Missouri Luxury Holidays

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Top flight + Luxury hotel deals in Missouri

Price found within the past 48 hours. Click for updated prices.
River City Casino & Hotel
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All you need to know about luxury holidays in Missouri

What can I expect from a luxury Missouri holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in Missouri?

Tick the all-inclusive and 5-star filters to find the crème de la crème of Missouri holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to Missouri?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Missouri starting at £1,121. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in Missouri?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Missouri spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in Missouri?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to Missouri?

You can wangle a top-notch luxury holiday in Missouri for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in Missouri with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to Missouri with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in Missouri to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury Missouri Hotels

 The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
4.5 out of 5
212 N Kingshighway, St. Louis, MO
  • 8 min drive from Busch Stadium
The price is £192 per night from 27 Jul to 28 Jul
£192
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free Wi-Fi, an outdoor pool and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,002 reviews)
"I recently had the pleasure of staying at the Chase Park Plaza in the Central West End of St. Louis, and as always, it exceeded my expectations! Having stayed here for years, I can confidently say that this hotel is an elegant and rewarding place to stay. The facilities are truly beautiful, combining ..."

Reviewed on 29 Jun 2025

The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
  • 36 min drive from Busch Stadium
The price is £164 per night from 7 Jul to 8 Jul
£164
7 Jul - 8 Jul
includes taxes & fees
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa and 6 restaurants. Our guests praise the clean rooms and the property ...
8.2/10 Very Good! (1,006 reviews)
Quick family trip
"Great stay! Friendly staff, quick check in, quiet rooms."

Reviewed on 2 Jul 2025

Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5 out of 5
100 Carondelet Plaza, St. Louis, MO
  • 14 min drive from Busch Stadium
The price is £494 per night from 13 Jul to 14 Jul
£494
13 Jul - 14 Jul
includes taxes & fees
Stay at this 5-star luxury hotel in St. Louis. Enjoy breakfast (surcharge), room service and a fitness centre. Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (536 reviews)
"Overall, our stay was as wonderful as expected. However, I have to state that I was disappointed in 2 things related to the room itself (1416). While the room overall was nice, the couch near the windows showed extreme wear and tear with torn threading along the seams. Quite disappointing for a purported ..."

Reviewed on 17 Jun 2025

The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.