Compare and book 4 Star hotels in Central San Diego, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Central San Diego 4 Star Hotels
Our top choices for Central San Diego 4-star hotels
DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission ValleyMission Valley
8.4 out of 10, Very good, (1,548 reviews)
"Clean and great staff "
Peter
The price is £115
includes taxes & fees
8 Mar - 9 Mar
8.0 out of 10, Very good, (2,338 reviews)
"The cleanest room and nicest staff honestly would stay here again"
Kevin
The price is £111
includes taxes & fees
2 Mar - 3 Mar
9.2 out of 10, Wonderful, (2,939 reviews)
"Excellent facilities and location "
Felix
9.2 out of 10, Wonderful, (1,498 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
Holly
The price is £194
includes taxes & fees
2 Mar - 3 Mar
8.6 out of 10, Excellent, (1,730 reviews)
"Great stay!"
Linda
The price is £115
includes taxes & fees
8 Mar - 9 Mar
Embassy Suites by Hilton San Diego La Jolla
Embassy Suites by Hilton San Diego La JollaUniversity City
8.8 out of 10, Excellent, (1,868 reviews)
"Great included breakfast!"
Gina
The price is £162
includes taxes & fees
6 Mar - 7 Mar
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was very accommodating "
Paolo
The price is £123
includes taxes & fees
8 Mar - 9 Mar
8.8 out of 10, Excellent, (1,003 reviews)
"Really clean room, comfortable towels, would definitely come back!"
Samuel
The price is £167
includes taxes & fees
22 Mar - 23 Mar
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Central San Diego
Explore the seaside area of Central San Diego—beaches, sports teams and popular sights like San Diego Zoo.
Top Central San Diego Hotel Reviews
DoubleTree by Hilton Hotel San Diego - Mission Valley
10/10 Excellent
Find out more about Central San Diego
Frequently asked questions
Explore a world of travel with Expedia
- 2 Star Hotels in San Diego Coast
- 3 Star Hotels in Catalina Island
- 3 Star Hotels in Gaslamp Quarter
- 3 Star Hotels in Golden Hill
- 3 Star Hotels in North Central San Diego
- 3 Star Hotels in Point Loma
- 3 Star Hotels in San Diego
- 3 Star Hotels in Sorrento Valley
- 4 Star Hotels in Carlsbad
- 4 Star Hotels in Coronado
- 4 Star Hotels in Gaslamp Quarter
- 4 Star Hotels in La Jolla
- 4 Star Hotels in Oceanside
- 4 Star Hotels in Rancho Bernardo
- 4 Star Hotels in San Diego Coast
- 4 Star Hotels in San Diego
- 4 Star Hotels in Temecula Valley Wine Country
- 5 Star Hotels in Carlsbad
- 5 Star Hotels in Catalina Island
- 5 Star Hotels in Coronado
- 5 Star Hotels in Coronado Island
- 5 Star Hotels in Dana Point
- 5 Star Hotels in La Jolla
- 5 Star Hotels in La Jolla Village
- 5 Star Hotels in Ladera Ranch
- 5 Star Hotels in Laguna Niguel
- 5 Star Hotels in Lake Elsinore
- 5 Star Hotels in Mission Valley
- 5 Star Hotels in Oceanside
- 5 Star Hotels in San Clemente
- 5 Star Hotels in San Diego Coast
- 5 Star Hotels in San Diego
- Birdland Hotels
- Clairemont Mesa East Hotels
- Clairemont Mesa West Hotels
- Marriott Hotels & Resorts in Clairemont
- Clairemont Hotels
- Kearny Mesa Hotels
- Linda Vista Hotels
- Miramar Hotels
- Hotels near Montgomery Field
- Gay-Friendly Hotels in North Clairemont
- Serra Mesa Hotels
- Hotels near Stadium Golf Center & Batting Cages
- University City Hotels
- Flights from Montgomery Field
- Flights from Auckland (AKL) to San Diego (MYF)
- Flights from Alice (ALI) to San Diego (MYF)
- Flights from Amsterdam (AMS) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from Hartford (BDL) to San Diego (MYF)
- Flights from Bishop (BIH) to San Diego (MYF)
- Flights from Upland (CCB) to San Diego (MYF)
- Flights from Chadron (CDR) to San Diego (MYF)
- Flights from Columbus (CMH) to San Diego (MYF)
- Flights from Kiritimati (CXI) to San Diego (MYF)
- Flights from Calexico (CXL) to San Diego (MYF)
- Flights from Douglas (DUG) to San Diego (MYF)
- Flights from El Dorado (ELD) to San Diego (MYF)
- Flights from Fallon (FLX) to San Diego (MYF)
- Flights from Gallup (GUP) to San Diego (MYF)
- Flights from Helsinki (HEL) to San Diego (MYF)
- Flights from Hot Springs (HOT) to San Diego (MYF)
- Flights from Indianapolis (IND) to San Diego (MYF)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Manchester (MAN) to San Diego (MYF)
- Flights from Nacogdoches (OCH) to San Diego (MYF)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Miami (OPF) to San Diego (MYF)
- Flights from Chicago (ORD) to San Diego (MYF)
- Flights from Peoria (PIA) to San Diego (MYF)
- Flights from Pompano Beach (PPM) to San Diego (MYF)
- Flights from Los Angeles (QLA) to San Diego (MYF)
- Flights from Raleigh (RDU) to San Diego (MYF)
- Flights from Reynosa (REX) to San Diego (MYF)
- Flights from Rifle (RIL) to San Diego (MYF)
- Flights from Mariposa (RMY) to San Diego (MYF)
- Flights from Sao Paulo (SAO) to San Diego (MYF)
- Flights from Stockton (SCK) to San Diego (MYF)
- Flights from Spokane (SFF) to San Diego (MYF)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from Salt Lake City (SLC) to San Diego (MYF)
- Flights from Saranac Lake (SLK) to San Diego (MYF)
- Flights from Sacramento (SMF) to San Diego (MYF)
- Flights from Sydney (SYD) to San Diego (MYF)
- Flights from Santa Paula (SZP) to San Diego (MYF)
- Flights from Tacoma (TIW) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Troutdale (TTD) to San Diego (MYF)
- Flights from Concord (USA) to San Diego (MYF)
- Flights from Québec (YQB) to San Diego (MYF)
- Flights from Yuma (YUM) to San Diego (MYF)
- Flights from Vancouver (YVR) to San Diego (MYF)
- Flights from Toronto (YYZ) to San Diego (MYF)