Compare and book 4 Star hotels in Panama City, Panamá Province
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama City 4 Star Hotels
Our top choices for Panama City 4-star hotels
8.6 out of 10, Excellent, (2,573 reviews)
"Great place to stay, restaurant is great also"
Janet
The price is £112
includes taxes & fees
15 Jun - 16 Jun
8.8 out of 10, Excellent, (943 reviews)
"Breakfast was great, rooms very clean"
juanita
The price is £83
includes taxes & fees
26 Jun - 27 Jun
8.6 out of 10, Excellent, (1,000 reviews)
"Excellent location, good parking."
Mark
The price is £74
includes taxes & fees
5 Jun - 6 Jun
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza MallSan Francisco
9.0 out of 10, Wonderful, (1,006 reviews)
"Nice to be near shopping mall "
Patrick
The price is £97
includes taxes & fees
21 Jun - 22 Jun
9.0 out of 10, Wonderful, (1,020 reviews)
"Breakfast was great and free"
Trevan
The price is £128
includes taxes & fees
12 Jun - 13 Jun
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Hotel El Panama by Faranda Grand, a member of Radisson IndividualsBella Vista
7.8 out of 10, Good, (1,000 reviews)
"Friendly staff, clean and the breakfast had many options"
Reyna
The price is £102
includes taxes & fees
14 Jun - 15 Jun
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta PacificaSan Francisco
9.6 out of 10, Exceptional, (1,212 reviews)
"Beautiful and conveniently located.So clean enjoyed the complimentary breakfast close to shopping food .Would stay again."
Alethia
The price is £88
includes taxes & fees
30 May - 31 May
9.4 out of 10, Exceptional, (742 reviews)
"Clean and spacious Room, great location, helpful and friendly staff. "
Ricardo
The price is £228
includes taxes & fees
4 Jun - 5 Jun
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is £114 per night from 29 Jun to 30 Jun
£114
29 Jun - 30 Jun
includes taxes & fees
9/10 Wonderful! (5,501 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.
Top Panama City Hotel Reviews
Las Americas Golden Tower Panama
10/10 Excellent
Find out more about Panama City
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Albrook Shopping Mall
- Hotels near Ancon Hill
- Barrio Chino Hotels
- Gay-Friendly Hotels in Bella Vista
- Hotels with Laundry Service in Bella Vista
- Bella Vista Hotels
- Calidonia Hotels
- Gay-Friendly Hotels in Campo Alegre
- Campo Alegre Hotels
- Boutique Hotels in Casco Viejo
- Hilton Hotels in Casco Viejo
- Historic Hotels in Casco Viejo
- Wedding Hotels in Casco Viejo
- Casco Viejo Hotels
- Hotels near Cinta Costera
- Curundu Hotels
- All-Inclusive Hotels in Panamá Province
- Gay-Friendly Hotels in Panamá Province
- Panamá Province Hotels
- El Cangrejo Hotels
- Hotels near Estación Lotería
- Marbella Hotels
- Hotels near Marcos A. Gelabert Intl.
- Hotels near Multicentro Panama
- Obarrio Hotels
- Gay-Friendly Hotels in Punta Pacifica
- Punta Pacifica Hotels
- Pet-Friendly Hotels in Punta Paitilla
- Punta Paitilla Hotels
- San Felipe Hotels
- San Francisco Hotels
- Santa Ana Hotels
- Hotels near Vía Argentina
- Flights to Marcos A. Gelabert Intl.
- Flights from Marcos A. Gelabert Intl.
- Hahn Air Technologies Bocas del Toro (BOC) to Panama City (PAC) flights
- Flights from Bilbao (BIO) to Panama City (PAC)
- Flights from Bocas del Toro (BOC) to Panama City (PAC)
- Flights from Baltimore (BWI) to Panama City (PAC)
- Flights from Belize City (BZE) to Panama City (PAC)
- Flights from Columbia (CAE) to Panama City (PAC)
- Flights from Waco Kungo (CEO) to Panama City (PAC)
- Flights from Changuinola (CHX) to Panama City (PAC)
- Flights from Chi Mei (CMJ) to Panama City (PAC)
- Flights from Cartagena (CTG) to Panama City (PAC)
- Flights from David (DAV) to Panama City (PAC)
- Flights from Delhi (DEL) to Panama City (PAC)
- Flights from Durban (DUR) to Panama City (PAC)
- Flights from Dubai (DXB) to Panama City (PAC)
- Flights from La Fortuna (FON) to Panama City (PAC)
- Flights from Frankfurt (FRA) to Panama City (PAC)
- Flights from Ghimbi (GHD) to Panama City (PAC)
- Flights from Glasgow (GLA) to Panama City (PAC)
- Flights from Guatemala City (GUA) to Panama City (PAC)
- Flights from Guayaquil (GYE) to Panama City (PAC)
- Flights from Hong Kong (HKG) to Panama City (PAC)
- Flights from Houston (HOU) to Panama City (PAC)
- Flights from Istanbul (IST) to Panama City (PAC)
- Flights from Jabalpur (JLR) to Panama City (PAC)
- Flights from La Paz (LAP) to Panama City (PAC)
- Flights from Las Vegas (LAS) to Panama City (PAC)
- Flights from Los Angeles (LAX) to Panama City (PAC)
- Flights from London (LHR) to Panama City (PAC)
- Flights from London (LON) to Panama City (PAC)
- Flights from Medellín (MDE) to Panama City (PAC)
- Flights from Mamfe (MMF) to Panama City (PAC)
- Flights from Nice (NCE) to Panama City (PAC)
- Flights from Newcastle (NCL) to Panama City (PAC)
- Flights from Panama City (PTY) to Panama City (PAC)
- Flights from San Salvador (SAL) to Panama City (PAC)
- Flights from Santo Domingo (SDQ) to Panama City (PAC)
- Flights from San José (SJO) to Panama City (PAC)
- Flights from San Juan (SJU) to Panama City (PAC)
- Flights from Springfield (SPI) to Panama City (PAC)
- Flights from Syracuse (SYR) to Panama City (PAC)
- Flights from Trinidad (TAD) to Panama City (PAC)
- Flights from Tapachula (TAP) to Panama City (PAC)
- Flights from Tampa (TPA) to Panama City (PAC)
- Flights from Tulcan (TUA) to Panama City (PAC)
- Flights from Uberlandia (UDI) to Panama City (PAC)
- Flights from Owen Sound (YOS) to Panama City (PAC)
- Flights from Zürich (ZRH) to Panama City (PAC)
- Albrook Shopping Mall
- Calidonia Holidays
- Cinta Costera
- Metropolitan Cathedral of Panama
- Metropolitan Nature Park
- Pacific Center
- Palacio Bolivar
- Visit Bella Vista
- Visit Bethania
- Visit Calidonia
- Visit Campo Alegre
- Visit Curundu
- Visit El Cangrejo
- Visit Marbella
- Visit Obarrio
- Visit Punta Pacifica
- Visit Punta Paitilla
- Visit Santa Ana