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Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Keys.
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Big Pine Key, FL
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Keys

Experience the relaxing area of Lower Keys—bars, boating and sights from Florida Keys Beaches to Sugarloaf Beach.

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Big Pine Key showing a bay or harbour, a coastal town and general coastal views

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lower Keys?
How much you pay for a 5-star hotel in Lower Keys can vary based on when you want to travel and how long you plan to be away, among a number of factors. Use our price per night filter and other search tools to score the best rate on a luxurious getaway.

  • Search for the lowest price per night

What makes a hotel 5 stars in Lower Keys?
Exceptional guest service is the foundation of every 5-star hotel in Lower Keys. From the second you arrive, staff are at your beck and call, whether arranging valet parking or providing in-room massages. Plus, hotels must feature top-rate amenities to qualify for a 5-star rating. These can include luxury bath products, an on-site spa, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Lower Keys?
Our filters are the best way to find exactly what you want. Select "All inclusive" and "5-star" to see the most luxurious resorts in Lower Keys where your meals, accommodation, activities and entertainment are included in the upfront price. At these getaways, your holiday is pure indulgence from the moment you pull up to the entrance.