Southwest Illinois adults only hotels from £53

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Top Adults only hotels in Southwest Illinois

The Principal Hotel
3.5 out of 5
310 S Main St, Columbia, IL
The price is £85 per night from 31 Aug to 1 Sept
£85
31 Aug - 1 Sept
includes taxes & fees
9.8/10 Exceptional! (122 reviews)
"Overall was the best stay we have had with any one. The only downside would be no hot breakfast unless you went to the restaurant on location. Staff was great and so helpful when we needed anything for the room."

Reviewed on 18 Aug 2025

The Principal Hotel
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
The price is £80 per night from 7 Sept to 8 Sept
£80
7 Sept - 8 Sept
includes taxes & fees
9.6/10 Exceptional! (1,431 reviews)
"Nice clean rooms, great and very helpful staff."

Reviewed on 24 Aug 2025

Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Collinsville
3 out of 5
602 N Bluff Rd, Collinsville, IL
The price is £95 per night from 31 Aug to 1 Sept
£95
31 Aug - 1 Sept
includes taxes & fees
9.6/10 Exceptional! (1,002 reviews)
Would stay again
"Hotel was clean and up to date. The staff was friendly and amenities great!"

Reviewed on 25 Aug 2025

Drury Inn & Suites St. Louis Collinsville
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
The price is £86 per night from 7 Sept to 8 Sept
£86
7 Sept - 8 Sept
includes taxes & fees
9.4/10 Exceptional! (471 reviews)
"We had to leave before breakfast was offered so that was disappointing. The area was nice and clean though and the rooms were spacious. We would stay here again."

Reviewed on 24 Aug 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Drury Inn & Suites Marion
3 out of 5
2706 W DeYoung St, Marion, IL
The price is £87 per night from 7 Sept to 8 Sept
£87
7 Sept - 8 Sept
includes taxes & fees
9.2/10 Wonderful! (1,002 reviews)
"Top of the line!"

Reviewed on 22 Aug 2025

Drury Inn & Suites Marion
SureStay Hotel by Best Western Whittington Rend Lake
2.5 out of 5
13277 Freeway Lane, Whittington, IL
The price is £56 per night from 2 Sept to 3 Sept
£56
2 Sept - 3 Sept
includes taxes & fees
8.8/10 Excellent! (852 reviews)
"The room was a little musty smelling but otherwise it was comfortable."

Reviewed on 24 Aug 2025

SureStay Hotel by Best Western Whittington Rend Lake
Holiday Inn Express & Suites Vandalia by IHG
2.5 out of 5
21 Mattes Ave, Vandalia, IL
The price is £98 per night from 31 Aug to 1 Sept
£98
31 Aug - 1 Sept
includes taxes & fees
8.8/10 Excellent! (728 reviews)
"Clean and right off the highway."

Reviewed on 23 Aug 2025

Holiday Inn Express & Suites Vandalia by IHG
Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 out of 5
1920 Kennedy Boulevard, Vandalia, IL
The price is £53 per night from 2 Sept to 3 Sept
£53
2 Sept - 3 Sept
includes taxes & fees
8.2/10 Very Good! (1,006 reviews)
Quiet property. Good condition.
"Check in was quick and easy. The property is older, but in good condition. Room was clean. We got to breakfast toward the end there was limited eggs and sausage remaining. Also had waffles and yogurt. The property is quiet. Those other complaints concerns."

Reviewed on 22 Aug 2025

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
The price is £76 per night from 1 Sept to 2 Sept
£76
1 Sept - 2 Sept
includes taxes & fees
8.2/10 Very Good! (1,031 reviews)
Very good service.
"We have stayed here before. Very nice hotel and friendly staff. For some reason, we got an accessible room instead of a standard. Desk clerk was very helpful to change it out."

Reviewed on 23 Aug 2025

Baymont by Wyndham Marion
Best Western Marion Hotel
2.5 out of 5
400 Comfort Dr, Marion, IL
The price is £63 per night from 2 Sept to 3 Sept
£63
2 Sept - 3 Sept
includes taxes & fees
8/10 Very Good! (1,003 reviews)
"Good area near shopping area and restaurants. Close to Hwy and convenience."

Reviewed on 19 Aug 2025

Best Western Marion Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find Romantic Hotels in Southwest Illinois

Cozy Cottage On The Shawnee Hills Wine Trail

Cozy Cottage On The Shawnee Hills Wine Trail

Cobden, IL
Get rates
9.8/10 Exceptional! (158 reviews)

Frequently Asked Questions

How can I find the best adults only resorts in Southwest Illinois?

The best adults only resort for you is deeply personal. First off, decide what you want from your dream holiday, then use our filters to bring it to life. Find resorts with hot tubs, spas and incredible views, then check out the reviews to see how other guests enjoyed their stay.

How much does a Southwest Illinois adults-only hotel cost?

With Expedia, you can find adults only hotels from £53 to per night. Prices and availability are subject to change. Additional terms may apply.

How can I find an adults only all-inclusive holiday in Southwest Illinois?

It’s simple. Just select the all-inclusive filter to find the best resorts where you can eat, drink and holiday to your heart’s content.

What can I expect from Southwest Illinois 5-star all-inclusive adults only hotels?

Luxury comes as standard in the 5-star resorts of Southwest Illinois. Step into spotless surroundings, stellar service and all the amenities your heart desires, from spas and pools to casinos and cocktail bars.

Why should I book a Southwest Illinois adults only hotel with entertainment?

When you book an adult only hotel with entertainment, pack your bags to get dolled up for the very best of comedy, cabaret, music, magic and much more – all just steps from your room.

How can I find the best deals on adults only resorts in Southwest Illinois?

To find amazing deals in Southwest Illinois and for a quieter experience, book your holiday in . The more flexible you can be with your dates, the better your chances are of getting a fantastic wallet-friendly deal. You can always check out our latest cheap deals for a little inspiration.

Do adults only hotels in Southwest Illinois offer free cancellation?

Some adults only hotels here offer free cancellation. Some don’t. It’s always best to check before you book. You can filter by free cancellation and pay later options to find resorts with that extra flexibility you want.

Why should I book my adults only resort in Southwest Illinois with Expedia?

At Expedia, we put everything you need to book your dream trip in one place. With a vast selection of incredible adult only accommodation at your fingertips, all that’s left to do is set your sights on what’s right for you.