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Top 10 Southwest Illinois hotels and places to stay

Our top choices for Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1442)
"Great place like a vacation every time I stay "
The price is £79
includes taxes & fees
7 Sept - 8 Sept
Drury Plaza Hotel Mt. Vernon

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (853)
"The staff was friendly and very helpful."
The price is £55
includes taxes & fees
7 Sept - 8 Sept
SureStay Hotel by Best Western Whittington Rend Lake

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
8.4 out of 10, Very good, (1012)
"Will stay again."
The price is £57
includes taxes & fees
1 Sept - 2 Sept
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1011)
"Nice hotel. Would stay here again."
The price is £91
includes taxes & fees
1 Sept - 2 Sept
Comfort Suites Mount Vernon

Holiday Inn Express & Suites Vandalia by IHG

2.5 star property
8.8 out of 10, Excellent, (733)
"Clean and right off the highway."
The price is £94
includes taxes & fees
3 Sept - 4 Sept
Holiday Inn Express & Suites Vandalia by IHG

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1011)
"We had an excellent stay."
The price is £83
includes taxes & fees
1 Oct - 2 Oct
Drury Inn & Suites Marion

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (475)
"Rooms were clean and comfy, great breakfast "
The price is £85
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (125)
"Perfect stay! "
The price is £85
includes taxes & fees
2 Sept - 3 Sept
The Principal Hotel

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very good, (1037)
"We stayed overnight for work and were very impressed with the hotel."
The price is £73
includes taxes & fees
14 Sept - 15 Sept
Baymont by Wyndham Marion

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very good, (1008)
"Nice motel for a decent price."
The price is £63
includes taxes & fees
2 Sept - 3 Sept
Best Western Marion Hotel

Best Western Plus MidAmerica Hotel

2.5 star property
9.0 out of 10, Wonderful, (1012)
"Extremely friendly staff, great location, safe for a solo traveler "
The price is £92
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus MidAmerica Hotel

Comfort Inn & Suites Marion I-57

2.5 star property
9.2 out of 10, Wonderful, (1007)
"Very nice and clean, friendly staff, good breakfast too."
The price is £95
includes taxes & fees
1 Oct - 2 Oct
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Greenville I-70

2.5 star property
8.4 out of 10, Very good, (398)
"good place to stay"
The price is £78
includes taxes & fees
21 Sept - 22 Sept
Comfort Inn & Suites Greenville I-70

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Great place to stay "
The price is £95
includes taxes & fees
8 Sept - 9 Sept
Drury Inn & Suites St. Louis Collinsville

Best Western Plus Centralia Hotel & Suites

2.5 star property
9.6 out of 10, Exceptional, (568)
"Clean and kind staff!"
The price is £115
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus Centralia Hotel & Suites

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property
9.2 out of 10, Wonderful, (1012)
"Great stay! "
The price is £78
includes taxes & fees
11 Sept - 12 Sept
Drury Inn & Suites St. Louis Fairview Heights

Super 8 by Wyndham Greenville

2.0 star property
8.0 out of 10, Very good, (729)
"It’s not super fancy, as you’d expect, but the place was decent and seemed clean, the staff was very friendly and helpful, and the prices are decent if you need a quick stay. "
The price is £52
includes taxes & fees
7 Sept - 8 Sept
Super 8 by Wyndham Greenville

Ramada by Wyndham Vandalia

2.0 star property
7.8 out of 10, Good, (786)
"It was clean and the bed was comfortable. Yhe pillows sucked though. "
The price is £55
includes taxes & fees
3 Sept - 4 Sept
Ramada by Wyndham Vandalia

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

2.5 star property
8.8 out of 10, Excellent, (667)
"Great place to stay"
The price is £95
includes taxes & fees
12 Sept - 13 Sept
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Baymont by Wyndham Chester IL

2.5 star property
8.6 out of 10, Excellent, (332)
"Quiet area with comfortable rooms and very helpful staff!"
The price is £61
includes taxes & fees
4 Sept - 5 Sept
Baymont by Wyndham Chester IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southwest Illinois, IL

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Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

Southern Illinois which includes a lake or waterhole and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southwest Illinois Hotel Reviews

More cheap stays in Southwest Illinois

More cheap stays in Southwest Illinois

Hotels in Southwest Illinois with star rating

Hotels in Southwest Illinois with star rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where can I find the best nightlife in Southwest Illinois?
Southwest Illinois has a charming and diverse nightlife scene, particularly in its larger towns and cities.

In Belleville, you can explore the lively downtown area, which is brimming with bars and restaurants offering a variety of atmospheres. From relaxed pubs to energetic dance spots, there's something for everyone. The local breweries have also gained popularity, providing a great place to enjoy craft beer with friends.

If you venture to Edwardsville, you'll find a vibrant nightlife scene as well. The historic downtown is home to an array of trendy bars, live music venues, and laid-back eateries, superb for unwinding after a long day. The atmosphere here is friendly and welcoming, making it a great spot for both locals and visitors.

For those looking for a more suburban vibe, the nightlife in O'Fallon features several family-friendly establishments with late-night dining options, along with a selection of pubs that often host live music. It's ideal for a relaxed evening out with good food and entertainment.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Southwest Illinois hotel for you.
How can I save on a Southwest Illinois hotel booking with Expedia?
Members always get our best prices. Find our best Southwest Illinois hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Southwest Illinois hotel?
Prices for hotels in Southwest Illinois often vary, but you can find a great deal from £43 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.