Title: Holiday Rentals Upstate South Carolina from £106: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d553248635975748552.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d553248635975748552.Holidays-City-Breaks) ![Greenville - Spartanburg which includes views, tranquil scenes and mountains](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63748-Greenville-Spartanburg.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in Upstate South Carolina ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-10-12&endDate=2025-10-13&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-10-13&endDate=2025-10-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-10-17&endDate=2025-10-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-10-24&endDate=2025-10-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Holiday Rentals in Upstate South Carolina ![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/464c71ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/39f40af5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/88d2a0e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Greenville-Haywood Mall Greenville 9.2/10 Wonderful (186) "We throughly enjoyed our stay. We came down from Virginia for a concert at the CCNB Amphitheater. This place is now added on our list to come back to for quick stays! Very nice, and clean rooms! Thanks again!" £106 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information) ![Two Bedroom Suite | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a4b477d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/a1a743d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/18a2116d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Two Bedroom Suite | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/f7ce884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville - Downtown Greenville Downtown 9.2/10 Wonderful (743) "It was very clean and conveniently located. " £107 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/34f57420.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/90f42f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/2e79c007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537400/93537325/a0c41c40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wooded Cottage - 3 Mi to Clemson University Clemson 10/10 Exceptional (1) [](https://www.expedia.co.uk/Clemson-Hotels-Pet-Friendly-Central-Cottage-2-Miles-To-Clemson.h93537325.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/8c11b789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, stovetop, cookware/dishes/utensils, paper towels](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/18a62d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f5941a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/f29b16c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy Seneca 9.8/10 Exceptional (41) "The place was absolutely magnificent." [](https://www.expedia.co.uk/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/39a13760.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | 2 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/7d816d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | 40-inch TV with digital channels](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/689c7682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111140000/111130300/111130227/6a920723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Place Apartments by Landing Greenville 7.8/10 Good (40) "This was false advertising. Property name is not the same and their app did not work and we could not get into the property NOR get anyone on the phone. We spent 2 hours on the phone to try and get in and finally had to book another hotel. And it’s been a week and my money has yet to be returned even though Expedia said they would refund me " [](https://www.expedia.co.uk/Greenville-Hotels-Barsala-At-The-American-Spinning-Mill-Apartments.h111130227.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/83fe6802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/9ba3afd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/94af1b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87340000/87337600/87337581/41266a84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods Cleveland 9.8/10 Exceptional (104) "Great place to stay!" £111 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Cleveland-Hotels-Gnome-Hill-Cottage.h87337581.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/58000000/57860000/57854500/57854431/90607bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/58000000/57860000/57854500/57854431/b6497060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/58000000/57860000/57854500/57854431/0a401e88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/58000000/57860000/57854500/57854431/f4e6ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water. Seneca 9.8/10 Exceptional (152) "House is nice, description accurate about the walk from the house to the dock, not for any mobility issues.Fire pit setup great, kids did s’mores every night." [](https://www.expedia.co.uk/Anderson-Hotels-Newly-Furnished-And-Renovated-Lake-House-Directly-On-Hartwell.h57854431.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/118000000/117010000/117009500/117009436/eb7a660c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117010000/117009500/117009436/1b72e21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/118000000/117010000/117009500/117009436/6b096833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/118000000/117010000/117009500/117009436/45f2f590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Grandview: Luxe Home w Mountain Views Travelers Rest 10/10 Exceptional (1) "It was great! " £216 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Grandview-Luxe-Home-W-Mountain-Views.h117009436.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/436516e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/ff2ee17b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/9428aa30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/88000000/87560000/87552100/87552049/077dae4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson! Seneca 10/10 Exceptional (54) "Lovely lake house! Our family of four just loved it! The dock is great. Our dog swam like crazy and we used the kayaks. Totally stocked house with plenty of room for more than 4 people. We would definitely stay here again " [](https://www.expedia.co.uk/Seneca-Hotels-New-Peaceful-Lakefront-Home-On-Keowee-Only-7-Miles-From-Clemson.h87552049.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/efec02d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/fc94d8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/69fcdbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/67000000/66030000/66026900/66026894/76793b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Vacation Mountain Home Pickens 9.8/10 Exceptional (18) "Perfect size for our family! We wish we were in town longer. Great hot tub! " £258 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Pickens-Hotels-Luxury-Vacation-Mtn-Home.h66026894.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen | Full-sized fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area | Smart TV](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![ADA Vista Wedge Cottage | 1 bedroom, down duvets, individually decorated, individually furnished](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/38cc695c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels Travelers Rest 10/10 Exceptional (12) "Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!" £215 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19860000/19860000/19859961/26fe6567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/20000000/19860000/19860000/19859961/f009843d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19860000/19860000/19859961/8e057533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19860000/19860000/19859961/92b52a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanitized! Spacious Ranch Close To Gsp Airport, Greenville, Greer set on acres. Greenville 9.8/10 Exceptional (142) "Amazing property" [](https://www.expedia.co.uk/Greenville-Hotels-Sanitized-Spacious-Ranch-Close-To-Gsp-Airport.h19859961.Hotel-Information) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120920000/120911100/120911024/2a06ee27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/121000000/120920000/120911100/120911024/3a5103da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120920000/120911100/120911024/5a885db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120920000/120911100/120911024/a42bbd2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish Downtown Greenville Apartment 1 Block Off Main Street Greenville Downtown £126 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Stylish-Downtown-Greenville-Apartment1-Block-Off-Main-Street.h120911024.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88310000/88305600/88305541/e0c42fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/89000000/88310000/88305600/88305541/94b39780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/89000000/88310000/88305600/88305541/887370fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, premium bedding, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/89000000/88310000/88305600/88305541/f58fd3ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Door Apartment | 3-KING Beds | Center Of Downtown Greenville Greenville Downtown 9.8/10 Exceptional (77) "Perfect location and wonderful spacious apartment! " £377 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Red-Door-Apartment-3-KING-Beds-Center-Of-Downtown-Greenville.h88305541.Hotel-Information) ![](https://images.trvl-media.com/lodging/28000000/27140000/27132300/27132247/08762fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/28000000/27140000/27132300/27132247/37f3fed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/28000000/27140000/27132300/27132247/84b0f5dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player](https://images.trvl-media.com/lodging/28000000/27140000/27132300/27132247/05c0eb72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Penthouse With Terrace, 1/2 block from Main St in the heart of downtown Greenville Downtown 10/10 Exceptional (215) "Great time in Greenville! Food, Fun and Family!" [](https://www.expedia.co.uk/Greenville-Hotels-Downtown-Penthouse-With-Terrace.h27132247.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/w715h535x173y8-4b719005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/w714h537x157y0-fa49dce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/0bea6995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/99000000/98530000/98527500/98527491/d3238b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail! Greenville 9.4/10 Exceptional (21) "The unit was very nice inside. The bedding was very comfortable. It was much better than staying in a hotel. Easy to get to downtown or anywhere you are wanting to go. " £133 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Greenville-Hotels-2BR-Cedar-Lane-Road-Retreat-At-Swamp-Rabbit-Trail.h98527491.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96670000/96666800/96666780/w1024h573x0y55-9f9a0d8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96670000/96666800/96666780/w449h683x287y0-6578c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96670000/96666800/96666780/w1024h572x0y56-1857aa6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96670000/96666800/96666780/w904h683x60y0-89d8b11a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny House - Slice of Heaven Walhalla Walhalla 9.4/10 Exceptional (27) "Nice serene location" £157 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Walhalla-Hotels-Tiny-House-Slice-Of-Heaven-Walhalla.h96666780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103530000/103524500/103524449/94362537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103530000/103524500/103524449/12bfe05a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103530000/103524500/103524449/fe37c291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/104000000/103530000/103524500/103524449/f3d0d2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Enjoy your stay in the West End of Greenville in our Mill Village House Greenville 10/10 Exceptional (16) "Loved everything about our stay! Property was just as advertised, close to downtown and so cute! We will definitely come back here on our next visit to Greenville." [](https://www.expedia.co.uk/Greenville-Hotels-Enjoy-Your-Stay-In-The-West-End-Of-Greenville-In-Our-Mill-Village-House.h103524449.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/67cc829e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/4d05ab51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, stereo](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/cde4fe9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, stereo](https://images.trvl-media.com/lodging/28000000/27120000/27118400/27118346/70a34410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock Seneca 9.6/10 Exceptional (172) "Such a great place to stay! The house has literally everything you could need to enjoy your stay. From cooking to recreation to cozy comforts of home. We will definitely stay here again. Carl and Erica G" [](https://www.expedia.co.uk/Seneca-Hotels-Quiet-Cove.h27118346.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/70000000/69730000/69721900/69721813/9de82f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/70000000/69730000/69721900/69721813/2016bfb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/70000000/69730000/69721900/69721813/e763fd1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69730000/69721900/69721813/13629c17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverwalk Falls-lovely one bedroom condo Greenville Downtown 10/10 Exceptional (168) "Great spot. Very convenient to all downtown activity. We parked and didn’t get in the car all weekend. " £190 includes taxes & fees 28 Oct - 29 Oct [](https://www.expedia.co.uk/Greenville-Hotels-Riverwalk-Falls-Lovely-One-Bedroom-Condoloft.h69721813.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=553248635975748552&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Holiday-Rentals.d553248635975748552.Travel-Guide-HolidayRentals)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Holiday-Rentals.d553248635975748552.Travel-Guide-HolidayRentals) ## Top Upstate South Carolina Hotel Reviews ![Hyatt Place Greenville Downtown](//images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "Good value and location " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Awesome " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Comfort Suites Greenville Airport](//images.trvl-media.com/lodging/47000000/46120000/46116400/46116309/9d9a99c3_y.jpg) ### Comfort Suites Greenville Airport 10/10 Excellent "Lovely view of top golf. Very clean and spacious room" [](https://expedia.co.uk/Greenville-Spartanburg-Hotels-Comfort-Suites.h46116309.Hotel-Information) ![Hampton Inn & Suites Greenville Airport, SC](//images.trvl-media.com/lodging/12000000/11920000/11919200/11919192/de1bb5e2_y.jpg) ### Hampton Inn & Suites Greenville Airport, SC 10/10 Excellent "Clean room " [](https://expedia.co.uk/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Airport.h11919192.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](//images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Great location with a great rooftop restaurant! Our room had a beautiful view from our patio!" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](//images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 10/10 Excellent "Nice quiet, clean room. Met our expectations." [](https://expedia.co.uk/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "I enjoyed my stay here. It was very clean and cozy. I will make another stay here, if available for my next travel. Thank you! " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](//images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Very nice property. I would stay there again." [](https://expedia.co.uk/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](//images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Very friendly. Great coffee and breakfast. Hotel was clean and convenient " [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ## Find out more about Upstate South Carolina **Everything you need to know about** **Upstate South Carolina** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **Upstate South Carolina holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Upstate South Carolina holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Upstate South Carolina holiday rentals we have selected for you start as low as £106 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Upstate South Carolina rentals** At Expedia, we put the best Upstate South Carolina holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk - All accommodation types in Upstate South Carolina ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - 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