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17 Aug - 18 Aug
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18 Aug - 19 Aug
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21 Aug - 23 Aug
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28 Aug - 30 Aug

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Our top choices for Looe Key National Marine Sanctuary hotels

1. Beachside Resort & Residences

Beachside Resort & Residences
21.9 mi from Looe Key National Marine Sanctuary
United States
Nicole
£159
includes taxes & fees
30 Aug - 31 Aug
Beachside Resort & Residences

2. Blue Flamingo Resort Key West

Blue Flamingo Resort Key West
22 mi from Looe Key National Marine Sanctuary
United States
Robert
£138
includes taxes & fees
1 Sept - 2 Sept
Blue Flamingo Resort Key West

3. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
24.5 mi from Looe Key National Marine Sanctuary
United States
Robert
£169
includes taxes & fees
1 Sept - 2 Sept
Southernmost Beach Resort and Guesthouses

4. Margaritaville Beach House Key West

Margaritaville Beach House Key West
23 mi from Looe Key National Marine Sanctuary
United States
Raphael
£194
includes taxes & fees
30 Aug - 31 Aug
Margaritaville Beach House Key West

5. Hyatt Vacation Club at Windward Pointe, Key West

Hyatt Vacation Club at Windward Pointe, Key West
21.7 mi from Looe Key National Marine Sanctuary
United States
Mukunda
£176
includes taxes & fees
31 Aug - 1 Sept
Hyatt Vacation Club at Windward Pointe, Key West

6. Havana Cabana at Key West

Havana Cabana at Key West
22.4 mi from Looe Key National Marine Sanctuary
United Kingdom
Fabrizio
£167
includes taxes & fees
1 Sept - 2 Sept
Havana Cabana at Key West

7. Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
24.2 mi from Looe Key National Marine Sanctuary
United States
Dirk
£229
includes taxes & fees
14 Sept - 15 Sept
Casa Marina Key West, Curio Collection by Hilton

8. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
21 mi from Looe Key National Marine Sanctuary
United States
Idania
£220
includes taxes & fees
26 Aug - 27 Aug
Isla Bella Beach Resort & Spa

9. Hyatt Vacation Club at Beach House, Key West

Hyatt Vacation Club at Beach House, Key West
21.7 mi from Looe Key National Marine Sanctuary
United States
Lakshit
£177
includes taxes & fees
1 Sept - 2 Sept
Hyatt Vacation Club at Beach House, Key West

10. Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection
21.9 mi from Looe Key National Marine Sanctuary
United Kingdom
lee
£119
includes taxes & fees
31 Aug - 1 Sept
Hilton Garden Inn Key West / The Keys Collection

11. Parmer's Resort

Parmer's Resort
8.7 mi from Looe Key National Marine Sanctuary
United States
John
£101
includes taxes & fees
18 Aug - 19 Aug
Parmer's Resort

12. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
24.4 mi from Looe Key National Marine Sanctuary
United States
Andrea
£180
includes taxes & fees
3 Sept - 4 Sept
The Reach Key West, Curio Collection by Hilton

13. DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West
21.7 mi from Looe Key National Marine Sanctuary
United States
Jose
£126
includes taxes & fees
7 Sept - 8 Sept
DoubleTree Resort by Hilton Grand Key - Key West

14. Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
23.1 mi from Looe Key National Marine Sanctuary
United States
Netanel
£159
includes taxes & fees
30 Aug - 31 Aug
Parrot Key Hotel & Villas

15. Pier House Resort & Spa

Pier House Resort & Spa
25.2 mi from Looe Key National Marine Sanctuary
United States
Cynthia
£200
includes taxes & fees
23 Aug - 24 Aug
Pier House Resort & Spa

16. Hilton Key West Resort & Marina

Hilton Key West Resort & Marina
20.3 mi from Looe Key National Marine Sanctuary
United States
Linda
£166
includes taxes & fees
1 Sept - 2 Sept
Hilton Key West Resort & Marina

17. The Perry Hotel & Marina Key West

The Perry Hotel & Marina Key West
21 mi from Looe Key National Marine Sanctuary
United States
Mauricio
£156
includes taxes & fees
19 Aug - 20 Aug
The Perry Hotel & Marina Key West

18. The Laureate Key West

The Laureate Key West
22.3 mi from Looe Key National Marine Sanctuary
United States
Jayce
£153
includes taxes & fees
18 Aug - 19 Aug
The Laureate Key West

19. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
22.3 mi from Looe Key National Marine Sanctuary
United States
Barbara
£220
includes taxes & fees
13 Sept - 14 Sept
Tranquility Bay Beachfront Hotel and Resort

20. Hampton Inn Key West FL

Hampton Inn Key West FL
21.6 mi from Looe Key National Marine Sanctuary
United States
Shelly
£98
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Key West FL
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Compare popular hotels close to Looe Key National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Parmer's Resort
9.0
Wonderful
1,004 reviews
View
Karaoke room
Looe Key Reef Resort
7.6
Good
1,002 reviews
View
Exterior
Sugar Loaf Lodge
8.2
Very good
1,001 reviews
View
1 Bedroom Aqualodge # 6 Tarpon | Living area | Flat-screen TV
Old Wooden Bridge Resort and Marina
8.6
Excellent
366 reviews
View
Exterior
Atlantic View Luxury Villa with Pool
7.4
Good
3 reviews
View

Top Looe Key National Marine Sanctuary Hotel Reviews

Star Room Barnacle Resort

Star Room Barnacle Resort

10/10 Excellent
"Great work!"
Tom L. 1-night trip
Posted 12 hours ago
Star Room Barnacle Resort
Looe Key Reef Resort

Looe Key Reef Resort

10/10 Excellent
"Great clean place to stay with a great tiki bar/restaurant/pool and fabulous dive/snorkle center on site with a fabulous crew that takes you to the protected Looe Key Reef. Highly recommend the water trip over anything in Key West,"
Bonita 4-night trip
Posted 23 hours ago
Looe Key Reef Resort
Parmer's Resort

Parmer's Resort

8/10 Good
"Property was clean, well-kept, easily accessible with lots of accommodations to choose from: hammocks, kayaks, docks, pool, star-gazing. Though kayaks were only available until 3pm - that seemed way too early to stop enjoying the water. All in all though, we would come back, just better prepared with timing to actually enjoy the water better."
Erin 3-night trip
Posted 3 days ago
Parmer's Resort
Deep/Wide/Flow-Though Canal, 1st Canal From Open Water, No Hwy 1 Road Noise

Deep/Wide/Flow-Though Canal, 1st Canal From Open Water, No Hwy 1 Road Noise

10/10 Excellent
"1"
Joe J. 29-night trip
Posted 2 weeks ago
Deep/Wide/Flow-Though Canal, 1st Canal From Open Water, No Hwy 1 Road Noise
One of the very few beach houses with a daily, rental license in the Keys.

One of the very few beach houses with a daily, rental license in the Keys.

10/10 Excellent
"The house is right on the water with spectacular views. It accommodated 11 of us perfectly for 5 nights (6 adults & 5 kids). We brought a pontoon boat & were able to dock it at the end of the dock. We found spectacular snorkeling off of Looe Key. The kids loved the pool, paddle boarding & kayaking (we brought our own). The house is very clean & the bathrooms & kitchen were modern & nice. We thoroughly enjoyed Pops BBQ, & Tacos Express (both were the BEST food). The host Mariana communicated super fast with us & facilitated check in. Loved the whole experience & would definitely do it again!!"
Lori F. 5-night trip
Posted 2 months ago
One of the very few beach houses with a daily, rental license in the Keys.
Sirena Key | Luxury Oceanfront Estate, Pool, Guest Cottage, Dock, 30min to Key West

Sirena Key | Luxury Oceanfront Estate, Pool, Guest Cottage, Dock, 30min to Key West

10/10 Excellent
"We had an incredible month-long stay at Sirena Key. The property is 5 stars all the way, from the stunning ocean views over the sunken in-ground pool, to the luxurious primary suite. Examples of incredible attention to detail include a kitchen fully stocked with utensils and serve ware, more than adequate number of bath/pool towels, and an array of outdoor toys like kayaks and paddle boards. The property management team was attentive to our inquires, which we appreciated as we were staying at the home with two small children. We left Sirena Key with beautiful family memories. Highly recommend!"
Steve M. 28-night trip
Posted 2 months ago
Sirena Key | Luxury Oceanfront Estate, Pool, Guest Cottage, Dock, 30min to Key West
Beautiful 2/2 Waterfront Designer Home for your family vacation

Beautiful 2/2 Waterfront Designer Home for your family vacation

10/10 Excellent
" Nice house, beautifully decorated and clean. Great location for boating. We brought our 24’ boat, total length is 27.5’ with windlass, anchor and motor up. The neighbor is so kind and didn’t mind that our boat was encroaching on his seawall."
Jennifer S. 29-night trip
Posted 4 months ago
Beautiful 2/2 Waterfront Designer Home for your family vacation
Beachfront 3B/3B Fishing Oasis

Beachfront 3B/3B Fishing Oasis

10/10 Excellent
"This house was exactly how we like to vacation. The property is cozy with a laid-back easy-living vibe. Perfect place to launch your kayaks, then lounge in the pool afterwards. Great water views with no mangroves to interrupt it.The kitchen was fully stocked with all the dishes, pots/pans, and appliances you could need. Gas grill downstairs. I did try out the pizza oven, but it was just too windy for it to be effective.There are many very good Cuban restaurants nearby. 8 minutes to Big Pine where you’ll find more restaurants, shops, and Winn-Dixie for groceries. 30 miles into Key West if you feel the need to be a tourist.Definitely want to return for another stay if the property (which is for sale) remains on the vacation rental market.We stayed for a month in April and the temperatures were perfect."
Annette D. 29-night trip
Posted 4 months ago
Beachfront 3B/3B Fishing Oasis
Treehouse Private Village Barnacle Resort

Treehouse Private Village Barnacle Resort

10/10 Excellent
"Barnacle Resort Stayed 3 nights at the “Treehouse Private Village” in the Barnacle Resort on Big Pine Key. I really enjoyed my stay, the property is quite nice, and very private. One of the attractions on Big Pine Key is seeing Key deer, which astonishingly wandered around the resort property several times a day. Don’t touch or feed them, very illegal, but you can get quite close, as they are fairly tame.It wasn’t clear when I made my reservation just where the room was on the property, since the pictures mainly showed the larger building. As it turns out, my reservation was for the separate, smaller building next to the main house. The “Treehouse” was completely private, and has its own kitchen and full bath, which I really appreciated. There are three or four available rooms in the main building, along with the common areas for dining, etc. So be sure you have the correct room information when you book your stay.There were a couple of things I had to deal with, like the TV wasn’t plugged in, no power outlets in the kitchen for the coffee machine (ran it off the floor in the main room), but really nothing major. And the host responded quickly to any questions, plus I think there’s folks onsite for anything that might be needed.All in all, I was quite pleased with my experience there. If natural beauty, privacy, and location close to Bahia Honda State Park and Key West are at the top of your list, check this place out."
Paul L. 3-night trip
Posted 4 months ago
Treehouse Private Village Barnacle Resort

Other attractions near Looe Key National Marine Sanctuary

Munson Island

Commune with nature and explore the great outdoors at Munson Island during your travels in Big Pine Key. While you're in the area, stroll along the beaches.
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Big Munson Island

Commune with nature and explore the great outdoors at Big Munson Island during your travels in Big Pine Key. While you're in the area, stroll along the beaches.
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Newfound Harbor Keys

Commune with nature and explore the great outdoors at Newfound Harbor Keys during your travels in Big Pine Key. While you're in the area, wander around the natural setting.
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Hopkins Island

Commune with nature and explore the great outdoors at Hopkins Island during your travels in Big Pine Key. While you're in the area, wander around the natural setting.
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Cook Island

9.2/10 (5 reviews)
Commune with nature and explore the great outdoors at Cook Island during your travels in Big Pine Key. While you're in the area, wander around the natural setting.
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Pye Key

Commune with nature and explore the great outdoors at Pye Key during your travels in Summerland Key.
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Coupon Bight Aquatic Preserve

Commune with nature and explore the great outdoors at Coupon Bight Aquatic Preserve during your travels in Big Pine Key. While in this relaxing area, you can enjoy the restaurants.
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Frequently asked questions

What's the area like around Looe Key National Marine Sanctuary?
Looe Key National Marine Sanctuary is located in an area that travellers like for its local tours. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Looe Key National Marine Sanctuary?
Located 8.2 mi (13.2 km) from Looe Key National Marine Sanctuary, Parmer's Resort is one of the top choices for your stay based on our traveller data.
If I need to cancel the hotel reservation for my stay near Looe Key National Marine Sanctuary, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best options available near Looe Key National Marine Sanctuary.

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