A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City 4 Star Hotels

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Panama City 4-star hotels

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Duran
£116
includes taxes & fees
10 Nov - 11 Nov
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.
A building with a balcony and a street view.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
£186
includes taxes & fees
9 Nov - 10 Nov
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
A modern spa area with a hot tub, seating, and a city view.
A rooftop pool area with purple lounge chairs and a city skyline in the background.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
benjamin
£110
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
Pool
A balcony with a view of a swimming pool, palm trees, and city buildings.
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.
A reception area with marble reception desks and a sign indicating the reception desk.

4. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
Althea
£93
includes taxes & fees
26 Oct - 27 Oct
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A balcony with wicker chairs and a view of the cityscape.
A rooftop pool area with a view of high-rise buildings in the background.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Luis
£81
includes taxes & fees
10 Nov - 11 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A resort with a pool, palm trees, and a building with a red roof.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Babak
£210
includes taxes & fees
14 Oct - 15 Oct
Dreams Playa Bonita Panama - All Inclusive
A trampoline with a safety net in a grassy area with trees in the background.
A reception area with a receptionist, a statue, and a digital display.
A conference room with a long table, chairs, and a carpeted floor.
A swimming pool with a bridge, surrounded by lush greenery and a seating area with tables and chairs.

7. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Lucas
£90
includes taxes & fees
20 Oct - 21 Oct
Riande Aeropuerto Hotel & Casino
A modern building with a glass facade, a curved structure, and a flat roof.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
£72
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A buffet with various food items including fruits, juices, and cheeses.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
A gym with treadmills, weight machines, and dumbbells.

9. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Chaloma
£84
includes taxes & fees
6 Nov - 7 Nov
Courtyard by Marriott Panama Metromall
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.

10. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
SHARROW
£98
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.

11. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
£125
includes taxes & fees
30 Oct - 31 Oct
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

12. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Calvin
£148
includes taxes & fees
24 Oct - 25 Oct
Marriott Panama Hotel
A hotel room with a sofa, a coffee table, a TV, and a cabinet.
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'

13. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.
A bar area with a curved counter, multiple screens, and a patterned carpet.

14. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Bruno
£110
includes taxes & fees
5 Nov - 6 Nov
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.

15. Novotel Panama City

Novotel Panama City
Bella Vista
United States
CARLOS
£97
includes taxes & fees
8 Nov - 9 Nov
Novotel Panama City
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.
A bar area with a counter, stools, and a seating area with tables and chairs.
A formal dining area with round tables, white tablecloths, and blue lace borders.

16. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United States
Si Ming
£65
includes taxes & fees
16 Oct - 17 Oct
Radisson Hotel Panama Canal
A buffet with various food items and a decorative plant.
A spa area with a hot tub, candles, and a curved bench.
A gym with treadmills, weight machines, and a red carpet.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.

17. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Nicole
£153
includes taxes & fees
31 Oct - 1 Nov
Sheraton Grand Panama
A poolside area with covered seating and palm trees.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.
A modern living room with a city view, a flat-screen TV, and a dining area with white chairs and a table.

18. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Jahzenia
£224
includes taxes & fees
21 Oct - 22 Oct
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A spacious lobby with a tiled floor, large windows, and potted plants.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

19. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
Ashleigh-Ann
£166
includes taxes & fees
14 Oct - 15 Oct
American Trade Hotel
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A rooftop terrace with a city skyline view, a pool, and outdoor seating.
A restaurant with a wine display and a table set for two.
A bedroom with a large bed, a stone wall, a wooden bench, and a hanging light fixture.

20. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Naveera Jyoti
£55
includes taxes & fees
11 Nov - 12 Nov
Hotel Casa Panamá
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
£110
21 Oct - 22 Oct
includes taxes & fees
9/10 Wonderful! (6,079 reviews)
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
£218
31 Oct - 1 Nov
includes taxes & fees
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
£292
3 Nov - 4 Nov
includes taxes & fees
9.8/10 Exceptional! (759 reviews)
Sofitel Legend Casco Viejo, Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

10/10 Excellent
"Its verry easy access to nearby malls and nightlife its great locationa and convenient all together"
Deon 1-night trip
Posted 6 hours ago
Waymore Hotel Spa & Casino
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"Very well maintained, comfortable and great location (inside Multiplaza Mall)"
Carolina 2-night trip
Posted 11 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

8/10 Good
"Dirty and dark reception. Very clean room and friendly staff. Good breakfast. Stayed only for one night."
Ana Ines 1-night trip
Posted 12 hours ago
Las Americas Golden Tower Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"Great"
Aida Patricia 2-night trip
Posted 14 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"Excelente lugar y centrico para todo en la Ciudad."
Jose 4-night trip
Posted 16 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica

Find out more about Panama City

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that's popular among Expedia customers. An art gallery and proposal/romance packages are just a couple of its amenities. Travellers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From a swimming pool to a steam room, it offers conveniences that cater to every aspect of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.
  • Search for the lowest price from £110
What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveller experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City holiday. These types of accommodation generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.

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