Title: TOP Lower Keys Spa Hotels for 2026 - Spas in Lower Keys, FL | Expedia.co.uk [Lower Keys Travel Guide](https://expedia.co.uk/Lower-Keys.dx553248621593965863)[Hotels in Lower Keys](https://expedia.co.uk/Lower-Keys-Hotels.d553248621593965863.Travel-Guide-Hotels)[Holiday Rentals in Lower Keys](https://expedia.co.uk/Lower-Keys-Holiday-Rentals.d553248621593965863.Travel-Guide-HolidayRentals)[Flights to Lower Keys](https://expedia.co.uk/Cheap-Flights-To-Lower-Keys.d553248621593965863.Travel-Guide-Flights)[Things to do in Lower Keys](https://expedia.co.uk/Things-To-Do-In-Lower-Keys.d553248621593965863.Travel-Guide-Activities)[Lower Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lower-Keys.d553248621593965863.Car-Hire-Guide)[Lower Keys Holidays](https://expedia.co.uk/Lower-Keys.d553248621593965863.Holidays-City-Breaks) ![Sunsets in the Florida Keys are hard to beat! #floridakeys #bahiahonda](https://images.trvl-media.com/place/630134272121270272/9d317313-854c-45d6-9856-bbff8fbe386a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jen - Nealys On Wheels ![](https://images.trvl-media.com/place/630134272121270272/9d317313-854c-45d6-9856-bbff8fbe386a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Lower Keys Spa Hotels Tonight [5 Mar - 6 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965863&startDate=2026-03-05&endDate=2026-03-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Mar - 7 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965863&startDate=2026-03-06&endDate=2026-03-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965863&startDate=2026-03-06&endDate=2026-03-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248621593965863&startDate=2026-03-13&endDate=2026-03-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lower Keys hotels with a spa ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c73d9fc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c028e7a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, sea views ](https://images.trvl-media.com/lodging/1000000/10000/1000/901/cd7c9771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Ocean View | Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1000/901/c6f4724b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Centric Key West Resort and Spa [](https://www.expedia.co.uk/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) Key West Historic District 9.0/10 Wonderful (1,002 reviews) - Luxurious oceanfront escape with 3 spa treatment rooms offers deep-tissue massages, facials, and holistic therapies for pure rejuvenation. £352 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Key-West-Hotels-Hyatt-Centric-Key-West-Resort-And-Spa.h901.Hotel-Information) ![3 outdoor pools, pool loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/854776a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/92bf29ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/9ad49064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/c4d130ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquility Bay Beachfront Hotel and Resort [](https://www.expedia.co.uk/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) Marathon 8.8/10 Excellent (1,003 reviews) - Rejuvenate your spirit at this waterfront sanctuary where serene spa treatments complement 3 sparkling pools. £385 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![Outdoor treatment area, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/6f2bdc21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/48229e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/123aeac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/460000/457900/457821/dc04826f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reach Key West, Curio Collection by Hilton [](https://www.expedia.co.uk/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information) Old Town Key West 8.6/10 Excellent (1,008 reviews) - Luxurious beachfront spa retreat offers deep-tissue massages and serene outdoor treatments in Key West. £491 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Key-West-Hotels-The-Reach-Key-West.h457821.Hotel-Information) ![Couples treatment room(s), body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/8f5721fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/1b169515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/bd916166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/7df2a82d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Marina Key West, Curio Collection by Hilton [](https://www.expedia.co.uk/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) Old Town Key West 8.4/10 Very good (563 reviews) - Beach resort with spa offering aromatherapy, Ayurvedic treatments, and beachside massages for ultimate relaxation. £504 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) ![Sports facility](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/8e0c148b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Steam room, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/13c72c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/0e78e180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/71d566a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Faro Blanco Resort Marathon Florida Keys, Curio by Hilton [](https://www.expedia.co.uk/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) Marathon 8.8/10 Excellent (1,215 reviews) - Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialised massages in serene rooms. £323 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) ![Couples treatment room(s), facials, massages](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/546caf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/1441613f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/3bfd19eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/70df70cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southernmost Beach Resort and Guesthouses [](https://www.expedia.co.uk/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) Old Town Key West 8.8/10 Excellent (3,109 reviews) - Serene beachside spa oasis offers tropical relaxation with ocean views and couples treatments. £421 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) ![Body treatments, aromatherapy, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/7a4ee33e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/a299c4a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/05980c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/16700/16682/048e43bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ocean Key Resort - A Noble House Resort [](https://www.expedia.co.uk/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information) Key West Historic District 9.2/10 Wonderful (1,004 reviews) - Waterfront resort spa with exotic massage options and ocean views offers full-service relaxation by the Key West sunset. £615 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Key-West-Hotels-Ocean-Key-Resort-A-Noble-House-Resort.h16682.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/f5ff754a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/d58c67cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/c0cbada1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Dockside) | Living room | 42-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/053d9529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pier House Resort & Spa [](https://www.expedia.co.uk/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information) Key West Historic District 9.0/10 Wonderful (1,052 reviews) - Waterfront spa resort invites relaxation with private beach, outdoor pool, and rejuvenating treatments in Key West's central locale. [](https://www.expedia.co.uk/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/4d671ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/360a1c60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/841e73b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17450000/17442800/17442701/79d1c8de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Opal Key Resort & Marina, Key West [](https://www.expedia.co.uk/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information) Old Town Key West 9.2/10 Wonderful (1,065 reviews) - Indulge in oceanfront spa retreats with sunset views at this tropical Key West haven just steps from Duval Street. £470 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Key-West-Hotels-Opal-Key-Resort-Marina.h17442701.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/1ac57c41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/5a054f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/9f64224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/02a3a50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa [](https://www.expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Marathon 9.2/10 Wonderful (1,099 reviews) - Restore serenity at this beachfront hotel with 5 tranquil spa treatment rooms and multiple outdoor pools overlooking stunning ocean views. £449 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20®ionId=553248621593965863&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Lower Keys Pool Breakfast included Hot tub 4 stars 5 stars ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_553248621593965863) ## Top Lower Keys Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Luxury Hotels in Bahia Honda Key ](https://www.expedia.co.uk/Bahia-Honda-Key-Hotels-Luxury-Hotel.0-0-d553248635083902001-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Big Pine Key ](https://www.expedia.co.uk/Big-Pine-Key-Hotels-Budget-Hotels.0-0-d7195-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Big Pine Key Hotels ](https://www.expedia.co.uk/Big-Pine-Key-Hotels.d7195.Travel-Guide-Hotels) - [Caravan Parks in Big Torch Key ](https://www.expedia.co.uk/Big-Torch-Key-Caravan-Parks.d553248635974614531-aaCaravanParks.Travel-Guide-Accommodation) - [Big Torch Key Hotels ](https://www.expedia.co.uk/Big-Torch-Key-Hotels.d553248635974614531.Travel-Guide-Hotels) - [Cheap Hotels in Boca Chica Key ](https://www.expedia.co.uk/Boca-Chica-Key-Hotels-Budget-Hotels.0-0-d553248635083916609-tBudgetHotels.Travel-Guide-Filter-Hotels) - 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