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Our top choices for Central San Diego holiday rentals

4.5 star property
9.6 out of 10, Exceptional, (127 reviews)
"Very clean, quiet, walking distance to great food"
United States
Amanda
City24 Hotel Little Italy Mission Hills
2.5 star property
8.4 out of 10, Very good, (312 reviews)
"The room was very small but very clean. Great place to stay for the short amount of time we needed it. "
United States
Debra
The price is £84
includes taxes & fees
11 Mar - 12 Mar
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
10.0 out of 10, Exceptional, (48 reviews)
"The home is beautiful, everything was fantastic! The hosts were very helpful and accommodating. The location was convenient and quiet. "
United States
Paulina B.
The price is £187
includes taxes & fees
23 Mar - 24 Mar
Adorable 1 bedroom house 8 min from La Jolla!

Holiday Home in Mid-City

Beautiful Normal Heights Living
10.0 out of 10, Exceptional, (77 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
The price is £234
includes taxes & fees
22 Mar - 23 Mar
Beautiful Normal Heights Living
10.0 out of 10, Exceptional, (271 reviews)
"Convenient and comfortable "
United States
Anya B.
The price is £143
includes taxes & fees
24 Mar - 25 Mar
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
8.0 out of 10, Very good, (2 reviews)
"Wir hatten eine tolle Zeit in San Diego und in der Wohnung. Die Kommunikation mit Rebecca hat super geklappt. Sie hat uns die nötigen Infos für den Check In zur rightigen Zeit gegeben und war während des Aufenthaltes sehr hilfsbereit. Die Wohnung ist für 4 Personen ausreichend groß und perfekt ausgestattet, inkl Waschmaschine und Trockner. Vor allem die Küche haben wir ausgiebig genutzt und haben sehr viel selbst gekocht. Es fehlten lediglich eine Schere und ein Gemüsemesser. Rebecca hat uns...
Germany
Hanna S.
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
9.8 out of 10, Exceptional, (6 reviews)
"It’s within 15 minutes of Riverwalk Golf club and plenty of restaurants. I was very pleased with my stay "
United States
Tyler
The price is £196
includes taxes & fees
3 Apr - 4 Apr
Stylish 1Br Retreat w/Garage AC Close 2 Everything
8.0 out of 10, Very good, (11 reviews)
"Our family stayed for spring break. We found that the location was perfect to be able to get anywhere we needed to go quite conveniently. The house was perfect for what we needed and we were always able to find a parking spot. "
United States
Leah S.
The price is £200
includes taxes & fees
15 Mar - 16 Mar
Cozy Private Home, 10-min From DT, Beach & Parks
9.8 out of 10, Exceptional, (18 reviews)
"My family of four had a wonderful week-long stay here! The apartment was clean, had everything we needed, and we appreciated the secured parking garage. The provided high chair and pack-n-play also worked very well for us. We loved being so close to San Diego's many attractions; it was easy to drive anywhere from this relatively central location. Our host was responsive, helpful, and made sure we had a great stay. We would not hesitate to book this again in the future!"
United States
Benjamin C.
The price is £347
includes taxes & fees
30 Mar - 31 Mar
Artistic + FastWi-Fi + Parking + Pets + EV Charging!
10.0 out of 10, Exceptional, (104 reviews)
"Cute craftsman cottage with great yard and deck for enjoying the outdoors. Host very responsive. We enjoyed our stay in North Park/San Diego."
United States
Lori L.
The price is £336
includes taxes & fees
11 Mar - 12 Mar
Charming Mid-Century Craftsman ~ Hot Tub • Serene Yard
10.0 out of 10, Exceptional, (198 reviews)
"Perfect location for enjoying the city of San Diego. We walked every night in old San Diego. Ten minutes from the beach, ten minutes from the zoo. Here is the big question, would i stay here again? Oh heck yea!!!"
United States
Ted H.
The price is £206
includes taxes & fees
24 Mar - 25 Mar
2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
9.2 out of 10, Wonderful, (57 reviews)
" 100% satisfied. Would stay again if in the area."
United States
Eugene
The price is £242
includes taxes & fees
22 Mar - 23 Mar
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
10.0 out of 10, Exceptional, (14 reviews)
"Absolutely beautiful with very polite and responsive host! Thank you for the stay! "
United States
Krystal T.
The price is £182
includes taxes & fees
18 Mar - 19 Mar
1b1b Central Hillcrest, San Diego condo. Walkable neighborhood and central to SD
9.4 out of 10, Exceptional, (45 reviews)
"This place was well stocked and very inviting. We also enjoyed the design and layout of the property because it allowed for those who wanted to continue the night to do so downstairs while the other who wished to go to bed could find their resting place upstairs. Not to mention the back area that clean and great for keeping the night alive. "
United States
Paris W.
The price is £324
includes taxes & fees
17 Mar - 18 Mar
Cozy 2Bed 1BA Bankers Hill Residence with Parking, no chores!
10.0 out of 10, Exceptional, (33 reviews)
"Great property, very well maintained & the hosts were wonderful. "
United States
Ryan B.
The price is £424
includes taxes & fees
23 Mar - 24 Mar
✔Remote Work✔A/C✔200Mbps✔Kitchen✔Streaming

Holiday Home in Golden Hill

Sunkissed home in Golden Hill San Diego
8.6 out of 10, Excellent, (4 reviews)
"Our stay was absolutely fantastic. This place has everything we needed, and was located in a great location. Hosts were super responsive and helped whenever necessary. Highly highly recommend this stay for anyone looking"
United States
Bryan W.
The price is £344
includes taxes & fees
19 Mar - 20 Mar
Sunkissed home in Golden Hill San Diego
10.0 out of 10, Exceptional, (13 reviews)
"Tiny but clean as a whistle and easy access to Balboa Park and Coronado Island."
United States
Dee Dee S.
The price is £982
includes taxes & fees
6 Apr - 7 Apr
1 mile to Gaslamp—eScooters, Hot tub, Sauna
6.6 out of 10, (11 reviews)
"Me and my girlfriend stayed here for a weekend to kind of just enjoy not having to be home for a weekend and staying here was very nice; the view from the living room and balcony was amazing, was close to all the hotspots in SD and just felt like a second home. I was a bit of a chaotic guest leading up to the check-in and that is because of my work but the host Daniel was very helpful and patient with my mistakes and I appreciate what he did for us."
United States
Nico E.
The price is £304
includes taxes & fees
23 Mar - 24 Mar
2 bed, Just a few Minutes to Airport & Old Town, Great City Skyline Views
8.6 out of 10, Excellent, (12 reviews)
"Love the backyard. Everything was just as described and the stay was easy. Thank you!"
United States
cassie n.
The price is £341
includes taxes & fees
22 Mar - 23 Mar
San Diego Fun: Jacuzzi-Golf-PoolTable-GmRm!
10.0 out of 10, Exceptional, (5 reviews)
"Check in was nice and easy. Hosts were very responsive and helped out with a small supply issue in minutes. The space was clean and organized and made for a great stay on my work trip."
United States
Corey M.
The price is £243
includes taxes & fees
31 Mar - 1 Apr
Explore San Diego from a Central Location with Canyon Views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Central San Diego Hotel Reviews

Find out more about Central San Diego

Everything you need to know about Central San Diego holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Central San Diego holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Central San Diego holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Central San Diego holiday rentals we have selected for you start as low as £84 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Central San Diego rentals

At Expedia, we put the best Central San Diego holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.