Find hotels in Upstate South Carolina, SC from £49
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16 Aug - 17 AugTomorrow
17 Aug - 18 AugNext weekend
21 Aug - 23 AugIn two weeks
28 Aug - 30 AugOur top choices for Upstate South Carolina hotels
1. Best Western Spartanburg I-26
Best Western Spartanburg I-26Spartanburg
Francisco
£69
includes taxes & fees
22 Aug - 23 Aug
2. Clarion Inn
Clarion InnGreenville
Mohamed Ayman
£61
includes taxes & fees
23 Aug - 24 Aug
3. Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
Jeremy
£80
includes taxes & fees
30 Aug - 31 Aug
4. Spartanburg Marriott
Spartanburg MarriottSpartanburg
Katherine
£97
includes taxes & fees
23 Aug - 24 Aug
5. AC Hotel by Marriott Spartanburg
AC Hotel by Marriott SpartanburgSpartanburg
shannon
£104
includes taxes & fees
23 Aug - 24 Aug
6. Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
Kristina
£72
includes taxes & fees
7 Sept - 8 Sept
7. Hampton Inn & Suites Greenville/Spartanburg I-85, SC
Hampton Inn & Suites Greenville/Spartanburg I-85, SCDuncan
Kathy
£90
includes taxes & fees
29 Aug - 30 Aug
8. Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
Carole
£68
includes taxes & fees
23 Aug - 24 Aug
9. Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
Travis
£98
includes taxes & fees
23 Aug - 24 Aug
10. Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHGDuncan
Jessie
£91
includes taxes & fees
16 Sept - 17 Sept
11. Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
Teresa
£116
includes taxes & fees
20 Aug - 21 Aug
12. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
Cole
£68
includes taxes & fees
18 Aug - 19 Aug
13. Hotel Hartness
Hotel HartnessGreenville
Cornelius
£162
includes taxes & fees
30 Aug - 31 Aug
14. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Nancy
£67
includes taxes & fees
30 Aug - 31 Aug
15. Hilton Garden Inn Spartanburg
Hilton Garden Inn SpartanburgSpartanburg
Stan
£97
includes taxes & fees
23 Aug - 24 Aug
16. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
Robert
£82
includes taxes & fees
23 Aug - 24 Aug
17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Hampton Inn & Suites Spartanburg-I-26-Westgate MallSpartanburg
michelle
£90
includes taxes & fees
23 Aug - 24 Aug
18. Courtyard by Marriott Greenville Mauldin
Courtyard by Marriott Greenville MauldinGreenville
sarah
£97
includes taxes & fees
20 Aug - 21 Aug
20. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
Michael
£77
includes taxes & fees
30 Aug - 31 Aug
Holiday Rentals in Upstate South Carolina
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Very relaxing, clean environment. Felt safe and welcoming."
Apartment
Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"Love the location. Room was great."
Cabin
Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Aparthotel
Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Aparthotel
stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"All the staff from front desk to housekeeping were excellent, friendly and helpful. If looking for rooms with a feel like home StayApt is what you are looking for. I recommend reserving here great place if you want to cook your own meals"
Aparthotel
The Station by Compo Hotels
The Station by Compo HotelsTravelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
Cottage
Claires Cottage ~ 4 Mi to Downtown Greenville!
Claires Cottage ~ 4 Mi to Downtown Greenville!Greenville
"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."
Cottage
Clemson Memorabilia House
Clemson Memorabilia HouseClemson
"We enjoyed our stay, it was the perfect size for our family of four. "
Cottage
2 Mi to Downtown: Luxe Greenville Retreat!
2 Mi to Downtown: Luxe Greenville Retreat!Greenville
"Great house! Very clean and comfortable. Outstanding amenities. Conveniently located. "
Cottage
Stay at Jos Taylor Retreat: 9 Mi to Greenville!
Stay at Jos Taylor Retreat: 9 Mi to Greenville!Taylors
"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."
Cottage
Families Welcome, Fenced Yard: Inviting Greer Home
Families Welcome, Fenced Yard: Inviting Greer HomeGreer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Cottage
Lake Access & Boat Slip: Greenwood Cottage!
Lake Access & Boat Slip: Greenwood Cottage!Greenwood
"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "
Cottage
1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Apartment
Serene Travelers Rest Apartment: 7 Mi to Downtown!
Serene Travelers Rest Apartment: 7 Mi to Downtown!Travelers Rest
"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "
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Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
Photo by Karyn Thompson
Fred W. Symmes Chapel
9.8/10 (29 reviews)
You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Martin Farm and Discovery Island Water Park.
See all hotels in Upstate South Carolina
Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Drury Inn & Suites Greenville
10/10 Excellent
"Breakfast was good and room clean"
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"yes"
Inn @ Clemson
10/10 Excellent
"The staff was welcoming and very helpful, as soon as we walked in the vibe was great! The room was clean, spacious and quiet. We will definitely be back!"
Hyatt Place Greenville/Haywood
10/10 Excellent
"Amazing place to stop on way to Clemson. Clean great pool and gym. Breakfast was good. Rooms were clean and comfortable!"
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"They were very accommodating to an early arrival as well as a pet friendly room. Breakfast was good."
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
10/10 Excellent
"We have stayed twice and both times were excellent"
The Shepherd Hotel Downtown Clemson
10/10 Excellent
"Our favorite place to stay in Clemson! Staff and atmosphere are fantastic!"
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"very convenient and close proximity to Clemson. Breakfast options are plentiful. On site restuarant."
Comfort Inn Greenville - Haywood Mall
8/10 Good
"Good"
More cheap stays in Upstate South Carolina
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
£49
30 Aug - 31 Aug
includes taxes & fees
5.6/10 (1,005 reviews)
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
£67
30 Aug - 31 Aug
includes taxes & fees
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
£72
23 Aug - 24 Aug
includes taxes & fees
8.2/10 Very good! (1,002 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
161 Sha Ln Spartanburg SC
£77
30 Aug - 31 Aug
includes taxes & fees
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
£83
18 Aug - 19 Aug
includes taxes & fees
8/10 Very good! (1,020 reviews)
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
£100
17 Aug - 18 Aug
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Hotels in Upstate South Carolina with star rating
4 Star Hotels
29 properties
3 Star Hotels
201 properties
2 Star Hotels
155 properties
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- Abbeville Hotels
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