Compare and book 5 Star hotels in Southern Illinois, Illinois

    price find illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Southern Illinois 5 Star Hotels

Tonight
5 Jul - 6 Jul
Tomorrow
6 Jul - 7 Jul
Next weekend
11 Jul - 13 Jul
In two weeks
18 Jul - 20 Jul

Top Southern Illinois 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southern Illinois.
DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

222 Potomac Blvd, Mount Vernon, IL
The price is £108 per night from 13 Jul to 14 Jul
£108
13 Jul - 14 Jul
includes taxes & fees
8.2/10 Very Good! (705 reviews)
Still don't see what you're looking for?
See all properties in Southern Illinois.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southern Illinois

Experience the family-friendly area of Southern Illinois—live music, an opera house and sights from Jefferson County Fairgrounds to Salem Fairgrounds.

See all hotels in Southern Illinois
Southern Illinois featuring landscape views, a sunset and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Southern Illinois?
There are many different pricing options for a 5-star hotel in Southern Illinois on Expedia. The amount you pay will depend on when you want to travel, length of stay and other factors. Compare all of the available properties for your chosen dates and make use of our pricing and other filters to find the ideal luxury stay.

  • Search for the lowest price per night from £100

What makes a hotel 5 stars in Southern Illinois?
In Southern Illinois, a hotel must offer a certain level of high-end conveniences to be rated 5 stars. These can include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-centric standard of service. You can look forward to things like in-room massages, nightly turn-down services and concierge services. Some may even offer thoughtful touches such as welcome gifts.
Are there any 5-star all-inclusive resorts in Southern Illinois?
Our convenient filters are the quickest way to search for exactly what you're looking for. Select "All inclusive" and "5-star" to show the finest properties in Southern Illinois where your lodging, meals, entertainment and activities are included in the price. At these escapes, your trip is pure leisure from the moment you pull up to the entrance.