Upstate South Carolina Holidays from £1,323
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Your Upstate South Carolina Holiday
With a Upstate South Carolina holiday package, you can forget about the stress of planning and simply focus on experiencing what this thrilling destination has on offer. With so much to do and see on a trip to Upstate South Carolina, it can be hard to know where to begin. Kick off your travels in Greenville at Falls Park on the Reedy and Bon Secours Wellness Arena — two popular attractions here. Another top city worthy of a spot on your itinerary is Spartanburg. Don't miss WestGate Mall and Tyger River Park. Expedia is your one-stop shop for planning your Upstate South Carolina holiday. From hotels and flights, to car rentals and more, we're here to help you create a travel experience like no other.
Top Upstate South Carolina Flight + Hotel Deals
Charlotte Marriott City Center
Reviewed on 13 Apr 2026
Hyatt House Charlotte/Rea Farms
Reviewed on 12 Apr 2026
Homewood Suites By Hilton Charlotte Uptown First Ward
Reviewed on 13 Apr 2026
Where to stay in Upstate South Carolina
Greenville Downtown
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charleston Intl. Airport (CHS) |
Top hotels in Upstate South Carolina
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Great place to stay.
Reviewed on 12 Apr 2026
Hilton Greenville
Two of the three elevators were broken. They charge for using their parking lot. It's not even near a city. Had to request clean towels.
Reviewed on 13 Apr 2026
Embassy Suites Greenville Golf Resort & Conference Center
Staff is friendly and helpful! Clean room. Easy access to airport.
Reviewed on 13 Apr 2026
Popular places to visit
Fred W. Symmes Chapel
You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.
Devils Fork State Park
You can take time to visit Devils Fork State Park during your travels to Salem. Wander the lakeside or discover the area's mountain views.
Tyger River Park
Catch an event at Tyger River Park during your trip to Spartanburg. While in this family-friendly area, you can savour the top-notch restaurants.
What to do in Upstate South Carolina
Paranormal Walking Tour by Greenville Ghost Tours
Frequently asked questions
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- Anglewood Hotels
- Enoree Hotels
- Fingerville Hotels
- Fountain Inn Hotels
- Gray Court Hotels
- Pauline Hotels
- Roebuck Hotels
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- Hotels near Spartanburg Downtown Memorial
- Spartanburg Historic District Hotels
- Beach Resorts & in Spartanburg
- Cheap Hotels in Spartanburg
- Business Hotels in Spartanburg
- Family-Friendly Hotels in Spartanburg
- Hotels Suites in Spartanburg
- Hotels with Connecting Rooms in Spartanburg
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- Spa Hotels in Spartanburg
- Spartanburg Hotels
- Startex Hotels
- Hotels near WestGate Mall
- Woodruff Hotels
- Flights to Spartanburg
- Flights to Woodruff
- Flights from Spartanburg Downtown Memorial
- Flights from Fairforest
- Flights from Pauline
- Flights from Startex
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- Flights from Amsterdam (AMS) to Spartanburg (SPA)
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- Bi Lo Center
- Chesnee Holidays
- Discovery Island Water Park
- Duncan Holidays
- First Presbyterian Church
- Frankie's Fun Park
- Gaffney Holidays
- Greenville - Spartanburg Holidays
- Greenville Holidays
- Historic Greer Depot
- Inman Holidays
- Joanna Holidays
- Laurens County Courthouse
- Laurens Holidays
- Musgrove Mill State Historic Site
- North Grove Medical Park
- Patewood Memorial Hospital
- Visit Roebuck
- Simpsonville Holidays
- Southern Shops Holidays
- Spartanburg Expo Center
- Spartanburg Holidays
- Visit Spartanburg
- Taylors Holidays
- The Price House
- Travelers Rest Holidays
- Tyger-10 Nature Park
- Tyger River Park
- University Square Shopping Center
- Upstate South Carolina Holidays
- Wade Hampton Mall Shopping Center
- Warehouse Theatre
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.