Title: Southeast Missouri Cheap Holidays 2025/2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southeast Missouri Cheap Holidays ## Book a Cheap Hotel + Flight or Car together to unlock savings Photo by JG Morris Stay added Flight added Car - Economy - Premium economy - Business class - First class Leaving from Going to Dates Travellers ## Room 1 Adults ChildrenAges 2 to 17 InfantsYounger than 2 I only need accommodation for part of my trip - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected ## Top Cheap Southeast Missouri Hotels ![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Motel 6 Poplar Bluff, MO 4101 Highway 67 N, Poplar Bluff, MO - 3 hours drive from Mark Twain National Forest Stay at this motel in Poplar Bluff. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their ... 7.8/10 Good! (1,002 reviews) Everything we needed Reviewed on 19 Oct 2025 [](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn Sikeston 2602 E Malone Avenue, Sikeston, MO - 4 hours drive from Mark Twain National Forest Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ... 9.2/10 Wonderful! (1,005 reviews) Everything was up to par. Enjoyed our stay. Reviewed on 27 Oct 2025 [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) ![Super 8 by Wyndham Farmington](https://images.trvl-media.com/lodging/1000000/860000/855800/855747/d234bb55_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham Farmington 930 Valley Creek Dr, Farmington, MO - 2 hours drive from Mark Twain National Forest Stay at this business-friendly motel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ... 8/10 Very Good! (598 reviews) Good spot…restaurants nearby…plumbing a little noisy in the building. But a nice launch point for visiting central eastern MO parks. Reviewed on 22 Oct 2025 [](https://expedia.co.uk/Farmington-Hotels-Super-8-By-Wyndham-Farmington.h855747.Hotel-Information) [See all 597 properties in Southeast Missouri](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6058763) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## More Holiday Ideas [Flights to Southeast Missouri](https://expedia.co.uk/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Southeast Missouri Hotels](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Southeast Missouri Holiday Rentals](https://expedia.co.uk/Southeast-Missouri-Holiday-Rentals.d6058763.Travel-Guide-HolidayRentals)[Southeast Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Missouri.d6058763.Car-Hire-Guide)[Southeast Missouri Holidays](https://expedia.co.uk/Southeast-Missouri.d6058763.Holidays-City-Breaks)[Things to do in Southeast Missouri](https://expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)