panama City 5 Star Hotels
Top Panama City 5 Star Hotels
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
9.0 out of 10, Wonderful, (2392)
The price is £96
includes taxes & fees
29 May - 30 May
JW Marriott Panama
JW Marriott Panama
8.8 out of 10, Excellent, (1001)
The price is £168
includes taxes & fees
18 May - 19 May
W Panama
W Panama
8.8 out of 10, Excellent, (977)
The price is £161
includes taxes & fees
5 Jun - 6 Jun
Save an average of 15% on thousands of hotels when you're signed in
Waldorf Astoria Panama
Waldorf Astoria Panama
9.0 out of 10, Wonderful, (938)
The price is £189
includes taxes & fees
17 May - 18 May
Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (215)
The price is £257
includes taxes & fees
1 Jun - 2 Jun
The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
8.0 out of 10, Very good, (899)
The price is £138
includes taxes & fees
26 May - 27 May
Hilton Panama
Hilton Panama
8.8 out of 10, Excellent, (1000)
The price is £189
includes taxes & fees
2 Jun - 3 Jun
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (469)
The price is £184
includes taxes & fees
8 Jun - 9 Jun
Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1001)
The price is £180
includes taxes & fees
26 May - 27 May
Villa Palma Boutique Hotel
Villa Palma Boutique Hotel
9.4 out of 10, Exceptional, (276)
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Riande Aeropuerto Hotel & Casino
Vía Tocumen, Entrance to Corredor Sur, Tocumen, Panama
The price is £77 per night from May 24 to May 25
£77
per night
24 May - 25 May
8.2/10 Very Good! (1,528 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Panama City Hotel Reviews
Panama City Hotel Reviews
5/5 Excellent
"Very convenient for food and market "
A verified traveller stayed at Hotel Riu Plaza Panama
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Panama City by Star Rating
Choose Your Panama City Hotel Style
- Beach Resorts & Hotels (31)
- Boutique Hotels (16)
- Business Hotels (97)
- Casino Hotels (105)
- Cheap Hotels (56)
- Family-Friendly Hotels (86)
- Golf Hotels (15)
- Historic Hotels (111)
- Hotels with Air Conditioning (144)
- Hotels with Airport Transfers (90)
- Hotels with Babysitting Services (20)
- Hotels with Balcony (44)
- Hotels with Breakfast (123)
- Hotels with Connecting Rooms (28)
- Hotels with Entertainment (40)
- Hotels with Gym (60)
- Hotels with Hot Tubs (24)
- Hotels with Laundry Service (116)
- Hotels with Parking (110)
- Hotels with Pool (88)
- Hotels with a Bar (93)
- Hotels with a View (74)
- Hotels with smoking rooms (39)
- Luxury Hotels (48)
- Pet-Friendly Hotels (24)
- Romantic Hotels (20)
- Shopping Hotels (111)
- Spa Hotels (45)
- Sports Hotels (49)
- Wedding Hotels (38)
More accommodation types in Panama City
Most Popular Hotels in Panama City
- Marriott Panama Hotel
- Hotel Ojos del Rio
- Riande Urban Hotel
- AC Hotel by Marriott Panama City
- Holiday Inn Panama Distrito Financiero, an IHG Hotel
- TRYP by Wyndham Panamá Centro
- Sofitel Legend Casco Viejo, Panama City
- Hilton Panama
- Hospedium Princess Hotel Panama
- The Executive Hotel
- Central Hotel Panama Casco Viejo
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Residence Inn by Marriott Panama City
- MARINN PLACE Financial District
- Radisson Hotel Panama Canal
- Studio Coliving
- Hotel La Compania, in the Unbound Collection by Hyatt
- Sortis Hotel, Spa & Casino, Autograph Collection
- Marriott Executive Apartments Panama City, Finisterre