Title: The Best Hotels Closest to Looe Key National Marine Sanctuary in - 2025 Updated Prices | Expedia.co.uk [United States of America Travel Guide](https://expedia.co.uk/United-States-Of-America.dx201)[Holiday Rentals in United States of America](https://expedia.co.uk/Destinations-In-United-States-Of-America.d201.Holiday-Rental-Destinations)[Flights to United States of America](https://expedia.co.uk/Destinations-In-United-States-Of-America.d201.Flight-Destinations)[Looe Key National Marine Sanctuary Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Looe-Key-National-Marine-Sanctuary.d553248621533115813.Car-Hire-Guide)[Looe Key National Marine Sanctuary Holidays](https://expedia.co.uk/Looe-Key-National-Marine-Sanctuary-United-States-Of-America.d553248621533115813.Attraction) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels Near Looe Key National Marine Sanctuary, ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [30 Sept - 1 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621533115813&startDate=2025-09-30&endDate=2025-10-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Oct - 2 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621533115813&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621533115813&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248621533115813&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Looe Key National Marine Sanctuary ![Suite, 1 Bedroom, Kitchen, Sea Facing | Beach/ocean view](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/0a8ded52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/a69616f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/9585f19f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parmer's Resort 8.7 mi from Looe Key National Marine Sanctuary 9.0/10 Wonderful (1002) "Had a wonderful time place is very nice enjoyed ourselves " £114 includes taxes & fees 1 Oct - 2 Oct [](https://www.expedia.co.uk/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Flat-screen TV](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/048a25f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/71a41b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/w6000h3995x0y5-7c6df35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/47e5cd0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barnacle Resort 7 mi from Looe Key National Marine Sanctuary 8.2/10 Very good (40) "Perfect place for a quiet getaway." [](https://www.expedia.co.uk/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/50f5ab62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Townhome | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/f6c4f83d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Toaster](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/c9f2ce52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, pool loungers](https://images.trvl-media.com/lodging/90000000/89720000/89711600/89711513/ce9353ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Torch Cottages 8.3 mi from Looe Key National Marine Sanctuary 9.2/10 Wonderful (9) "Felt like home. We'd stay here again!" [](https://www.expedia.co.uk/Little-Torch-Key-Hotels-Little-Torch-Cottages.h89711513.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/9eff678c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/974f08a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Queen Beds | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/13570c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Looe Key Reef Resort 7.8 mi from Looe Key National Marine Sanctuary 7.4/10 Good (1004) "We only stayed one night but it was nice and we enjoyed ourselves." £167 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![2 Bedroom Aqua Lodge # 13 Barracuda | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/92962431.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/1bf38821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 Bedroom Aqualodge # 6 Tarpon | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/dee083de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:30 AM to 8:00 PM, pool loungers](https://images.trvl-media.com/lodging/18000000/17110000/17102400/17102343/bdbf7145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Wooden Bridge Resort and Marina 10.9 mi from Looe Key National Marine Sanctuary 8.6/10 Excellent (258) "Really I have the best experience and soon I want to go again " £164 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Big-Pine-Key-Hotels-Old-Wooden-Bridge-Marina.h17102343.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/95d2903e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/a0504154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/125c52d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/4000000/3920000/3918200/3918121/a36bdda4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sugar Loaf Lodge 12.1 mi from Looe Key National Marine Sanctuary 8.2/10 Very good (1005) "Nice family owned spot. " £83 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sugarloaf-Key-Hotels-Sugar-Loaf-Lodge.h3918121.Hotel-Information) ![Swim-up bar](https://images.trvl-media.com/lodging/112000000/111540000/111535500/111535402/17e19347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/112000000/111540000/111535500/111535402/6f8ffa24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/112000000/111540000/111535500/111535402/f6f802a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Villa, Ocean View | Private kitchenette](https://images.trvl-media.com/lodging/112000000/111540000/111535500/111535402/c0b097db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Atlantic View Luxury Villa with Pool 10 mi from Looe Key National Marine Sanctuary 10/10 Exceptional (1) "We were here for a night and it was great. A nice rustic feel on a big property, with good view. " [](https://www.expedia.co.uk/Summerland-Key-Hotels-Atlantic-View-Luxury-Villa-With-Pool.h111535402.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-14&endDate=2025-10-15®ionId=553248621533115813&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLooe-Key-National-Marine-Sanctuary-Hotels.0-l553248621533115813-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLooe-Key-National-Marine-Sanctuary-Hotels.0-l553248621533115813-0.Travel-Guide-Filter-Hotels) ## Top Looe Key National Marine Sanctuary Hotel Reviews ![Star Room Barnacle Resort](//images.trvl-media.com/lodging/112000000/111160000/111152500/111152457/9bf80e17_y.jpg) ### Star Room Barnacle Resort 10/10 Excellent "We loved the location - quiet and secluded - away from everything but not so far away that you felt isolated. All very clean and amenities were as described." [](https://expedia.co.uk/Big-Pine-Key-Hotels-Star-Room-Barnacle-Bnb.h111152457.Hotel-Information) ![Looe Key Reef Resort](//images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01_y.jpg) ### Looe Key Reef Resort 8/10 Good "This is a very REASONABLY priced lodging for the FL Keys so expect simple things. We had a great stay, room was clean, the young gent at the front desk was exceptionally friendly and helpful, ditto at checkout. The beds are comfortable. The shower head had great pressure and the onsite tiki bar is a big plus. There were no plastic cups or coffee maker in the room but there was a microwave and fridge and table with two chairs. The ice machine was not working but there is a quickie mart just next door for that if you needed it. Could the resort be flashier, yes it could but Looe Key Reef Resort offered us a cost effective comfy safe stay in a place where time in the room was not important. We did not use the pool or the dive/snorkle amenities as we came down to fish, but if you wanted that stuff it’s all here. We hope to be back soon." [](https://expedia.co.uk/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![Parmer's Resort](//images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a_y.jpg) ### Parmer's Resort 10/10 Excellent "Clean room , many options for guests to do around property. Close to key west and marathon" [](https://expedia.co.uk/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Treehouse Private Village Barnacle Resort](//images.trvl-media.com/lodging/112000000/111160000/111152500/111152459/d1e84791_y.jpg) ### Treehouse Private Village Barnacle Resort 8/10 Good "Great location, quiet with great views!" [](https://expedia.co.uk/Big-Pine-Key-Hotels-Treehouse-Private-Village.h111152459.Hotel-Information) ![Barnacle Resort](//images.trvl-media.com/lodging/91000000/90990000/90989500/90989471/048a25f3_y.jpg) ### Barnacle Resort 10/10 Excellent "No communication when I couldn’t get into my room. Horrible situation. DO NOT STAY AT THIS PROPERTY!! Total scam. " [](https://expedia.co.uk/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) ![Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool](//images.trvl-media.com/lodging/100000000/99110000/99102300/99102202/5cf3f655_y.jpg) ### Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool 10/10 Excellent "This property is making it to the top of our favorites! The view is the best. Very distracting when needing to work. The property was clean, everything worked, had everything we needed, the neighborhood was nice and quiet. Took full advantage of the kayaks and loved all the sea life we encountered. Lots of young sharks, sawfish, turtles, rays, sea slugs, crabs etc up in the shallows . Snorkeling right in front of the house, even tried our hand at lobster tickling. We brought jet skis and the marina down the road was convenient for putting in and out for some day trips. Convenient to drive to Key West to pick up the kids from the airport or to make an afternoon trip to Key West or Marathon, but loved the slower pace of the keys in between. Lots of restaurants to try out. Only disappointing thing is we have to leave. " [](https://expedia.co.uk/Big-Pine-Key-Hotels-Keys-To-The-Kingdom-Private-Oceanfront-Retreat-With-Beach-And-Pool.h99102202.Hotel-Information) ### Destinations near [](https://expedia.co.uk/National-Key-Deer-Refuge-Visitor-Center-Hotels.0-l553248635974766232-0.Travel-Guide-Filter-Hotels) #### National Key Deer Refuge Visitor Center National Key Deer Refuge Visitor Center is just one of the places to see in Big Pine Key, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the beaches. [See properties](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635974766232) ## Frequently asked questions ### What's the area like around Looe Key National Marine Sanctuary? > Looe Key National Marine Sanctuary is located in an area that travellers like for its local tours. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area. ### What's the best hotel to stay close to Looe Key National Marine Sanctuary? > [Barnacle Resort](https://www.expedia.co.uk/Big-Pine-Key-Hotels-Barnacle-Bed-And-Breakfast.h90989471.Hotel-Information) is one of the top choices for your stay based on our traveller data, and this B&B offers free parking and a rooftop terrace. You'll find it 7 mi (11.3 km) from Looe Key National Marine Sanctuary. Other good choices around the area include [Looe Key Reef Resort](https://www.expedia.co.uk/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) and [Parmer's Resort](https://www.expedia.co.uk/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information). ### If I need to cancel the hotel reservation for my stay near Looe Key National Marine Sanctuary, will I receive a refund? > Yes! Most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. 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