Upstate South Carolina Luxury Holidays

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All you need to know about luxury holidays in Upstate South Carolina

What can I expect from a luxury Upstate South Carolina holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in Upstate South Carolina?

Tick the all-inclusive and 5-star filters to find the crème de la crème of Upstate South Carolina holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to Upstate South Carolina?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Upstate South Carolina starting at . Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in Upstate South Carolina?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Upstate South Carolina spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in Upstate South Carolina?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to Upstate South Carolina?

You can wangle a top-notch luxury holiday in Upstate South Carolina for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in Upstate South Carolina with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to Upstate South Carolina with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in Upstate South Carolina to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury Upstate South Carolina Hotels

The Westin Poinsett Greenville

The Westin Poinsett Greenville

120 South Main St Greenville SC
  • 1 hour drive from Clemson University
Stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle and 24-hour room service. Our guests praise the helpful ...
The Westin Poinsett Greenville
Hyatt Regency Greenville

Hyatt Regency Greenville

220 N Main St Greenville SC
  • 1 hour drive from Clemson University
Stay at this business-friendly hotel in Greenville. Enjoy free Wi-Fi, an outdoor pool and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
Hyatt Regency Greenville
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

231 N Pleasantburg Dr Greenville SC
  • 1 hour drive from Clemson University
Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...
8/10 Very good! (1,000 reviews)
"The staff was very helpful and friendly. They were able to answer all of my questions since this was my first time staying there. The breakfast was great! Way more options than I was actually expecting and everything was cooked perfectly."

Reviewed on 10 Aug 2026

Sleep Inn at Greenville Convention Cente
See all 3,050 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Things to do

Greenville: Saturday Morning Breakfast Tour

Greenville: Saturday Morning Breakfast Tour

£68
per adult
Greenville: Saturday Morning Breakfast Tour
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

£26
per adult
Paranormal Walking Tour by Greenville Ghost Tours
Spooky & Haunted Paranormal Bar Crawl Downtown Greenville

Greenville Haunted Bar Tour

£26
per adult
100% of travellers recommend
Greenville Haunted Bar Tour
See all activities in Upstate South Carolina

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.