A red train on tracks, palm trees, and modern buildings.

Compare and book 4 Star hotels in Central San Diego, San Diego

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Check availability on Central San Diego 4 Star Hotels

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Central San Diego 4-star hotels

An outdoor lounge area with seating, a fire feature, and a pool in the background.
A stone wall with a neon sign that reads "Tom & Jerry."
A modern restaurant with multiple seating areas, including booths and tables. There are hanging lights and a variety of plants.
A spacious lobby with a bar area, leather armchairs, and a reception desk.

1. Town and Country San Diego

Town and Country San Diego
Mission Valley
United States
Nelly
£185
includes taxes & fees
10 Nov - 11 Nov
Town and Country San Diego
A bar area with a glass ceiling, a central bar counter, and multiple stools.
A dimly lit room with patterned walls, a wooden table, and a chair.
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.
A checkered floor with round tables and chairs, a patterned ceiling, and large windows.

2. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
United States
katie
£237
includes taxes & fees
12 Nov - 13 Nov
Lafayette Hotel & Club
An outdoor seating area with wicker chairs and a fire pit, surrounded by palm trees and string lights.
A spacious lobby with a central seating area, a staircase, and a view of the hallway leading to the entrance.
A grand lobby with a marble floor, a central table with floral arrangements, a staircase, and potted plants.
A modern dining area with a large table, chairs, and hanging plants.

3. DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
Mission Valley
United States
Alesi
£125
includes taxes & fees
8 Nov - 9 Nov
DoubleTree by Hilton Hotel San Diego - Mission Valley
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A spacious indoor lounge area with a central fire feature, multiple seating arrangements, and a bar area.
A hotel entrance with a covered outdoor seating area, palm trees, and a car parked in front.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a tall building in the background.

4. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
£161
includes taxes & fees
6 Nov - 7 Nov
San Diego Marriott La Jolla
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.
A modern lobby with a large window, two sofas, and two black planters with plants.

5. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
United States
Christian
£113
includes taxes & fees
25 Oct - 26 Oct
Hilton San Diego Mission Valley
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.
A swimming pool with a visible water filtration system and a tiled edge.

6. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
£176
includes taxes & fees
30 Oct - 31 Oct
Embassy Suites by Hilton San Diego La Jolla
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A swimming pool with blue lounge chairs and umbrellas, surrounded by a building with balconies.
A pathway leading to a building labeled "LEGACY Hotel."
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.

7. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
United States
christopher
£151
includes taxes & fees
26 Oct - 27 Oct
Legacy Resort Hotel & Spa
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows offering views of the outdoors.
A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a view through an open door.
A hotel room with two beds, a TV, a desk, and a chair.
A modern hotel with a flat roof, large windows, and a sign reading "DOLLYWOOD HOTEL".

8. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
United States
Ramiro
£106
includes taxes & fees
19 Oct - 20 Oct
DoubleTree by Hilton San Diego - Hotel Circle
A swimming pool with lounge chairs and a waterfall feature, surrounded by palm trees and a building with multiple balconies.
A modern hotel with a prominent tower, multiple floors, and a well-lit entrance.
A modern outdoor seating area with a wooden wall, a hanging chair, and a large potted plant.
A modern bar area with a long counter, multiple hanging pendant lights, and a bar stocked with bottles and glasses.

9. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
United States
John
£165
includes taxes & fees
25 Oct - 26 Oct
San Diego Marriott Mission Valley
An outdoor seating area with sofas, a fire pit, and tables covered with blue tablecloths.
A gym with exercise equipment, mirrors, and a wall-mounted TV.
A rooftop swimming pool with sun loungers and umbrellas, surrounded by a landscaped area with trees and a tennis court.
A hotel room with a flat-screen TV, a desk with a chair, a small table with a lamp, a framed picture on the wall, and a large window with curtains.

10. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
United States
lisa
£209
includes taxes & fees
7 Nov - 8 Nov
Hyatt Regency La Jolla
An outdoor patio with tables and chairs, string lights, and umbrellas.
A hotel room with a large bed, a TV, a desk with a chair, and a view of the city through large windows.
Property amenity
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a hilly landscape.

11. Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
Mission Valley
£156
includes taxes & fees
25 Oct - 26 Oct
Sheraton Mission Valley San Diego Hotel
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
An outdoor seating area with sofas and chairs, a wooden staircase, and potted plants.
A modern interior with concrete walls, wooden beams, and a central planter with plants.
A modern bedroom with a large bed, a nightstand, a wall-mounted lamp, and a window with curtains.

12. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
Middletown
United States
Donavin
£124
includes taxes & fees
26 Oct - 27 Oct
City24 Hotel Little Italy Mission Hills
BBQ/picnic Area
Room
Room
Breakfast area

13. Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
Mission Valley
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—beaches, sports teams and popular sights like San Diego Zoo.

See all hotels in Central San Diego
A historic cathedral with intricate architecture, a prominent bell tower, and a blue-domed structure.
Photo by Bilen Z

Top Central San Diego Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

8/10 Good
"Our family stays here every year over the"
Laurie 3-night trip
Posted 17 hours ago
Lafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

10/10 Excellent
"Very nice property"
William 3-night trip
Posted 20 hours ago
Legacy Resort Hotel & Spa

Find out more about Central San Diego

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your holiday in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.
  • Search for the lowest price from £106
What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalised service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodation, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.

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