Hotels in Upstate South Carolina - Best Upstate South Carolina Hotels from £59 - Fully Refundable Options

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Our top choices for Upstate South Carolina hotels

A modern lobby with a reception desk, seating area, and a television screen.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

1. Best Western Spartanburg I-26

Spartanburg

Santhosh

£85

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with sofas, a fire pit, and string lights.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

2. Tru by Hilton Spartanburg

Spartanburg

Anthony

£89

includes taxes & fees

1 Nov - 2 Nov

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

3. Four Points by Sheraton Spartanburg

Spartanburg

John

£90

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A modern kitchen with a central island, bar stools, and pendant lighting.

A reception area with a wooden reception desk, a refrigerator stocked with beverages, and shelves with snacks.

A hotel with a modern design, featuring a prominent entrance and a parking area.

4. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

Joseph

£101

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

5. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Michael

£85

includes taxes & fees

31 Oct - 1 Nov

A modern interior with a fireplace, seating, and a wooden wall.

A modern living room with a flat-screen TV, a brown sofa, a small table, and a blue armchair.

A hotel room with a flat-screen TV, a desk with a chair, a bed, and framed pictures on the wall.

A reception desk with a 'Welcome to Hampton' sign and a cityscape photograph.

6. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

Kathy

£83

includes taxes & fees

20 Oct - 21 Oct

A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

A modern living room with a fireplace, seating area, and a bar with shelves of bottles.

7. Hotel Hartness

Greenville

Kodjo

£155

includes taxes & fees

4 Oct - 5 Oct

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

A spacious lobby with a bar area, seating, and large windows.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

8. Hilton Garden Inn Spartanburg

Spartanburg

Yuliya

£106

includes taxes & fees

30 Oct - 31 Oct

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A pool area with lounge chairs and a sign for Best Western Plus.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

9. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

£63

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

10. Comfort Suites At WestGate Mall

Spartanburg

tara

£76

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A hotel room with two beds, a desk, a TV, and a patterned carpet.

A gym with treadmills, stationary bikes, and exercise balls.

11. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Shielder

£66

includes taxes & fees

18 Oct - 19 Oct

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

A large hotel with a central courtyard, surrounded by manicured lawns and trees.

12. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

£90

includes taxes & fees

11 Oct - 12 Oct

A modern outdoor seating area with a blue sofa, white armchairs, and a black fire pit.

A modern hotel building with a 'Stay Apt Suites' sign, featuring a large glass entrance and a parking area with cars.

13. stayAPT Suites Greenville Greer BMW

Greer

Robert

£92

includes taxes & fees

3 Oct - 4 Oct

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern building with a glass facade and a brick base, featuring a prominent entrance with a flag.

A large sports complex with multiple fields and tall light poles.

A gaming arcade with various machines and a colorful carpet.

14. Comfort Suites Greenville Airport

Greenville

Ryan

£80

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

15. Best Western Spartanburg Northwest

Spartanburg

Muhammad Awais

£79

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, seating area, and large windows.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

16. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Bogdan

£92

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass facade and a well-lit exterior.

A vending machine area with snacks and beverages, and a display of green apples.

17. Home2 Suites by Hilton Duncan

Duncan

Marina

£102

includes taxes & fees

25 Oct - 26 Oct

A modern restaurant with a brick wall, wooden ceiling beams, and a central seating area with tables and chairs.

A hallway with a wooden wall, a large abstract sculpture, and patterned flooring.

An outdoor patio with a fire pit, seating area, and a TV.

A snack and treat section with shelves stocked with various snacks, a chalkboard sign, and beverage dispensers.

18. Hampton Inn Greer Greenville, SC

Greer

Teresa

£118

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, green walls, and large black-and-white cityscape posters.

A hotel with a Super 8 sign, a swimming pool, and a covered patio area.

A reception desk with a glass door, a sign indicating 'Best US News Hotel', and a small statue on the counter.

19. Super 8 by Wyndham Greer/Spartanburg Area

Greer

Tom Frank Frith

£57

includes taxes & fees

10 Oct - 11 Oct

A modern lobby with a fireplace, comfortable seating, and a flat-screen TV.

A modern hotel lobby with a bar area, seating arrangements, and a visible menu board.

A modern lobby with a large screen displaying a cityscape, a dark wooden reception desk, and a tall vase with branches.

An outdoor seating area with wicker furniture and red cushions, surrounded by a stone fire pit.

20. Courtyard Greenville-Spartanburg by Marriott

Greer

Susan

£83

includes taxes & fees

18 Oct - 19 Oct

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Holiday Rentals in Upstate South Carolina

Aparthotel

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a microwave.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A two-story house with a front porch, a small garden, and a wooden fence.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Cabin

A cabin in a forest with a small deck and outdoor seating area.

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Aparthotel

A modern building with outdoor seating and a garden.

A row of modern, two-story buildings with a covered patio area.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A cozy living room with a dining table, sofas, and a chandelier.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A kitchen with a wooden countertop, a sink, a coffee maker, a toaster, and a window with a view of trees.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A dining area with a wooden table set for two, a blue chair, a small table with a lamp, and a kitchen in the background.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Apartment

A large house with a spacious driveway and a pond in the background.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.

A wooden bridge leading to a playground with green grass and trees.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A white house with a sloped roof, surrounded by trees and a garden.

Clemson Game Day Cottage w/ Fire Pit

Clemson

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.

A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent

"Really a great stay ."

Mint House Greenville Downtown by Kasa

10/10 Excellent

"The space was nice. The bathroom was clean albeit somewhat dated but for a couple of nights it was totally fine! The overall quality of the space, bed, balcony and location was great for the price. Would book again"

Lakeside Lodge Clemson

10/10 Excellent

"My first time here. Lovely resort. Pool was awesome. Poolside restaurant had good sandwiches. I wish the breakfast was open before 10:00 am, but the free coffee was nice. I walked to Starbucks for breakfast. Room was spacious."

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"clean room"

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"The room was very clean and comfortable. Staff was helpful and friendly. The lobby is to die for with the displays of Native American art and jewelry. A fun place e to stay with convenient location."

Comfort Inn & Suites Clemson - University Area

8/10 Good

"Great stay. Clean and conveniently located."

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

£59

26 Oct - 27 Oct

includes taxes & fees

8.4/10 Very good! (1,001 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

£63

18 Oct - 19 Oct

includes taxes & fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

£73

11 Oct - 12 Oct

includes taxes & fees

8.2/10 Very good! (1,002 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

£85

4 Oct - 5 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

£91

1 Nov - 2 Nov

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

£99

4 Oct - 5 Oct

includes taxes & fees

9/10 Wonderful! (1,001 reviews)

Hotels in Upstate South Carolina with star rating

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Find hotels in Upstate South Carolina, SC from £59

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Best Western Spartanburg I-26

2. Tru by Hilton Spartanburg

3. Four Points by Sheraton Spartanburg

4. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

5. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

6. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

7. Hotel Hartness

8. Hilton Garden Inn Spartanburg

9. Best Western Plus Greenville I-385 Inn & Suites

10. Comfort Suites At WestGate Mall

11. Fairfield Inn & Suites by Marriott Greenville Simpsonville

12. Embassy Suites Greenville Golf Resort & Conference Center

13. stayAPT Suites Greenville Greer BMW

14. Comfort Suites Greenville Airport

15. Best Western Spartanburg Northwest

16. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

17. Home2 Suites by Hilton Duncan

18. Hampton Inn Greer Greenville, SC

19. Super 8 by Wyndham Greer/Spartanburg Area

20. Courtyard Greenville-Spartanburg by Marriott

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Carolina Camp Cedar

Mint House Greenville Downtown by Kasa

Greer Guest House < 1 Mi to Park & Downtown Area!

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

The Station by Compo Hotels

Clemson Memorabilia House

Claires Cottage ~ 4 Mi to Downtown Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Clemson Game Day Cottage w/ Fire Pit

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Mint House Greenville Downtown by Kasa

Lakeside Lodge Clemson

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Grand Bohemian Lodge Greenville, Autograph Collection

Comfort Inn & Suites Clemson - University Area

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star rating

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