Title: Best Villas in Upstate South Carolina 2026 | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d553248635975748552.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d553248635975748552.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d553248635975748552.Holidays-City-Breaks) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [1 May - 3 May](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [29 May - 31 May](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina villas ![Exterior](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875005/a0afb705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875005/ff9ccba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875005/fec14844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875005/bb77d2f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Band New Luxury Stay, 3 min to Downtown Sleeps 10 [](https://www.expedia.co.uk/Spartanburg-Hotels-Band-New-Luxury-Stay.h115875005.Hotel-Information) Spartanburg 10/10 Exceptional (3 reviews) "Place was great! Felt just like home. Hosts communicated through out to make sure our stay was going smoothly. Would highly recommend.Bob and Lisa L " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bob L. £228 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Band-New-Luxury-Stay.h115875005.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875012/2a760551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875012/8946da72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875012/1aa3f725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115880000/115875100/115875012/e8107634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Stay 2 min to Downtown, King Beds BRAND NEW [](https://www.expedia.co.uk/Spartanburg-Hotels-Luxury-Stay-2-Min-To-Downtown.h115875012.Hotel-Information) Spartanburg 9.4/10 Exceptional (3 reviews) "Beautiful home owner was very responsive. We would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leann v. £228 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Spartanburg-Hotels-Luxury-Stay-2-Min-To-Downtown.h115875012.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/5efbc53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining tables](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/b71e7956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/5c2269e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91910000/91908600/91908503/f2c1860f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Southern Elegance near Downtown Pickens [](https://www.expedia.co.uk/Pickens-Hotels-Grand-Southern-Elegance-Near-Downtown-Pickens.h91908503.Hotel-Information) Pickens £1,376 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Pickens-Hotels-Grand-Southern-Elegance-Near-Downtown-Pickens.h91908503.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120700000/120692600/120692524/62b405be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120700000/120692600/120692524/1e9527b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/121000000/120700000/120692600/120692524/10bf2a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120700000/120692600/120692524/18d71a3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cool villa on private lake with breathtaking views and perfect sunsets [](https://www.expedia.co.uk/Clarkesville-Hotels-Cool-Villa-On-Private-Lake-With-Breathtaking-Views-And-Perfect-Sunsets.h120692524.Hotel-Information) Clarkesville £176 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Clarkesville-Hotels-Cool-Villa-On-Private-Lake-With-Breathtaking-Views-And-Perfect-Sunsets.h120692524.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21®ionId=553248635975748552&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CABIN) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APART_HOTEL) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=COTTAGE) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CONDO) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VILLA) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CHALET) Residences [](https://www.expedia.co.uk/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975748552&latLong=34.711583%2C-82.278231&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=RESIDENCE) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Villas.d553248635975748552-aaVillas.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Villas.d553248635975748552-aaVillas.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. 10/10 Excellent "Services was awesome!" [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Yes" [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Outstanding staff and one of the best free breakfast selections we’ve experienced in a long time. The room was spacious, clean, and comfortable. The fitness center was great too. Everything far exceeded our expectations. We will stay again the next time we’re in Greenville." [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Yes everything and everyone was amazing!" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Room felt clean. Bed and pillows were comfortable. The size of the room was nice and loved having a couch and space for coffee. The included breakfast was way nicer than a normal free hotel breakfast. The staff was very nice. I will definitely stay here again if we are in town. " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![AC Hotel By Marriott Greenville](https://images.trvl-media.com/lodging/59000000/58290000/58282600/58282504/575c54cb_y.jpg) ### AC Hotel By Marriott Greenville 10/10 Excellent "Wonderful staff and clean venue" [](https://expedia.co.uk/Greenville-Spartanburg-Hotels-AC-Hotel-By-Marriott-Greenville.h58282504.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "Clean and great location " [](https://expedia.co.uk/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "The staff was great to us during the ice storm! Lots of places to hang out. " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg) ### Sleep Inn Spartanburg Southwest 10/10 Excellent "Room was very spotless and clean great staff and pet friendly hotel i would recommend anyone to come here 😀 me and my girlfriend had an amazing stay" [](https://expedia.co.uk/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Villas information | Number of reviews | 6 | | ----------------- | -------- | | Accommodation | 7 Villas | | Lowest Price | £228 | | Highest Price | £1,376 | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Anglewood Hotels ](https://www.expedia.co.uk/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Caravan Parks in Duncan ](https://www.expedia.co.uk/Duncan-Caravan-Parks.d6761-aaCaravanParks.Travel-Guide-Accommodation) - 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[Inns in South Carolina ](https://www.expedia.co.uk/South-Carolina-Inns.d242-aaInns.Travel-Guide-Accommodation) - [Lodges in South Carolina ](https://www.expedia.co.uk/South-Carolina-Lodges.d242-aaLodges.Travel-Guide-Accommodation) - [Cabin Rentals in Spartanburg ](https://www.expedia.co.uk/Spartanburg-Cabins.d9787-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Spartanburg ](https://www.expedia.co.uk/Spartanburg-Condos.d9787-aaCondos.Travel-Guide-Accommodation) - [Hotels near Spartanburg Downtown Memorial ](https://www.expedia.co.uk/Spartanburg-Downtown-Memorial-Airport-Hotels.0-aSPA-0.Travel-Guide-Filter-Hotels) - [Spartanburg Historic District Hotels ](https://www.expedia.co.uk/Spartanburg-Historic-District-Hotels.d6288348.Travel-Guide-Hotels) - [Cheap Hotels in Spartanburg ](https://www.expedia.co.uk/Spartanburg-Hotels-Budget-Hotels.0-0-d9787-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Business Hotels in Spartanburg ](https://www.expedia.co.uk/Spartanburg-Hotels-Business-Hotel.0-0-d9787-tBusinessHotel.Travel-Guide-Filter-Hotels) - 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