Title: The 10 Best 4 Star Hotels in Upstate South Carolina - 2026 Updated Prices | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d553248635975748552.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d553248635975748552.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d553248635975748552.Holidays-City-Breaks) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Upstate South Carolina 4 Star Hotels Tonight [5 Mar - 6 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Mar - 7 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-03-06&endDate=2026-03-07&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina 4-star hotels ![Exterior](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/a7016c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (459 reviews) "The room was very clean, the food amazing, and the staff was efficient and friendly.Will definitely be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharlene £287 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (763 reviews) "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina £290 includes taxes & fees 13 Mar - 14 Mar [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (666 reviews) "The hotel was clean staff was amazing room was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford £143 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/93cc35df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville [](https://www.expedia.co.uk/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1,002 reviews) "Great hotel Great location Great room Friendly and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £156 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/3786343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/d192b91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville Downtown by Kasa [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (797 reviews) "Spotless wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanganica £83 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (570 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7ccc39b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Double Room | Premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/bd9ed0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/679dc208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.co.uk/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (83 reviews) "The owners are amazing. Comfy rooms, stellar breakfast and good people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee [](https://www.expedia.co.uk/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen | Full-sized fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Travelers Rest 10/10 Exceptional (17 reviews) "great place perfect for more privacy vs. a standard hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £231 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (31 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £345 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Apartment, 1 Bedroom | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/c1ffc683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/6a920723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch TV with digital channels](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/f6834f04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/39a13760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Place Apartments by Landing [](https://www.expedia.co.uk/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) Greenville 7.6/10 Good (46 reviews) "Loved the apartment! Very spacious, clean, brand new. Access to bike paths. Seemed like a quirky location but everything is close by car or bike. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathie [](https://www.expedia.co.uk/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/d429a622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/fe776675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/c6c3d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/116000000/115993600/115993513/7e1238ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steps to Lake Greenwood: Waterfront Gem w/ Patio [](https://www.expedia.co.uk/Greenwood-Hotels-Steps-To-Lake-Greenwood-Waterfront-Gem-W-Patio.h115993513.Hotel-Information) Greenwood 10/10 Exceptional (2 reviews) "Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luetrina [](https://www.expedia.co.uk/Greenwood-Hotels-Steps-To-Lake-Greenwood-Waterfront-Gem-W-Patio.h115993513.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/6608ac97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/896f48be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/fea470ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/580b23a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo: Resort Pools & Lake Access! [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) Salem 10/10 Exceptional (1 review) [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/8d8778c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/00f3abbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/9c4042e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/099a6462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxe Keowee Key Living: Golf Views & Resort Pool [](https://www.expedia.co.uk/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) Salem [](https://www.expedia.co.uk/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Interior](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/0dab2c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/a2d472c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Dining](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/d130503a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/cd2b74b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Sunshine Retreat [](https://www.expedia.co.uk/Easley-Hotels-Southern-Sunshine-Retreat.h111648957.Hotel-Information) Easley [](https://www.expedia.co.uk/Easley-Hotels-Southern-Sunshine-Retreat.h111648957.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/5525119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d3e3f6c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d726d506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/a31ab2bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Balcony: Lake Keowee Home w/ Pool Access [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) Salem [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/1a03e1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/461e3c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/bdf8c3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/9c5ca6a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views, Pools & Marina: Lake Keowee Condo! [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) Salem [](https://www.expedia.co.uk/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/fa41c5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f1051c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/be9143a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f8d4e496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 5 Mi to Memorial Stadium & Beach: Modern Townhome [](https://www.expedia.co.uk/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) Central [](https://www.expedia.co.uk/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/8692c837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/5314fa58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/ad6d8353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.co.uk/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/4fa0f099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/8810e390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/fac876d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/cd2123cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salem Vacation Rental w/ Lake Keowee Access! [](https://www.expedia.co.uk/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) Salem [](https://www.expedia.co.uk/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/fb4662cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/0ca3a49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/2ec7bf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9f6b4e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Resort Condo: Waterfront Balcony [](https://www.expedia.co.uk/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) Salem 10/10 Exceptional (1 review) "Very clean. Amazing amenities. Lake view that takes your breath away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany [](https://www.expedia.co.uk/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Upstate-South-Carolina-Hotels.s40-0-d553248635975748552.Travel-Guide-Filter-Hotels) ## Learn more about Upstate South Carolina Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park. [See all hotels in Upstate South Carolina](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-19&endDate=2026-03-20&adults=2®ionId=553248635975748552) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) Photo by Ryan Watts ## Top Upstate South Carolina Hotel Reviews ![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d_y.jpg) ### Hotel Hartness 10/10 Excellent "Great place" [](https://expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Perfectly located to walk to the river, downtown and peace center. Gorgeous asthetic, and pristine rooms, we loved the restaurant also! Staff we courteous and helpful in everyway. 10/10" [](https://expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "All was excellent" [](https://expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ## Find out more about Upstate South Carolina ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [1 Star Hotels in South Carolina Midlands ](https://www.expedia.co.uk/1Star-South-Carolina-Midlands-Hotels.s10-0-d6057938.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Greenville - Spartanburg ](https://www.expedia.co.uk/3Star-Greenville-Spartanburg-Hotels.s30-0-d6035267.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Greenville ](https://www.expedia.co.uk/4Star-Greenville-Hotels.s40-0-d1388.Travel-Guide-Filter-Hotels) - 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